MITSUAKI TAKEMI

Last Updated :2025/12/19

Affiliations, Positions
Graduate School of Advanced Science and Engineering, Associate Professor (tenured)
Web Site
https://lit.link/en/takemi1988
E-mail
mtakemihiroshima-u.ac.jp
Other Contact Details
1-4-1 Kagamiyama, Higashi-hiroshima 739-8527, Japan
TEL : (+81)82-424-4584 FAX : (+81)
Self-introduction
Mitsuaki Takemi's research focuses on the enhancement of the process acquiring new motor skills and knowledge. The main research methods used are neurofeedback, non-invasive brain stimulation and kinematic motor analysis. He is also working on the creation of a guidebook on the current status and issues of such technologies and organising evidence through systematic reviews, with the aim of creating appropriate social awareness of 'neurotechnology' (brain tech), which is the civilian application of neuroscience findings.

Basic Information

Major Professional Backgrounds

  • 2025/04, Hiroshima University, Graduate School of Advanced Science and Engineering, Associate Professor
  • 2021/04, 2025/03, Keio University, Graduate School of Science and Technology, Project Assistant Professor
  • 2018/10, 2022/03, Japan Science and Technology Agency, PRESTO researcher
  • 2018/10, 2021/03, The University of Tokyo, Graduate School of Education, Project researcher
  • 2016/04, 2018/09, The University of Tokyo, Graduate School of Education, Postdoc
  • 2015/10, 2018/10, Japan Society for the Promotion of Science, JSPS Research Fellowship for Young Scientists (PD)
  • 2015/04, 2017/03, Danish Research Centre for Magnetic Resonance, Postdoc researcher
  • 2014/04, 2015/09, Japan Society for the Promotion of Science, JSPS Research Fellowship for Young Scientists (DC2)
  • 2013/10, 2014/03, Keio Univeristy, Graduate School of Science and Technology, Research Associate (Fixed-term)

Educational Backgrounds

  • Keio University, Graduate School of Science and Technology (PhD), 2012/09, 2015/09
  • Keio University, Graduate School of Science and Technology (MSc), 2011/04, 2012/09
  • Keio University, Faculty of Science and Technology, Department of Bioscience and Informatics, 2007/04, 2011/03

Academic Degrees

  • Keio University
  • Keio University

Educational Activity

  • [Bachelor Degree Program] School of Engineering : Cluster 2(Electrical, Electronic and Systems Engineering) : Program of Electrical,Systems and Information Engineering
  • [Master's Program] Graduate School of Advanced Science and Engineering : Division of Advanced Science and Engineering : Electrical, Systems, and Control Engineering Program
  • [Master's Program] Graduate School of Advanced Science and Engineering : Division of Advanced Science and Engineering : Smart Innovation Program
  • [Doctoral Program] Graduate School of Advanced Science and Engineering : Division of Advanced Science and Engineering : Electrical, Systems, and Control Engineering Program
  • [Doctoral Program] Graduate School of Advanced Science and Engineering : Division of Advanced Science and Engineering : Smart Innovation Program

In Charge of Primary Major Programs

  • Program of Electrical,Systems and Information Engineering

Research Fields

  • Complex systems;Brain sciences;Brain biometrics
  • Complex systems;Health / Sports science;Developmental mechanisms and the body works

Research Keywords

  • Neurotechnology
  • Electroencephalogram
  • Electromyogram
  • Neurofeedback
  • Non-invasive brain stimulation
  • Biosignal processing
  • Motor control
  • Motor learning
  • Systematic review
  • Meta-analysis

Affiliated Academic Societies

  • THE JAPAN NEUROSCIENCE SOCIETY
  • The Japanese Society for Motor Control
  • Society for neuroscience
  • Society for the Neural Control of Movement

Research Activities

Academic Papers

  1. Electroencephalographic Biomarkers of Relaxation: A Systematic Review and Meta-analysis, Journal of Cognitive Neuroscience, 20250929
  2. Synchronized application of closed-loop NMES and precision tACS in post-stroke hand rehabilitation: a protocol of neurorehabilitation trial., Therapeutic advances in chronic disease, 15, 20406223241297397, 202411
  3. Theta oscillations in observers' temporal cortex index postural instability of point-light displays, Neuroscience, 202410
  4. Posture-dependent modulation of marmoset cortical motor maps detected via rapid multichannel epidural stimulation, Neuroscience, 202410
  5. ★, Pre-movement muscle co-contraction associated with motor performance deterioration under high reward conditions, Scientific Reports, 14(1), 20240719
  6. Two common issues in synchronized multimodal recordings with EEG: Jitter and latency, Neuroscience Research, 203, 1-7, 202406
  7. Efficacy of neurofeedback training for improving attentional performance in healthy adults: A systematic review and meta-analysis, Imaging Neuroscience, 2, 1-23, 20240105
  8. Behavioral and physiological fatigue-related factors influencing timing and force control learning in pianists, Scientific Reports, 13(1), 20231208
  9. ★, An investigation of the effectiveness of neurofeedback training on motor performance in healthy adults: A systematic review and meta-analysis., NeuroImage, 270, 120000-120000, 20230302
  10. Multipulse transcranial magnetic stimulation of human motor cortex produces short-latency corticomotor facilitation via two distinct mechanisms., Journal of neurophysiology, 129(2), 410-420, 20230201
  11. ★, Spectral Power in Marmoset Frontal Motor Cortex during Natural Locomotor Behavior, Cerebral Cortex, 31(2), 1077-1089, 202102
  12. Cortical reorganization of lower-limb motor representations in an elite archery athlete with congenital amputation of both arms., NeuroImage. Clinical, 25, 102144-102144, 20191224
  13. ★, Muscle-selective disinhibition of corticomotor representations using a motor imagery-based brain-computer interface, NeuroImage, 183, 597-605, 201812
  14. Accurate motor mapping in awake common marmosets using micro-electrocorticographical stimulation and stochastic threshold estimation, Journal of Neural Engineering, 15(3), 036019, 20180406
  15. ★, Cortical control of object-specific grasp relies on adjustments of both activity and effective connectivity: a common marmoset study, JOURNAL OF PHYSIOLOGY-LONDON, 595(23), 7203-7221, 201712
  16. Rapid Identification of Cortical Motor Areas in Rodents by High-Frequency Automatic Cortical Stimulation and Novel Motor Threshold Algorithm, Frontiers in Neuroscience, 11(580), 20171017
  17. Synchronizing the transcranial magnetic pulse with electroencephalographic recordings effectively reduces inter-trial variability of the pulse artefact, PLOS ONE, 12(9), e0185154, 201709
  18. SENSORIMOTOR EVENT-RELATED DESYNCHRONIZATION REPRESENTS THE EXCITABILITY OF HUMAN SPINAL MOTONEURONS, NEUROSCIENCE, 297, 58-67, 201506
  19. Three-dimensional motion analysis of arm-reaching movements in healthy and hemispinalized common marmosets, BEHAVIOURAL BRAIN RESEARCH, 275, 259-268, 201412
  20. ★, Event-related desynchronization reflects downregulation of intracortical inhibition in human primary motor cortex, JOURNAL OF NEUROPHYSIOLOGY, 110(5), 1158-1166, 201309

Publications such as books

  1. 2024, NeuroTech Guidebook vol.2: For Responsible Development by Enterprise, NeuroTech Guidebook vol.2: For Responsible Development by Enterprise, NeuroTech Guidebook Development Committee, Joint editor
  2. 2023, NeuroTech Evidence Book : Examining NeuroTech's Efficacy and Safety, NeuroTech Evidence Book : Examining NeuroTech's Efficacy and Safety, Neurotech Guidebook Development Committee Secretariat, Editor, Neurotech Evidence Evaluation Committee
  3. 2022, NeuroTech Guidebook: Where is NeuroTech Today?, NeuroTech Guidebook: Where is NeuroTech Today?, Secretariat, Joint editor, NeuroTech Guidebook Development Committee

Invited Lecture, Oral Presentation, Poster Presentation

  1. Building a Trustworthy Future for Neurotechnology, Mitsuaki Takemi, The 27th Annual Meeting of Japan Human Brain Mapping Society, 2025/03/08
  2. Promoting Public Trust in Neurotechnology: A Comprehensive Guidebook and Evidence-Based Approach, Mitsuaki Takemi; Ryota Kanai, Real-Time Functional Imaging and Neurofeedback meeting 2024, 2024/11/05
  3. Promoting Public Trust in Neurotechnology: Bridging the Gap between Hype and Reality, Mitsuaki Takemi, 27th annual meeting of the Korean Society for Brain and Neural Sciences, 2024/10/16
  4. Effectiveness of neurofeedback training in motor performance, Mitsuaki Takemi, 33rd International Congress of Clinical Neurophysiology, 2024/09/13
  5. Robotic TMS: automatic measures of the motor hot point, motor threshold, and SICI, Mitsuaki Takemi, 33rd International Congress of Clinical Neurophysiology, 2024/09/12
  6. Towards Trusted Neurotechnology - A Moonshot Project -, Mitsuaki Takemi, The 46th Annual Meeting of the Japan Neuroscience Socity, 2023/08/02
  7. Diversifying the frequency of gamma-oscillatory brain stimulation during encoding enhances recognition memory, Mitsuaki Takemi; Daichi Nozaki, 44th Annual Meeting of the Japan Neuroscience Society, 2021/07/28
  8. The hot and cold streaks in reinforcement learning, Mitsuaki Takemi; Risa Saito; Midori Kodama; Daichi Nozaki, 30th Annual NCM Meeting, 2021/04/22
  9. Evaluation and manipulation of cortical activities using EEG-TMS, Mitsuaki TAKEMI, 50th Conference on Japanese Society of Clinical Neurophysiology, 2020/11/26
  10. Focal transcranial alternating current stimulation to the sensorimotor hand area at individual alpha and beta rhythm, Mitsuaki Takemi, DRCMR-Keio Rehab Neuroscience Joint Symposium, 2019/10/11
  11. Motor Practice under Variable Brain States Elicited by Transcranial Direct Current Stimulation, Mitsuaki Takemi, The 3rd Annual Neuromechanics and Motor Control Meeting, 2019/09/16
  12. EEG-triggered TMS for unraveling human sensorimotor EEG function, Mitsuaki TAKEMI, 48th Conference on Japanese Society of Clinical Neurophysiology, 2018/11/08
  13. Dynamic muscle representations in marmoset motor cortex: Static lower limb position modulates upper limb motor somatotopy, Iriki A; Takemi M; Tia B; Kosugi A; Castagnola E; Ricci D; Fadiga L; Ushiba J, Nanosymposium "The Marmoset Brain: Brain Mapping and Circuit Tracing" at the 48th SfN meeting, 2018/11/05
  14. Noninvasive brain stimulation: Present situation and future directions, Mitsuaki TAKEMI, A Seminar at NCGG Center of Assistive Robotics and Rehabilitation, 2018/05/14
  15. Realtime EEG-state dependent TMS in human sensorimotor cortex, Mitsuaki TAKEMI, 11th conference on the Japanese Society for Motor Control, 2017/08/25
  16. Moving towards neural engineering to overcome limitations in transcranial brain stimulation, Mitsuaki TAKEMI, A Seminar on biological information processing at TUAT, 2017/01/05
  17. A new algorithm for short-time motor mapping by epidural cortical stimulation in rats, Mitsuaki TAKEMI, Istituto Italiano di Tecnologia RBCS Seminar, 2014/02
  18. Is event-related desynchronization a biomarker representing corticospinal excitability?, Takemi M; Masakado Y; Liu M; Ushiba J, 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2013/07

Awards

  1. 2018/09, Top reviewers in Neuroscience and Behavior, Publons
  2. 2018/05, Travel Award, The Carolina Neurostimulation Conference
  3. 2014/06, First-class scholarship with half exemption from refund, JASSO
  4. 2013/04, Atsushi Tamura memorial scholarship, Keio University Graduate School of Science and Technology
  5. 2012/10, Annual BCI research award 2012 top 10 nominees

Patented

  1. JP7589912, 2024/11/18
  2. JP7229469, 2023/02/17
  3. JP6593838, 2019/10/04, Threshold estimation apparatus, threshold estimation method, and non-transitory computer-readable information recording medium

External Funds

Acceptance Results of Competitive Funds

  1. 2025/04/01, 2028/03/31
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  2. Grants-in-Aid for Scientific Research, Enhancement of sensory-motor function by somatosensory evoked potential neurofeedback, 2024/04/01, 2027/03/31
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  3. Moonshot R&D, Liberation from Biological Limitations via Physical, Cognitive and Perceptual Augmentation (PM: Ryota Kanai) "Development of social platform for trusted brain-machine interface", 2022/08, 2025/11
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  4. Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Development of a Motor Learning Support System Based on Physical Condition, 2022/04, 2024/03
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  5. Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Functional significance of successive failures in motor learning processes, 2020/04, 2022/03
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  6. PRESTO "The Future of Humans and Interactions", Towards strengthen human memories by artificially manipulating brain states, 2018/10, 2022/03
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  7. Research Funding for Longevity Sciences, A Study on Evaluation and Intervention of MCI and FLAIR elderlies based on gait analysis, 2018/04, 2019/03
  8. Grant-in-Aid for JSPS Fellows, Unraveling optimal motor learning protocol by the modulation of the learning process, 2016/04, 2019/03
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  9. Grant-in-Aid for JSPS Fellows (DC2), Development of less-invasive artificial cortico-cortical connection inducing motor plasticity, 2014/04, 2016/03
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  10. Grants-in-Aid for Scientific Research, Development of low invasive cerebral infarction model on Common Marmoset for cell therapy and regenerative medicine., 2011, 2013
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Social Activities

History as Committee Members

  1. Councilor, 2023/06, Japan Neuroscience Society
  2. Industry-Academia Collaboration Advisory Committee WG4 Member, 2022/08, Union of Brain Science Associations in Japan
  3. Program committee, 2023/05, 2023/08, The Japanese Society for Motor Control
  4. Editorial Board Member, 2017/07, 2023/07, Clinical Neurophysiology