BINTI MOHAMAD YUSOFF FARINA

Last Updated :2025/03/04

Affiliations, Positions
Research Institute for Radiation Biology and Medicine, Assistant Professor (Special Appointment)
E-mail
drfarinamyusoffhiroshima-u.ac.jp
Self-introduction
I am interested in basic, translational and clinical studies focusing on microvascular regeneration, endothelial cell, oxidative stress and cardiovascular effects in radiation biology, vascular medicine and regenerative medicine.

Basic Information

Educational Backgrounds

  • Hiroshima University, Cardiovascular Regeneration and Medicine, Biomedical and Health Sciences, Japan, 2017, 2021

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Cardiovascular medicine

Affiliated Academic Societies

Research Activities

Academic Papers

  1. Increasing risk of osteoporotic fracture is associated with vascular dysfunction and abnormal vascular structure in both men and women, Circulation Journal, 2017
  2. Optimal target level of low-density lipoprotein cholesterol for vascular function in statin naïve individuals, Scientific Reports, 2017
  3. Endothelial function is impaired in patients receiving antihypertensive drug treatment regardless of blood pressure level: FMD-J study (Flow-Mediated Dilation Japan), Hypertension, 2017
  4. Interrelationships Among Flow-Mediated Vasodilation, Nitroglycerine-Induced Vasodilation, Baseline Brachial Artery Diameter, Hyperemic Shear Stress, and Cardiovascular Risk Factors, Journal of the American Heart Association, 2017
  5. Brachial artery diameter as a marker for cardiovascular risk assessment: FMD-J study, Atherosclerosis, 2018
  6. Chronic kidney disease is associated with vascular smooth muscle dysfunction but not with endothelial dysfunction, International Journal of Cardiology, 2018
  7. Reactive hyperemia-peripheral arterial tonometry is useful for assessment of not only endothelial function but also stenosis of the digital artery, International Journal of Cardiology, 2018
  8. Endothelial dysfunction, abnormal vascular structure and lower urinary tract symptoms in men and women, International Journal of Cardiology, 2018
  9. Endothelial Dysfunction, Increased Arterial Stiffness, and Cardiovascular Risk Prediction in Patients With Coronary Artery Disease:FMD-J (Flow-Mediated Dilation Japan) Study A, Journal of the American Heart Association, 2018
  10. New assessment of endothelial function measured by short time flow-mediated vasodilation: Comparison with conventional flow-mediated vasodilation measurement, International Journal of Cardiology, 2018
  11. Microvascular endothelial function is impaired in patients with idiopathic hyperaldosteronism, Hypertension Research, 2018
  12. Coffee with a high content of chlorogenic acids and low content of hydroxyhydroquinone improves postprandial endothelial dysfunction in patients with borderline and stage 1 hypertension, European Journal of Nutrition, 2019
  13. Target of Triglycerides as Residual Risk for Cardiovascular Events in Patients With Coronary Artery Disease - Post Hoc Analysis of the FMD-J Study A -, Circulation Journal, 2019
  14. Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study, Journal of Hypertension, 2019
  15. Review of the Long-term Effects of Autologous Bone-Marrow Mononuclear Cell Implantation on Clinical Outcomes in Patients with Critical Limb Ischemia, Scientific Reports, 2019
  16. Effects of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin on Blood Pressure in Hypertensive Patients with Type 2 Diabetes Mellitus, American Journal of Hypertension, 2019
  17. Relationships Between Calcium Channel Blockers and Vascular Function Tests, American Journal of Hypertension, 2019
  18. Association of extremely high levels of high-density lipoprotein cholesterol with endothelial dysfunction in men, Journal of Clinical Lipidology, 2019
  19. Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study, Scientific Reports, 2019
  20. Relationship between home blood pressure and vascular function in patients receiving antihypertensive drug treatment, Hypertension Research, 2019
  21. Hematocrit, hemoglobin and red blood cells are associated with vascular function and vascular structure in men, Scientific Reports, 2020
  22. Volume Elastic Modulus, Vascular Function, and Vascular Structure in Patients with Cardiovascular Risk Factors, Journal of Atherosclerosis, 2020
  23. Diagnostic Criteria of Flow-Mediated Vasodilation for Normal Endothelial Function and Nitroglycerin-Induced Vasodilation for Normal Vascular Smooth Muscle Function of the Brachial Artery, Journal of the American Association, 2020
  24. Long-Term Clinical Outcomes of Autologous Bone Marrow Mononuclear Cell Implantation in Patients With Severe Thromboangiitis Obliterans, Circulation Journal, 2020
  25. Relationship between high-density lipoprotein cholesterol levels and endothelial function in women: a cross-sectional study, BMJ Open, 2020
  26. Hematocrit, hemoglobin and red blood cells are associated with vascular function and vascular structure in men, Scientific Reports, 2020
  27. Increased arterial stiffness and cardiovascular risk prediction in controlled hypertensive patients with coronary artery disease: post hoc analysis of FMD-J (Flow-mediated Dilation Japan) Study A, Hypertension Research, 2020
  28. Vascular function is further impaired in subjects aged 80 years or older, Hypertension Research, 2020
  29. Pre-impaired fasting glucose state is a risk factor for endothelial dysfunction: Flow-mediated Dilation Japan (FMD-J) study, BMJ Open Diabetes Research & Care, 2020
  30. Ionizing Irradiation Induces Vascular Damage in the Aorta of Wild-Type Mice, Cancers (MDPI), 2020
  31. A Comparison of Adrenalectomy and Eplerenone on Vascular Function in Patients with Aldosterone-producing Adenoma, Journal of Clinical Endocrinology & Metabolism, 2020
  32. Relationship between cell number and clinical outcomes of autologous bone-marrow mononuclear cell implantation in critical limb ischemia, Scientific Reports, 2020
  33. Daily Low-intensity Pulsed Ultrasound Ameliorates Renal Fibrosis and Inflammation in Experimental Hypertensive and Diabetic Nephropathy, Hypertension, 2020
  34. Low Levels of Low-Density Lipoprotein Cholesterol and Endothelial Function in Subjects without Lipid-Lowering Therapy, Journal of Clinical Medicine (MDPI), 2020
  35. Endothelial function is preserved in light to moderate alcohol drinkers but is impaired in heavy drinkers in women: Flow-mediated Dilation Japan (FMD-J) study, PLOS ONE, 2020
  36. Smoking status and endothelial function in Japanese men, Scientific Reports, 2021
  37. Association of Body Mass Index with Endothelial Function in Asian Men, International Journal of Cardiology, 2021
  38. Bach1 plays an important role in angiogenesis through regulation of oxidative stress, Microvascular Research, 2021
  39. Lower triglyceride levels are associated with better endothelial function, Journal of Clinical Lipidology, 2021
  40. Autologous mononuclear cells from different sources are seen to improve wound healing in patients with haematological malignancies, The Malaysian journal of pathology, 2018
  41. Low-intensity pulsed ultrasound decreases major amputation in patients with critical limb ischemia: 5-year follow-up study, PLOS ONE, 16(8), 2021
    Link to Paper Search Results by DOI
  42. Volume Elastic Modulus, Vascular Function, and Vascular Structure in Patients with Cardiovascular Risk Factors, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 28(9), 963-973, 2021
    Link to Paper Search Results by DOI
  43. A body shape index is associated with endothelial dysfunction in both men and women, SCIENTIFIC REPORTS, 11(1), 20210909
    Link to Paper Search Results by DOI
  44. Regenerative medicine for radiation emergencies, JOURNAL OF RADIATION RESEARCH, 62, I21-I29, 202104
    Link to Paper Search Results by DOI
  45. Stair climbing activity and vascular function in patients with hypertension, HYPERTENSION RESEARCH, 44(10), 1274-1282, 202110
    Link to Paper Search Results by DOI
  46. Upstroke time as a marker of atherosclerosis in patients with diabetes mellitus who have a normal ankle-brachial index, JOURNAL OF DIABETES AND ITS COMPLICATIONS, 35(11), 202111
    Link to Paper Search Results by DOI

Invited Lecture, Oral Presentation, Poster Presentation

  1. Vascular function may predict cardiac function decline in HFmrEF, The 70th Annual Meeting of the Japanese College of Cardiology, 2022/09/24, Japanese, Japanese College of Cardiology, Kyoto, Japan
  2. Relationship between Body Mass Index (BMI) and vascular endothelial function, The 7th Annual Meeting of the Japanese Society for Vascular Insufficiency, 2022/04/17, Japanese, Japanese Society for Vascular Insufficiency
  3. Study on the relationship between upstroke time and cardiovascular disease in diabetic patients with normal ABI, The 7th Annual Meeting of the Japanese Society for Vascular Insufficiency, 2022/04/17, Japanese, Japanese Society for Vascular Insufficiency, Osaka, Japan
  4. Association between Upstroke Time at the Ankle and Coronary Artery Disease among Subjects with Normal Ankle-brachial Index, Tatsuya Maruhashi, Masato Kajikawa, Shinji Kishimoto, Takayuki Yamaji, Takahiro Harada, Yu Hashimoto, Farina Mohamad Yusoff, Yukiko Nakano, Yukihito Higashi, The 86th Annual Meeting of the Japanese Circulation Society, 2022/03/13, English, Online conference
  5. Relationship between a Body Shape Index and Endothelial Function: FMD-Japan Registry, Masato Kajikawa, Tatsuya Maruhashi, Shinji Kishimoto, Takayuki Yamaji, Takahiro Harada, Yu Hashimoto, Yiming Han, Farina Mohamad Yusoff, Ayumu Nakashima, Yukihito Higashi., The 86th Annual Meeting of the Japanese Circulation Society, 2022/03/13, Japanese
  6. A study on the frequency of sleep-disordered breathing in professional drivers, The 43rd Annual Meeting of the Japanese Society of Hypertension, 2021/10/17, Japanese, Japanese Society of Hypertension, Okinawa, Japan
  7. Brachial-ankle pulse wave velocity is useful for cardiovascular risk assessment in well-treated hypertensive patients with coronary heart disease, Tatsuya Maruhashi, Masato Kajikawa, Shinji Kishimoto, Takahiro Harada, Yu Hashimoto, Farina Mohamad Yusoff, Yukiko Nakano, Ayumu Nakashima, Bonpei Takase, Hirofumi Tomiyama, Akira Yamashina, Yukihito Higashi, The 29th Scientific Meeting of the International Society of Hypertension, 2022/10/14, English, International Society of Hypertension
  8. Impact of underweight, overweight, and obesity on endothelial function: FMD-Japan registry., Masato Kajikawa, Tatsuya Maruhashi, Shinji Kishimoto, Takahiro Harada, Yu Hashimoto, Aya Mizobuchi, Yiming Han, Farina Mohamad Yusoff, Ayumu Nakashima, Yukihito Higashi., The 29th Scientific Meeting of the International Society of Hypertension (ISH2022), 2022/10/16, English, International Society of Hypertension, Kyoto, Japan
  9. Sparing and enhancing effects of radiation dose protraction for aortic vascular damage in wild-type mice., Nobuyuki Hamada, Ki-ichiro Kawano, Takaharu Nomura, Kyoji Furukawa, Farina Mohamad Yusoff, Tatsuya Maruhashi, Makoto Maeda, Ayumu Nakashima, Yukihito Higashi., The 68th Annual Meeting of the Radiation Research Society., 2022/10/16, English, Radiation Research Society, Hawaii, USA.
  10. Therapeutic Angiogenesis With Implantation of Hypoxia-induced Mesenchymal Stem Cell, Vascular Scientific Sessions presented by the Society for Vascular Medicine, 2022/09/30, English, Society for Vascular Medicine, Denver, Colorado, USA
  11. Relationship between cell number and clinical outcomes of autologous bone marrow mononuclear cell implantation in critical limb ischemia, The virtual conference 19th Malaysian Society of Haematology Annual Scientific Meeting 2022, 2022/08/09, English, Malaysian Society of Haematology, Online
  12. Long-term clinical outcomes of autologous bone marrow mononuclear cell implantation in patients with severe thromboangiitis obliterans, The virtual conference 19th Malaysian Society of Haematology Annual Scientific Meeting 2022, 2022/08/09, English, Malaysian Society of Haematology, Online
  13. Bach1 plays an important role in angiogenesis through regulation of oxidative stress, The 6th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science - Risk Communication in Radiation Disaster – During Crisis and Reconstruction, 2022/02/07, English, Network-type Joint Usage/Research Center (Fukushima Medical University), Online
  14. Low-Intensity Pulsed Ultrasound (LIPUS) Decreases Major Amputation in Patients with Critical Limb Ischemia: 5-Year Follow-Up Study, Virtual SVM 2021 Scientific Sessions of the Society for Vascular Medicine, 2021/09/09, English, Society for Vascular Medicine, Online
  15. A Long-term Review of the Autologous Bone-Marrow Mononuclear Cells Implantation on Clinical Outcomes in Patients with Critical Limb Ischemia, The 83rd Annual Scientific Meeting of the Japanese Circulation Society, 2019/03/29, English, The Japanese Circulation Society, Yokohama, Japan
  16. Autologous Bone-Marrow Mononuclear Cells Implantation Reduces Major Amputation Risk in Patients with Critical Limb Ischemia: A Long-Term Outcome Review, The 82nd Annual Scientific Meeting of the Japanese Circulation Society, 2018/03/23, English, The Japanese Circulation Society, Osaka, Japan

Awards

  1. 2022/09/29, The Alan T Hirsch Travel Award, Society for Vascular Medicine, The Vascular Scientific Sessions presented by the Society for Vascular Medicine
  2. 2022/03/12, Annual Meeting of the Japanese Circulation Society Cardiology Regenerative Medicine Award Certificate, 86th Annual Meeting of the Japanese Circulation Society, Japanese Circulation Society