SHINJI YOSHINAGA

Last Updated :2025/03/03

Affiliations, Positions
Research Institute for Radiation Biology and Medicine, Professor
E-mail
syoshinagahiroshima-u.ac.jp
Other Contact Details
1-2-3, Kasumi, Minami-ku, Hiroshima, 734-8553, Japan, Japan
TEL : (+81)82-257-5852 FAX : (+81)82-256-7106
Self-introduction
My research interest is in epidemiological studies on radiation-associated health risks.

Basic Information

Major Professional Backgrounds

  • 2016/04/01, 2018/08/31, National Institutes for Quantum and Radiological Science and Technology, National Institute of Radiological Sciences, Team leader
  • 2011/04/01, 2012/04/30, National Institute of Radiological Sciences, Team Leader
  • 2012/05/01, 2013/03/31, National Institute of Radiological Sciences, Head of Special Research
  • 2013/04/01, 2015/03/31, National Institute of Radiological Sciences, Team Leader
  • 2015/04/01, 2016/03/31, National Institute of Radiological Sciences, Team Leader
  • 2000/03/27, 2001/03/26, National Cancer Institute, Radiation Epidemiology Branch, Special Volunteer
  • 2018/09/01, Hiroshima University, Research Institute for Radiation Biology and Medicine, Professor

Academic Degrees

  • The University of Tokyo
  • The University of Tokyo

Research Fields

  • Environmental science;Environmental analyses and evaluation;Risk sciences of radiation and chemicals
  • Medicine,dentistry, and pharmacy;Society medicine;Epidemiology and preventive medicine

Research Keywords

  • Radiation Effects, Radiation Epidemiology, Radiation Risk Assessment

Educational Activity

Course in Charge

  1. 2024, Graduate Education (Master's Program) , 3Term, Data Literacy in Medicine
  2. 2024, Graduate Education (Doctoral Program) , 3Term, Utilization of data Literacy in Medicine[On-Demand]
  3. 2024, Undergraduate Education, Intensive, Practice for medical research
  4. 2024, Graduate Education (Master's Program) , First Semester, Seminar
  5. 2024, Graduate Education (Master's Program) , Second Semester, Seminar
  6. 2024, Graduate Education (Master's Program) , First Semester, Research
  7. 2024, Graduate Education (Master's Program) , Second Semester, Research
  8. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar
  9. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar
  10. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research
  11. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research
  12. 2024, Graduate Education (Master's Program) , First Semester, Molecular Biology and Radiological Science
  13. 2024, Graduate Education (Master's Program) , 1Term, Environmental Health
  14. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Environmetrics and Biometrics
  15. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Environmetrics and Biometrics
  16. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Environmetrics and Biometrics
  17. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Environmetrics and Biometrics
  18. 2024, Graduate Education (Doctoral Program) , Second Semester, History of Hiroshima Restoration

Research Activities

Academic Papers

  1. Sparing and enhancing dose protraction effects for radiation damage to the aorta of wild-type mice, INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 100(1), 37-45, 20240102
  2. Thyroid cancer risk after radiation exposure in adults-systematic review and meta-analysis, JOURNAL OF RADIATION RESEARCH, 64(6), 893-903, 20231121
  3. Car-borne survey and dose assessment from external radiation exposure in Bangka Island, ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30(38), 89280-89292, 202308
  4. Effect of exposure to radiation caused by an atomic bomb on endothelial function in atomic bomb survivors, FRONTIERS IN CARDIOVASCULAR MEDICINE, 10, 20230217
  5. Oxidative Modification Status of Human Serum Albumin Caused by Chronic Low-Dose Radiation Exposure in Mamuju, Sulawesi, Indonesia, ANTIOXIDANTS, 11(12), 202212
  6. Detection of biological responses to low-dose radiation in humans, FREE RADICAL BIOLOGY AND MEDICINE, 184, 196-207, 20220501
  7. The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique, FRONTIERS IN PUBLIC HEALTH, 9, 20211129
  8. A unique high natural background radiation area - Dose assessment and perspectives, SCIENCE OF THE TOTAL ENVIRONMENT, 750, 20210101
  9. Lens opacity prevalence among the residents in high natural background radiation area in Yangjiang, China, JOURNAL OF RADIATION RESEARCH, 62(1), 67-72, 202101
  10. Conclusions and Suggestions on Low-Dose and Low-Dose Rate Radiation Risk Estimation Methodology, JOURNAL OF RADIATION PROTECTION AND RESEARCH, 46(1), 14-23, 202103
  11. The Effect and Effectiveness of Decontaminating a Pond in a Residential Area of Fukushima, HEALTH PHYSICS, 121(1), 48-57, 202107
  12. Comprehensive exposure assessments from the viewpoint of health in a unique high natural background radiation area, Mamuju, Indonesia, SCIENTIFIC REPORTS, 11(1), 20210716
  13. Conclusions and Suggestions on Low-Dose and Low-Dose Rate Radiation Risk Estimation Methodology, Journal of Radiation Protection and Research, 46(1), 14-23, 2021
  14. Prospects and status of the dosimetry system for atomic bomb survivor cohort study conducted at Research Institute for Radiation Biology and Medicine of Hiroshima University, JOURNAL OF RADIATION RESEARCH, 62, I107-I113, 202104
  15. Dose reconstruction for residents near the former Semipalatinsk nuclear test sites with a focus on the study of radiation health effects, Japanese Journal of Health Physics, 55(4), 250-256, 202012
  16. Secondary bone/soft tissue sarcoma in childhood cancer survivors: a nationwide hospital-based case-series study in Japan, Japanese Journal of Clinical Oncology, 48(9), 806-814, 20180901
  17. Secondary cancer after a childhood cancer diagnosis: viewpoints considering primary cancer, International Journal of Clinical Oncology, 20180605
  18. Populations living near the Semipalatinsk Test Site: a new cohort for assessing health effects from protracted exposures to low-to-moderate doses of radiation, Japanese Jouunal of Health Physics, 53(3), 163-168, 20181018
  19. The State Scientific Automated Medical Registry, Kazakhstan: an important resource for low-dose radiation health research, Radiation and Environmental Biophysics, 20181116
  20. Biological measures to minimize the risk of radiotherapy-associated second cancer: a research perspective, International Journal of Radiation Biology, 92(6), 289-301, 2016
  21. Secondary cancers after a childhood cancer diagnosis: a nationwide hospital-based retrospective cohort study in Japan, International Journal of Clinical Oncology, 21(3), 506-516, 2016
  22. Methodological extensions of meta-analysis with excess relative risk estimates: application to risk of second malignant neoplasms among childhood cancer survivors treated with radiotherapy, Journal of Radiation Research, 55(5), 885-901, 2014
  23. Combined exposure to X-irradiation followed by N-ethyl-N-nitrosourea treatment alters the frequency and spectrum of Ikaros point mutations in murine T-cell lymphoma, Mutation Research, 737(1-2), 43-50, 2012
  24. Genetic variants of NPAT-ATM and AURKA are associated with an early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy, International Journal of Radiation Oncology Biology Physics, 81(4), 1144-1152, 2011
  25. Effect of radon measurement methods on dose estimation, Radiation Protection Dosimetry, 145(2-3), 224-232, 2011
  26. Meta-analysis of second cancer risk after radiotherapy among childhood cancer survivors, Radiation Protection Dosimetry, 146(1-3), 263-267, 2011
  27. Nationwide survey on pediatric CT among children of public health and school nurses to examine a possibility for a follow-up study on radiation effects, Radiation Protection Dosimetry, 146(1-3), 260-262, 2011
  28. Radiation dose of workers originating from radon in the show cave of Tapolca, Hungary, Journal of Radioanalytical and Nuclear Chemistry, 279(1), 219-225, 2009
  29. A simulation study of radon and thoron discrimination problem in case-control studies, Journal of Radiation Research, 50(6), 495-506, 2009
  30. Risk of second malignant neoplasms among cildhood cancer survivors treated with radiotherapy: meta-analysis of nine epidemiological studies, Paediatric and Perinatal Epidemiology, 23(4), 370-379, 2009
  31. Pilot study on indoor radon and thoron concentration and terrestrial gamma doses in Gejiu, Yunnan province, China Occupational Medicine, 35(3), 211-213, 2008
  32. Radon in drinking water and cancer mortality: an ecological study in Japan, AIP Conference Proceedings, 1034, 429-432, 2008
  33. Influence of environmental thoron on radon measurements and related issues, AIP Conference Proceedings, 1034, 145-148, 2008
  34. Preliminary results of indoor radon/thoron concentrations and terrestrial gamma doses in Gejiu, Yunnan, China, AIP Conference Proceedings, 1034, 173-176, 2008
  35. 210Po and 210Pb inhalation dose by cigarette smoking in Gansu and Yunnan provinces, China, Japanese Journal of Health Physics, 43, 131-134, 2008
  36. High relative biologic effectiveness of carbon ion radiation on induction of rat mammary carcinoma and its lack of H-ras and Tp53 mutations, International Journal of Radiation Oncology Biology Physics, 69(1), 194-203, 2007
  37. Haplotype-based analysis of genes associated with risk of adverse skin reactions after radiotherapy in breast cancer patients, International Journal of Radiation Oncology Biology Physics, 69(3), 685-693, 2007
  38. Airborne and waterborne radon concentrations in areas with use of groundwater supplies, Journal of Radioanalytical and Nuclear Chemistry, 267(1), 85-88, 2006
  39. Japanese individual risks of radon induced lung cancer for different exposure profiles, Japanese Journal of Health Physics, 40, 285-294, 2005
  40. ★, Nonmelanoma skin cancer in relation to ionizing radiation exposure among U.S. radiologic technologists, International Journal of Cancer, 115, 828-834, 2005
  41. Dose-rate effect on transgenerational mutation frequencies in spermatogonial stem cells of the medaka fish, Radiation Research, 163, 112-114, 2005
  42. Re: Increased brain cancer risk in physicians with high radiation exposure, Radiology, 235(2), 710-711, 2005
  43. Residential radon and childhood leukemia: a meta-analysis of published studies, Proceedings of the 6th International Conference on High Levels of Natural Radiation and Radon Areas, held in Osaka, Japan, September 2004, International Congress Series, 1276, 430-431, 2005
  44. Case-control study of residential radon and childhood leukemia in Japan: results from preliminary analyses, Proceedings of the 6th International Conference on High Levels of Natural Radiation and Radon Areas, held in Osaka, Japan, September 2004, International Congress Series, 1276, 233-235, 2005
  45. Airborne and waterborne radon concentrations in houses with the use of groundwater, Proceedings of the 6th International Conference on High Levels of Natural Radiation and Radon Areas, held in Osaka, Japan, September 2004, International Congress Series, 1276, 301-302, 2005
  46. Research on potential radiation risks in areas with nuclear power plants in Japan: leukaemia and malignant lymphoma mortality between 1972 and 1997 in 100 selected municipalities, Journal of Radiological Protection, 23, 343-368, 2004
  47. Cancer incidence in the US radiologic technologists health study, 1983-1998, Cancer, 97(12), 3080-3089, 2003
  48. Genetic susceptibility to thymic lymphomas and K-ras gene mutation in mice after exposure to X-rays and N-ethyl-N-nitrosourea, International Journal of Radiation Biology, 79(6), 423-430, 2003
  49. Cancer risks among radiologists and radiologic technologists: a review of epidemiological studies, Radiology, 233, 313-321, 2001
  50. ★, Cancer mortality among radiological technologists in Japan: updated analysis of follow-up data from 1969 to 1993, Journal of Epidemiology, 9(2), 61-72, 199904
  51. Mortality survey of Japanese radiologic technologists during the period 1969-1993, Radiation Protection Dosimetry, 77, 123-128, 1998
  52. Results and problems of occupational dose reconstruction for Japanese radiological technologists, Radiation Protection Dosimetry, 77, 73-78, 1998

Publications such as books

  1. 2005/01, International classification of HRCT for occupational and environmental respiratory diseases, Chapter 4; Radiation exposure and risk assessment in HRCT, Springer-Verlag, 2005, 1, Scholarly Book, Joint work