Kozue Hamao
Last Updated :2023/06/01
- Affiliations, Positions
- Graduate School of Integrated Sciences for Life, Associate Professor
- E-mail
- kozue
hiroshima-u.ac.jp
- Self-introduction
- I am studying the regulatory mechanism of cytoskeleton. In particular, I am focusing on the regulation of microtubule stability by dynamin-2.
Basic Information
Academic Degrees
- Doctor of Science, Hiroshima University
- Master of Science, Hiroshima University
Educational Activity
- [Bachelor Degree Program] School of Science : Biological Sciences : Biology
- [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Basic Biology
- [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biomedical Science
- [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Basic Biology
- [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biomedical Science
Research Fields
- Biology;Biological Science;Functional biochemistry
Research Keywords
- dynamin
- microtubules
- cytokinesis
- contractile ring
- myosin II
Educational Activity
Course in Charge
- 2023, Liberal Arts Education Program1, 2Term, Introductory Seminar for First-Year Students
- 2023, Undergraduate Education, Second Semester, English Seminar on Biological Science
- 2023, Undergraduate Education, 2Term, Advanced Biology
- 2023, Undergraduate Education, 2Term, Cell Biology A
- 2023, Undergraduate Education, Second Semester, Seminar for Cell Biology
- 2023, Undergraduate Education, First Semester, Special Study for Graduation
- 2023, Undergraduate Education, Second Semester, Special Study for Graduation
- 2023, Undergraduate Education, Second Semester, Practice for Fundamental Biology II
- 2023, Undergraduate Education, Second Semester, Practice for Fundamental Biology IV
- 2023, Graduate Education (Doctoral Program) , Second Semester, Career Development for Life Science
- 2023, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Basic Biology
- 2023, Graduate Education (Master's Program) , 2Term, Molecular Physiology
- 2023, Graduate Education (Master's Program) , First Semester, Exercises in Basic Biology A
- 2023, Graduate Education (Master's Program) , Second Semester, Exercises in Basic Biology B
- 2023, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar A
- 2023, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar B
- 2023, Graduate Education (Master's Program) , 1Term, Advanced Technologies for Life Science
- 2023, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biomedial Science
- 2023, Graduate Education (Master's Program) , First Semester, Exercises in Biomedical Science A
- 2023, Graduate Education (Master's Program) , Second Semester, Exercises in Biomedical Science B
- 2023, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar C
- 2023, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar D
- 2023, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar E
Research Activities
Academic Papers
- 2-(4-Nitrophenyl)-1H-indolyl-3-methyl Chromophore: A Versatile Photocage that Responds to Visible-light One-photon and Near-infrared-light Two-photon Excitations, CHEMISTRY LETTERS, 51(2), 153-156, 202202
- ★, Impairment of cytokinesis by cancer-associated DAPK3 mutations, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 533(4), 1095-1101, 20201217
- ★, ZIP kinase phosphorylated and activated by Rho kinase/ROCK contributes to cytokinesis in mammalian cultured cells, EXPERIMENTAL CELL RESEARCH, 386(1), 20200101
- Phospholipase C-related catalytically inactive protein regulates cytokinesis by protecting phosphatidylinositol 4,5-bisphosphate from metabolism in the cleavage furrow, SCIENTIFIC REPORTS, 9, 20190904
- ★, Characterization of myosin II regulatory light chain isoforms in HeLa cells, CYTOSKELETON, 72(12), 609-620, 201512
- ★, Phosphorylation of myosin II regulatory light chain by ZIP kinase is responsible for cleavage furrow ingression during cell division in mammalian cultured cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 459(4), 686-691, 20150417
- Aurora B but Not Rho/MLCK Signaling Is Required for Localization of Diphosphorylated Myosin II Regulatory Light Chain to the Midzone in Cytokinesis, PLOS ONE, 8(8), 20130807
- Phosphorylation of myosin II regulatory light chain controls its accumulation, not that of actin, at the contractile ring in HeLa cells., Experimental cell research, 318(8), 915-924, 2012
- Diphosphorylated but not monophosphorylated myosin II regulatory light chain localizes to the midzone without its heavy chain during cytokinesis., Biochemical and biophysical research communications, 417(2), 20120113
- Enhancement of myosin II/actin turnover at the contractile ring induces slower furrowing in dividing HeLa cells, BIOCHEMICAL JOURNAL, 435, 569-576, 20110501
- ★, Proline-rich domain in dynamin-2 has a low microtubule-binding activity: how is this activity controlled during mitosis in HeLa cells?, JOURNAL OF BIOCHEMISTRY, 148(5), 533-538, 201011
- Direct evidence for roles of phosphorylated regulatory light chain of myosin II in furrow ingression during cytokinesis in HeLa cells, GENES TO CELLS, 14(5), 555-568, 200905
- ★, New function of the proline rich domain in dynamin-2 to negatively regulate its interaction with microtubules in mammalian cells, EXPERIMENTAL CELL RESEARCH, 315(7), 1336-1345, 20090415
- Dvl regulates endo- and exocytotic processes through binding to synaptotagmin, GENES TO CELLS, 12, 49-61, 20070112
- Traction forces of fibroblasts are regulated by the Rho-dependent kinase but not by the myosin light chain kinase, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 456(2), 224-231, 20061215
- The carboxy-terminal pleckstrin homology domain of ROCK interacts with filamin-A, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 301(4), 886-890, 2003
- Phosphorylation of myosin II regulatory light chain is necessary for migration of HeLa cells but not for localization of myosin II at the leading edge, BIOCHEMICAL JOURNAL, 370, 551-556, 2003
- Spatial localization of mono- and diphosphorylated myosin II regulatory light chain at the leading edge of motile HeLa cells, CELL STRUCTURE AND FUNCTION, 27(6), 479-486, 2002
- Characterization of Ca2+/calmodulin-dependent protein kinase I as a myosin II regulatory light chain kinase in vitro and in vivo, BIOCHEMICAL JOURNAL, 367, 335-345, 2002
- Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells, ONCOGENE, 21(38), 5852-5860, 2002
- Phosphorylation at threonine-18 in addition to phosphorylation at serine-19 on myosin-II regulatory light chain is a mitosis-specific event, CYTOMETRY, 47(3), 150-157, 2002
- HeLa ZIP kinase induces diphosphorylation of myosin II regulatory light chain and reorganization of actin filaments in nonmuscle cells, ONCOGENE, 20(57), 8175-8183, 2001
- Differential localization of non-muscle myosin II isoforms and phosphorylated regulatory light chains in human MRC-5 fibroblasts, FEBS LETTERS, 509(3), 365-369, 2001
- Activation of actin-activated MgATPase activity of myosin II by phosphorylation with MAPK-activated protein kinase-1b (RSK-2), JOURNAL OF BIOCHEMISTRY, 128(3), 435-440, 2000