TAKUMA SUGI

Last Updated :2022/11/01

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Associate Professor
Web Site
E-mail
sugithiroshima-u.ac.jp
Self-introduction
Living things exhibit clever information processing to cope with environmental changes, even at individual level. In addition, we are often fascinated with emergence of more intelligent behaviors when living things collectively self-organize at population level. Our ultimate research purpose is to understand an origin of this intelligence. Therefore, we employ the nematode C. elegans as a model animal and seek physical rules governing individual and population level behaviors and aging of its underlying neural network. For this purpose, we have taken interdisciplinary approaches between behavioral genetics, engineering and nonlinear physics.

Basic Information

Major Professional Backgrounds

  • 2003/04/01, 2004/03/31, Takeda Pharamaceutical Company, Researcher
  • 2007/04/01, 2011/03/31, Nagoya University, Postdoctoral researcher
  • 2011/04/01, 2012/09/30, Kyoto University, JSPS PD researcher
  • 2012, 2016, Kyoto University, Assistant professor
  • 2012/10/01, 2016/03/31, Japan Science and Technology Agrency, PRESTO researcher
  • 2016/08/01, 2018/03/31, Shiga University of Medical Science, Project Associate professor
  • 2018/04/01, 2020/03/31, Shiga University of Medical Science, Assistant professor
  • 2020/04/01, 2021/03/31, Hiroshima University, Graduate School of Integrated Sciences for Life, Project associate professor
  • 2021/04/01, Hiroshima University, Graduate School of Integrated Sciences for Life, Associate Professor

Educational Backgrounds

  • Kyoto University, Undergraduate school of industrial chemistry, 1997/04, 2001/03
  • Kyoto University, Department of engineering, Department of molecular engineering, 2001/04, 2003/03
  • Kyoto University, Graduate school of biostudies, 2004/04, 2007/03
  • Kyoto University, Ph.D. (Life Science), 2007/05

Academic Degrees

  • Kyoto University
  • Kyoto University

Research Fields

  • Biology;Biological Science;Biophysics
  • Biological Sciences;Neuroscience;Neurophysiology / General neuroscience
  • Biology;Basic biology;Genetics / Chromosome dynamics

Affiliated Academic Societies

  • The Biophysical Society of Japan
  • The Japan Neuroscience Society
  • The Molecular Biology Society of Japan

Educational Activity

Course in Charge

  1. 2022, Undergraduate Education, 2Term, Advanced Biology
  2. 2022, Undergraduate Education, 1Term, Basic Biological Science A
  3. 2022, Undergraduate Education, 4Term, Molecular Genetics B
  4. 2022, Undergraduate Education, First Semester, Special Study for Graduation
  5. 2022, Undergraduate Education, Second Semester, Special Study for Graduation
  6. 2022, Undergraduate Education, First Semester, Practice for Fundamental Biology I
  7. 2022, Undergraduate Education, Second Semester, Practice for Fundamental Biology IV
  8. 2022, Graduate Education (Master's Program) , 1Term, Special Lectures in Integrated Sciences for Life
  9. 2022, Graduate Education (Master's Program) , 1Term, Introduction to Life Science
  10. 2022, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar A
  11. 2022, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar B
  12. 2022, Graduate Education (Master's Program) , 1Term, Exercises in Biomedical Science A
  13. 2022, Graduate Education (Master's Program) , 2Term, Exercises in Biomedical Science A
  14. 2022, Graduate Education (Master's Program) , 3Term, Exercises in Biomedical Science B
  15. 2022, Graduate Education (Master's Program) , 4Term, Exercises in Biomedical Science B
  16. 2022, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biomedial Science
  17. 2022, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar C
  18. 2022, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar D
  19. 2022, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar E
  20. 2022, Graduate Education (Master's Program) , 2Term, Basics and Practical Applications of Genome Editing
  21. 2022, Graduate Education (Master's Program) , OutOfTerm(1st), Basic Training of Genome Editing
  22. 2022, Graduate Education (Doctoral Program) , 3Term, Trends of Genome Editing in Life Science

Research Activities

Academic Papers

  1. All-Optical Wide-Field Selective Imaging of Fluorescent Nanodiamonds in Cells, In Vivo and Ex Vivo., ACS Nano, 15(8), 12869-12879, 2021
  2. Tracking the 3D Rotational Dynamics in Nanoscopic Biological Systems., J Am Chem Soc, 142(16), 7542-7554, 2020
  3. C. elegans collectively forms dynamical networks., Nature Communications, 10(1), 683, 2019
  4. High-throughput optical quantification of mechanosensory habituation reveals neurons encoding memory in Caenorhabditis elegans., Proc Natl Acad Sci USA, 2014
  5. Identification of the AFD neuron as the site of action of the CREB protein in Caenorhabditis elegans thermotaxis, EMBO reports, 12(8), 855-862, 2011
  6. Regulation of behavioral plasticity by systemic temperature signaling in Caenorhabditis elegans., Nature Neuroscience, 14(8), 984, 2011
  7. Crystal structures of autoinhibitory PDZ domain of Tamalin: implications for metabotropic glutamate receptor trafficking regulation, EMBO Journal, 26(8), 2192-2205, 2007
  8. Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo, Nano Letters, 12(11), 5726-5732, 2012
  9. Lipid class composition of membrane and raft fractions from brains of individuals with Alzheimer's disease., Biochem Biophys Rep, 20, 10074, 2019
  10. Noninvasive Mechanochemical Imaging in Unconstrained Caenorhabditis elegans., Materials, 11(6), 2018
  11. Nanoscale Mechanical Stimulation Method for Quantifying C. elegans Mechanosensory Behavior and Memory, Analytical Sciences, 32(11), 1164, 2016
  12. Optically Detected Magnetic Resonance of Nanodiamonds In Vivo; Implementation of Selective Imaging and Fast Sampling., J Nanosci Nanotechnol, 15(2), 1014-1021, 2015
  13. Simplified method for cell-specific gene expression analysis in Caenorhabditis elegans, Biochem Biophys Res Commun, 450(1), 330-334, 2014
  14. Versatile strategy for isolating transcription activator-like effector nuclease-mediated knockout mutants in Caenorhabditis elegans, Dev Growth Differ, 56(1), 78-85
  15. Structural insights into the PIP2 recognition by syntenin-1 PDZ domain., Biochem Biophys Res Commun, 366(2), 373-378, 2008
  16. FAM3C in Alzheimer’s disease. A risk-related molecule and potential therapeutic target., The Neuroscience of Dementia, 2019
  17. Calcium imaging in freely behaving Caenorhabditis elegans with well-controlled, nonlocalized vibrations, J Vis Exp

External Funds

Acceptance Results of Competitive Funds

  1. FOREST
  2. 2018/06/29, 2023/03/31
  3. 2021/04/01, 2024/03/31
  4. Advanced Research and Development Programs for Medical Innovation, 2019/04/01, 2023/03/31