TAKUMA SUGI

Last Updated :2025/05/09

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Professor (Special Recognition)
Web Site
http://takumasugi.com/
E-mail
sugithiroshima-u.ac.jp
Self-introduction
Living things exhibit clever information processing to cope with environmental changes, even at individual level. In addition, we are often fascinated with emergence of more intelligent behaviors when living things collectively self-organize at population level. Our ultimate research purpose is to understand an origin of this intelligence. Therefore, we employ the nematode C. elegans as a model animal and seek physical rules governing individual and population level behaviors and aging of its underlying neural network. For this purpose, we have taken interdisciplinary approaches between behavioral genetics, engineering and nonlinear physics.

Basic Information

Major Professional Backgrounds

  • 2003/04/01, 2004/03/31, Takeda Pharamaceutical Company, Researcher
  • 2007/04/01, 2011/03/31, Nagoya University, Postdoctoral researcher
  • 2011/04/01, 2012/09/30, Kyoto University, JSPS PD researcher
  • 2012, 2016, Kyoto University, Assistant professor
  • 2012/10/01, 2016/03/31, Japan Science and Technology Agrency, PRESTO researcher
  • 2016/08/01, 2018/03/31, Shiga University of Medical Science, Project Associate professor
  • 2018/04/01, 2020/03/31, Shiga University of Medical Science, Assistant professor
  • 2020/04/01, 2021/03/31, Hiroshima University, Graduate School of Integrated Sciences for Life, Project associate professor
  • 2021/04/01, Hiroshima University, Graduate School of Integrated Sciences for Life, Associate Professor
  • 2023/03/23, Hiroshima University, Professor (Special Recognition)

Educational Backgrounds

  • Kyoto University, Undergraduate school of industrial chemistry, 1997/04, 2001/03
  • Kyoto University, Department of engineering, Department of molecular engineering, 2001/04, 2003/03
  • Kyoto University, Graduate school of biostudies, 2004/04, 2007/03
  • Kyoto University, Ph.D. (Life Science), 2007/05

Academic Degrees

  • Kyoto University

Research Fields

  • Biology;Biological Science;Biophysics
  • Biological Sciences;Neuroscience;Neurophysiology / General neuroscience
  • Biology;Basic biology;Genetics / Chromosome dynamics

Affiliated Academic Societies

  • The Biophysical Society of Japan
  • The Japan Neuroscience Society
  • The Molecular Biology Society of Japan

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, 2Term, Advanced Biology
  2. 2025, Undergraduate Education, 1Term, Basic Biological Science A
  3. 2025, Undergraduate Education, 4Term, Molecular Genetics B
  4. 2025, Undergraduate Education, Second Semester, Seminar for Molecular Genetics
  5. 2025, Undergraduate Education, First Semester, Practice for Fundamental Biology III
  6. 2025, Undergraduate Education, Second Semester, Practice for Fundamental Biology IV
  7. 2025, Undergraduate Education, First Semester, Practice for Fundamental Biology IV
  8. 2025, Graduate Education (Master's Program) , 1Term, Introduction to Life Science
  9. 2025, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar A
  10. 2025, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar B
  11. 2025, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar C
  12. 2025, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar D
  13. 2025, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar E
  14. 2025, Graduate Education (Master's Program) , 2Term, Basics and Practical Applications of Genome Editing
  15. 2025, Graduate Education (Master's Program) , OutOfTerm(1st), Basic Training of Genome Editing
  16. 2025, Graduate Education (Doctoral Program) , 3Term, Trends of Genome Editing in Life Science

Research Activities

Academic Papers

  1. ★, Development and application of 4D light-field and quantum imaging technologies, SPIE, 12608, 184-185, 20230920
    Link to Paper Search Results by DOI
  2. ★, Caenorhabditis elegans transfers across a gap under an electric field as dispersal behavior, Current Biology, 33(13), 2668-+, 20230710
    Link to Paper Search Results by DOI
  3. ★, Genome Editing of C. elegans, Methods Mol Biol, 2637, 389-396, 20230212
  4. ★, The Large-Scale Cultivation of Nematodes to Study Their Collective Behaviors, Journal of Visualized Experiments, 202308
    Link to Paper Search Results by DOI
  5. ★, Human FAM3C restores memory-based thermotaxis of Caenorhabditis elegans famp-1/m70.4 loss-of-function mutants, PNAS NEXUS, 1(5), 202211
    Link to Paper Search Results by DOI
  6. Controllable Biological Rhythms and Patterns, JOURNAL OF ROBOTICS AND MECHATRONICS, 34(2), 253-256, 202204
    Link to Paper Search Results by DOI
  7. ★, All-Optical Wide-Field Selective Imaging of Fluorescent Nanodiamonds in Cells, In Vivo and Ex Vivo., ACS Nano, 15(8), 12869-12879, 2021
  8. ★, Calcium imaging in freely behaving Caenorhabditis elegans with well-controlled, nonlocalized vibrations, J Vis Exp, 2021
  9. Collective pattern formations of animals in active matter physics, BIOPHYSICS AND PHYSICOBIOLOGY, 18, 254-262, 2021
    Link to Paper Search Results by DOI
  10. ★, Tracking the 3D Rotational Dynamics in Nanoscopic Biological Systems., J Am Chem Soc, 142(16), 7542-7554, 2020
    Link to Paper Search Results by DOI
  11. ★, C. elegans collectively forms dynamical networks., Nature Communications, 10(1), 683, 2019
    Link to Paper Search Results by DOI
  12. Lipid class composition of membrane and raft fractions from brains of individuals with Alzheimer's disease., Biochem Biophys Rep, 20, 10074, 2019
    Link to Paper Search Results by DOI
  13. XXX, The Neuroscience of Dementia, 2019
  14. ★, Noninvasive Mechanochemical Imaging in Unconstrained Caenorhabditis elegans., Materials, 11(6), 2018
    Link to Paper Search Results by DOI
  15. ★, Nanoscale Mechanical Stimulation Method for Quantifying C. elegans Mechanosensory Behavior and Memory, Analytical Sciences, 32(11), 1164, 2016
    Link to Paper Search Results by DOI
  16. ★, Optically Detected Magnetic Resonance of Nanodiamonds In Vivo; Implementation of Selective Imaging and Fast Sampling., J Nanosci Nanotechnol, 15(2), 1014-1021, 2015
    Link to Paper Search Results by DOI
  17. ★, High-throughput optical quantification of mechanosensory habituation reveals neurons encoding memory in Caenorhabditis elegans., Proc Natl Acad Sci USA, 2014
    Link to Paper Search Results by DOI
  18. ★, Simplified method for cell-specific gene expression analysis in Caenorhabditis elegans, Biochem Biophys Res Commun, 450(1), 330-334, 2014
    Link to Paper Search Results by DOI
  19. ★, Versatile strategy for isolating transcription activator-like effector nuclease-mediated knockout mutants in Caenorhabditis elegans, Dev Growth Differ, 56(1), 78-85, 2014
    Link to Paper Search Results by DOI
  20. ★, Real-Time Background-Free Selective Imaging of Fluorescent Nanodiamonds in Vivo, Nano Letters, 12(11), 5726-5732, 2012
    Link to Paper Search Results by DOI
  21. ★, Identification of the AFD neuron as the site of action of the CREB protein in Caenorhabditis elegans thermotaxis, EMBO reports, 12(8), 855-862, 2011
    Link to Paper Search Results by DOI
  22. ★, Regulation of behavioral plasticity by systemic temperature signaling in Caenorhabditis elegans., Nature Neuroscience, 14(8), 984, 2011
    Link to Paper Search Results by DOI
  23. ★, Structural insights into the PIP2 recognition by syntenin-1 PDZ domain., Biochem Biophys Res Commun, 366(2), 373-378, 2008
    Link to Paper Search Results by DOI
  24. ★, Crystal structures of autoinhibitory PDZ domain of Tamalin: implications for metabotropic glutamate receptor trafficking regulation, EMBO Journal, 26(8), 2192-2205, 2007
    Link to Paper Search Results by DOI

Publications such as books

  1. 2023/09/12, The Science of Soft Robots, Springer Singapore, 2023/09/12, 20230912, Scholarly Book, Joint work, 英語, Takuma Sugi, Hiroshi Ito, 978-981-19-5176-3
  2. 2022/05/24, Biotremology: Physiology, Ecology, and Evolution, Springer Cham, 2022/05/24, 20220524, Scholarly Book, Joint work, 英語

Invited Lecture, Oral Presentation, Poster Presentation

  1. Development of 4D light-field microscopy for understanding statistical physics dynamics, Ryuki Imamura, Shin Usuki, Takuma Sugi, 28th International Conference on Statistical Physics, STATPHYS28, 2023/08/07, Without Invitation, English
  2. Development and application of 4D light-field and quantum imaging technologies, Takuma Sugi, Biomedical Imaging and Sensing Conference (BISC), 2023/04/21, With Invitation, English
  3. Development of real-time 4D quantum temperature imaging system to measure intercellular thermal diffusivity, Haruka Maeoka, Ryuji Igarashi, Shin Usuki, Takuma Sugi, The 5th IFQMS, 2022/11/25, Without Invitation, English
  4. Active Matter Physics and High-speed Single-shot 4D Imaging, Takuma Sugi, The 31st International Toki Conference on Plasma and Fusion Research, 2022/11/08, With Invitation, English
  5. A new light-field microscope system for high-resolution 3D bio-imaging, Reiji Yagi, Shin Usuki, Kenjiro T. Miura, Tadatoshi Sekine, Takuma Sugi, The 9th International Conference of Asian Society for Precision Engineering and Nanotechnology (ASPEN 2022), 2022/11/04, Without Invitation, English
  6. Development of High-Resolution Light-field Microscopy for Single-shot 3D Volumetric Imaging, Ryuji Imamura, Shin Usuki, Naoya Kataoka, Takuma Sugi, 2022/09/29, Without Invitation, English
  7. Sensitive single-shot 3D temperature imaging in vivo, Haruka Maeoka, Ryuji Igarashi, Shin Usuki, Takuma Sugi, 2022/09/29, Without Invitation, English
  8. Development of Light field microscope for whole brain imaging of C. elegans, Kazuki Shigyo, Haruka Maeoka, Reiji Yagi, Kazuki Shimabukuro, Shin Usuki, Takuma Sugi, Taiwan-Japan Joint workshop, 2021/03/08, Without Invitation, English

External Funds

Acceptance Results of Competitive Funds

  1. Grant-in-Aid for Scientific Research (A), XXX, 2024/04/01, 2028/03/31
  2. Grant-in-Aid for Challenging Research (Pioneering), XX, 2023/07/01, 2027/03/31
  3. Grant-in-Aid for Transformative Research Areas (B), Creation of multi-scale 4D biology, 2023/04/01, 2026/03/31
  4. Grant-in-Aid for Transformative Research Areas (B), XX, 2023/04/01, 2026/03/31
  5. FOREST, 2023/04/01, 2026/03/31
  6. Adaptable and Seamless Technology transfer Program through targetdriven R&D(A-STEP), 2022/10/01, 2025/03/31
  7. JST-Mirai Program, 2022/10/01, 2025/03/31
  8. Science and Technology that Create New Industries, XX, 2022/04/01, 2025/03/31
  9. Grant-in-Aid for Scientific Research (C), XX, 2022/04/01, 2025/03/31
  10. Program for Creating STart-ups from Advanced Research and Technology(START), 2022//0/8/, 2023//0/3/
  11. KAKENHI(Grant-in-Aid for Scientific Research (B)), 2021/04/01, 2024/03/31
  12. Advanced Research and Development Programs for Medical Innovation, 2019/10/01, 2023/03/31
  13. 2018/06/29, 2023/03/31
  14. Basic Section 45010:Genetics-related, Understanding temporal coding of stress signaling specificity, 2018/04/01, 2021/03/31