NOBUAKI SHIME

Last Updated :2023/12/04

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medicine), Professor
E-mail
nshimehiroshima-u.ac.jp
Self-introduction
Emergency and Critical Care Medicine

Basic Information

Major Professional Backgrounds

  • 2020, Kyoto Prefectural University of Medicine, Visiting Professor
  • 2020, Doshisha University, Visiting Professor

Academic Degrees

  • Kyoto Prefectural University of Medicine

Educational Activity

  • [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
  • [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Emergency medicine

Research Keywords

  • sepsis, antibiotics, pneumonia, ECMO, ARDS

Affiliated Academic Societies

  • Japanese Society of Intensive Care Medicine
  • Japanese Association of Acute Medicine
  • Japanese Society of Infectious Disease
  • Japanese Society of Antimicrobial and Chemotherapy

Educational Activity

Course in Charge

  1. 2023, Undergraduate Education, Year, Systemic Disease Control
  2. 2023, Undergraduate Education, Intensive, Practice for medical research
  3. 2023, Undergraduate Education, Intensive, Practice of Medicine I
  4. 2023, Undergraduate Education, Intensive, Practice of Medicine II
  5. 2023, Undergraduate Education, Second Semester, Emergency and Critical Care Medicine
  6. 2023, Graduate Education (Master's Program) , 2Term, Multidisciplinary Cooperation A
  7. 2023, Graduate Education (Doctoral Program) , 2Term, Multidisciplinary Cooperation B
  8. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Emergency and Critical Care Medicine
  9. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Emergency and Critical Care Medicine
  10. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Emergency and Critical Care Medicine
  11. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Emergency and Critical Care Medicine

Research Activities

Academic Papers

  1. ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19, SCIENTIFIC DATA, 9(1), 20220730
    Link to Paper Search Results by DOI
  2. Lethal Interstitial Lung Disease Associated with a Gain-of-Function Mutation in IFIH1., J Clin Immunol, Epub ahead of print, 202305
  3. Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study., Lancet Respir Med, 11(5), 465-476, 20230121
  4. Temperature management using an intervascular cooling device for a COVID-19 patient with refractory hyperthermia., Clin Case Rep, 11(4), e7138-e7138, 20230407
  5. Impact of frailty on long-term mortality in older patients receiving intensive care via the emergency department., Sci Rep, 13(1), 5433-5433, 20230403
  6. Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19., Int J Epidemiol, 52(2), 355-376, 20230419
  7. Neurological manifestations of COVID-19 in adults and children. Brain., Brain, 146(6), 1648-1661, 20230419
  8. Efficacy of inhaled hydrogen on neurological outcome following brain ischaemia during post- cardiac arrest care (HYBRID II): a multi-centre, randomised, double-blind, placebo-controlled trial., EClinicalMedicine, 58, 101907, 20230317
  9. A study of the risk factors for phlebitis in patients stratified using the acute physiology and chronic health evaluation II score and admitted to the intensive care unit: A post hoc analysis of the AMOR-VENUS study., Front Med (Lausanne)., 9, 965706, 20221205
  10. An algorithm for PCT-guided antimicrobial therapy: a consensus statement by Japanese experts., Clin Chem Lab Med, 61(3), 407-411, 20221202
  11. Risk factors for peripheral venous catheter- related phlebitis stratified by body mass index in critically ill patients: A post-hoc analysis of the AMOR-VENUS study., Front Med (Lausanne), 9, 1037274, 20221128
  12. Unexpected cholinergic crisis caused by distigmine bromide: A case report., Medicine (Baltimore), 101(47), e31677-e31677, 20221125
  13. Trends in survival during the pandemic in patients with critical COVID-19 receiving mechanical ventilation with or without ECMO: analysis of the Japanese national registry data., Crit Care, 26(1), 354-354, 20221115
  14. Short- versus long-course antibiotic therapy for sepsis: a post hoc analysis of the nationwide cohort study., J Intensive Care, 10(1), 49-49, 20221029
  15. A burden of fluid, sodium, and chloride due to intravenous fluid therapy in patients with respiratory support: a post-hoc analysis of a multicenter cohort study., Ann Intensive Care, 12(1), 100-100, 20221022
  16. Japanese rapid/living recommendations on drug management for COVID-19: updated guidelines (July 2022)., Acute Med Surg, 9(1), e789-e789, 20221019
  17. The research environment of critical care in three Asian countries: A cross-sectional questionnaire survey., Front Med (Lausanne), 9, 975750, 20220920
  18. Controversial Efficacy of Prone-Positioning for Patients With Severe Acute Respiratory Distress Syndrome Undergoing Venous-Venous Extracorporeal Membrane Oxygenation., Crit Care Med, 50(9), e725-e726, 202209
  19. Effect of wearing a surgical mask on short-term pulmonary gas exchange in patients immediately after anaesthesia., Indian J Anaesth., 66(8), 617-619, 202208
  20. A study of the risk factors for phlebitis in patients stratified using the acute physiology and chronic health evaluation II score and admitted to the intensive care unit: A post hoc analysis of the AMOR-VENUS study, FRONTIERS IN MEDICINE, 9, 20221205
    Link to Paper Search Results by DOI
  21. Controversial Efficacy of Prone-Positioning for Patients With Severe Acute Respiratory Distress Syndrome Undergoing Venous-Venous Extracorporeal Membrane Oxygenation., Crit Care Med, 50(9), e725-e726, 20220901
  22. Purpura fulminans due to Rickettsia japonica., QJM, 115(11), 758-759, 20221114
  23. ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19., Sci Data, 9(1), 454, 20220730
  24. Alarming of Severe Respiratory Failure Requiring ECMO Caused by the SARS-CoV-2 Omicron Variant., JMA J, 5(3), 370-371, 20220715
  25. Temporal trends of medical cost and cost-effectiveness in sepsis patients: a Japanese nationwide medical claims database, JOURNAL OF INTENSIVE CARE, 10(1), 20220714
    Link to Paper Search Results by DOI
  26. ARDS Clinical Practice Guideline 2021, JOURNAL OF INTENSIVE CARE, 10(1), 20220708
    Link to Paper Search Results by DOI
  27. ARDS clinical practice guideline 2021, Respir Investig, 60(4), 446-495, 20220701
  28. Effect of region-wide use of prehospital stroke triage scale on management of patients with acute stroke, JOURNAL OF NEUROINTERVENTIONAL SURGERY, 14(7), 677-682, 20220701
    Link to Paper Search Results by DOI
  29. Neutralizing Type I Interferon Autoantibodies in Japanese Patients With Severe COVID-19., J Clin Immunol, 42(7), 1360-1370, 202210
  30. Quantification of respiratory sounds by a continuous monitoring system can be used to predict complications after extubation: a pilot study., J Clin Monit Comput, Epub ahead of print, 20220622
  31. Prediction of Prehospital Change of the Cardiac Rhythm From Nonshockable to Shockable in Out-of-Hospital Patients With Cardiac Arrest: A Post Hoc Analysis of a Nationwide, Multicenter, Prospective Registry, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 11(12), 20220621
    Link to Paper Search Results by DOI
  32. The Current and Future State of Pediatric Sepsis Definitions: An International Survey, Pediatrics, 149(6), 20220601
  33. Resource-rich Intensive Care Units Improve Health-What Is Next?, JMA J, 5(2), 285, 20220415
  34. Risk factors for peripheral intravascular catheter-related phlebitis in critically ill patients: analysis of 3429 catheters from 23 Japanese intensive care units, ANNALS OF INTENSIVE CARE, 12(1), 20220408
    Link to Paper Search Results by DOI
  35. Clinical and microbiological outcomes, by causative pathogen, in the ASPECT-NP randomized, controlled, Phase 3 trial comparing ceftolozane/tazobactam and meropenem for treatment of hospital-acquired/ventilator-associated bacterial pneumonia, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(4), 1166-1177, 20220331
    Link to Paper Search Results by DOI
  36. Short- versus prolonged-course antibiotic therapy for sepsis or infectious diseases in critically ill adults: a systematic review and meta-analysis, INFECTIOUS DISEASES, 54(3), 213-223, 20220304
    Link to Paper Search Results by DOI
  37. Regional respiratory sound abnormalities in pneumothorax and pleural effusion detected via respiratory sound visualization and quantification: case report., J Clin Monit Comput, Epub ahead of print, 20220211
  38. Real-time assessment of swallowing sound using an electronic stethoscope and an artificial intelligence system., Clin Exp Dent Res, 8(1), 225-230, 20220201
  39. Deep sedation predicts pressure injury in patients admitted to intensive care units., Nurs Crit Care, Epub ahead of print, 20220119
  40. Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study., Crit Care, 26(1), 2, 20220103
  41. Potential Confounders in Evaluating the Impact of Hyperoxia on Neurological Outcomes in Patients Receiving Extracorporeal Membrane Oxygenation., Crit Care Med, 50(1), e97-e98, 20220101
  42. Concerning the Association Between Delayed Administration of Antibiotics and Mortality in Patients With Suspected Sepsis., Crit Care Med, 50(1), e87-e88, 20220101
  43. Changes in pediatric intensive care unit cases due to the novel coronavirus., Pediatr Int, 64(1), e15019, 20220101
  44. Real-time assessment of swallowing sound using an electronic stethoscope and an artificial intelligence system, CLINICAL AND EXPERIMENTAL DENTAL RESEARCH, 8(1), 225-230, 202202
    Link to Paper Search Results by DOI
  45. A novel system that continuously visualizes and analyzes respiratory sounds to promptly evaluate upper airway abnormalities: a pilot study, JOURNAL OF CLINICAL MONITORING AND COMPUTING, 36(1), 221-226, 202202
    Link to Paper Search Results by DOI
  46. Changes in pediatric intensive care unit cases due to the novel coronavirus, PEDIATRICS INTERNATIONAL, 64(1), 202201
    Link to Paper Search Results by DOI
  47. Duration of infectious virus shedding in patients with severe coronavirus disease 2019 who required mechanical ventilation, JOURNAL OF INFECTION AND CHEMOTHERAPY, 28(1), 19-23, 202201
    Link to Paper Search Results by DOI
  48. Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort., Elife., e70970, 20211123
  49. Trends in the incidence and outcome of sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group, CRITICAL CARE, 25(1), 20210916
    Link to Paper Search Results by DOI
  50. The Association between Wearing a Mask and COVID-19, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(17), 20210901
    Link to Paper Search Results by DOI
  51. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), JOURNAL OF INTENSIVE CARE, 9(1), 20210825
    Link to Paper Search Results by DOI
  52. Patient-ventilator asynchrony, impact on clinical outcomes and effectiveness of interventions: a systematic review and meta-analysis, JOURNAL OF INTENSIVE CARE, 9(1), 20210816
    Link to Paper Search Results by DOI
  53. Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial, CRITICAL CARE, 25(1), 20210811
    Link to Paper Search Results by DOI
  54. Pharmacological and Genetic Inhibition of Translocator Protein 18 kDa Ameliorated Neuroinflammation in Murine Endotoxemia Model, SHOCK, 56(1), 142-149, 20210701
    Link to Paper Search Results by DOI
  55. Pediatric Fulminant Myocarditis in Japan: A Retrospective Nationwide Database Study of Hospital Volume, Management Practices, and Mortality, PEDIATRIC CRITICAL CARE MEDICINE, 22(7), E391-E401, 20210701
    Link to Paper Search Results by DOI
  56. Unclear Benefit of Early Tracheostomy In Patients With Coronavirus Disease 2019, Crit Care Med, 49(7), 721-722, 20210701
  57. The right care at the right place: Significance of intensive care units for critically ill patients., Lancet Reg Health West Pac, 13, 100198, 20210620
  58. Prevalence of rapid response systems in small hospitals A questionnaire survey, MEDICINE, 100(23), 20210611
    Link to Paper Search Results by DOI
  59. Frequency and Risk Factors for Reverse Triggering in Pediatric Acute Respiratory Distress Syndrome during Synchronized Intermittent Mandatory Ventilation, ANNALS OF THE AMERICAN THORACIC SOCIETY, 18(5), 820-829, 20210501
    Link to Paper Search Results by DOI
  60. Association of noninvasive respiratory support with mortality and intubation rates in acute respiratory failure: a systematic review and network meta-analysis, JOURNAL OF INTENSIVE CARE, 9(1), 20210412
    Link to Paper Search Results by DOI
  61. Post-extubation oxygenation strategies in acute respiratory failure: a systematic review and network meta-analysis, CRITICAL CARE, 25(1), 20210409
    Link to Paper Search Results by DOI
  62. Confounding Factors in a Study Investigating Mortality in Patients With Severe Hemoptysis, Crit Care Med, 49(4), 465-466, 20210401
  63. Hypothermia, Poorly Recognized by clinicians, is associated with Higher Mortality Among Critically Ill Patients with infections: A Retrospective Observational Study, JOURNAL OF INFECTION AND CHEMOTHERAPY, 27(3), 540-543, 20210301
    Link to Paper Search Results by DOI
  64. A machine-learning based approach to quantify fine crackles in the diagnosis of interstitial pneumonia A proof-of-concept study, MEDICINE, 100(7), 20210219
    Link to Paper Search Results by DOI
  65. A novel system that continuously visualizes and analyzes respiratory sounds to promptly evaluate upper airway abnormalities: a pilot study, J Clin Monit Comput, 20210118
  66. Occurrence and incidence rate of peripheral intravascular catheter-related phlebitis and complications in critically ill patients: a prospective cohort study (AMOR-VENUS study), JOURNAL OF INTENSIVE CARE, 9(1), 20210106
    Link to Paper Search Results by DOI
  67. Proteins produced by Streptococcus species in the lower respiratory tract can modify antiviral responses against influenza virus in respiratory epithelial cells, MICROBES AND INFECTION, 23(1), 20210101
    Link to Paper Search Results by DOI
  68. Japanese rapid/living recommendations on drug management for COVID-19, ACUTE MEDICINE & SURGERY, 8(1), 20210101
    Link to Paper Search Results by DOI
  69. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), Journal of Intensive Care, 8(1), 20210101
    Link to Paper Search Results by DOI
  70. The value of open-source clinical science in pandemic response: lessons from ISARIC., Lancet Infect Dis, 21(12), 1623-1624, 202112
  71. Differential Effectiveness of Hypothermic Targeted Temperature Management According to the Severity of Post-Cardiac Arrest Syndrome, JOURNAL OF CLINICAL MEDICINE, 10(23), 202112
    Link to Paper Search Results by DOI
  72. Efficacy and safety of 1.5% aqueous olanexidine gluconate antiseptic solution compared to 1% alcoholic chlorhexidine for the prevention of intravenous catheter-related infections (Apollo study): a protocol for a randomised controlled trial, BMJ OPEN, 11(12), 202112
    Link to Paper Search Results by DOI
  73. Case Report: Emphysematous Pyelonephritis With a Congenital Giant Ureterocele., Front Pediatr, 26(9), 775468, 202111
  74. Identification of Aggravation-Predicting Gene Polymorphisms in Coronavirus Disease 2019 Patients Using a Candidate Gene Approach Associated With Multiple Phase Pathogenesis: A Study in a Japanese City of 1 Million People., Crit Care Explor, 3(11), e0576-e0576, 202111
  75. Japanese rapid/living recommendations on drug management for COVID-19: updated guidelines (September 2021), Acute Med Surg, 8(1), e706-e706, 202111
  76. Did the Effect of the Guidelines eVAPorate? The Need for Improved Antimicrobial Stewardship Continues., Pediatr Crit Care Med, 22(10), 925-927, 202110
  77. COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study., Infection, 49(5), 889-905, 202110
  78. Combining pulsed xenon ultraviolet disinfection with terminal manual cleaning helps reduce the acquisition rate of methicillin-resistant Staphylococcus aureus, AMERICAN JOURNAL OF INFECTION CONTROL, 49(8), 1048-1051, 202108
    Link to Paper Search Results by DOI
  79. Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study., Intensive Care Med, 47(4), 503-520, 202104
  80. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), ACUTE MEDICINE & SURGERY, 8(1), 202101
    Link to Paper Search Results by DOI
  81. Japanese rapid/living recommendations on drug management for COVID-19: updated guidelines (September 2021), ACUTE MEDICINE & SURGERY, 8(1), 202101
    Link to Paper Search Results by DOI
  82. Early PaCO2 Changes after Initiating Extracorporeal Membrane Oxygenation: Considerations for Future Research., Am J Respir Crit Care Med, 202(11), 1600-1601, 20201201
  83. Microglial translocator protein and stressor-related disorder, NEUROCHEMISTRY INTERNATIONAL, 140, 20201101
    Link to Paper Search Results by DOI
  84. Long-Axis In-Plane Approach Versus Short-Axis Out-of-Plane Approach for Ultrasound-Guided Central Venous Catheterization in Pediatric Patients: A Randomized Controlled Trial*, PEDIATRIC CRITICAL CARE MEDICINE, 21(11), E996-E1001, 20201101
    Link to Paper Search Results by DOI
  85. Better Management of Delirium by Family Members., Crit Care Med, 48(11), 1161-1162, 20201101
  86. Microglial translocator protein and stressor-related disorder., Neurochem Int, 20201101
  87. Prolonged versus intermittent beta-lactam antibiotics intravenous infusion strategy in sepsis or septic shock patients: a systematic review with meta-analysis and trial sequential analysis of randomized trials, JOURNAL OF INTENSIVE CARE, 8(1), 20201006
    Link to Paper Search Results by DOI
  88. Early Tracheostomy in Brain Injury: More Details Are Needed for Seeking Best Practice., Crit Care Med, 48(10), 984-985, 20201001
  89. Ultrasound-guided peripheral vascular catheterization in pediatric patients: a narrative review, CRITICAL CARE, 24(1), 20200930
    Link to Paper Search Results by DOI
  90. Prognosis of pathogen-proven acute respiratory distress syndrome diagnosed from a protocol that includes bronchoalveolar lavage: a retrospective observational study, JOURNAL OF INTENSIVE CARE, 8(1), 20200723
    Link to Paper Search Results by DOI
  91. Esophageal pressure and potential confounders for evaluating patient-ventilator asynchrony., J Crit Care, 60(344), 20200701
  92. ★, Save the ICU and save lives during the COVID-19 pandemic, JOURNAL OF INTENSIVE CARE, 8(1), 20200615
    Link to Paper Search Results by DOI
  93. Further investigation of diagnostic errors in critically ill medical patients., Critical Care Medicine, 48(5), 433-434, 20200501
  94. Impact of host- and early treatment-related factors on mortality in ICU patients with candidemia: a bicentric retrospective observational study, JOURNAL OF INTENSIVE CARE, 8(1), 20200426
    Link to Paper Search Results by DOI
  95. A Ruptured Mediastinal Bronchial Artery Aneurysm Treated with Urgent Thoracic Endovascular Aortic Repair., Intern Med., 20200219
  96. Effect of pulsed xenon ultraviolet disinfection on methicillin-resistant Staphylococcus aureus contamination of high-touch surfaces in a Japanese hospital, AMERICAN JOURNAL OF INFECTION CONTROL, 48(2), 139-142, 20200201
    Link to Paper Search Results by DOI
  97. Successful treatment of extensive spinal epidural abscess with fluoroscopy-guided percutaneous drainage: a case report, JA CLINICAL REPORTS, 6(1), 20200115
    Link to Paper Search Results by DOI
  98. Successful treatment of extensive spinal epidural abscess with fluoroscopy-guided percutaneous drainage: a case report., JA Clin Rep, 6(1), 4-4, 20200115
  99. Decreased intracellular histamine concentration and basophil activation in anaphylaxis, ALLERGOLOGY INTERNATIONAL, 69(1), 78-83, 20200101
    Link to Paper Search Results by DOI
  100. Is Broad-Spectrum Antimicrobial Prophylaxis Ideal for Open-Chest Management?, Pediatr Crit Care Med., 21(3), 301-302, 202003
  101. Potential Confounders for Applying a Novel Sepsis Care Quality Improvement Program., Crit Care Med., 48(2), 161-162, 202002
  102. Dynamic Needle Tip Positioning for Ultrasound-Guided Placement of a Peripherally Inserted Central Catheter in Pediatric Patients, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 34(1), 114-118, 202001
    Link to Paper Search Results by DOI
  103. A Ruptured Mediastinal Bronchial Artery Aneurysm Treated with Urgent Thoracic Endovascular Aortic Repair, INTERNAL MEDICINE, 59(10), 1283-1286, 2020
    Link to Paper Search Results by DOI
  104. Neurally adjusted ventilatory assist mitigates ventilator-induced diaphragm injury in rabbits, RESPIRATORY RESEARCH, 20(1), 20191223
    Link to Paper Search Results by DOI
  105. Determination of the Appropriate Depth of Cuffed Endotracheal Tubes in Pediatric Intensive Care., Pediatr Crit Care Med., 20(11), 1101-1102, 20191120
  106. Unique patterns of lower respiratory tract microbiota are associated with inflammation and hospital mortality in acute respiratory distress syndrome, RESPIRATORY RESEARCH, 20(1), 20191106
    Link to Paper Search Results by DOI
  107. Early Extubation for Infant Cardiac Surgery Supported by Dexmedetomidine Use., Pediatr Crit Care Med., 20(10), 989-990, 20191020
  108. Mechanical Ventilation Management during Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome An International Multicenter Prospective Cohort, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 200(8), 1002-1012, 20191015
    Link to Paper Search Results by DOI
  109. ★, ASPECT-NP: a randomised, controlled, double-blind, phase 3, noninferiority trial of ceftolozane/tazobactam versus meropenem for treatment of nosocomial pneumonia., Lancet Infectious Diseases., 20190925
  110. Confounding factors for the effect of misdiagnosis of site of infection on in-hospital mortality., Crit Care., 23(1), 294-294, 20190903
  111. Does nasal high-flow preoxygenation really reduce intubation-related adverse events?, Intensive Care Med., 20190819
  112. Comparison of video and conventional laryngoscopes for simulated difficult emergency tracheal intubations in the presence of liquids in the airway, PLOS ONE, 14(7), 20190719
    Link to Paper Search Results by DOI
  113. Decreased intracellular histamine concentration and basophil activation in anaphylaxis., Allergol International Available online, 20190624
  114. Superiority of Dynamic Needle Tip Positioning for Ultrasound-Guided Peripheral Venous Catheterization in Patients Younger Than 2 Years Old: A Randomized Controlled Trial., Pediatr Crit Care Med., 20190618
  115. Is lung ultrasonography really useful for diagnosing weaning-induced pulmonary oedema?, Intensive Care Med., 20190606
  116. Combined Approach Versus 2 Conventional Approaches in Ultrasound-Guided Central Venous Catheterization: A Randomized Controlled Trial., J Cardiothorac Vasc Anesth., 20190528
  117. Dynamic Needle Tip Positioning for Ultrasound-Guided Placement of a Peripherally Inserted Central Catheter in Pediatric Patients., J Cardiothorac Vasc Anesth., 20190502
  118. ICU staffing models and patient outcomes., J Intensive Care., 7, 24-24, 20190424
  119. ★, A Therapeutic Strategy for All Pneumonia Patients: A 3-Year Prospective Multicenter Cohort Study Using Risk Factors for Multidrug-resistant Pathogens to Select Initial Empiric Therapy, CLINICAL INFECTIOUS DISEASES, 68(7), 1080-1088, 20190401
    Link to Paper Search Results by DOI
  120. Comparison of three video laryngoscopes and direct laryngoscopy for emergency endotracheal intubation: a retrospective cohort study., BMJ Open., 9(3), 024927-024927, 20190330
  121. Ceftolozane-tazobactam versus meropenem for treatment of nosocomial pneumonia (ASPECT-NP): a randomised, controlled, double-blind, phase 3, non-inferiority trial, LANCET INFECTIOUS DISEASES, 19(12), 1299-1311, 201912
    Link to Paper Search Results by DOI
  122. Baseline High-Resolution CT Findings Predict Acute Exacerbation of Idiopathic Pulmonary Fibrosis: German and Japanese Cohort Study, JOURNAL OF CLINICAL MEDICINE, 8(12), 201912
    Link to Paper Search Results by DOI
  123. The Volume of Pediatric Blood Culture., Pediatr Infect Dis J., 38(12), 340-341, 201912
  124. Combined Approach Versus 2 Conventional Approaches in Ultrasound-Guided Central Venous Catheterization: A Randomized Controlled Trial, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 33(11), 2979-2984, 201911
    Link to Paper Search Results by DOI
  125. Retrospective immunohistological study of autopsied lungs in patients with acute exacerbation of interstitial pneumonia managed with extracorporeal membrane oxygenation, JOURNAL OF THORACIC DISEASE, 11(11), 4436-4443, 201911
    Link to Paper Search Results by DOI
  126. Ultrasonographic Detection of Micro-Bubbles in the Right Atrium to Confirm Peripheral Venous Catheter Position in Children, CRITICAL CARE MEDICINE, 47(10), E836-E840, 201910
    Link to Paper Search Results by DOI
  127. Superiority of Dynamic Needle Tip Positioning for Ultrasound-Guided Peripheral Venous Catheterization in Patients Younger Than 2 Years Old: A Randomized Controlled Trial*, PEDIATRIC CRITICAL CARE MEDICINE, 20(9), e410-e414, 201909
    Link to Paper Search Results by DOI
  128. Dynamic Needle Tip Positioning for Ultrasound Guided Arterial Catheterization in Infants and Small Children With Deep Arteries: A Randomized Controlled Trial, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 33(7), 1919-1925, 201907
    Link to Paper Search Results by DOI
  129. Dynamic Needle Tip Positioning for Ultrasound-Guided Arterial Catheterization in Infants and Small Children With Deep Arteries: A Randomized Controlled Trial., J Cardiothorac Vasc Anesth., 33(7), 1919-1925, 201907
  130. Comparison of three video laryngoscopes and direct laryngoscopy for emergency endotracheal intubation: a retrospective cohort study, BMJ OPEN, 9(3), 201906
    Link to Paper Search Results by DOI
  131. Impact of inappropriate empiric antimicrobial therapy on mortality in pediatric patients with bloodstream infection: a retrospective observational study., J Chemother., 30, 1-6, 201905
  132. Comparing Combined Short-Axis and Long-Axis Ultrasound-Guided Central Venous Catheterization update, With Conventional Short-Axis Out-of-Plane Approaches, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 33(4), 1029-1034, 201904
    Link to Paper Search Results by DOI
  133. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study, LANCET RESPIRATORY MEDICINE, 7(2), 115-128, 201902
    Link to Paper Search Results by DOI
  134. Potential confounders for the effect of high-flow nasal cannula oxygen therapy., Crit Care., 23(1), 17-17, 201901
  135. High serum potassium level is associated with successful electrical cardioversion for new-onset atrial fibrillation in the intensive care unit: A retrospective observational study., Anaesth Intensive Care., 47(1), 52-59, 201901
  136. High serum potassium level is associated with successful electrical cardioversion for new-onset atrial fibrillation in the intensive care unit: A retrospective observational study, ANAESTHESIA AND INTENSIVE CARE, 47(1), 52-59, 201901
    Link to Paper Search Results by DOI
  137. Impact of inappropriate empiric antimicrobial therapy on mortality in pediatric patients with bloodstream infection: a retrospective observational study, JOURNAL OF CHEMOTHERAPY, 31(7-8), 388-393, 2019
    Link to Paper Search Results by DOI
  138. Clinical and microbiologic outcomes by causative pathogen in the ASPECT-NP randomized, controlled, phase 3 trial evaluating ceftolozane/tazobactam for treatment of ventilated nosocomial pneumonia., Journal of Antimicrobial Chemotherapy., 2019
  139. The western Japan chaotic rainstorm disaster: a brief report from Hiroshima., J Intensive Care., 6, 82-82, 20181217
  140. Should We Abandon Airway Pressure Release Ventilation in Pediatric Acute Respiratory Distress Syndrome?, Am J Respir Crit Care Med, 198(11), 1459-1460, 20181201
  141. Conducting trials on corticosteroid dosing for respiratory failure in the last paradise., J Intensive Care., 6, 76-76, 20181120
  142. Comparison of extracorporeal membrane oxygenation outcome for influenza-associated acute respiratory failure in Japan between 2009 and 2016, JOURNAL OF INTENSIVE CARE, 6, 20180711
    Link to Paper Search Results by DOI
  143. Regional negative pressure pulmonary edema with pulmonary thromboembolism., Internal Medicine, 57(12), 1805-1806, 20180615
  144. Successful anesthetic management during abdominal wall-lifting laparoscopic cholecystectomy in a patient with hereditary angioedema, JA CLINICAL REPORTS, 4, 20180509
    Link to Paper Search Results by DOI
  145. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), JOURNAL OF INTENSIVE CARE, 6, 20180202
    Link to Paper Search Results by DOI
  146. ★, Implementation of an empirical antimicrobial protocol in a critical care setting: A single-center retrospective observational cohort study in bacteremic patients, JOURNAL OF INFECTION AND CHEMOTHERAPY, 24(12), 965-968, 201812
    Link to Paper Search Results by DOI
  147. Rapid-onset plasma leakage of extracorporeal oxygenation membranes possibly due to hyperbilirubinemia, JOURNAL OF ARTIFICIAL ORGANS, 21(4), 475-478, 201812
    Link to Paper Search Results by DOI
  148. Ventilator-associated events: prevalence and mortality in Japan, JOURNAL OF THORACIC DISEASE, 10(12), 6942-6949, 201812
    Link to Paper Search Results by DOI
  149. Rapid-onset plasma leakage of extracorporeal oxygenation membranes possibly due to hyperbilirubinemia., J Artif Organs., 21(4), 475-478, 201812
  150. Ventilator-associated events: prevalence and mortality in Japan., J Thorac Dis., 10(12), 6942-6949, 201812
  151. Focusing on Risk Factors of Cardiac Arrest During Intubation in ICU Again., Crit Care Med., 46(11), 1082-1082, 201811
  152. A survey on infection control in emergency departments in Japan, ACUTE MEDICINE & SURGERY, 5(4), 374-379, 201810
    Link to Paper Search Results by DOI
  153. Out-of-bed mobilization of patients undergoing mechanical ventilation with orotracheal tubes: A survey study, JOURNAL OF CRITICAL CARE, 47, 173-177, 201810
    Link to Paper Search Results by DOI
  154. An outbreak of fluoroquinolone-resistant Pseudomonas aeruginosa ST357 harboring the exoU gene, JOURNAL OF INFECTION AND CHEMOTHERAPY, 24(8), 615-622, 201808
    Link to Paper Search Results by DOI
  155. Oxygen management in mechanically ventilated patients: A multicenter prospective observational study, JOURNAL OF CRITICAL CARE, 46, 1-5, 201808
    Link to Paper Search Results by DOI
  156. ★, Sera from Septic Patients Contain the Inhibiting Activity of the Extracellular ATP-Dependent Inflammasome Pathway, TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 245(3), 193-204, 201807
    Link to Paper Search Results by DOI
  157. Does Dysphagia After Extubation Really Increase Mortality?, Crit Care Med., 46(7), 726-727, 201807
  158. Committee of the Japan ECMO project. Comparison of extracorporeal membrane oxygenation outcome for influenza-associated acute respiratory failure in Japan between 2009 and 2016., J Intensive Care., 11(6), 38-38, 201807
  159. Committee for Infection Control for the Emergency Department, the Japanese Association for Acute Medicine, and the joint working group. A survey on infection control in emergency departments in Japan., Acute Med Surg., 5(4), 374-379, 201807
  160. Antimicrobials in the PICU: An Unresolved and Serious Matter., Pediatr Crit Care Med., 19(6), 581-582, 201806
  161. Pediatric sequential organ failure assessment score (pSOFA): a plea for the world-wide collaboration for consensus., Intensive Care Med., 44(6), 995-997, 201806
  162. Antimicrobials in the PICU: An Unresolved and Serious Matter., Pediatr Crit Care Med., 19(6), 581-582, 201806
  163. ★, Association between appropriate empiric antimicrobial therapy and mortality from bloodstream infections in the intensive care unit, JOURNAL OF INFECTION AND CHEMOTHERAPY, 24(4), 267-271, 201804
    Link to Paper Search Results by DOI
  164. Ultrasound-guided central venous catheter placement in children: what is a really good practice?, Intensive Care Med., 44(4), 546-547, 201804
  165. Target blood pressure for septic and vasodilatory shock: what is optimal?, Intensive Care Medicine, 44(4), 548-549, 201804
  166. Confounders for interpreting the benefit of a biomarker-based strategy in early discontinuation of empirical antifungal therapy., Intensive Care Med., 44(3), 399-400, 201803
  167. Memorable Experiencees of US Longterm Internship, Supported by Phoenix Leader Education Program., Anesthesia and Resuscitation., 53(4), 81-84, 201803
  168. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), ACUTE MEDICINE & SURGERY, 5(1), 3-89, 201801
    Link to Paper Search Results by DOI
  169. ★, Clinical outcomes after initial treatment of methicillin-resistant Staphylococcus aureus infections, INFECTION AND DRUG RESISTANCE, 11, 1073-1081, 2018
    Link to Paper Search Results by DOI
  170. Potential factors affecting lung inhomogeneity in acute respiratory distress syndrome., Intensive Care Med, 44(1), 125-126, 2018
  171. An emerging frontier in the treatment of acute exacerbation of idiopathic pulmonary fibrosis., Respir Investigation, 97-99, 2018
  172. Accurate quantification of pleural effusion and cofactors affecting weaning failure., Anesthesiology 3, 128, 678-679, 2018
  173. Is Oxygenation Really an Intrinsic Predictive Factor of Mortality in Patients Undergoing Extracorporeal Life Support?, Crit Care Med., 46(2), 181-182, 2018
  174. Comparison of the efficacy of three topical antiseptic solutions for the prevention of catheter colonization: a multicenter randomized controlled study, CRITICAL CARE, 21, 20171221
    Link to Paper Search Results by DOI
  175. Combined short- and long-axis ultrasound-guided central venous catheterization is superior to conventional techniques: A cross-over randomized controlled manikin trial, PLOS ONE, 12(12), 20171207
    Link to Paper Search Results by DOI
  176. Combined rupture of left ventricular free wall and pericardium, Intensive Care Medicine, 43(12), 1858-1859, 20171201
  177. Does enhanced antibiotic de-escalation really have no benefit in the ICU?, Critical Care, 21(1), 20171102
  178. Risk factors for sepsis-associated encephalopathy, Intensive Care Medicine, 43(10), 1548-1549, 20171001
  179. Is Higher Cerebral Oxygen Saturation Really Predictive of Favorable Neurologic Outcome after In-Hospital Cardiac Arrest?, Critical Care Medicine, 45(4), 468-469, 20170401
  180. Outcome prediction for acute respiratory distress syndrome: Are the current three variables really optimal?, Critical Care Medicine, 45(2), 237-238, 20170201
  181. Potential Confounders of the Accuracy and Reliability of Delirium Assessment Tools, Critical Care Medicine, 45(1), 114-114, 20170101
  182. The Japanese Respiratory Society Noninvasive Positive Pressure Ventilation (NPPV) Guidelines (second revised edition), Respiratory Investigation, 55(1), 83-92, 20170101
  183. New or Progressive Multiple Organ Dysfunction Syndrome in Pediatric Severe Sepsis: A Sepsis Phenotype With Higher Morbidity and Mortality, Pediatric Critical Care Medicine, 18(1), 8-16, 20170101
  184. Repetitive postoperative extubation failure and cardiac arrest due to laryngomalacia after general anesthesia in an elderly patient: a case report, JOURNAL OF ANESTHESIA, 31(5), 779-781, 201710
    Link to Paper Search Results by DOI
  185. FAM13A polymorphism as a prognostic factor in patients with idiopathic pulmonary fibrosis, RESPIRATORY MEDICINE, 123, 105-109, 2017
    Link to Paper Search Results by DOI
  186. Pneumonia Severity Assessment Tools for Predicting Mortality in Patients with Healthcare-Associated Pneumonia: A Systematic Review and Meta-Analysis, RESPIRATION, 93(6), 441-450, 2017
    Link to Paper Search Results by DOI
  187. Proposal of a New Pediatric Sequential Organ Failure Assessment Score for Possible Validation, PEDIATRIC CRITICAL CARE MEDICINE, 18(1), 98-99, 2017
  188. Next Step to Understanding Subphenotypes of Acute Respiratory Distress Syndrome, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 196(6), 795-796, 2017
  189. The role of source control in septic patients, Critical Care Medicine, 45(6), 618-619, 2017
  190. Optimal cutoff value for lung injury prediction score and potential confounders for identifying the risk of developing acute respiratory distress syndrome, Critical Care Medicine, 45(6), 624-625, 2017
  191. Successful long-term extracorporeal membrane oxygenation for invasive pulmonary aspergillosis: A case report, Journal of Medical Case Reports, 11(1), 2017
  192. Prognostic implications of aspiration pneumonia in patients with community acquired pneumonia: A systematic review with meta-analysis., Sci Rep., 6(38097), 20161207
  193. Pediatric cardiorespiratory failure successfully managed with venoarterial-venous extracorporeal membrane oxygenation: a case report, BMC PULMONARY MEDICINE, 16, 20160812
    Link to Paper Search Results by DOI
  194. ★, Early mobilization of mechanically ventilated patients in the intensive care unit, JOURNAL OF INTENSIVE CARE, 4, 20160729
    Link to Paper Search Results by DOI
  195. Potential covariates that affect post-extubation breathing effort in children., Intensive Care Med., 42(12), 2127-2128, 201612
  196. Factors affecting biomarkers of endothelial andalveolar epithelial dysfunction., Intensive Care Med., 42(12), 2111-2112, 201612
  197. Is transpulmonary pressure-guided PEEP titration really optimal?, Intensive Care Med., 42(11), 1845-1846, 201611
  198. Exploring Potential Cofactors Affecting Coagulation and Inflammation Activity During Extracorporeal Membrane Oxygenation., Crit Care Med., 44(11), e1149-e1150, 201611
  199. Successful treatment of traumatic spinal epidural haematoma with fluoroscopically-guided percutaneous drainage: a report of two cases, ANAESTHESIA AND INTENSIVE CARE, 44(6), 777-780, 201611
  200. Current rehabilitation practices in intensive care units: a preliminary survey by the Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group., J Intensive Care., 28(4), 66-66, 201610
  201. Is an Earlier and More Intensive Physical Therapy Program Better?, Am J Respir Crit Care Med., 194(8), 1032-1032, 201610
  202. Are probiotics actually useful in decreasing VAP rate?, Intensive Care Med., 42(10), 1643-1644, 201610
  203. Clinical and investigative critical care medicine in Japan., Intensive Care Med., 42(3), 453-455, 201603
  204. Emphysematous pancreatitis., Intensive Care Med., 42(6), 1075-1075, 2016
  205. Exploring Causative Pathology Is Essential for Validating Harmful Effects of Late Intubation., Crit Care Med, 44, e770-e771, 2016
  206. Prognostic implications of aspiration pneumonia in patients with community acquired pneumonia: A systematic review with meta-analysis, SCIENTIFIC REPORTS, 6, 2016
    Link to Paper Search Results by DOI
  207. Early mobilization of mechanically ventilated patients in the intensive care unit., J Intensive Care, 29(4), 50-50, 2016
  208. Clinical and investigative critical care medicine in Japan, INTENSIVE CARE MEDICINE, 42(3), 453-455, 2016
  209. Emphysematous pancreatitis, INTENSIVE CARE MEDICINE, 42(6), 1075-1075, 2016
  210. Exploring Causative Pathology Is Essential for Validating Harmful Effects of Late Intubation, CRITICAL CARE MEDICINE, 44(8), E770-E771, 2016
  211. Are probiotics actually useful in decreasing VAP rate?, INTENSIVE CARE MEDICINE, 42(10), 1643-1644, 2016
  212. Is an Earlier and More Intensive Physical Therapy Program Better?, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 194(8), 1032-1032, 2016
  213. Is transpulmonary pressure-guided PEEP titration really optimal?, INTENSIVE CARE MEDICINE, 42(11), 1845-1846, 2016
  214. Factors affecting biomarkers of endothelial and alveolar epithelial dysfunction, INTENSIVE CARE MEDICINE, 42(12), 2111-2112, 2016
  215. Potential covariates that affect post-extubation breathing effort in children, INTENSIVE CARE MEDICINE, 42(12), 2127-2128, 2016
  216. Exploring Potential Cofactors Affecting Coagulation and Inflammation Activity During Extracorporeal Membrane Oxygenation, CRITICAL CARE MEDICINE, 44(11), E1149-E1150, 2016
  217. Current rehabilitation practices in intensive care units: a preliminary survey by the Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group., J Intensive Care., 4(66), 2016
  218. Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and therapies study., Am J Respir Crit Care Med., 191(10), 1147-1157, 20150515
  219. Innovation, Cost, and Sustainability of Pediatric Ventricular Assist Device Programs., Pediatr Crit Care Med., 16(6), 589-590, 201507
  220. A survey of the competency of ambulance service personnel in the diagnosis and management of sepsis., J Emerg Med, 49(2), 147-151, 2015
  221. Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study., Crit Care., 19, 325-325, 2015
  222. Ultrasound Imaging Reduces Failure Rates of Percutaneous Central Venous Catheterization in Children., Pediatr Crit Care Med., 16(8), 718-725, 2015
  223. Polymyxin B haemoperfusion in septic shock patients., Intensive Care Med., 41(11), 2033-2033, 2015
  224. Respiratory rate criteria for pediatric systematic inlammatory response syndrome, Pediatr Crit Care Med, 15(2), 182-182, 2014
  225. A novel method for ultrasound-guided radial arterial catheterization in pediatric patients, Anesth Analg, 118(5), 1019-1026, 2014
  226. Invasive pulmonary aspergillosis in a patient presenting with idiopathic systemic capillary leak syndrome, BMJ Case Rep, 2014
  227. A pilot study of Bifidobacterium breve in neonates undergoing surgery for congenital heart disease, Journal of Intensive Care, 2(36), 2014
  228. Sepsis Registry Committee of The Japanese Society of intensive Care Medicine, Journal of Intensive Care, 2(55), 2014

Publications such as books

  1. 2016, Critical Care UPDATE, 2016, Single work, 日本語
  2. 2015, Critical Care UPDATE, 2015, Single work, 日本語
  3. 2015, Critical Care UPDATE, 2015, Single work, 日本語

Invited Lecture, Oral Presentation, Poster Presentation

  1. Save the ICU during the COVID-19 Pandemic., Shime N, The 43rd KSCCM Annual Congress ACCC2023/The 23rd Joint Scientific Congress of the KSCCM and JSICM, 2023/04/27, With Invitation, English, KSCCM, Korea
  2. Regarding the current status and problems of SSCG/JSSCG, current problems and issues of PCT insurance assessment, timing of multiple measurements., Shime N, ThermoFisher Advisory board meeting in Japan, 2022/02/08, With Invitation, English
  3. Regarding the current status and problems of SSCG/JSSCG, current problems and issues of PCT insurance assessment, timing of multiple measurements., Shime N, ThermoFisher Advisory board meeting in Japan, 2022/02/08, Without Invitation, English, ThermoFisher, WEB
  4. Emergency and ICU services of COVID-19 cases in Hiroshima University Hospital, Nobuaki SHime, Management of COVID-19 patients in Japan and Indosesia, 2020/06/04, With Invitation, English
  5. Ultrasound-guided catheter insertion in PICU, Shime N, The 7th World Congress on Pediatric Intensive and Critical Care, 2014/05/07, With Invitation, English, Istanbul
  6. Ventilator-associated events in pediatrics, Shime N, The 7th World Congress on Pediatric Intensive and Critical Care, 2014/05/07, With Invitation, English, Istanbul
  7. Comparison of three cutaneous antiseptic solutions for the prevention of catheter colonization in the adult intensive care unit : A multicenter prospective randomized controlled trial, Yasuda H, Sanui M, Komuro T, Hatakeyama J, Matsukubo S, Kawano S, Yamamoto H, Andoh K, Seo R, Shime N, The 35th international symposium on intensive and emergency medicine, 2015/03/18, With Invitation, English, Brussels
  8. Successful use of VAV ECMO in patient with respiratory failure complicated by myocarditis, M Kyo., S Ohshimo, Y Kida, T Shimatani, Y Torikoshi, K Suzuki, S Yamaga, N Hirohashi, N Shime, The 35th Annual Conference of KSCCM, 2016/04/23, Without Invitation, English
  9. Optimal Volume and Substance in Intraesophageal Balloon Catheter for Esophageal Pressure Measurement., T Shimatani, S Ohshimo, M Kyo, Y Kida, N Shime, The 35th Annual Conference of KSCCM, 2016/04/23, Without Invitation, Japanese
  10. Analysis of autopsy findings in patients with acute respiratory failure supported on V-V ECMO, Y Kida, S Ohshimo, M Kyo, T Shimatani, N Hirohashi, N Shime, The 35th Annual Conference of KSCCM, 2016/04/23, Without Invitation, Japanese
  11. Crinical Research in Japan., Shime N., Asia redional meeting in the 8th World Congress on Pedatric Intensive and Critical Care, 2016/06/05, Without Invitation, English, Tronto
  12. PREDICTORS FOR DETECTION OF DIFFICULT-TO-TREAT BACTERIA IN BILIARY TRACT INFECTION, Esaka N, Endo B, Shime N, 24th United European Gastroenterology Week, 2016/10, Without Invitation, English, Vienna
  13. Cimmunity-acquired and Healthcare-acquired pneumonia, Nobuaki Shime, Multiprofessional Critical Care Board Review Course in JAPAN 2016, 2016/11/19, With Invitation, English
  14. Utility of continuous monitoring and visualizing system for respiratory sounds., Kikutani K, Ohshimo S, Ohki S, Giga H, Yamaga S, Sadamori T, Shime N, 第46回日本集中治療医学会学術集会, 2019/03/01, Without Invitation, English, Kyoto
  15. Association between apporopriate empiric antimicrobial therapy and mortalitu from bloodstream infections in the intensive care unit., Yamaga S, Shime N, Ohshimo S., 第46回日本集中治療医学会学術集会, 2019/03/02, Without Invitation, English, Kyoto
  16. Infection control in emergency departments in Japan., Sasaki J, KudoD, Shiino Y, Ikeda H, Shime N, Yokota H, The 18th. International Congress of Emergency Medicine, 2019/04/12, Without Invitation, Japanese, The 18th. International Congress of Emergency Medicine, Seoul
  17. Infection control in emergency departments in Japan., Sasaki J, KudoD, Shiino Y, Ikeda H, Shime N, Yokota H, The 18th. International Congress of Emergency Medicine, 2019/04/12, Without Invitation, English, Seoul
  18. Survey for infection control in emergency departments in Japan., Sasaki J, KudoD, Shiino Y, Ikeda H, Shime N, Ohge H, The 29th European Congress of Clinical Microbiology and Infectious Diseases, 2019/04/13, Without Invitation, English, The 29th European Congress of Clinical Microbiology and Infectious Diseases, Amsterdam, Netherlands
  19. ASPECT-NP: a randomized, double-blind, phase III trial comparing efficacy and safety of ceftolozane/tazobactam versus meropenem in patients with ventilated nosocomial pneumonia (VNP), Kollef M, Novacek M, Kivisitk Ü, Réa-Neto Á, Shime N, Martin-Loeches I, Timsit J-F, Wunderink RG, Bruno CJ, Huntington JA, Lin K, Yu B, Butterton JR, Rhee EG., The 29th European Congress of Clinical Microbiology and Infectious Diseases, 2019/04/13, Without Invitation, English, The 29th European Congress of Clinical Microbiology and Infectious Diseases, Amsterdam, Netherlands
  20. Survey for infection control in emergency departments in Japan., Sasaki J, KudoD, Shiino Y, Ikeda H, Shime N, Ohge H., The 29th European Congress of Clinical Microbiology and Infectious Diseases, 2019/04/13, Without Invitation, English, Amsterdam, Netherlands
  21. Clinical and microbiologic outcomes by causative pathogen in the ASPECT-NP randomized, controlled, phase 3 trial evaluating ceftolozane/tazobactam for treatment of ventilated nosocomial pneumonia (VNP), Martin-Loeches I, Kivisitk Ü, Nováček M, Rea-Neto A, Timsit J-F, Shime N, Wunderink RG, Kollef M, Bruno CJ, Huntington JA, Lin G, Yu B, Butterton JR, Rhee EG, The 22nd Annual MAD-ID Meeting, 2019/05/08, Without Invitation, English, The 22nd Annual MAD-ID Meeting, Orlando,Floroda
  22. ASPECT-NP: a randomized, double-blind, phase 3 trial comparing efficacy and safety of ceftolozane/tazobactam versus meropenem in patients with ventilated nosocomial pneumonia (VNP), Kollef M, Novacek M, Kivisitk U, Rea-Neto A, Shime N, Martin-Loeches I, Timsit J-F, Wunderink R, Bruno C, Huntington J, Lin K, Yu B, Butterton JR, Rhee EG, The 22nd Annual MAD-ID Meeting, 2019/05/08, Without Invitation, English, The 22nd Annual MAD-ID Meeting, Orlando,Floroda
  23. Outcomes in patients with ventilated nosocomial pneumonia (NP) and organ failure treated with ceftolozane/tazobactam (C/T) vs meropenem (MER) - analysis of the ASPECT-NP randomized, controlled trial., Martin-Loeches I, Bruno CJ, Shime N, Wunderink RG, Kollef M, Kivistik Ü, Nováček M, Réa-Neto A, Timsit J-F, Yu B, Huntington JA, Jensen E, Butterton JR, Rhee EG, Shorr AF., ESICM (2019) European Society of Intensive Care Medicine 32nd Annual Congress., 2019/09/30, Without Invitation, English, ESICM, Berlin
  24. Ceftolozane/tazobactam (C/T) vs meropenem (MEM) in patients with ventilated hospital-acquired pneumonia (vHAP) – subset analysis of the ASPECT-NP randomized, controlled, phase 3 trial., Timsit J-F, Huntington JA, Wunderink RG, Shime N, Kollef M, Kivistik Ü, Nováček M, Réa-Neto A, Martin-Loeches I, Yu B, Bruno CJ, Jensen E, Butterton JR, Wolf DJ, Rhee EG., ESICM (2019) European Society of Intensive Care Medicine 32nd Annual Congress., 2019/09/30, Without Invitation, English, ESICM (2019) European Society of Intensive Care Medicine 32nd Annual Congress., Berlin

Awards

  1. 2022/07/03, Joint Congress Award of the 1st Joint Scientific Congress of TSCCM, TSECCM and JSICM Congress, Taiwan Society of Critical Care Medicine. Taiwan Society of Emergency and Critical Care Medicine, Chair of the Excecutive Board of the Japanese Society of Intensive Care Medicine, Prognostic analysis of patients with severe COVID-19 receiving mechanical ventilation with or without ECMO: An interim analysis of Japan national registry
  2. 2021/09/01, World congress of Anaesthesiologists 2021 BEST200, 17th World Congress of Anaesthesiologists, European Accreditation Council for Continuing Medical Educcation, Preventing bronchial intubation in children using a computer-assisted auscultation system

External Funds

Acceptance Results of Competitive Funds

  1. Research Program on Emerging and Re-emerging Infectious Diseases, 2022/04/01, 2023/03/31
  2. 2021, 2022
  3. 2011, 2014
  4. 2012, 2016
  5. 2014, 2014
  6. 2017, 2019
  7. 2017, 2019
  8. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2017, 2019
  9. 2017/.4, 2018/.3
  10. 2017/.6
  11. Development of Medical Devices and Systems for Advanced Medical Services , 2017/08/01, 2018/03/31
  12. Development of Medical Devices and Systems for Advanced Medical Services , 2018/04/01, 2019/03/31
  13. Development of Medical Devices and Systems for Advanced Medical Services, Development of Medical Devices and Systems for Advanced Medical Services, 2019, 2019
  14. 2019, 2020
  15. Acceleration Transformative Research for Medical Innovation, 2019/04/01, 2020/03/31
  16. 2020, 2020
  17. KAKENHI(Grant-in-Aid for Scientific Research (B)), 2020, 2023
  18. Acceleration Transformative Research for Medical Innovation, 2020/04/01, 2021/09/30
  19. 2020, 2021
  20. Development of Medical Devices and Systems for Advanced Medical Services, Development of Medical Devices and Systems for Advanced Medical Services, 2020, 2020

Social Activities

Organizing Academic Conferences, etc.

  1. 2023/03, 2023/03
  2. INTERNATIONAL SERIAL VIRTUAL WEBINAR MANAGEMENT OF COVID-19 PATIENTS IN JAPAN AND VIETNAM, Chair, 2021/11, 2021/11
  3. 2020/12, 2020/12
  4. 2018/12, 2018/12
  5. 2018/05, 2018/05
  6. 2018/10, 2018/10
  7. 2017/06, 2017/06
  8. 2016/06, 2016/06
  9. 2017/05, 2017/05
  10. 2016/09, 2016/09

Other Social Contributions

  1. ECMO simulation labo., ECMO simulation labo., NPO ECMO JAPAN, 2019/08/31, 2019/09/01, Planner, Seminar or workshop, Scientific organization
  2. ECMO simulation labo., ECMO simulation labo., NPO ECMO JAPAN, 2017/05/27, 2017/05/28, Planner, Seminar or workshop, Scientific organization
  3. PALS provider course, PALS provider course, JIPICC, 2019/08/17, 2019/08/18, Planner, Seminar or workshop, Scientific organization

History as Peer Reviews of Academic Papers

  1. 2022, J of Pediatric Nursing, Others, 1
  2. 2022, HELYON, Others, 1
  3. 2022, Internal Medicine, 1
  4. 2022, Medical Communication, Others, 1
  5. 2022, J of Pediatric Intensive Care, Others, 1
  6. 2021, British Journal of Anaesthesia, Others, 1
  7. 2021, Journal of Pediatric Intensive Care, Others, 1
  8. 2021, The Journal of Medical Investigation, Others, 1
  9. 2021, J of Perinatoloigy, Others, 1
  10. 2021, Frontiers in Medicine, Others, 1
  11. 2021, Clinical Infectious Disease, Others, 1
  12. 2021, BMJ case reports, Others, 2
  13. 2021, Japanese Medical Association Journal, Others, 1
  14. 2021, Scandinavian J of Trauma and Resuscitation, Others, 1
  15. 2021, J of Thoracic Disease, Others, 1
  16. 2020, International Journal of Infectious Diseases, 1
  17. 2020, Acute Medicine & Surgery, 4
  18. 2020, BMJ open, 2
  19. 2020, Cardiovascular Diagnosis and Therapy, 1
  20. 2020, Journal of International Medical Research, Others, 1
  21. 2020, Journal of Japanese Association for Acute Medicine, 4
  22. Journal of Japanese Society of Emergency Pediatrics, 2
  23. 2020, J of Artificial Organs, 2
  24. Liver International, 1
  25. 2020, Pediatrics International, 1
  26. 2020, Respiratory Medicine Case Reports, 4
  27. 2020, The Lancet Regional health western pacific, 1
  28. 2020, J Clinical Microbiology, Others, 1
  29. 2020, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2
  30. 2020, J of Infection and Chemotherapy, 6
  31. 2020, Pediatric Critical Care Medicine, Editor, Associate Editor, 14
  32. 2020, J Intensive Care, Editor, 14
  33. 2019, Infect Drug Resist, 3
  34. Pros One, Others, 1
  35. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Others, 1
  36. 2019, Clinical Interventions in Aging, Others, 1
  37. 2019, Pedaitr Crit Care Med, Editor, 11
  38. 2019, J Intensive care, Editor, 5
  39. 2018, J of Artif Organs, Others, 2
  40. 2018, J Antimicrobial Chemother, 1
  41. 2018, Med Sci Monitoring, Others, 1
  42. 2018, Int J Infect Dis, Others, 1
  43. 2018, Clinical epidemiology, Others, 1
  44. 2018, BMC pediatrics, Others, 1
  45. 2018, J Infect Chemother, Others, 4
  46. 2018, Pediatr Crit Care Med, Editor, 11
  47. 2018, J intensive care, Others, Deputy Editor, 15
  48. 2017, Acute Medicine and Surgery, Others, 1
  49. 2017, BMC pediatrics, Others, 1
  50. 2017, European Respiratory Reviews, Others, 1
  51. 2017, BMC Anesthesiology, Others, 1
  52. 2017, J Artif Organs, Others, 1
  53. 2017, Pulsus Journals, Others, 1
  54. 2017, Geriatrics Gentontology, Others, 1
  55. 2017, J Antimicrobial Chemother, Others, 1
  56. 2017, J of Infection and Chemotherapy, Others, 2
  57. 2017, J of Anesthesia, Others, 5
  58. 2017, Pediatr Crit Care Med, Editor, 16
  59. 2017, Pediatrics International, Editor, 9
  60. 2017, Journal of Intensive Care, Editor, 4
  61. 2016, Internal Medicine, Others, 1
  62. 2016, Journal of Cirtical Care, Others, 1
  63. 2016, Hospital practice, Others, 1
  64. 2016, Respiratory Medicine Case Reports, Others, 1
  65. 2016, BMC Anesthesiology, Others, 1
  66. 2016, Journal of Anesthesia, Others, 3
  67. 2016, Pediatrics international, Editor, 10
  68. 2016, Journal of Infection and Chemotherapy, Editor, 2
  69. 2016, Pediatric Critical Care Medicine, Editor, 12
  70. 2016, Journal of Intensive Care, Editor, 6
  71. 2015, Circulation Journal, Others, Reviewer, 1
  72. 2015, Hospital Practice, Others, Reviewer, 1
  73. 2015, Journal of Infection and Chemotherapy, Reviewer, 4
  74. 2015, Journal of Anesthesia, Editor, Reviewer, 4
  75. 2015, Journal of Japanese Society of Intensive Care Medicine, Others, Reviewer, 2
  76. 2015, Journal of Japanese Sciety of Surgical Infection, Editor, Editor, 4
  77. 2015, Journal of Intensive Care, Editor, Reviewer, 17
  78. 2015, Journal of Intensive Care, Editor, Associate Editor, 4
  79. 2015, Pediatrics International, Editor, Editor, 71
  80. 2015, Pediatric Critical Care Medicine, Editor, Associate Editor, 15
  81. 2015, Pediatrics International, Others, Reviewer, 2
  82. 2021, J Intensive Care, Editor, Deputy Editor, 141
  83. 2021, Acute Medicine & Surgery, 2
  84. 2021, J of Anesthesia, Others, 1
  85. 2021, Pediatric Critical Care Medicine, Editor, Associate Editor, 1
  86. 2021, Journal of Infection and Chemotherapy, Editor, 1
  87. 2021, BMC pediatrics, Others, 1
  88. 2021, International Journal of Infectious Diseases, Others, 3
  89. 2021, BMJ open, Others, 1
  90. 2021, Infect Drug Resist, Others, 1
  91. 2021, INTENSIVIST, Editor, 1
  92. 2022, INTENSIVIST, Editor, 2
  93. 2022, British Journal of Anaesthesia, Others, 1
  94. 2022, International Journal of Infectious Diseases, Others, 1
  95. 2022, BMC pediatrics, Others, 1
  96. 2022, Pediatric Critical Care Medicine, Editor, Associate Editor, 6
  97. 2022, J Intensive Care, Editor, Deputy Editor, 222
  98. 2022, Scandinavian J of Trauma and Resuscitation and Emergency Medicine, Others, 1