NOBUAKI SHIME

Last Updated :2022/11/02

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medicine), Professor
E-mail
nshimehiroshima-u.ac.jp
Self-introduction
Emergency and Critical Care Medicine

Basic Information

Major Professional Backgrounds

  • 2020, Kyoto Prefectural University of Medicine, Visiting Professor
  • 2020, Doshisha University, Visiting Professor

Academic Degrees

  • Kyoto Prefectural University of Medicine

Educational Activity

  • [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
  • [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Emergency medicine

Research Keywords

  • sepsis, antibiotics, pneumonia, ECMO, ARDS

Affiliated Academic Societies

  • Japanese Society of Intensive Care Medicine
  • Japanese Association of Acute Medicine
  • Japanese Society of Infectious Disease
  • Japanese Society of Antimicrobial and Chemotherapy

Educational Activity

Course in Charge

  1. 2022, Undergraduate Education, Year, Systemic Disease Control
  2. 2022, Undergraduate Education, Intensive, Practice for medical research
  3. 2022, Undergraduate Education, Intensive, Practice of Medicine I
  4. 2022, Undergraduate Education, Intensive, Practice of Medicine II
  5. 2022, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  6. 2022, Undergraduate Education, Second Semester, Emergency and Critical Care Medicine
  7. 2022, Graduate Education (Master's Program) , 2Term, Multidisciplinary Cooperation A
  8. 2022, Graduate Education (Doctoral Program) , 2Term, Multidisciplinary Cooperation B
  9. 2022, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Emergency and Critical Care Medicine
  10. 2022, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Emergency and Critical Care Medicine
  11. 2022, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Emergency and Critical Care Medicine
  12. 2022, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Emergency and Critical Care Medicine

Research Activities

Academic Papers

  1. Controversial Efficacy of Prone-Positioning for Patients With Severe Acute Respiratory Distress Syndrome Undergoing Venous-Venous Extracorporeal Membrane Oxygenation., Crit Care Med, 50(9), e725-e726, 20220901
  2. Purpura fulminans due to Rickettsia japonica., QJM, Epub ahead of print., 20220817
  3. ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19., Sci Data, 9(1), 454, 20220730
  4. Alarming of Severe Respiratory Failure Requiring ECMO Caused by the SARS-CoV-2 Omicron Variant., JMA J, 5(3), 370-371, 20220715
  5. Temporal trends of medical cost and cost-effectiveness in sepsis patients: a Japanese nationwide medical claims database, JOURNAL OF INTENSIVE CARE, 10(1), 20220714
  6. ARDS Clinical Practice Guideline 2021, JOURNAL OF INTENSIVE CARE, 10(1), 20220708
  7. ARDS clinical practice guideline 2021, Respir Investig, 60(4), 446-495, 20220701
  8. Effect of region-wide use of prehospital stroke triage scale on management of patients with acute stroke, JOURNAL OF NEUROINTERVENTIONAL SURGERY, 14(7), 677-682, 20220701
  9. Neutralizing Type I Interferon Autoantibodies in Japanese Patients With Severe COVID-19., J Clin Immunol, Res Sq [Preprint], 20220629
  10. Quantification of respiratory sounds by a continuous monitoring system can be used to predict complications after extubation: a pilot study., J Clin Monit Comput, Epub ahead of print, 20220622
  11. Prediction of Prehospital Change of the Cardiac Rhythm From Nonshockable to Shockable in Out-of-Hospital Patients With Cardiac Arrest: A Post Hoc Analysis of a Nationwide, Multicenter, Prospective Registry, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 11(12), 20220621
  12. The Current and Future State of Pediatric Sepsis Definitions: An International Survey, Pediatrics, 149(6), 20220601
  13. Resource-rich Intensive Care Units Improve Health-What Is Next?, JMA J, 5(2), 285, 20220415
  14. Risk factors for peripheral intravascular catheter-related phlebitis in critically ill patients: analysis of 3429 catheters from 23 Japanese intensive care units, ANNALS OF INTENSIVE CARE, 12(1), 20220408
  15. Clinical and microbiological outcomes, by causative pathogen, in the ASPECT-NP randomized, controlled, Phase 3 trial comparing ceftolozane/tazobactam and meropenem for treatment of hospital-acquired/ventilator-associated bacterial pneumonia, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(4), 1166-1177, 20220331
  16. Short- versus prolonged-course antibiotic therapy for sepsis or infectious diseases in critically ill adults: a systematic review and meta-analysis, INFECTIOUS DISEASES, 54(3), 213-223, 20220304
  17. Regional respiratory sound abnormalities in pneumothorax and pleural effusion detected via respiratory sound visualization and quantification: case report., J Clin Monit Comput, Epub ahead of print, 20220211
  18. Real-time assessment of swallowing sound using an electronic stethoscope and an artificial intelligence system., Clin Exp Dent Res, 8(1), 225-230, 20220201
  19. Deep sedation predicts pressure injury in patients admitted to intensive care units., Nurs Crit Care, Epub ahead of print, 20220119
  20. Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study., Crit Care, 26(1), 2, 20220103
  21. Potential Confounders in Evaluating the Impact of Hyperoxia on Neurological Outcomes in Patients Receiving Extracorporeal Membrane Oxygenation., Crit Care Med, 50(1), e97-e98, 20220101
  22. Concerning the Association Between Delayed Administration of Antibiotics and Mortality in Patients With Suspected Sepsis., Crit Care Med, 50(1), e87-e88, 20220101
  23. Duration of infectious virus shedding in patients with severe coronavirus disease 2019 who required mechanical ventilation., J Infect Chemother, 28(1), 19-23, 20220101
  24. Changes in pediatric intensive care unit cases due to the novel coronavirus., Pediatr Int, 64(1), e15019, 20220101
  25. Real-time assessment of swallowing sound using an electronic stethoscope and an artificial intelligence system, CLINICAL AND EXPERIMENTAL DENTAL RESEARCH, 8(1), 225-230, 202202
  26. A novel system that continuously visualizes and analyzes respiratory sounds to promptly evaluate upper airway abnormalities: a pilot study, JOURNAL OF CLINICAL MONITORING AND COMPUTING, 36(1), 221-226, 202202
  27. Changes in pediatric intensive care unit cases due to the novel coronavirus, PEDIATRICS INTERNATIONAL, 64(1), 202201
  28. Duration of infectious virus shedding in patients with severe coronavirus disease 2019 who required mechanical ventilation, JOURNAL OF INFECTION AND CHEMOTHERAPY, 28(1), 19-23, 202201
  29. Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort., Elife., e70970, 20211123
  30. Trends in the incidence and outcome of sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group, CRITICAL CARE, 25(1), 20210916
  31. The Association between Wearing a Mask and COVID-19, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(17), 20210901
  32. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), JOURNAL OF INTENSIVE CARE, 9(1), 20210825
  33. Patient-ventilator asynchrony, impact on clinical outcomes and effectiveness of interventions: a systematic review and meta-analysis, JOURNAL OF INTENSIVE CARE, 9(1), 20210816
  34. Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial, CRITICAL CARE, 25(1), 20210811
  35. Pharmacological and Genetic Inhibition of Translocator Protein 18 kDa Ameliorated Neuroinflammation in Murine Endotoxemia Model, SHOCK, 56(1), 142-149, 20210701
  36. Pediatric Fulminant Myocarditis in Japan: A Retrospective Nationwide Database Study of Hospital Volume, Management Practices, and Mortality, PEDIATRIC CRITICAL CARE MEDICINE, 22(7), E391-E401, 20210701
  37. Unclear Benefit of Early Tracheostomy In Patients With Coronavirus Disease 2019, Crit Care Med, 49(7), 721-722, 20210701
  38. The right care at the right place: Significance of intensive care units for critically ill patients., Lancet Reg Health West Pac, 13, 100198, 20210620
  39. Prevalence of rapid response systems in small hospitals A questionnaire survey, MEDICINE, 100(23), 20210611
  40. Frequency and Risk Factors for Reverse Triggering in Pediatric Acute Respiratory Distress Syndrome during Synchronized Intermittent Mandatory Ventilation, ANNALS OF THE AMERICAN THORACIC SOCIETY, 18(5), 820-829, 20210501
  41. Association of noninvasive respiratory support with mortality and intubation rates in acute respiratory failure: a systematic review and network meta-analysis, JOURNAL OF INTENSIVE CARE, 9(1), 20210412
  42. Post-extubation oxygenation strategies in acute respiratory failure: a systematic review and network meta-analysis, CRITICAL CARE, 25(1), 20210409
  43. Confounding Factors in a Study Investigating Mortality in Patients With Severe Hemoptysis, Crit Care Med, 49(4), 465-466, 20210401
  44. Hypothermia, Poorly Recognized by clinicians, is associated with Higher Mortality Among Critically Ill Patients with infections: A Retrospective Observational Study, JOURNAL OF INFECTION AND CHEMOTHERAPY, 27(3), 540-543, 20210301
  45. A machine-learning based approach to quantify fine crackles in the diagnosis of interstitial pneumonia A proof-of-concept study, MEDICINE, 100(7), 20210219
  46. A novel system that continuously visualizes and analyzes respiratory sounds to promptly evaluate upper airway abnormalities: a pilot study, J Clin Monit Comput, 20210118
  47. Occurrence and incidence rate of peripheral intravascular catheter-related phlebitis and complications in critically ill patients: a prospective cohort study (AMOR-VENUS study), JOURNAL OF INTENSIVE CARE, 9(1), 20210106
  48. Proteins produced by Streptococcus species in the lower respiratory tract can modify antiviral responses against influenza virus in respiratory epithelial cells, MICROBES AND INFECTION, 23(1), 20210101
  49. Japanese rapid/living recommendations on drug management for COVID-19, ACUTE MEDICINE & SURGERY, 8(1), 20210101
  50. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), Journal of Intensive Care, 8(1), 20210101
  51. The value of open-source clinical science in pandemic response: lessons from ISARIC., Lancet Infect Dis, 21(12), 1623-1624, 202112
  52. Differential Effectiveness of Hypothermic Targeted Temperature Management According to the Severity of Post-Cardiac Arrest Syndrome, JOURNAL OF CLINICAL MEDICINE, 10(23), 202112
  53. Efficacy and safety of 1.5% aqueous olanexidine gluconate antiseptic solution compared to 1% alcoholic chlorhexidine for the prevention of intravenous catheter-related infections (Apollo study): a protocol for a randomised controlled trial, BMJ OPEN, 11(12), 202112
  54. Case Report: Emphysematous Pyelonephritis With a Congenital Giant Ureterocele., Front Pediatr, 26(9), 775468, 202111
  55. Identification of Aggravation-Predicting Gene Polymorphisms in Coronavirus Disease 2019 Patients Using a Candidate Gene Approach Associated With Multiple Phase Pathogenesis: A Study in a Japanese City of 1 Million People., Crit Care Explor, 3(11), e0576-e0576, 202111
  56. Japanese rapid/living recommendations on drug management for COVID-19: updated guidelines (September 2021), Acute Med Surg, 8(1), e706-e706, 202111
  57. Did the Effect of the Guidelines eVAPorate? The Need for Improved Antimicrobial Stewardship Continues., Pediatr Crit Care Med, 22(10), 925-927, 202110
  58. COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study., Infection, 49(5), 889-905, 202110
  59. Combining pulsed xenon ultraviolet disinfection with terminal manual cleaning helps reduce the acquisition rate of methicillin-resistant Staphylococcus aureus, AMERICAN JOURNAL OF INFECTION CONTROL, 49(8), 1048-1051, 202108
  60. Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study., Intensive Care Med, 47(4), 503-520, 202104
  61. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), ACUTE MEDICINE & SURGERY, 8(1), 202101
  62. Japanese rapid/living recommendations on drug management for COVID-19: updated guidelines (September 2021), ACUTE MEDICINE & SURGERY, 8(1), 202101
  63. Early PaCO2 Changes after Initiating Extracorporeal Membrane Oxygenation: Considerations for Future Research., Am J Respir Crit Care Med, 202(11), 1600-1601, 20201201
  64. Microglial translocator protein and stressor-related disorder, NEUROCHEMISTRY INTERNATIONAL, 140, 20201101
  65. Long-Axis In-Plane Approach Versus Short-Axis Out-of-Plane Approach for Ultrasound-Guided Central Venous Catheterization in Pediatric Patients: A Randomized Controlled Trial*, PEDIATRIC CRITICAL CARE MEDICINE, 21(11), E996-E1001, 20201101
  66. Better Management of Delirium by Family Members., Crit Care Med, 48(11), 1161-1162, 20201101
  67. Microglial translocator protein and stressor-related disorder., Neurochem Int, 20201101
  68. Prolonged versus intermittent beta-lactam antibiotics intravenous infusion strategy in sepsis or septic shock patients: a systematic review with meta-analysis and trial sequential analysis of randomized trials, JOURNAL OF INTENSIVE CARE, 8(1), 20201006
  69. Early Tracheostomy in Brain Injury: More Details Are Needed for Seeking Best Practice., Crit Care Med, 48(10), 984-985, 20201001
  70. Ultrasound-guided peripheral vascular catheterization in pediatric patients: a narrative review, CRITICAL CARE, 24(1), 20200930
  71. Prognosis of pathogen-proven acute respiratory distress syndrome diagnosed from a protocol that includes bronchoalveolar lavage: a retrospective observational study, JOURNAL OF INTENSIVE CARE, 8(1), 20200723
  72. Esophageal pressure and potential confounders for evaluating patient-ventilator asynchrony., J Crit Care, 60(344), 20200701
  73. ★, Save the ICU and save lives during the COVID-19 pandemic, JOURNAL OF INTENSIVE CARE, 8(1), 20200615
  74. Further investigation of diagnostic errors in critically ill medical patients., Critical Care Medicine, 48(5), 433-434, 20200501
  75. Impact of host- and early treatment-related factors on mortality in ICU patients with candidemia: a bicentric retrospective observational study, JOURNAL OF INTENSIVE CARE, 8(1), 20200426
  76. A Ruptured Mediastinal Bronchial Artery Aneurysm Treated with Urgent Thoracic Endovascular Aortic Repair., Intern Med., 20200219
  77. Effect of pulsed xenon ultraviolet disinfection on methicillin-resistant Staphylococcus aureus contamination of high-touch surfaces in a Japanese hospital, AMERICAN JOURNAL OF INFECTION CONTROL, 48(2), 139-142, 20200201
  78. Successful treatment of extensive spinal epidural abscess with fluoroscopy-guided percutaneous drainage: a case report, JA CLINICAL REPORTS, 6(1), 20200115
  79. Successful treatment of extensive spinal epidural abscess with fluoroscopy-guided percutaneous drainage: a case report., JA Clin Rep, 6(1), 4-4, 20200115
  80. Decreased intracellular histamine concentration and basophil activation in anaphylaxis, ALLERGOLOGY INTERNATIONAL, 69(1), 78-83, 20200101
  81. Is Broad-Spectrum Antimicrobial Prophylaxis Ideal for Open-Chest Management?, Pediatr Crit Care Med., 21(3), 301-302, 202003
  82. Potential Confounders for Applying a Novel Sepsis Care Quality Improvement Program., Crit Care Med., 48(2), 161-162, 202002
  83. Dynamic Needle Tip Positioning for Ultrasound-Guided Placement of a Peripherally Inserted Central Catheter in Pediatric Patients, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 34(1), 114-118, 202001
  84. A Ruptured Mediastinal Bronchial Artery Aneurysm Treated with Urgent Thoracic Endovascular Aortic Repair, INTERNAL MEDICINE, 59(10), 1283-1286, 2020
  85. Neurally adjusted ventilatory assist mitigates ventilator-induced diaphragm injury in rabbits, RESPIRATORY RESEARCH, 20(1), 20191223
  86. Determination of the Appropriate Depth of Cuffed Endotracheal Tubes in Pediatric Intensive Care., Pediatr Crit Care Med., 20(11), 1101-1102, 20191120
  87. Unique patterns of lower respiratory tract microbiota are associated with inflammation and hospital mortality in acute respiratory distress syndrome, RESPIRATORY RESEARCH, 20(1), 20191106
  88. Early Extubation for Infant Cardiac Surgery Supported by Dexmedetomidine Use., Pediatr Crit Care Med., 20(10), 989-990, 20191020
  89. Mechanical Ventilation Management during Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome An International Multicenter Prospective Cohort, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 200(8), 1002-1012, 20191015
  90. ★, ASPECT-NP: a randomised, controlled, double-blind, phase 3, noninferiority trial of ceftolozane/tazobactam versus meropenem for treatment of nosocomial pneumonia., Lancet Infectious Diseases., 20190925
  91. Confounding factors for the effect of misdiagnosis of site of infection on in-hospital mortality., Crit Care., 23(1), 294-294, 20190903
  92. Does nasal high-flow preoxygenation really reduce intubation-related adverse events?, Intensive Care Med., 20190819
  93. Comparison of video and conventional laryngoscopes for simulated difficult emergency tracheal intubations in the presence of liquids in the airway, PLOS ONE, 14(7), 20190719
  94. Decreased intracellular histamine concentration and basophil activation in anaphylaxis., Allergol International Available online, 20190624
  95. Superiority of Dynamic Needle Tip Positioning for Ultrasound-Guided Peripheral Venous Catheterization in Patients Younger Than 2 Years Old: A Randomized Controlled Trial., Pediatr Crit Care Med., 20190618
  96. Is lung ultrasonography really useful for diagnosing weaning-induced pulmonary oedema?, Intensive Care Med., 20190606
  97. Combined Approach Versus 2 Conventional Approaches in Ultrasound-Guided Central Venous Catheterization: A Randomized Controlled Trial., J Cardiothorac Vasc Anesth., 20190528
  98. Dynamic Needle Tip Positioning for Ultrasound-Guided Placement of a Peripherally Inserted Central Catheter in Pediatric Patients., J Cardiothorac Vasc Anesth., 20190502
  99. ICU staffing models and patient outcomes., J Intensive Care., 7, 24-24, 20190424
  100. ★, A Therapeutic Strategy for All Pneumonia Patients: A 3-Year Prospective Multicenter Cohort Study Using Risk Factors for Multidrug-resistant Pathogens to Select Initial Empiric Therapy, CLINICAL INFECTIOUS DISEASES, 68(7), 1080-1088, 20190401
  101. Comparison of three video laryngoscopes and direct laryngoscopy for emergency endotracheal intubation: a retrospective cohort study., BMJ Open., 9(3), 024927-024927, 20190330
  102. Ceftolozane-tazobactam versus meropenem for treatment of nosocomial pneumonia (ASPECT-NP): a randomised, controlled, double-blind, phase 3, non-inferiority trial, LANCET INFECTIOUS DISEASES, 19(12), 1299-1311, 201912
  103. Baseline High-Resolution CT Findings Predict Acute Exacerbation of Idiopathic Pulmonary Fibrosis: German and Japanese Cohort Study, JOURNAL OF CLINICAL MEDICINE, 8(12), 201912
  104. The Volume of Pediatric Blood Culture., Pediatr Infect Dis J., 38(12), 340-341, 201912
  105. Combined Approach Versus 2 Conventional Approaches in Ultrasound-Guided Central Venous Catheterization: A Randomized Controlled Trial, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 33(11), 2979-2984, 201911
  106. Retrospective immunohistological study of autopsied lungs in patients with acute exacerbation of interstitial pneumonia managed with extracorporeal membrane oxygenation, JOURNAL OF THORACIC DISEASE, 11(11), 4436-4443, 201911
  107. Ultrasonographic Detection of Micro-Bubbles in the Right Atrium to Confirm Peripheral Venous Catheter Position in Children, CRITICAL CARE MEDICINE, 47(10), E836-E840, 201910
  108. Superiority of Dynamic Needle Tip Positioning for Ultrasound-Guided Peripheral Venous Catheterization in Patients Younger Than 2 Years Old: A Randomized Controlled Trial*, PEDIATRIC CRITICAL CARE MEDICINE, 20(9), e410-e414, 201909
  109. Dynamic Needle Tip Positioning for Ultrasound Guided Arterial Catheterization in Infants and Small Children With Deep Arteries: A Randomized Controlled Trial, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 33(7), 1919-1925, 201907
  110. Dynamic Needle Tip Positioning for Ultrasound-Guided Arterial Catheterization in Infants and Small Children With Deep Arteries: A Randomized Controlled Trial., J Cardiothorac Vasc Anesth., 33(7), 1919-1925, 201907
  111. Comparison of three video laryngoscopes and direct laryngoscopy for emergency endotracheal intubation: a retrospective cohort study, BMJ OPEN, 9(3), 201906
  112. Impact of inappropriate empiric antimicrobial therapy on mortality in pediatric patients with bloodstream infection: a retrospective observational study., J Chemother., 30, 1-6, 201905
  113. Comparing Combined Short-Axis and Long-Axis Ultrasound-Guided Central Venous Catheterization update, With Conventional Short-Axis Out-of-Plane Approaches, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 33(4), 1029-1034, 201904
  114. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study, LANCET RESPIRATORY MEDICINE, 7(2), 115-128, 201902
  115. Potential confounders for the effect of high-flow nasal cannula oxygen therapy., Crit Care., 23(1), 17-17, 201901
  116. High serum potassium level is associated with successful electrical cardioversion for new-onset atrial fibrillation in the intensive care unit: A retrospective observational study., Anaesth Intensive Care., 47(1), 52-59, 201901
  117. High serum potassium level is associated with successful electrical cardioversion for new-onset atrial fibrillation in the intensive care unit: A retrospective observational study, ANAESTHESIA AND INTENSIVE CARE, 47(1), 52-59, 201901
  118. Impact of inappropriate empiric antimicrobial therapy on mortality in pediatric patients with bloodstream infection: a retrospective observational study, JOURNAL OF CHEMOTHERAPY, 31(7-8), 388-393, 2019
  119. Clinical and microbiologic outcomes by causative pathogen in the ASPECT-NP randomized, controlled, phase 3 trial evaluating ceftolozane/tazobactam for treatment of ventilated nosocomial pneumonia., Journal of Antimicrobial Chemotherapy., 2019
  120. The western Japan chaotic rainstorm disaster: a brief report from Hiroshima., J Intensive Care., 6, 82-82, 20181217
  121. Should We Abandon Airway Pressure Release Ventilation in Pediatric Acute Respiratory Distress Syndrome?, Am J Respir Crit Care Med, 198(11), 1459-1460, 20181201
  122. Conducting trials on corticosteroid dosing for respiratory failure in the last paradise., J Intensive Care., 6, 76-76, 20181120
  123. Comparison of extracorporeal membrane oxygenation outcome for influenza-associated acute respiratory failure in Japan between 2009 and 2016, JOURNAL OF INTENSIVE CARE, 6, 20180711
  124. Regional negative pressure pulmonary edema with pulmonary thromboembolism., Internal Medicine, 57(12), 1805-1806, 20180615
  125. Successful anesthetic management during abdominal wall-lifting laparoscopic cholecystectomy in a patient with hereditary angioedema, JA CLINICAL REPORTS, 4, 20180509
  126. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), JOURNAL OF INTENSIVE CARE, 6, 20180202
  127. ★, Implementation of an empirical antimicrobial protocol in a critical care setting: A single-center retrospective observational cohort study in bacteremic patients, JOURNAL OF INFECTION AND CHEMOTHERAPY, 24(12), 965-968, 201812
  128. Rapid-onset plasma leakage of extracorporeal oxygenation membranes possibly due to hyperbilirubinemia, JOURNAL OF ARTIFICIAL ORGANS, 21(4), 475-478, 201812
  129. Ventilator-associated events: prevalence and mortality in Japan, JOURNAL OF THORACIC DISEASE, 10(12), 6942-6949, 201812
  130. Rapid-onset plasma leakage of extracorporeal oxygenation membranes possibly due to hyperbilirubinemia., J Artif Organs., 21(4), 475-478, 201812
  131. Ventilator-associated events: prevalence and mortality in Japan., J Thorac Dis., 10(12), 6942-6949, 201812
  132. Focusing on Risk Factors of Cardiac Arrest During Intubation in ICU Again., Crit Care Med., 46(11), 1082-1082, 201811
  133. A survey on infection control in emergency departments in Japan, ACUTE MEDICINE & SURGERY, 5(4), 374-379, 201810
  134. Out-of-bed mobilization of patients undergoing mechanical ventilation with orotracheal tubes: A survey study, JOURNAL OF CRITICAL CARE, 47, 173-177, 201810
  135. An outbreak of fluoroquinolone-resistant Pseudomonas aeruginosa ST357 harboring the exoU gene, JOURNAL OF INFECTION AND CHEMOTHERAPY, 24(8), 615-622, 201808
  136. Oxygen management in mechanically ventilated patients: A multicenter prospective observational study, JOURNAL OF CRITICAL CARE, 46, 1-5, 201808
  137. ★, Sera from Septic Patients Contain the Inhibiting Activity of the Extracellular ATP-Dependent Inflammasome Pathway, TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 245(3), 193-204, 201807
  138. Does Dysphagia After Extubation Really Increase Mortality?, Crit Care Med., 46(7), 726-727, 201807
  139. Committee of the Japan ECMO project. Comparison of extracorporeal membrane oxygenation outcome for influenza-associated acute respiratory failure in Japan between 2009 and 2016., J Intensive Care., 11(6), 38-38, 201807
  140. Committee for Infection Control for the Emergency Department, the Japanese Association for Acute Medicine, and the joint working group. A survey on infection control in emergency departments in Japan., Acute Med Surg., 5(4), 374-379, 201807
  141. Antimicrobials in the PICU: An Unresolved and Serious Matter., Pediatr Crit Care Med., 19(6), 581-582, 201806
  142. Pediatric sequential organ failure assessment score (pSOFA): a plea for the world-wide collaboration for consensus., Intensive Care Med., 44(6), 995-997, 201806
  143. Antimicrobials in the PICU: An Unresolved and Serious Matter., Pediatr Crit Care Med., 19(6), 581-582, 201806
  144. ★, Association between appropriate empiric antimicrobial therapy and mortality from bloodstream infections in the intensive care unit, JOURNAL OF INFECTION AND CHEMOTHERAPY, 24(4), 267-271, 201804
  145. Ultrasound-guided central venous catheter placement in children: what is a really good practice?, Intensive Care Med., 44(4), 546-547, 201804
  146. Target blood pressure for septic and vasodilatory shock: what is optimal?, Intensive Care Medicine, 44(4), 548-549, 201804
  147. Confounders for interpreting the benefit of a biomarker-based strategy in early discontinuation of empirical antifungal therapy., Intensive Care Med., 44(3), 399-400, 201803
  148. Memorable Experiencees of US Longterm Internship, Supported by Phoenix Leader Education Program., Anesthesia and Resuscitation., 53(4), 81-84, 201803
  149. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), ACUTE MEDICINE & SURGERY, 5(1), 3-89, 201801
  150. ★, Clinical outcomes after initial treatment of methicillin-resistant Staphylococcus aureus infections, INFECTION AND DRUG RESISTANCE, 11, 1073-1081, 2018
  151. Potential factors affecting lung inhomogeneity in acute respiratory distress syndrome., Intensive Care Med, 44(1), 125-126, 2018
  152. An emerging frontier in the treatment of acute exacerbation of idiopathic pulmonary fibrosis., Respir Investigation, 97-99, 2018
  153. Accurate quantification of pleural effusion and cofactors affecting weaning failure., Anesthesiology 3, 128, 678-679, 2018
  154. Is Oxygenation Really an Intrinsic Predictive Factor of Mortality in Patients Undergoing Extracorporeal Life Support?, Crit Care Med., 46(2), 181-182, 2018
  155. Comparison of the efficacy of three topical antiseptic solutions for the prevention of catheter colonization: a multicenter randomized controlled study, CRITICAL CARE, 21, 20171221
  156. Combined short- and long-axis ultrasound-guided central venous catheterization is superior to conventional techniques: A cross-over randomized controlled manikin trial, PLOS ONE, 12(12), 20171207
  157. Combined rupture of left ventricular free wall and pericardium, Intensive Care Medicine, 43(12), 1858-1859, 20171201
  158. Does enhanced antibiotic de-escalation really have no benefit in the ICU?, Critical Care, 21(1), 20171102
  159. Risk factors for sepsis-associated encephalopathy, Intensive Care Medicine, 43(10), 1548-1549, 20171001
  160. Is Higher Cerebral Oxygen Saturation Really Predictive of Favorable Neurologic Outcome after In-Hospital Cardiac Arrest?, Critical Care Medicine, 45(4), 468-469, 20170401
  161. Outcome prediction for acute respiratory distress syndrome: Are the current three variables really optimal?, Critical Care Medicine, 45(2), 237-238, 20170201
  162. Potential Confounders of the Accuracy and Reliability of Delirium Assessment Tools, Critical Care Medicine, 45(1), 114-114, 20170101
  163. The Japanese Respiratory Society Noninvasive Positive Pressure Ventilation (NPPV) Guidelines (second revised edition), Respiratory Investigation, 55(1), 83-92, 20170101
  164. New or Progressive Multiple Organ Dysfunction Syndrome in Pediatric Severe Sepsis: A Sepsis Phenotype With Higher Morbidity and Mortality, Pediatric Critical Care Medicine, 18(1), 8-16, 20170101
  165. Repetitive postoperative extubation failure and cardiac arrest due to laryngomalacia after general anesthesia in an elderly patient: a case report, JOURNAL OF ANESTHESIA, 31(5), 779-781, 201710
  166. FAM13A polymorphism as a prognostic factor in patients with idiopathic pulmonary fibrosis, RESPIRATORY MEDICINE, 123, 105-109, 2017
  167. Pneumonia Severity Assessment Tools for Predicting Mortality in Patients with Healthcare-Associated Pneumonia: A Systematic Review and Meta-Analysis, RESPIRATION, 93(6), 441-450, 2017
  168. Proposal of a New Pediatric Sequential Organ Failure Assessment Score for Possible Validation, PEDIATRIC CRITICAL CARE MEDICINE, 18(1), 98-99, 2017
  169. Next Step to Understanding Subphenotypes of Acute Respiratory Distress Syndrome, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 196(6), 795-796, 2017
  170. The role of source control in septic patients, Critical Care Medicine, 45(6), 618-619, 2017
  171. Optimal cutoff value for lung injury prediction score and potential confounders for identifying the risk of developing acute respiratory distress syndrome, Critical Care Medicine, 45(6), 624-625, 2017
  172. Successful long-term extracorporeal membrane oxygenation for invasive pulmonary aspergillosis: A case report, Journal of Medical Case Reports, 11(1), 2017
  173. Prognostic implications of aspiration pneumonia in patients with community acquired pneumonia: A systematic review with meta-analysis., Sci Rep., 6(38097), 20161207
  174. Pediatric cardiorespiratory failure successfully managed with venoarterial-venous extracorporeal membrane oxygenation: a case report, BMC PULMONARY MEDICINE, 16, 20160812
  175. ★, Early mobilization of mechanically ventilated patients in the intensive care unit, JOURNAL OF INTENSIVE CARE, 4, 20160729
  176. Potential covariates that affect post-extubation breathing effort in children., Intensive Care Med., 42(12), 2127-2128, 201612
  177. Factors affecting biomarkers of endothelial andalveolar epithelial dysfunction., Intensive Care Med., 42(12), 2111-2112, 201612
  178. Is transpulmonary pressure-guided PEEP titration really optimal?, Intensive Care Med., 42(11), 1845-1846, 201611
  179. Exploring Potential Cofactors Affecting Coagulation and Inflammation Activity During Extracorporeal Membrane Oxygenation., Crit Care Med., 44(11), e1149-e1150, 201611
  180. Successful treatment of traumatic spinal epidural haematoma with fluoroscopically-guided percutaneous drainage: a report of two cases, ANAESTHESIA AND INTENSIVE CARE, 44(6), 777-780, 201611
  181. Current rehabilitation practices in intensive care units: a preliminary survey by the Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group., J Intensive Care., 28(4), 66-66, 201610
  182. Is an Earlier and More Intensive Physical Therapy Program Better?, Am J Respir Crit Care Med., 194(8), 1032-1032, 201610
  183. Are probiotics actually useful in decreasing VAP rate?, Intensive Care Med., 42(10), 1643-1644, 201610
  184. Clinical and investigative critical care medicine in Japan., Intensive Care Med., 42(3), 453-455, 201603
  185. Emphysematous pancreatitis., Intensive Care Med., 42(6), 1075-1075, 2016
  186. Exploring Causative Pathology Is Essential for Validating Harmful Effects of Late Intubation., Crit Care Med, 44, e770-e771, 2016
  187. Prognostic implications of aspiration pneumonia in patients with community acquired pneumonia: A systematic review with meta-analysis, SCIENTIFIC REPORTS, 6, 2016
  188. Early mobilization of mechanically ventilated patients in the intensive care unit., J Intensive Care, 29(4), 50-50, 2016
  189. Clinical and investigative critical care medicine in Japan, INTENSIVE CARE MEDICINE, 42(3), 453-455, 2016
  190. Emphysematous pancreatitis, INTENSIVE CARE MEDICINE, 42(6), 1075-1075, 2016
  191. Exploring Causative Pathology Is Essential for Validating Harmful Effects of Late Intubation, CRITICAL CARE MEDICINE, 44(8), E770-E771, 2016
  192. Are probiotics actually useful in decreasing VAP rate?, INTENSIVE CARE MEDICINE, 42(10), 1643-1644, 2016
  193. Is an Earlier and More Intensive Physical Therapy Program Better?, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 194(8), 1032-1032, 2016
  194. Is transpulmonary pressure-guided PEEP titration really optimal?, INTENSIVE CARE MEDICINE, 42(11), 1845-1846, 2016
  195. Factors affecting biomarkers of endothelial and alveolar epithelial dysfunction, INTENSIVE CARE MEDICINE, 42(12), 2111-2112, 2016
  196. Potential covariates that affect post-extubation breathing effort in children, INTENSIVE CARE MEDICINE, 42(12), 2127-2128, 2016
  197. Exploring Potential Cofactors Affecting Coagulation and Inflammation Activity During Extracorporeal Membrane Oxygenation, CRITICAL CARE MEDICINE, 44(11), E1149-E1150, 2016
  198. Current rehabilitation practices in intensive care units: a preliminary survey by the Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group., J Intensive Care., 4(66), 2016
  199. Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and therapies study., Am J Respir Crit Care Med., 191(10), 1147-1157, 20150515
  200. Innovation, Cost, and Sustainability of Pediatric Ventricular Assist Device Programs., Pediatr Crit Care Med., 16(6), 589-590, 201507
  201. A survey of the competency of ambulance service personnel in the diagnosis and management of sepsis., J Emerg Med, 49(2), 147-151, 2015
  202. Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study., Crit Care., 19, 325-325, 2015
  203. Ultrasound Imaging Reduces Failure Rates of Percutaneous Central Venous Catheterization in Children., Pediatr Crit Care Med., 16(8), 718-725, 2015
  204. Polymyxin B haemoperfusion in septic shock patients., Intensive Care Med., 41(11), 2033-2033, 2015
  205. Respiratory rate criteria for pediatric systematic inlammatory response syndrome, Pediatr Crit Care Med, 15(2), 182-182, 2014
  206. A novel method for ultrasound-guided radial arterial catheterization in pediatric patients, Anesth Analg, 118(5), 1019-1026, 2014
  207. Invasive pulmonary aspergillosis in a patient presenting with idiopathic systemic capillary leak syndrome, BMJ Case Rep, 2014
  208. A pilot study of Bifidobacterium breve in neonates undergoing surgery for congenital heart disease, Journal of Intensive Care, 2(36), 2014
  209. Sepsis Registry Committee of The Japanese Society of intensive Care Medicine, Journal of Intensive Care, 2(55), 2014

Publications such as books

  1. 2016, Critical Care UPDATE, 2016, Single work, 日本語
  2. 2015, Critical Care UPDATE, 2015, Single work, 日本語
  3. 2015, Critical Care UPDATE, 2015, Single work, 日本語

Invited Lecture, Oral Presentation, Poster Presentation

  1. Regarding the current status and problems of SSCG/JSSCG, current problems and issues of PCT insurance assessment, timing of multiple measurements., Shime N, ThermoFisher Advisory board meeting in Japan, 2022/02/08, Without Invitation, English, ThermoFisher, WEB
  2. Emergency and ICU services of COVID-19 cases in Hiroshima University Hospital, Nobuaki SHime, Management of COVID-19 patients in Japan and Indosesia, 2020/06/04, With Invitation, English
  3. Ultrasound-guided catheter insertion in PICU, Shime N, The 7th World Congress on Pediatric Intensive and Critical Care, 2014/05/07, With Invitation, English, Istanbul
  4. Ventilator-associated events in pediatrics, Shime N, The 7th World Congress on Pediatric Intensive and Critical Care, 2014/05/07, With Invitation, English, Istanbul
  5. Comparison of three cutaneous antiseptic solutions for the prevention of catheter colonization in the adult intensive care unit : A multicenter prospective randomized controlled trial, Yasuda H, Sanui M, Komuro T, Hatakeyama J, Matsukubo S, Kawano S, Yamamoto H, Andoh K, Seo R, Shime N, The 35th international symposium on intensive and emergency medicine, 2015/03/18, With Invitation, English, Brussels
  6. Successful use of VAV ECMO in patient with respiratory failure complicated by myocarditis, M Kyo., S Ohshimo, Y Kida, T Shimatani, Y Torikoshi, K Suzuki, S Yamaga, N Hirohashi, N Shime, The 35th Annual Conference of KSCCM, 2016/04/23, Without Invitation, English
  7. Optimal Volume and Substance in Intraesophageal Balloon Catheter for Esophageal Pressure Measurement., T Shimatani, S Ohshimo, M Kyo, Y Kida, N Shime, The 35th Annual Conference of KSCCM, 2016/04/23, Without Invitation, Japanese
  8. Analysis of autopsy findings in patients with acute respiratory failure supported on V-V ECMO, Y Kida, S Ohshimo, M Kyo, T Shimatani, N Hirohashi, N Shime, The 35th Annual Conference of KSCCM, 2016/04/23, Without Invitation, Japanese
  9. Crinical Research in Japan., Shime N., Asia redional meeting in the 8th World Congress on Pedatric Intensive and Critical Care, 2016/06/05, Without Invitation, English, Tronto
  10. PREDICTORS FOR DETECTION OF DIFFICULT-TO-TREAT BACTERIA IN BILIARY TRACT INFECTION, Esaka N, Endo B, Shime N, 24th United European Gastroenterology Week, 2016/10, Without Invitation, English, Vienna
  11. Cimmunity-acquired and Healthcare-acquired pneumonia, Nobuaki Shime, Multiprofessional Critical Care Board Review Course in JAPAN 2016, 2016/11/19, With Invitation, English
  12. Utility of continuous monitoring and visualizing system for respiratory sounds., Kikutani K, Ohshimo S, Ohki S, Giga H, Yamaga S, Sadamori T, Shime N, 第46回日本集中治療医学会学術集会, 2019/03/01, Without Invitation, English, Kyoto
  13. Association between apporopriate empiric antimicrobial therapy and mortalitu from bloodstream infections in the intensive care unit., Yamaga S, Shime N, Ohshimo S., 第46回日本集中治療医学会学術集会, 2019/03/02, Without Invitation, English, Kyoto
  14. Infection control in emergency departments in Japan., Sasaki J, KudoD, Shiino Y, Ikeda H, Shime N, Yokota H, The 18th. International Congress of Emergency Medicine, 2019/04/12, Without Invitation, Japanese, The 18th. International Congress of Emergency Medicine, Seoul
  15. Infection control in emergency departments in Japan., Sasaki J, KudoD, Shiino Y, Ikeda H, Shime N, Yokota H, The 18th. International Congress of Emergency Medicine, 2019/04/12, Without Invitation, English, Seoul
  16. Survey for infection control in emergency departments in Japan., Sasaki J, KudoD, Shiino Y, Ikeda H, Shime N, Ohge H, The 29th European Congress of Clinical Microbiology and Infectious Diseases, 2019/04/13, Without Invitation, English, The 29th European Congress of Clinical Microbiology and Infectious Diseases, Amsterdam, Netherlands
  17. ASPECT-NP: a randomized, double-blind, phase III trial comparing efficacy and safety of ceftolozane/tazobactam versus meropenem in patients with ventilated nosocomial pneumonia (VNP), Kollef M, Novacek M, Kivisitk Ü, Réa-Neto Á, Shime N, Martin-Loeches I, Timsit J-F, Wunderink RG, Bruno CJ, Huntington JA, Lin K, Yu B, Butterton JR, Rhee EG., The 29th European Congress of Clinical Microbiology and Infectious Diseases, 2019/04/13, Without Invitation, English, The 29th European Congress of Clinical Microbiology and Infectious Diseases, Amsterdam, Netherlands
  18. Survey for infection control in emergency departments in Japan., Sasaki J, KudoD, Shiino Y, Ikeda H, Shime N, Ohge H., The 29th European Congress of Clinical Microbiology and Infectious Diseases, 2019/04/13, Without Invitation, English, Amsterdam, Netherlands
  19. Clinical and microbiologic outcomes by causative pathogen in the ASPECT-NP randomized, controlled, phase 3 trial evaluating ceftolozane/tazobactam for treatment of ventilated nosocomial pneumonia (VNP), Martin-Loeches I, Kivisitk Ü, Nováček M, Rea-Neto A, Timsit J-F, Shime N, Wunderink RG, Kollef M, Bruno CJ, Huntington JA, Lin G, Yu B, Butterton JR, Rhee EG, The 22nd Annual MAD-ID Meeting, 2019/05/08, Without Invitation, English, The 22nd Annual MAD-ID Meeting, Orlando,Floroda
  20. ASPECT-NP: a randomized, double-blind, phase 3 trial comparing efficacy and safety of ceftolozane/tazobactam versus meropenem in patients with ventilated nosocomial pneumonia (VNP), Kollef M, Novacek M, Kivisitk U, Rea-Neto A, Shime N, Martin-Loeches I, Timsit J-F, Wunderink R, Bruno C, Huntington J, Lin K, Yu B, Butterton JR, Rhee EG, The 22nd Annual MAD-ID Meeting, 2019/05/08, Without Invitation, English, The 22nd Annual MAD-ID Meeting, Orlando,Floroda
  21. Outcomes in patients with ventilated nosocomial pneumonia (NP) and organ failure treated with ceftolozane/tazobactam (C/T) vs meropenem (MER) - analysis of the ASPECT-NP randomized, controlled trial., Martin-Loeches I, Bruno CJ, Shime N, Wunderink RG, Kollef M, Kivistik Ü, Nováček M, Réa-Neto A, Timsit J-F, Yu B, Huntington JA, Jensen E, Butterton JR, Rhee EG, Shorr AF., ESICM (2019) European Society of Intensive Care Medicine 32nd Annual Congress., 2019/09/30, Without Invitation, English, ESICM, Berlin
  22. Ceftolozane/tazobactam (C/T) vs meropenem (MEM) in patients with ventilated hospital-acquired pneumonia (vHAP) – subset analysis of the ASPECT-NP randomized, controlled, phase 3 trial., Timsit J-F, Huntington JA, Wunderink RG, Shime N, Kollef M, Kivistik Ü, Nováček M, Réa-Neto A, Martin-Loeches I, Yu B, Bruno CJ, Jensen E, Butterton JR, Wolf DJ, Rhee EG., ESICM (2019) European Society of Intensive Care Medicine 32nd Annual Congress., 2019/09/30, Without Invitation, English, ESICM (2019) European Society of Intensive Care Medicine 32nd Annual Congress., Berlin

External Funds

Acceptance Results of Competitive Funds

  1. 2021, 2022
  2. 2011, 2014
  3. 2012, 2016
  4. 2014, 2014
  5. 2017, 2019
  6. 2017, 2019
  7. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2017, 2019
  8. 2017/.4, 2018/.3
  9. 2017/.6
  10. Development of Medical Devices and Systems for Advanced Medical Services , 2017/08/01, 2018/03/31
  11. Development of Medical Devices and Systems for Advanced Medical Services , 2018/04/01, 2019/03/31
  12. Development of Medical Devices and Systems for Advanced Medical Services, Development of Medical Devices and Systems for Advanced Medical Services, 2019, 2019
  13. 2019, 2020
  14. Acceleration Transformative Research for Medical Innovation, 2019/04/01, 2020/03/31
  15. 2020, 2020
  16. KAKENHI(Grant-in-Aid for Scientific Research (B)), 2020, 2023
  17. Acceleration Transformative Research for Medical Innovation, 2020/04/01, 2021/09/30
  18. 2020, 2021
  19. Development of Medical Devices and Systems for Advanced Medical Services, Development of Medical Devices and Systems for Advanced Medical Services, 2020, 2020

Social Activities

History as Committee Members

  1. 2016, 2022

Organizing Academic Conferences, etc.

  1. INTERNATIONAL SERIAL VIRTUAL WEBINAR MANAGEMENT OF COVID-19 PATIENTS IN JAPAN AND VIETNAM, Chair, 2021/11, 2021/11
  2. 2020/12, 2020/12
  3. 2018/12, 2018/12
  4. 2018/05, 2018/05
  5. 2018/10, 2018/10
  6. 2017/06, 2017/06
  7. 2016/06, 2016/06
  8. 2017/05, 2017/05
  9. 2016/09, 2016/09

Other Social Contributions

  1. ECMO simulation labo., ECMO simulation labo., NPO ECMO JAPAN, 2019/08/31, 2019/09/01, Planner, Seminar or workshop, Scientific organization
  2. ECMO simulation labo., ECMO simulation labo., NPO ECMO JAPAN, 2017/05/27, 2017/05/28, Planner, Seminar or workshop, Scientific organization
  3. PALS provider course, PALS provider course, JIPICC, 2019/08/17, 2019/08/18, Planner, Seminar or workshop, Scientific organization

History as Peer Reviews of Academic Papers

  1. 2021, British Journal of Anaesthesia, Others, 1
  2. 2021, Journal of Pediatric Intensive Care, Others, 1
  3. 2021, The Journal of Medical Investigation, Others, 1
  4. 2021, J of Perinatoloigy, Others, 1
  5. 2021, Frontiers in Medicine, Others, 1
  6. 2021, Clinical Infectious Disease, Others, 1
  7. 2021, BMJ case reports, Others, 2
  8. 2021, Japanese Medical Association Journal, Others, 1
  9. 2021, Scandinavian J of Trauma and Resuscitation, Others, 1
  10. 2021, J of Thoracic Disease, Others, 1
  11. 2020, International Journal of Infectious Diseases, 1
  12. 2020, Acute Medicine & Surgery, 4
  13. 2020, BMJ open, 2
  14. 2020, Cardiovascular Diagnosis and Therapy, 1
  15. 2020, Journal of International Medical Research, Others, 1
  16. 2020, Journal of Japanese Association for Acute Medicine, 4
  17. 2020, J of Artificial Organs, 2
  18. Liver International, 1
  19. 2020, Pediatrics International, 1
  20. 2020, Respiratory Medicine Case Reports, 4
  21. 2020, The Lancet Regional health western pacific, 1
  22. 2020, J Clinical Microbiology, Others, 1
  23. 2020, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2
  24. 2020, J of Infection and Chemotherapy, 6
  25. 2020, Pediatric Critical Care Medicine, Editor, Associate Editor, 14
  26. 2021, INTENSIVIST, Editor, 1
  27. 2020, J Intensive Care, Editor, 14
  28. 2019, Infect Drug Resist, 3
  29. Pros One, Others, 1
  30. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Others, 1
  31. 2019, Clinical Interventions in Aging, Others, 1
  32. 2019, Pedaitr Crit Care Med, Editor, 11
  33. 2019, J Intensive care, Editor, 5
  34. 2018, J of Artif Organs, Others, 2
  35. 2018, J Antimicrobial Chemother, 1
  36. 2018, Med Sci Monitoring, Others, 1
  37. 2018, Int J Infect Dis, Others, 1
  38. 2018, Clinical epidemiology, Others, 1
  39. 2018, BMC pediatrics, Others, 1
  40. 2018, J Infect Chemother, Others, 4
  41. 2018, Pediatr Crit Care Med, Editor, 11
  42. 2018, J intensive care, Others, Deputy Editor, 15
  43. 2017, Acute Medicine and Surgery, Others, 1
  44. 2017, BMC pediatrics, Others, 1
  45. 2017, European Respiratory Reviews, Others, 1
  46. 2017, BMC Anesthesiology, Others, 1
  47. 2017, J Artif Organs, Others, 1
  48. 2017, Pulsus Journals, Others, 1
  49. 2017, J Antimicrobial Chemother, Others, 1
  50. 2017, J of Infection and Chemotherapy, Others, 2
  51. 2017, J of Anesthesia, Others, 5
  52. 2017, Pediatr Crit Care Med, Editor, 16
  53. 2017, Pediatrics International, Editor, 9
  54. 2017, Journal of Intensive Care, Editor, 4
  55. 2016, Internal Medicine, Others, 1
  56. 2016, Journal of Cirtical Care, Others, 1
  57. 2016, Hospital practice, Others, 1
  58. 2016, Respiratory Medicine Case Reports, Others, 1
  59. 2016, BMC Anesthesiology, Others, 1
  60. 2016, Journal of Anesthesia, Others, 3
  61. 2016, Pediatrics international, Editor, 10
  62. 2016, Journal of Infection and Chemotherapy, Editor, 2
  63. 2016, Pediatric Critical Care Medicine, Editor, 12
  64. 2016, Journal of Intensive Care, Editor, 6
  65. 2015, Circulation Journal, Others, Reviewer, 1
  66. 2015, Hospital Practice, Others, Reviewer, 1
  67. 2015, Journal of Infection and Chemotherapy, Reviewer, 4
  68. 2015, Journal of Anesthesia, Editor, Reviewer, 4
  69. 2015, Journal of Japanese Society of Intensive Care Medicine, Others, Reviewer, 2
  70. 2015, Journal of Japanese Sciety of Surgical Infection, Editor, Editor, 4
  71. 2015, Journal of Intensive Care, Editor, Reviewer, 17
  72. 2015, Journal of Intensive Care, Editor, Associate Editor, 4
  73. 2015, Pediatrics International, Editor, Editor, 71
  74. 2015, Pediatric Critical Care Medicine, Editor, Associate Editor, 15
  75. 2015, Pediatrics International, Others, Reviewer, 2
  76. 2021, J Intensive Care, Editor, Deputy Editor, 141
  77. 2021, Acute Medicine & Surgery, 2
  78. 2021, J of Anesthesia, Others, 1
  79. 2021, Pediatric Critical Care Medicine, Editor, Associate Editor, 1
  80. 2021, Journal of Infection and Chemotherapy, Editor, 1
  81. 2021, BMC pediatrics, Others, 1
  82. 2021, International Journal of Infectious Diseases, Others, 3
  83. 2021, BMJ open, Others, 1
  84. 2021, Infect Drug Resist, Others, 1