NOBUAKI SHIME

Last Updated :2025/07/15

Affiliations, Positions
Graduate School of Biomedical and Health Sciences, Professor
E-mail
nshimehiroshima-u.ac.jp
Self-introduction
Emergency and Critical Care Medicine

Basic Information

Major Professional Backgrounds

  • 2020, Kyoto Prefectural University of Medicine, Visiting Professor
  • 2020, Doshisha University, Visiting Professor

Academic Degrees

  • Kyoto Prefectural University of Medicine

Educational Activity

  • [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
  • [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Emergency medicine

Research Keywords

  • sepsis, antibiotics, pneumonia, ECMO, ARDS

Affiliated Academic Societies

  • Japanese Society of Intensive Care Medicine
  • Japanese Association of Acute Medicine
  • Japanese Society of Infectious Disease
  • Japanese Society of Antimicrobial and Chemotherapy

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, Year, Systemic Disease Control
  2. 2025, Undergraduate Education, Intensive, Practice for medical research
  3. 2025, Undergraduate Education, Intensive, Practice of Medicine I
  4. 2025, Undergraduate Education, Intensive, Practice of Medicine II
  5. 2025, Undergraduate Education, Second Semester, Emergency and Critical Care Medicine
  6. 2025, Graduate Education (Master's Program) , 2Term, Multidisciplinary Cooperation A
  7. 2025, Graduate Education (Doctoral Program) , 2Term, Multidisciplinary Cooperation B
  8. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Emergency and Critical Care Medicine
  9. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Emergency and Critical Care Medicine
  10. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Emergency and Critical Care Medicine
  11. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Emergency and Critical Care Medicine

Research Activities

Academic Papers

  1. Prognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings, Crit Care., 28(1), 30, 202401
  2. Long-term, patient-centered, frailty-based outcomes of older critical illness survivors from the emergency department: a post hoc analysis of the LIFE Study, BMC Geriatr, 24(1), 257, 202403
  3. Critical insights into venoarterial extracorporeal membrane oxygenation outcomes in immunocompromised patients: addressing uncertainties in cause of death and treatment strategies., Intensive Care Med, 50(8), 1395-1396, 202408
  4. Rate of Asthma Prescriptions for Children and Adolescents During the 2018 Floods in Japan., Pediatrics, 154(3), 202409
  5. Complex interaction of infusion volumes and confounding factors with lactate clearance in septic shock., Intensive Care Med, 50(9), 1545-1546, 202409
  6. Combination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial., Crit Care Med, 52(10), 1567-1576, 202410
  7. Respiratory physiotherapy for critically ill children: concern regarding a recommendation, J Intensive Care, 12(1), 51-51, 202412
  8. Limitation of life-sustaining treatments in Asian ICUs: theory versus practice., Crit Care, 29(1), 9-9, 202501
  9. Dental Suction Interference and Acoustic Respiratory Monitoring., Anesth Prog, 71(4), 171-175, 202501
  10. Molecular endotypes in sepsis: integration of multicohort transcriptomics based on RNA sequencing, JOURNAL OF INTENSIVE CARE, 13(1), 20250530
  11. Efficacy of tranexamic acid in adult isolated traumatic brain injury: A multicenter retrospective study, AMERICAN JOURNAL OF EMERGENCY MEDICINE, 95, 173-178, 202509
  12. Immunocompromised-Associated Pediatric Acute Respiratory Distress Syndrome: Experience From the 2016/2017 Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Prospective Cohort Study, PEDIATRIC CRITICAL CARE MEDICINE, 25(4), 288-300, 202404
  13. Local Adverse Events Associated with Peripheral Vasoactive Infusion in Children: A Systematic Review with Meta-analysis, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 38(12), 3215-3223, 202412
  14. Cross-sectional pilot study of relationships between specific oral bacteria and acute respiratory failure requiring intensive care unit admission, JOURNAL OF DENTISTRY, 157, 202506
  15. Association between increasing institutional experience with ECPR and outcomes in patients with out-of-hospital cardiac arrest: A nationwide multicenter observational study in Japan (the JAAM-OHCA registry), RESUSCITATION, 209, 202504
  16. Impact of Noradrenaline Administration Dosage on the Occurrence of Peripheral Intravenous Catheter-Related Venous Phlebitis in Critically Ill Patients Using a Time-Dependent Multilevel Cox Regression Model, EMERGENCY MEDICINE INTERNATIONAL, 2025(1), 2025
  17. Risk factors of phlebitis in patients admitted to the intensive care unit vary according to the duration of catheter dwelling: A post-hoc analysis of the AMOR-VENUS study, PLOS ONE, 20(4), 20250430
  18. Characteristics of Bleeding Complications in Patients with Severe COVID-19 Requiring Veno-venous Extracorporeal Membrane Oxygenation in Japan, THROMBOSIS AND HAEMOSTASIS, 125(04), 308-316, 202504
  19. Changes in the neurological status from 30 to 90 days post-cardiac arrest by age: A nationwide retrospective observational study, RESUSCITATION PLUS, 22, 202503
  20. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024, JOURNAL OF INTENSIVE CARE, 13(1), 20250314
  21. Differential Effects of the Prolyl-Hydroxylase Inhibitor on the Cellular Response to Radiation, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 26(6), 20250318
  22. Association between hospital case volume and mortality in pediatric sepsis: A retrospective observational study using a Japanese nationwide inpatient database, JOURNAL OF CRITICAL CARE MEDICINE, 11(1), 87-94, 20250101
  23. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024, ACUTE MEDICINE & SURGERY, 12(1), 202501
  24. Effect Size of Targeted Temperature Management in Pediatric Patients with Post-Cardiac Arrest Syndrome According to the Severity, LIFE-BASEL, 15(1), 202501
  25. Tranexamic Acid in Pediatric Traumatic Brain Injury: A Multicenter Retrospective Observational Study, ANNALS OF EMERGENCY MEDICINE, 85(2), 101-108, 202502
  26. At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods, SCIENTIFIC REPORTS, 14(1), 20240717
  27. Resuscitation Attempt and Outcomes in Patients With Asystole Out-of-Hospital Cardiac Arrest, JAMA NETWORK OPEN, 7(11), 20241118
  28. External validation of the sICOP score for early mortality in mechanically ventilated patients with COVID-19, ACUTE MEDICINE & SURGERY, 11(1), 202401
  29. Identification of novel sub-phenotypes of severe ARDS requiring ECMO using latent class analysis, CRITICAL CARE, 28(1), 20241024
  30. Diagnostic utility of plasma translocator protein 18 kDa (TSPO) in sepsis: A case-control study, MEDICINE, 103(44), 20241101
  31. Increased national critical care demands were associated with a higher mortality of intubated COVID-19 patients in Japan: a retrospective observational study, JOURNAL OF INTENSIVE CARE, 12(1), 20241105
  32. The Usefulness of Continuous Respiratory Sound Monitoring for the Detection of Pulmonary Atelectasis in a Ventilated Extremely Low Birth Weight Infant, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(7), 20240725
  33. Development of a Machine Learning-Based Model for Predicting the Incidence of Peripheral Intravenous Catheter-Associated Phlebitis, JOURNAL OF CRITICAL CARE MEDICINE, 10(3), 232-244, 20240701
  34. Association of Intensive Care Unit Case Volume With Mortality and Cost in Sepsis Based on a Japanese Nationwide Medical Claims Database Study, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(7), 20240729
  35. Epidemiology of moderate traumatic brain injury and factors associated with poor neurological outcome, JOURNAL OF NEUROSURGERY, 141(2), 430-435, 202408
  36. Identifying Subgroups with Differential Responses to Amiodarone among Cardiac Arrest Patients with a Shockable Rhythm at Hospital Arrival using the Machine Learning Approach, REVIEWS IN CARDIOVASCULAR MEDICINE, 25(7), 202407
  37. Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms, HELIYON, 10(10), 20240530
  38. Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study, LANCET RESPIRATORY MEDICINE, 11(5), 465-476, 202305
  39. Characteristics and outcomes of an international cohort of 600000 hospitalized patients with COVID-19, INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 202328
  40. Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19, KIDNEY INTERNATIONAL REPORTS, 8(8), 1514-1530, 202308
  41. Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry, RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS, 7(5), 202307
  42. Noninvasive Ventilation for Pediatric Acute Respiratory Distress Syndrome: Experience From the 2016/2017 Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Prospective Cohort Study, PEDIATRIC CRITICAL CARE MEDICINE, 24(9), 715-726, 202309
  43. Neurological manifestations of COVID-19 in adults and children, BRAIN, 146(4), 1648-1661, 202304
  44. Bacterial profiles detected in ventilator-associated pneumonia in Japan: A systematic review, RESPIRATORY INVESTIGATION, 62(3), 365-368, 202405
  45. The Current Discussion Regarding End-of-Life Care for Patients with Out-of-Hospital Cardiac Arrest with Initial Non-Shockable Rhythm: A Narrative Review, MEDICINA-LITHUANIA, 60(4), 202404
  46. External validation of the rCAST for patients after in-hospital cardiac arrest: a multicenter retrospective observational study, SCIENTIFIC REPORTS, 14(1), 20240221
  47. Differences in Pathophysiology and Treatment Efficacy Based on Heterogeneous Out-of-Hospital Cardiac Arrest, MEDICINA-LITHUANIA, 60(3), 202403
  48. Epidemiology and patterns of empiric antimicrobial therapy practice in patients with community-onset sepsis using data from a Japanese nationwide medical claims database -the Japan Sepsis Alliance (JaSA) study group, IJID REGIONS, 10, 162-167, 202403
  49. High versus low positive end-expiratory pressure setting in patients receiving veno-venous extracorporeal membrane oxygenation support for severe acute respiratory distress syndrome: study protocol for the multicentre, randomised ExPress SAVER Trial, BMJ OPEN, 13(10), 202310
  50. Predictive Accuracy of the ROX Index for Re-Intubation in Mechanically Ventilated Patients With COVID-19, RESPIRATORY CARE, 68(8), 1067-1074, 20230801
  51. Association between hospital spending and in-hospital mortality of patients with sepsis based on a Japanese nationwide medical claims database study, HELIYON, 10(1), 20240115
  52. New acoustic monitoring system quantifying aspiration risk during monitored anaesthesia care, SCIENTIFIC REPORTS, 13(1), 20231118
  53. Usefulness of new acoustic respiratory sound monitoring with artificial intelligence for upper airway assessment in obese patients during monitored anesthesia care, JOURNAL OF MEDICAL INVESTIGATION, 70(3-4), 430-435, 202308
  54. Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry, JOURNAL OF INTENSIVE CARE, 12(1), 20240126
  55. Association between regional critical care capacity and the incidence of invasive mechanical ventilation for coronavirus disease 2019: a population-based cohort study, JOURNAL OF INTENSIVE CARE, 12(1), 20240130
  56. Carbapenem vs. non-carbapenem antibiotics for ventilator-associated pneumonia: A systematic review with meta-analysis, RESPIRATORY INVESTIGATION, 62(2), 200-205, 202403
  57. A Successful Prevention of Reintubation Using the Mechanical Insufflation-Exsufflation in a Critically Ill Patient With Impaired Airway Mucus Expectoration: A Case Report, CUREUS JOURNAL OF MEDICAL SCIENCE, 15(10), 20231027
  58. Prediction of the neurological outcomes post-cardiac arrest: A prospective validation of the CAST and rCAST, AMERICAN JOURNAL OF EMERGENCY MEDICINE, 75, 46-52, 202401
  59. Ultrasound-Guided Short-Axis Out-of-Plane Approach With or Without Dynamic Needle-Tip Positioning for Peripheral Venous Catheterization in Pediatric Patients: A Systematic Review With Network Meta-Analysis, JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 37(10), 2057-2064, 202310
  60. Comparison of radial, dorsalis pedis, and posterior tibial arteries for ultrasound-guided arterial catheterisation with dynamic needle tip positioning in paediatric patients: a randomised controlled trial, BRITISH JOURNAL OF ANAESTHESIA, 131(4), 739-744, 202310
  61. Efficacy of perioperative prophylactic administration of corticosteroids in pediatric cardiac surgeries using cardiopulmonary bypass: a systematic review with meta-analysis, ANAESTHESIA CRITICAL CARE & PAIN MEDICINE, 42(6), 202312
  62. Multisystem inflammatory syndrome in adults with COVID-19 requiring mechanical ventilation: A retrospective cohort study, ACUTE MEDICINE & SURGERY, 10(1), 202301
  63. Use of a laryngeal tube for sialolithotomy in a pediatric patient with left vocal cord paralysis: a case report, JA CLINICAL REPORTS, 9(1), 20230617
  64. ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19, SCIENTIFIC DATA, 9(1), 20220730
  65. Impact of frailty on long-term mortality in older patients receiving intensive care via the emergency department, SCIENTIFIC REPORTS, 13(1), 20230403
  66. Impact of the failure of initial insertion of a peripheral intravascular catheter on the development of adverse events in patients admitted to the intensive care unit from the emergency room: A post hoc analysis of the AMOR-VENUS study, ACUTE MEDICINE & SURGERY, 10(1), 202301
  67. Lethal Interstitial Lung Disease Associated with a Gain-of-Function Mutation in IFIH1., J Clin Immunol, Epub ahead of print, 202305
  68. Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study., Lancet Respir Med, 11(5), 465-476, 20230121
  69. Temperature management using an intervascular cooling device for a COVID-19 patient with refractory hyperthermia., Clin Case Rep, 11(4), e7138-e7138, 20230407
  70. Impact of frailty on long-term mortality in older patients receiving intensive care via the emergency department., Sci Rep, 13(1), 5433-5433, 20230403
  71. Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19., Int J Epidemiol, 52(2), 355-376, 20230419
  72. Neurological manifestations of COVID-19 in adults and children. Brain., Brain, 146(6), 1648-1661, 20230419
  73. Efficacy of inhaled hydrogen on neurological outcome following brain ischaemia during post- cardiac arrest care (HYBRID II): a multi-centre, randomised, double-blind, placebo-controlled trial., EClinicalMedicine, 58, 101907, 20230317
  74. A study of the risk factors for phlebitis in patients stratified using the acute physiology and chronic health evaluation II score and admitted to the intensive care unit: A post hoc analysis of the AMOR-VENUS study., Front Med (Lausanne)., 9, 965706, 20221205
  75. An algorithm for PCT-guided antimicrobial therapy: a consensus statement by Japanese experts., Clin Chem Lab Med, 61(3), 407-411, 20221202
  76. Risk factors for peripheral venous catheter- related phlebitis stratified by body mass index in critically ill patients: A post-hoc analysis of the AMOR-VENUS study., Front Med (Lausanne), 9, 1037274, 20221128
  77. Unexpected cholinergic crisis caused by distigmine bromide: A case report., Medicine (Baltimore), 101(47), e31677-e31677, 20221125
  78. Trends in survival during the pandemic in patients with critical COVID-19 receiving mechanical ventilation with or without ECMO: analysis of the Japanese national registry data., Crit Care, 26(1), 354-354, 20221115
  79. Short- versus long-course antibiotic therapy for sepsis: a post hoc analysis of the nationwide cohort study., J Intensive Care, 10(1), 49-49, 20221029
  80. A burden of fluid, sodium, and chloride due to intravenous fluid therapy in patients with respiratory support: a post-hoc analysis of a multicenter cohort study., Ann Intensive Care, 12(1), 100-100, 20221022
  81. Japanese rapid/living recommendations on drug management for COVID-19: updated guidelines (July 2022)., Acute Med Surg, 9(1), e789-e789, 20221019
  82. The research environment of critical care in three Asian countries: A cross-sectional questionnaire survey., Front Med (Lausanne), 9, 975750, 20220920
  83. Controversial Efficacy of Prone-Positioning for Patients With Severe Acute Respiratory Distress Syndrome Undergoing Venous-Venous Extracorporeal Membrane Oxygenation., Crit Care Med, 50(9), e725-e726, 202209
  84. Effect of wearing a surgical mask on short-term pulmonary gas exchange in patients immediately after anaesthesia., Indian J Anaesth., 66(8), 617-619, 202208
  85. Characteristics of the pulmonary opacities on chest CT associated with difficulty in short-term liberation from veno-venous ECMO in patients with severe ARDS, RESPIRATORY RESEARCH, 24(1), 20230510
  86. Ultrasound-guided short-axis out-of-plane approach with or without dynamic needle tip positioning for arterial line insertion in children: A systematic review with network meta-analysis, ANAESTHESIA CRITICAL CARE & PAIN MEDICINE, 42(3), 202306
  87. Temperature management using an intervascular cooling device for a COVID-19 patient with refractory hyperthermia, CLINICAL CASE REPORTS, 11(4), 202304
  88. An algorithm for PCT-guided antimicrobial therapy: a consensus statement by Japanese experts, CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 61(3), 407-411, 20230223
  89. The Current and Future State of Pediatric Sepsis Definitions: An International Survey, PEDIATRICS, 149(6), 202206
  90. GENETIC DELETION OF TRANSLOCATOR PROTEIN EXACERBATES POST-SEPSIS SYNDROME WITH ACTIVATION OF THE C1Q PATHWAY IN SEPTIC MOUSE MODEL, SHOCK, 59(1), 82-90, 202301
  91. Combined short-axis out-of-plane and long-axis in-plane approach versus long-axis in-plane approach for ultrasound-guided central venous catheterization in infants and small children: A randomized controlled trial, PLOS ONE, 17(9), 20220930
  92. Case Report: Emphysematous Pyelonephritis With a Congenital Giant Ureterocele, FRONTIERS IN PEDIATRICS, 9, 20211126
  93. Quantification of respiratory sounds by a continuous monitoring system can be used to predict complications after extubation: a pilot study, JOURNAL OF CLINICAL MONITORING AND COMPUTING, 37(1), 237-248, 202302
  94. Unexpected cholinergic crisis caused by distigmine bromide: A case report, MEDICINE, 101(47), 20221125
  95. Risk factors for peripheral venous catheter-related phlebitis stratified by body mass index in critically ill patients: A post-hoc analysis of the AMOR-VENUS study, FRONTIERS IN MEDICINE, 9, 20221128
  96. A study of the risk factors for phlebitis in patients stratified using the acute physiology and chronic health evaluation II score and admitted to the intensive care unit: A post hoc analysis of the AMOR-VENUS study, FRONTIERS IN MEDICINE, 9, 20221205
  97. Deep sedation predicts pressure injury in patients admitted to intensive care units, NURSING IN CRITICAL CARE, 27(6), 877-884, 202211
  98. Mortality analysis among sepsis patients in and out of intensive care units using the Japanese nationwide medical claims database: a study by the Japan Sepsis Alliance study group, JOURNAL OF INTENSIVE CARE, 11(1), 20230107
  99. Neutralizing Type I Interferon Autoantibodies in Japanese Patients with Severe COVID-19, JOURNAL OF CLINICAL IMMUNOLOGY, 42(7), 1360-1370, 202210
  100. ARDS clinical practice guideline 2021, RESPIRATORY INVESTIGATION, 60(4), 446-495, 202207
  101. Trends in survival during the pandemic in patients with critical COVID-19 receiving mechanical ventilation with or without ECMO: analysis of the Japanese national registry data, CRITICAL CARE, 26(1), 20221115
  102. A burden of fluid, sodium, and chloride due to intravenous fluid therapy in patients with respiratory support: a post-hoc analysis of a multicenter cohort study, ANNALS OF INTENSIVE CARE, 12(1), 20221022
  103. The research environment of critical care in three Asian countries: A cross-sectional questionnaire survey, FRONTIERS IN MEDICINE, 9, 20220920
  104. Regional respiratory sound abnormalities in pneumothorax and pleural effusion detected via respiratory sound visualization and quantification: case report, JOURNAL OF CLINICAL MONITORING AND COMPUTING, 36(6), 1761-1766, 202212
  105. Japanese rapid/living recommendations on drug management for COVID-19: updated guidelines (July 2022), ACUTE MEDICINE & SURGERY, 9(1), 202201
  106. Short- versus long-course antibiotic therapy for sepsis: a post hoc analysis of the nationwide cohort study, JOURNAL OF INTENSIVE CARE, 10(1), 20221029
  107. Incidence of catheter-related bloodstream infections following ultrasound-guided central venous catheterization: a systematic review and meta-analysis, BMC INFECTIOUS DISEASES, 22(1), 20221004
  108. Controversial Efficacy of Prone-Positioning for Patients With Severe Acute Respiratory Distress Syndrome Undergoing Venous-Venous Extracorporeal Membrane Oxygenation., Crit Care Med, 50(9), e725-e726, 20220901
  109. Purpura fulminans due to Rickettsia japonica., QJM, 115(11), 758-759, 20221114
  110. ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19., Sci Data, 9(1), 454, 20220730
  111. Alarming of Severe Respiratory Failure Requiring ECMO Caused by the SARS-CoV-2 Omicron Variant., JMA J, 5(3), 370-371, 20220715
  112. Temporal trends of medical cost and cost-effectiveness in sepsis patients: a Japanese nationwide medical claims database, JOURNAL OF INTENSIVE CARE, 10(1), 20220714
  113. ARDS Clinical Practice Guideline 2021, JOURNAL OF INTENSIVE CARE, 10(1), 20220708
  114. ARDS clinical practice guideline 2021, Respir Investig, 60(4), 446-495, 20220701
  115. Effect of region-wide use of prehospital stroke triage scale on management of patients with acute stroke, JOURNAL OF NEUROINTERVENTIONAL SURGERY, 14(7), 677-682, 20220701
  116. Neutralizing Type I Interferon Autoantibodies in Japanese Patients With Severe COVID-19., J Clin Immunol, 42(7), 1360-1370, 202210
  117. Quantification of respiratory sounds by a continuous monitoring system can be used to predict complications after extubation: a pilot study., J Clin Monit Comput, Epub ahead of print, 20220622
  118. Prediction of Prehospital Change of the Cardiac Rhythm From Nonshockable to Shockable in Out-of-Hospital Patients With Cardiac Arrest: A Post Hoc Analysis of a Nationwide, Multicenter, Prospective Registry, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 11(12), 20220621
  119. The Current and Future State of Pediatric Sepsis Definitions: An International Survey, Pediatrics, 149(6), 20220601
  120. Resource-rich Intensive Care Units Improve Health-What Is Next?, JMA J, 5(2), 285, 20220415
  121. Risk factors for peripheral intravascular catheter-related phlebitis in critically ill patients: analysis of 3429 catheters from 23 Japanese intensive care units, ANNALS OF INTENSIVE CARE, 12(1), 20220408
  122. Clinical and microbiological outcomes, by causative pathogen, in the ASPECT-NP randomized, controlled, Phase 3 trial comparing ceftolozane/tazobactam and meropenem for treatment of hospital-acquired/ventilator-associated bacterial pneumonia, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(4), 1166-1177, 20220331
  123. Short- versus prolonged-course antibiotic therapy for sepsis or infectious diseases in critically ill adults: a systematic review and meta-analysis, INFECTIOUS DISEASES, 54(3), 213-223, 20220304
  124. Regional respiratory sound abnormalities in pneumothorax and pleural effusion detected via respiratory sound visualization and quantification: case report., J Clin Monit Comput, Epub ahead of print, 20220211
  125. Real-time assessment of swallowing sound using an electronic stethoscope and an artificial intelligence system., Clin Exp Dent Res, 8(1), 225-230, 20220201
  126. Deep sedation predicts pressure injury in patients admitted to intensive care units., Nurs Crit Care, Epub ahead of print, 20220119
  127. Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study., Crit Care, 26(1), 2, 20220103
  128. Potential Confounders in Evaluating the Impact of Hyperoxia on Neurological Outcomes in Patients Receiving Extracorporeal Membrane Oxygenation., Crit Care Med, 50(1), e97-e98, 20220101
  129. Concerning the Association Between Delayed Administration of Antibiotics and Mortality in Patients With Suspected Sepsis., Crit Care Med, 50(1), e87-e88, 20220101
  130. Changes in pediatric intensive care unit cases due to the novel coronavirus., Pediatr Int, 64(1), e15019, 20220101
  131. Real-time assessment of swallowing sound using an electronic stethoscope and an artificial intelligence system, CLINICAL AND EXPERIMENTAL DENTAL RESEARCH, 8(1), 225-230, 202202
  132. A novel system that continuously visualizes and analyzes respiratory sounds to promptly evaluate upper airway abnormalities: a pilot study, JOURNAL OF CLINICAL MONITORING AND COMPUTING, 36(1), 221-226, 202202
  133. Changes in pediatric intensive care unit cases due to the novel coronavirus, PEDIATRICS INTERNATIONAL, 64(1), 202201
  134. Duration of infectious virus shedding in patients with severe coronavirus disease 2019 who required mechanical ventilation, JOURNAL OF INFECTION AND CHEMOTHERAPY, 28(1), 19-23, 202201
  135. Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort., Elife., e70970, 20211123
  136. Trends in the incidence and outcome of sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group, CRITICAL CARE, 25(1), 20210916
  137. The Association between Wearing a Mask and COVID-19, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(17), 20210901
  138. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), JOURNAL OF INTENSIVE CARE, 9(1), 20210825
  139. Patient-ventilator asynchrony, impact on clinical outcomes and effectiveness of interventions: a systematic review and meta-analysis, JOURNAL OF INTENSIVE CARE, 9(1), 20210816
  140. Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial, CRITICAL CARE, 25(1), 20210811
  141. Pharmacological and Genetic Inhibition of Translocator Protein 18 kDa Ameliorated Neuroinflammation in Murine Endotoxemia Model, SHOCK, 56(1), 142-149, 20210701
  142. Pediatric Fulminant Myocarditis in Japan: A Retrospective Nationwide Database Study of Hospital Volume, Management Practices, and Mortality, PEDIATRIC CRITICAL CARE MEDICINE, 22(7), E391-E401, 20210701
  143. Unclear Benefit of Early Tracheostomy In Patients With Coronavirus Disease 2019, Crit Care Med, 49(7), 721-722, 20210701
  144. The right care at the right place: Significance of intensive care units for critically ill patients., Lancet Reg Health West Pac, 13, 100198, 20210620
  145. Prevalence of rapid response systems in small hospitals A questionnaire survey, MEDICINE, 100(23), 20210611
  146. Frequency and Risk Factors for Reverse Triggering in Pediatric Acute Respiratory Distress Syndrome during Synchronized Intermittent Mandatory Ventilation, ANNALS OF THE AMERICAN THORACIC SOCIETY, 18(5), 820-829, 20210501
  147. Association of noninvasive respiratory support with mortality and intubation rates in acute respiratory failure: a systematic review and network meta-analysis, JOURNAL OF INTENSIVE CARE, 9(1), 20210412
  148. Post-extubation oxygenation strategies in acute respiratory failure: a systematic review and network meta-analysis, CRITICAL CARE, 25(1), 20210409
  149. Confounding Factors in a Study Investigating Mortality in Patients With Severe Hemoptysis, Crit Care Med, 49(4), 465-466, 20210401
  150. Hypothermia, Poorly Recognized by clinicians, is associated with Higher Mortality Among Critically Ill Patients with infections: A Retrospective Observational Study, JOURNAL OF INFECTION AND CHEMOTHERAPY, 27(3), 540-543, 20210301
  151. A machine-learning based approach to quantify fine crackles in the diagnosis of interstitial pneumonia A proof-of-concept study, MEDICINE, 100(7), 20210219
  152. A novel system that continuously visualizes and analyzes respiratory sounds to promptly evaluate upper airway abnormalities: a pilot study, J Clin Monit Comput, 20210118
  153. Occurrence and incidence rate of peripheral intravascular catheter-related phlebitis and complications in critically ill patients: a prospective cohort study (AMOR-VENUS study), JOURNAL OF INTENSIVE CARE, 9(1), 20210106
  154. Proteins produced by Streptococcus species in the lower respiratory tract can modify antiviral responses against influenza virus in respiratory epithelial cells, MICROBES AND INFECTION, 23(1), 20210101
  155. Japanese rapid/living recommendations on drug management for COVID-19, ACUTE MEDICINE & SURGERY, 8(1), 20210101
  156. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), Journal of Intensive Care, 8(1), 20210101
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  345. Combined short- and long-axis ultrasound-guided central venous catheterization is superior to conventional techniques: A cross-over randomized controlled manikin trial., PloS one, 12(12), 2017
  346. Comparison of the efficacy of three topical antiseptic solutions for the prevention of catheter colonization: a multicenter randomized controlled study., Critical care (London, England), 21(1), 2017
  347. Association between appropriate empiric antimicrobial therapy and mortality from bloodstream infections in the intensive care unit., Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 24(4), 2018
  348. Is Oxygenation Really an Intrinsic Predictive Factor of Mortality in Patients Undergoing Extracorporeal Life Support?, Critical care medicine, 46(2), 2018
  349. Confounders for interpreting the benefit of a biomarker-based strategy in early discontinuation of empirical antifungal therapy., Intensive care medicine, 44(3), 2018
  350. Regional Negative Pressure Pulmonary Edema with Pulmonary Thromboembolism., Internal medicine (Tokyo, Japan), 57(12), 2018
  351. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016)., Journal of intensive care, 6, 2018
  352. Accurate Quantification of Pleural Effusion and Cofactors Affecting Weaning Failure., Anesthesiology, 128(3), 2018
  353. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016)., Acute medicine & surgery, 5(1), 2018
  354. Potential confounders affecting the reintubation rate : Discussion on "Reconnection to mechanical ventilation for 1 h after a successful spontaneous breathing trial reduces reintubation in critically ill patients: a multicenter randomized controlled trial"., Intensive care medicine, 44(4), 2018
  355. Tracheal injury detected immediately after median sternotomy by inexperienced surgeons: two case reports., Journal of medical case reports, 12(1), 2018
  356. Ultrasound-guided central venous catheter placement in children: what is a really good practice?, Intensive care medicine, 44(4), 2018
  357. Target blood pressure for septic and vasodilatory shock: what is optimal?, Intensive care medicine, 44(4), 2018
  358. An emerging frontier in the treatment of acute exacerbation of idiopathic pulmonary fibrosis., Respiratory investigation, 56(2), 2018
  359. An outbreak of fluoroquinolone-resistant Pseudomonas aeruginosa ST357 harboring the exoU gene., Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 24(8), 2018
  360. Paediatric sequential organ failure assessment score (pSOFA): a plea for the world-wide collaboration for consensus., Intensive care medicine, 44(6), 2018
  361. Rapid-onset plasma leakage of extracorporeal oxygenation membranes possibly due to hyperbilirubinemia., Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 21(4), 2018
  362. Antimicrobials in the PICU: An Unresolved and Serious Matter., Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 19(6), 2018
  363. Does Dysphagia After Extubation Really Increase Mortality?, Critical care medicine, 46(7), 2018
  364. Out-of-bed mobilization of patients undergoing mechanical ventilation with orotracheal tubes: A survey study., Journal of critical care, 47, 2018
  365. Comparison of extracorporeal membrane oxygenation outcome for influenza-associated acute respiratory failure in Japan between 2009 and 2016., Journal of intensive care, 6, 2018
  366. Sera from Septic Patients Contain the Inhibiting Activity of the Extracellular ATP-Dependent Inflammasome Pathway., The Tohoku journal of experimental medicine, 245(3), 2018
  367. A Therapeutic Strategy for All Pneumonia Patients: A 3-Year Prospective Multicenter Cohort Study Using Risk Factors for Multidrug-resistant Pathogens to Select Initial Empiric Therapy., Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 68(7), 2019
  368. Clinical outcomes after initial treatment of methicillin-resistant Staphylococcus aureus infections., Infection and drug resistance, 11, 2018
  369. Should We Abandon Airway Pressure Release Ventilation in Pediatric Acute Respiratory Distress Syndrome?, American journal of respiratory and critical care medicine, 198(11), 2018
  370. Transient severe distributive shock due to early dumping syndrome: a case report., Journal of medical case reports, 12(1), 2018
  371. Implementation of an empirical antimicrobial protocol in a critical care setting: A single-center retrospective observational cohort study in bacteremic patients., Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 24(12), 2018
  372. Comparing Combined Short-Axis and Long-Axis Ultrasound-Guided Central Venous Catheterization With Conventional Short-Axis Out-of-Plane Approaches., Journal of cardiothoracic and vascular anesthesia, 33(4), 2019
  373. Focusing on Risk Factors of Cardiac Arrest During Intubation in ICU Again., Critical care medicine, 46(11), 2018
  374. A survey on infection control in emergency departments in Japan., Acute medicine & surgery, 5(4), 2018
  375. Conducting trials on corticosteroid dosing for respiratory failure in the last paradise., Journal of intensive care, 6, 2018
  376. The western Japan chaotic rainstorm disaster: a brief report from Hiroshima., Journal of intensive care, 6, 2018
  377. Dynamic Needle Tip Positioning for Ultrasound-Guided Arterial Catheterization in Infants and Small Children With Deep Arteries: A Randomized Controlled Trial., Journal of cardiothoracic and vascular anesthesia, 33(7), 2019
  378. Potential confounders for the effect of high-flow nasal cannula oxygen therapy., Critical care (London, England), 23(1), 2019
  379. Ventilator-associated events: prevalence and mortality in Japan., Journal of thoracic disease, 10(12), 2018
  380. High serum potassium level is associated with successful electrical cardioversion for new-onset atrial fibrillation in the intensive care unit: A retrospective observational study., Anaesthesia and intensive care, 47(1), 2019
  381. Comparison of three video laryngoscopes and direct laryngoscopy for emergency endotracheal intubation: a retrospective cohort study., BMJ open, 9(3), 2019
  382. ICU staffing models and patient outcomes., Journal of intensive care, 7, 2019
  383. Combined Approach Versus 2 Conventional Approaches in Ultrasound-Guided Central Venous Catheterization: A Randomized Controlled Trial., Journal of cardiothoracic and vascular anesthesia, 33(11), 2019
  384. Dynamic Needle Tip Positioning for Ultrasound-Guided Placement of a Peripherally Inserted Central Catheter in Pediatric Patients., Journal of cardiothoracic and vascular anesthesia, 34(1), 2020
  385. Impact of inappropriate empiric antimicrobial therapy on mortality in pediatric patients with bloodstream infection: a retrospective observational study., Journal of chemotherapy (Florence, Italy), 31(7-8), 2019
  386. Is lung ultrasonography really useful for diagnosing weaning-induced pulmonary oedema?, Intensive care medicine, 45(9), 2019
  387. Superiority of Dynamic Needle Tip Positioning for Ultrasound-Guided Peripheral Venous Catheterization in Patients Younger Than 2 Years Old: A Randomized Controlled Trial., Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 20(9), 2019
  388. Decreased intracellular histamine concentration and basophil activation in anaphylaxis., Allergology international : official journal of the Japanese Society of Allergology, 69(1), 2020
  389. Comparison of video and conventional laryngoscopes for simulated difficult emergency tracheal intubations in the presence of liquids in the airway., PloS one, 14(7), 2019
  390. Ultrasonographic Detection of Micro-Bubbles in the Right Atrium to Confirm Peripheral Venous Catheter Position in Children., Critical care medicine, 47(10), 2019
  391. Does nasal high-flow preoxygenation really reduce intubation-related adverse events?, Intensive care medicine, 46(3), 2020
  392. Confounding factors for the effect of misdiagnosis of site of infection on in-hospital mortality., Critical care (London, England), 23(1), 2019
  393. Ceftolozane-tazobactam versus meropenem for treatment of nosocomial pneumonia (ASPECT-NP): a randomised, controlled, double-blind, phase 3, non-inferiority trial., The Lancet. Infectious diseases, 19(12), 2019
  394. Early Extubation for Infant Cardiac Surgery Supported by Dexmedetomidine Use., Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 20(10), 2019
  395. Effect of pulsed xenon ultraviolet disinfection on methicillin-resistant Staphylococcus aureus contamination of high-touch surfaces in a Japanese hospital., American journal of infection control, 48(2), 2020
  396. Determination of the Appropriate Depth of Cuffed Endotracheal Tubes in Pediatric Intensive Care., Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 20(11), 2019
  397. Unique patterns of lower respiratory tract microbiota are associated with inflammation and hospital mortality in acute respiratory distress syndrome., Respiratory research, 20(1), 2019
  398. The Volume of Pediatric Blood Culture., The Pediatric infectious disease journal, 38(12), 2019
  399. Baseline High-Resolution CT Findings Predict Acute Exacerbation of Idiopathic Pulmonary Fibrosis: German and Japanese Cohort Study., Journal of clinical medicine, 8(12), 2019
  400. Neurally adjusted ventilatory assist mitigates ventilator-induced diaphragm injury in rabbits., Respiratory research, 20(1), 2019
  401. Retrospective immunohistological study of autopsied lungs in patients with acute exacerbation of interstitial pneumonia managed with extracorporeal membrane oxygenation., Journal of thoracic disease, 11(11), 2019
  402. Potential Confounders for Applying a Novel Sepsis Care Quality Improvement Program., Critical care medicine, 48(2), 2020
  403. Successful anesthetic management during abdominal wall-lifting laparoscopic cholecystectomy in a patient with hereditary angioedema., JA clinical reports, 4(1), 2018
  404. Successful treatment of extensive spinal epidural abscess with fluoroscopy-guided percutaneous drainage: a case report., JA clinical reports, 6(1), 2020
  405. A Ruptured Mediastinal Bronchial Artery Aneurysm Treated with Urgent Thoracic Endovascular Aortic Repair., Internal medicine (Tokyo, Japan), 59(10), 2020
  406. Is Broad-Spectrum Antimicrobial Prophylaxis Ideal for Open-Chest Management?, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 21(3), 2020
  407. Further Investigation of Diagnostic Errors in Critically Ill Medical Patients., Critical care medicine, 48(5), 2020
  408. Impact of host- and early treatment-related factors on mortality in ICU patients with candidemia: a bicentric retrospective observational study., Journal of intensive care, 8, 2020
  409. Save the ICU and save lives during the COVID-19 pandemic., Journal of intensive care, 8, 2020
  410. Long-Axis In-Plane Approach Versus Short-Axis Out-of-Plane Approach for Ultrasound-Guided Central Venous Catheterization in Pediatric Patients: A Randomized Controlled Trial., Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 21(11), 2020
  411. Esophageal pressure and potential confounders for evaluating patient-ventilator asynchrony., Journal of critical care, 60, 2020
  412. Prognosis of pathogen-proven acute respiratory distress syndrome diagnosed from a protocol that includes bronchoalveolar lavage: a retrospective observational study., Journal of intensive care, 8, 2020
  413. Early PaCO2 Changes after Initiating Extracorporeal Membrane Oxygenation: Considerations for Future Research., American journal of respiratory and critical care medicine, 202(11), 2020
  414. Early Tracheostomy in Brain Injury: More Details Are Needed for Seeking Best Practice., Critical care medicine, 48(10), 2020
  415. Microglial translocator protein and stressor-related disorder., Neurochemistry international, 140, 2020
  416. Ultrasound-guided peripheral vascular catheterization in pediatric patients: a narrative review., Critical care (London, England), 24(1), 2020
  417. Better Management of Delirium by Family Members., Critical care medicine, 48(11), 2020
  418. Proteins produced by Streptococcus species in the lower respiratory tract can modify antiviral responses against influenza virus in respiratory epithelial cells., Microbes and infection, 23(1), 2021
  419. Prolonged versus intermittent β-lactam antibiotics intravenous infusion strategy in sepsis or septic shock patients: a systematic review with meta-analysis and trial sequential analysis of randomized trials., Journal of intensive care, 8, 2020
  420. Frequency and Risk Factors for Reverse Triggering in Pediatric Acute Respiratory Distress Syndrome during Synchronized Intermittent Mandatory Ventilation., Annals of the American Thoracic Society, 18(5), 2021
  421. Bent peripheral venous catheter inserted using ultrasound-guided dynamic needle tip positioning., The journal of vascular access, 23(1), 2022
  422. Pharmacological and Genetic Inhibition of Translocator Protein 18 kDa Ameliorated Neuroinflammation in Murine Endotoxemia Model., Shock (Augusta, Ga.), 56(1), 2021
  423. Ultrasound-guided dynamic needle tip positioning versus conventional palpation approach for catheterisation of posterior tibial or dorsalis pedis artery in infants and small children., British journal of anaesthesia, 126(4), 2021
  424. Hypothermia, Poorly Recognized by clinicians, is associated with Higher Mortality Among Critically Ill Patients with infections: A Retrospective Observational Study., Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 27(3), 2021
  425. Occurrence and incidence rate of peripheral intravascular catheter-related phlebitis and complications in critically ill patients: a prospective cohort study (AMOR-VENUS study)., Journal of intensive care, 9(1), 2021
  426. A novel system that continuously visualizes and analyzes respiratory sounds to promptly evaluate upper airway abnormalities: a pilot study., Journal of clinical monitoring and computing, 36(1), 2022
  427. Combining pulsed xenon ultraviolet disinfection with terminal manual cleaning helps reduce the acquisition rate of methicillin-resistant Staphylococcus aureus., American journal of infection control, 49(8), 2021
  428. A machine-learning based approach to quantify fine crackles in the diagnosis of interstitial pneumonia: A proof-of-concept study., Medicine, 100(7), 2021
  429. Pediatric Fulminant Myocarditis in Japan: A Retrospective Nationwide Database Study of Hospital Volume, Management Practices, and Mortality., Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 22(7), 2021
  430. Confounding Factors in a Study Investigating Mortality in Patients With Severe Hemoptysis., Critical care medicine, 49(4), 2021
  431. Unclear Benefit of Early Tracheostomy In Patients With Coronavirus Disease 2019., Critical care medicine, 49(7), 2021
  432. Post-extubation oxygenation strategies in acute respiratory failure: a systematic review and network meta-analysis., Critical care (London, England), 25(1), 2021
  433. Association of noninvasive respiratory support with mortality and intubation rates in acute respiratory failure: a systematic review and network meta-analysis., Journal of intensive care, 9(1), 2021
  434. Prevalence of rapid response systems in small hospitals: A questionnaire survey., Medicine, 100(23), 2021
  435. Japanese rapid/living recommendations on drug management for COVID-19., Acute medicine & surgery, 8(1), 2021
  436. Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial., Critical care (London, England), 25(1), 2021
  437. Patient-ventilator asynchrony, impact on clinical outcomes and effectiveness of interventions: a systematic review and meta-analysis., Journal of intensive care, 9(1), 2021
  438. Effect of region-wide use of prehospital stroke triage scale on management of patients with acute stroke., Journal of neurointerventional surgery, 14(7), 2022
  439. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)., Journal of intensive care, 9(1), 2021
  440. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)., Acute medicine & surgery, 8(1), 2021
  441. The Association between Wearing a Mask and COVID-19., International journal of environmental research and public health, 18(17), 2021
  442. The right care at the right place: Significance of intensive care units for critically ill patients., The Lancet regional health. Western Pacific, 13, 2021
  443. Trends in the incidence and outcome of sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group., Critical care (London, England), 25(1), 2021
  444. Duration of infectious virus shedding in patients with severe coronavirus disease 2019 who required mechanical ventilation., Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 28(1), 2022
  445. Did the Effect of the Guidelines eVAPorate? The Need for Improved Antimicrobial Stewardship Continues., Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 22(10), 2021
  446. Identification of Aggravation-Predicting Gene Polymorphisms in Coronavirus Disease 2019 Patients Using a Candidate Gene Approach Associated With Multiple Phase Pathogenesis: A Study in a Japanese City of 1 Million People., Critical care explorations, 3(11), 2021
  447. Short- versus prolonged-course antibiotic therapy for sepsis or infectious diseases in critically ill adults: a systematic review and meta-analysis., Infectious diseases (London, England), 54(3), 2022
  448. Japanese rapid/living recommendations on drug management for COVID-19: updated guidelines (September 2021)., Acute medicine & surgery, 8(1), 2021
  449. Differential Effectiveness of Hypothermic Targeted Temperature Management According to the Severity of Post-Cardiac Arrest Syndrome., Journal of clinical medicine, 10(23), 2021
  450. Case Report: Emphysematous Pyelonephritis With a Congenital Giant Ureterocele., Frontiers in pediatrics, 9, 2021
  451. Concerning the Association Between Delayed Administration of Antibiotics and Mortality in Patients With Suspected Sepsis., Critical care medicine, 50(1), 2022
  452. Potential Confounders in Evaluating the Impact of Hyperoxia on Neurological Outcomes in Patients Receiving Extracorporeal Membrane Oxygenation., Critical care medicine, 50(1), 2022
  453. Real-time assessment of swallowing sound using an electronic stethoscope and an artificial intelligence system., Clinical and experimental dental research, 8(1), 2022
  454. Clinical and microbiological outcomes, by causative pathogen, in the ASPECT-NP randomized, controlled, Phase 3 trial comparing ceftolozane/tazobactam and meropenem for treatment of hospital-acquired/ventilator-associated bacterial pneumonia., The Journal of antimicrobial chemotherapy, 77(4), 2022
  455. Deep sedation predicts pressure injury in patients admitted to intensive care units., Nursing in critical care, 27(6), 2022
  456. Regional respiratory sound abnormalities in pneumothorax and pleural effusion detected via respiratory sound visualization and quantification: case report., Journal of clinical monitoring and computing, 36(6), 2022
  457. Neutralizing Type I Interferon Autoantibodies in Japanese Patients With Severe COVID-19., Research square, 2022
  458. Risk factors for peripheral intravascular catheter-related phlebitis in critically ill patients: analysis of 3429 catheters from 23 Japanese intensive care units., Annals of intensive care, 12(1), 2022
  459. Changes in pediatric intensive care unit cases due to the novel coronavirus., Pediatrics international : official journal of the Japan Pediatric Society, 64(1), 2022
  460. Resource-rich Intensive Care Units Improve Health-What Is Next?, JMA journal, 5(2), 2022
  461. The Current and Future State of Pediatric Sepsis Definitions: An International Survey., Pediatrics, 149(6), 2022
  462. Prediction of Prehospital Change of the Cardiac Rhythm From Nonshockable to Shockable in Out-of-Hospital Patients With Cardiac Arrest: A Post Hoc Analysis of a Nationwide, Multicenter, Prospective Registry., Journal of the American Heart Association, 11(12), 2022
  463. Quantification of respiratory sounds by a continuous monitoring system can be used to predict complications after extubation: a pilot study., Journal of clinical monitoring and computing, 37(1), 2023
  464. ARDS clinical practice guideline 2021., Respiratory investigation, 60(4), 2022
  465. Neutralizing Type I Interferon Autoantibodies in Japanese Patients with Severe COVID-19., Journal of clinical immunology, 42(7), 2022
  466. ARDS Clinical Practice Guideline 2021., Journal of intensive care, 10(1), 2022
  467. Temporal trends of medical cost and cost-effectiveness in sepsis patients: a Japanese nationwide medical claims database., Journal of intensive care, 10(1), 2022
  468. Controversial Efficacy of Prone-Positioning for Patients With Severe Acute Respiratory Distress Syndrome Undergoing Venous-Venous Extracorporeal Membrane Oxygenation., Critical care medicine, 50(9), 2022
  469. Alarming of Severe Respiratory Failure Requiring ECMO Caused by the SARS-CoV-2 Omicron Variant., JMA journal, 5(3), 2022
  470. Combined short-axis out-of-plane and long-axis in-plane approach versus long-axis in-plane approach for ultrasound-guided central venous catheterization in infants and small children: A randomized controlled trial., PloS one, 17(9), 2022
  471. Incidence of catheter-related bloodstream infections following ultrasound-guided central venous catheterization: a systematic review and meta-analysis., BMC infectious diseases, 22(1), 2022
  472. The research environment of critical care in three Asian countries: A cross-sectional questionnaire survey., Frontiers in medicine, 9, 2022
  473. Japanese rapid/living recommendations on drug management for COVID-19: updated guidelines (July 2022)., Acute medicine & surgery, 9(1), 2022
  474. A burden of fluid, sodium, and chloride due to intravenous fluid therapy in patients with respiratory support: a post-hoc analysis of a multicenter cohort study., Annals of intensive care, 12(1), 2022
  475. Effect of wearing a surgical mask on short-term pulmonary gas exchange in patients immediately after anaesthesia., Indian journal of anaesthesia, 66(8), 2022
  476. Short- versus long-course antibiotic therapy for sepsis: a post hoc analysis of the nationwide cohort study., Journal of intensive care, 10(1), 2022
  477. Trends in survival during the pandemic in patients with critical COVID-19 receiving mechanical ventilation with or without ECMO: analysis of the Japanese national registry data., Critical care (London, England), 26(1), 2022
  478. Unexpected cholinergic crisis caused by distigmine bromide: A case report., Medicine, 101(47), 2022
  479. An algorithm for PCT-guided antimicrobial therapy: a consensus statement by Japanese experts., Clinical chemistry and laboratory medicine, 61(3), 2023
  480. Risk factors for peripheral venous catheter-related phlebitis stratified by body mass index in critically ill patients: A post-hoc analysis of the AMOR-VENUS study., Frontiers in medicine, 9, 2022
  481. A study of the risk factors for phlebitis in patients stratified using the acute physiology and chronic health evaluation II score and admitted to the intensive care unit: A post hoc analysis of the AMOR-VENUS study., Frontiers in medicine, 9, 2022
  482. Mortality analysis among sepsis patients in and out of intensive care units using the Japanese nationwide medical claims database: a study by the Japan Sepsis Alliance study group., Journal of intensive care, 11(1), 2023
  483. GENETIC DELETION OF TRANSLOCATOR PROTEIN EXACERBATES POST-SEPSIS SYNDROME WITH ACTIVATION OF THE C1Q PATHWAY IN SEPTIC MOUSE MODEL., Shock (Augusta, Ga.), 59(1), 2023
  484. Ultrasound-guided short-axis out-of-plane approach with or without dynamic needle tip positioning for arterial line insertion in children: A systematic review with network meta-analysis., Anaesthesia, critical care & pain medicine, 42(3), 2023
  485. Impact of frailty on long-term mortality in older patients receiving intensive care via the emergency department., Scientific reports, 13(1), 2023
  486. Temperature management using an intervascular cooling device for a COVID-19 patient with refractory hyperthermia., Clinical case reports, 11(4), 2023
  487. Lethal Interstitial Lung Disease Associated with a Gain-of-Function Mutation in IFIH1., Journal of clinical immunology, 43(6), 2023
  488. Characteristics of the pulmonary opacities on chest CT associated with difficulty in short-term liberation from veno-venous ECMO in patients with severe ARDS., Respiratory research, 24(1), 2023
  489. Predictive Accuracy of the ROX Index for Re-Intubation in Mechanically Ventilated Patients With COVID-19., Respiratory care, 68(8), 2023
  490. Lung Abscess and Pyothorax in Critically Ill COVID-19 Patients: A Single-Center Retrospective Study., Critical care explorations, 5(5), 2023
  491. Is Pneumomediastinum Really an Independent Prognostic Factor for COVID-19 Pneumonia?, Critical care medicine, 51(6), 2023
  492. Ultrasound-Guided Short-Axis Out-of-Plane Approach With or Without Dynamic Needle-Tip Positioning for Peripheral Venous Catheterization in Pediatric Patients: A Systematic Review With Network Meta-Analysis., Journal of cardiothoracic and vascular anesthesia, 37(10), 2023
  493. Impact of the failure of initial insertion of a peripheral intravascular catheter on the development of adverse events in patients admitted to the intensive care unit from the emergency room: A post hoc analysis of the AMOR-VENUS study., Acute medicine & surgery, 10(1), 2023
  494. Controversial Efficacy of Early Timing of Prone Positioning for Severe Acute Respiratory Distress Syndrome During Venovenous Extracorporeal Membrane Oxygenation., Critical care medicine, 51(7), 2023
  495. Use of a laryngeal tube for sialolithotomy in a pediatric patient with left vocal cord paralysis: a case report., JA clinical reports, 9(1), 2023
  496. Beyond the unthinkable: Are we prepared for rare disasters?, Anaesthesia, critical care & pain medicine, 42(4), 2023
  497. Efficacy of perioperative prophylactic administration of corticosteroids in pediatric cardiac surgeries using cardiopulmonary bypass: a systematic review with meta-analysis., Anaesthesia, critical care & pain medicine, 42(6), 2023
  498. ICU Liberation Bundles and The Legend of Three Arrows., Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 24(8), 2023
  499. Comparison of radial, dorsalis pedis, and posterior tibial arteries for ultrasound-guided arterial catheterisation with dynamic needle tip positioning in paediatric patients: a randomised controlled trial., British journal of anaesthesia, 131(4), 2023
  500. Multisystem inflammatory syndrome in adults with COVID-19 requiring mechanical ventilation: A retrospective cohort study., Acute medicine & surgery, 10(1), 2023
  501. Survey of pediatric cardiovascular anesthesia in Japan., Journal of anesthesia, 38(2), 2024
  502. High versus low positive end-expiratory pressure setting in patients receiving veno-venous extracorporeal membrane oxygenation support for severe acute respiratory distress syndrome: study protocol for the multicentre, randomised ExPress SAVER Trial., BMJ open, 13(10), 2023
  503. Usefulness of Quantification and Serial Monitoring of Fine Crackles for Early Detection of Treatment-related Lung Injury: A Report of Two Cases., Internal medicine (Tokyo, Japan), 63(12), 2024
  504. Usefulness of new acoustic respiratory sound monitoring with artificial intelligence for upper airway assessment in obese patients during monitored anesthesia care., The journal of medical investigation : JMI, 70(3.4), 2023
  505. New acoustic monitoring system quantifying aspiration risk during monitored anaesthesia care., Scientific reports, 13(1), 2023
  506. A Successful Prevention of Reintubation Using the Mechanical Insufflation-Exsufflation in a Critically Ill Patient With Impaired Airway Mucus Expectoration: A Case Report., Cureus, 15(10), 2023
  507. Association between hospital volume and in-hospital mortality in pediatric severe traumatic brain injury: a nationwide retrospective observational study in Japan., Journal of neurosurgery. Pediatrics, 33(2), 2024
  508. Efficiency and workload reduction of semi-automated citation screening software for creating clinical practice guidelines: a prospective observational study., Journal of epidemiology, 2023
  509. Prediction of the neurological outcomes post-cardiac arrest: A prospective validation of the CAST and rCAST., The American journal of emergency medicine, 75, 2024
  510. Association between hospital spending and in-hospital mortality of patients with sepsis based on a Japanese nationwide medical claims database study., Heliyon, 10(1), 2024
  511. Carbapenem vs. non-carbapenem antibiotics for ventilator-associated pneumonia: A systematic review with meta-analysis., Respiratory investigation, 62(2), 2024
  512. Time to Reexamine the Definition of Sepsis?, Critical care medicine, 52(2), 2024
  513. Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry., Journal of intensive care, 12(1), 2024
  514. Association between regional critical care capacity and the incidence of invasive mechanical ventilation for coronavirus disease 2019: a population-based cohort study., Journal of intensive care, 12(1), 2024
  515. Epidemiology and patterns of empiric antimicrobial therapy practice in patients with community-onset sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group., IJID regions, 10, 2024
  516. External validation of the rCAST for patients after in-hospital cardiac arrest: a multicenter retrospective observational study., Scientific reports, 14(1), 2024
  517. Bacterial profiles detected in ventilator-associated pneumonia in Japan: A systematic review., Respiratory investigation, 62(3), 2024
  518. Differences in Pathophysiology and Treatment Efficacy Based on Heterogeneous Out-of-Hospital Cardiac Arrest., Medicina (Kaunas, Lithuania), 60(3), 2024
  519. The Current Discussion Regarding End-of-Life Care for Patients with Out-of-Hospital Cardiac Arrest with Initial Non-Shockable Rhythm: A Narrative Review., Medicina (Kaunas, Lithuania), 60(4), 2024
  520. Genomic characterization of Staphylococcus aureus isolated from patients admitted to intensive care units of a tertiary care hospital: epidemiological risk of nasal carriage of virulent clone during admission., Microbiology spectrum, 12(6), 202406
  521. Hypercalcemic Crisis Complicated With Acute Respiratory Distress Syndrome Due to Hot Spring Drowning: A Case Report., Cureus, 16(4), 2024
  522. Incidence and mortality of community-acquired and nosocomial infections in Japan: a nationwide medical claims database study., BMC infectious diseases, 24(1), 202405
  523. Hospital and regional variations in intensive care unit admission for patients with invasive mechanical ventilation., Journal of intensive care, 12(1), 21, 202406
  524. No improvement in mortality among critically ill patients with carbapenems as initial empirical therapy and more detection of multi-drug resistant pathogens associated with longer use: a post hoc analysis of a prospective cohort study., Microbiology spectrum, 12(7), 202407

Publications such as books

  1. 2016, Critical Care UPDATE, 2016, Single work, 日本語
  2. 2015, Critical Care UPDATE, 2015, Single work, 日本語
  3. 2015, Critical Care UPDATE, 2015, Single work, 日本語

Invited Lecture, Oral Presentation, Poster Presentation

  1. Crucial elements of constructing an organizational framework in J-SSCG 2024 for a sustainable future, Oami T, Yamakawa K, Shime N, Nakada T, Yatabe T, Aoki Y, Inoue Y, Iba T, Ogura H, Kawai Y, Kawaguchi A, Kawasaki T, Kondo Y, Sakuraya M, Taito S, Doi K, Hashimoto H, Hara Y, Fukuda T, Matsushima A, Egi M, Kushimoto S, The 3rd Joint Scientific Congress of TSCCM, TSECCM, and JSICM, 2024/03/16, Without Invitation, Japanese
  2. Analysis of autopsy findings in patients with acute respiratory failure supported on V-V ECMO., Kida Y, Ohshimo S, Kyo M, Shimatani T, Hirohashi N, Shime N., The 16th Joint Scientific Congress of the Korean Society of Critical Care Medicine (KSCCM) and Japanese Society of Intensive Care Medicine (JSICM), 2016/04/22, Without Invitation, English, Seoul
  3. Successful use of VAV ECMO in a patient with respiratory failure complicated by myocarditis., Kyo M, Ohshimo S, Kida Y, Shimatanin T, Hirohashi N, Shime N., he 16th Joint Scientific Congress of the Korean Society of Critical Care Medicine (KSCCM) and Japanese Society of Intensive Care Medicine (JSICM), 2016/04/22, Without Invitation, English, Seoul
  4. Optimal Volume and Substance in Intraesophageal Balloon Catheter for Esophageal Pressure Measurement., Shimatanin T, Kida Y, Hirohashi N, Shime N., The 16th Joint Scientific Congress of the Korean Society of Critical Care Medicine (KSCCM) and Japanese Society of Intensive Care Medicine (JSICM)., 2016/04/22, Without Invitation, English, Seoul
  5. The experiences of physical therapy for the patients with veno-venous extracorporeal membrane oxygenation in Hiroshima university hospital., Sarada K, Taito S, Sekikawa K, Ohshimo S, Ota K, Hirohashi N, Ueda K, Mikami Y, Kimura H, Shime N, Ito Y., 13th Asian Confederation of Physical Therapy Congress 2016, 2016/09/10, Without Invitation, English, Kuala Lumpur
  6. Protein expression profile in acute exacerbation of interstitial pneumonia supported on V-V ECMO., Kida Y, Ohshimo S, Kyo M, AMATYA J. Vishwa, Takeshima Y, Shime N., SCCM's 46th Critical Care Congress, 2017/01/21, Without Invitation, English, Honolulu
  7. Validation of qSOFA criteria for sepsis., Kyo M, Ohshimo S, Kida Y, Shime N., SCCM's 46th Critical Care Congress, 2017/01/21, Without Invitation, English, Honolulu
  8. Helicobacter pylori as a risk factor for acute exacerbation in idiopathic pulmonary fibrosis., Ohshimo S, Nishi H, Horimasu Y, Iwamoto H, Hamada H, Hattori N, Kohno N, Bonella F, Guzman J, Costabel U, Shime N., American Thoracic Society International Conference 2017, 2017/05/19, Without Invitation, English, Washington DC
  9. Comparison of video-laryngoscope and conventional Macintosh laryngoscope for simulated emergency tracheal intubation by pre-hospital emergency care providers with copious vomiting or bleeding in oral cavity., Suzuki K, Kusumoki S, Sadamori T, Tanabe Y, Itai J, Shime N., The European Anaesthesiology Congress 2017, 2017/06/03, Without Invitation, English, Switzerland
  10. Impact of inappropriate empiric antibiotic therapy on the mortality inpeadiatric patients with bloodstream infections., Kyo M, Ohshimo S, Kosaka T, Fujita N, Shime N., infections., 2017/11/24, Without Invitation, English, Taiwan
  11. Real-time guidance or prelocation using ultrasound for pediatric central venous catheterization; a systematic review and network meta-analysis., Hosokawa K, Shime N, Kyo M, Iwasaki Y, Kida Y, 38th International Symposium on Intensive Care and Emergency Medicine,, 2018/03/20, Without Invitation, English, Blrusseles
  12. Bronchoalveolar lavage as diagnostic and prognostic tool in acute respiratory failure., Iwasaki Y, Hosokawa K, Ohshimo S, Shime N, 38th International Symposium on Intensive Care and Emergency Medicine, 2018/03/20, Without Invitation, English, Blrusseles
  13. Modified GAP stage as a predictor of acute exacerbation in idiopathic pulmonary fibrosis., Ohshimo S, Kida Y, Kyo M, Hosokawa K, Horimasu Y, Miyamoto S, Iwamoto H, Hamada H, Hattori N, Bonella F, Guzman J, Costabel U, Shime N., ERS INTERNATIONAL CONGRESS 2018, 2018/09/15, Without Invitation, English, Paris
  14. Imbalance in the oral bacterial flora as a risk factor of acute exacerbation in idiopathic pulmonary fibrosis., Ohshimo S, Nishi H, Hosokawa K, Horimasu Y, Miyamoto S, Iwamoto H, Hamada H, Kawaguch H, Bonella F, Guzman J, Costabel U, Hattori N, Shime N., European Respiratory Society International Congress 2019, 2019/09/28, Without Invitation, English, Madrid
  15. Different aspects of diffuse lung diseases in intensive care unit and respiratory department., Ohshimo S, Kida Y, Hirano C, Kikutani K, Kyo M, Inagawa T, Ota K, Hosokawa K, Yamaguchi K, Horimasu Y, Miyamoto S, Iwamoto H, Fujitaka K, Hamada H, Bonella F, Guzman J, Costabel U, Hattori N, Shime N., Joint Conference of International Conference on Sarcoidosis and Interstitial Lung Diseases 2019 (WASOG) and The 39th Annual Meeting of Japan Society of Sarcoidosis and other Granulomatous Disorders, 2019/10/09, Without Invitation, English, Yokohama
  16. Emergency calls of cardiac arrest patients with do-not-attempt-resuscitation orders in Hiroshima, Japan., Hosokawa K, Yamaga S, Shime N., European Society for Emergency Medicine Congress 2019, 2019/10/12, Without Invitation, English, Prague
  17. Clinical features, management, and factors associated with mortality in pediatric patients with acute myocarditis: an analysis of a Japanese administrative database., Ohki S, Hosokawa K, Matsuoka M, Tomioka S, Matsuda S, Shime N., European Society for Emergency Medicine Congress 2019, 2019/10/12, Without Invitation, English, Prague
  18. Lower respiratory tract microbiota is associated with inflammation and hospital mortality in acute respiratory distress syndrome: a pilot study., Kyo M, Nishioka K, Nakaya T, Kida Y, Tanabe Y, Ohshimo S, Shime N., Critical Care Canada Forum 2019, 2019/11/11, Without Invitation, English, Toronto
  19. Ten years experience of respiratory ECMO in Japan., Ohshimo S, Abe R, Araki Y, Fujino Y, Hara Y, Hattori N, Ikeyama T, Masuno T, Oyama K, Shimizu K, Suzuki H, Suzuki K, Takeuchi I, Hirose H, Shime N, Takeda S., The 9th EuroELSO Congress 2020, The 9th EuroELSO Congress 2020, 2020/05/06, Without Invitation, English
  20. Difference between pathogenic and inhibitory bacterial florae is associated with acute exacerbation of idiopathic pulmonary fibrosis., Ohshimo S, Nishi H, Yamaguchi K, Horimasu Y, Masuda T, Miyamoto S, Iwamoto H, Fujitaka K, Hamada H, Kawaguchi H, Bonella F, Guzman J, Costabel, Hattori N, Shime N., European Respiratory Society International Congress 2020, 2020/09/05, Without Invitation, English
  21. Prognostic analysis of patients with severe COVID-19 receiving mechanical ventilation with or without ECMO: Analysis of Japan national registry., Ohshimo S, Keibun Liu, Takayuki Ogura, Yoshiaki Iwashita, Shigeki Kushimoto, Nobuaki Shime, Satoru Hashimoto, Shinhiro Takeda; on behalf of Japan ECMOnet, The 1st Joint Scientific Congress of TSCCM, TSECCM, and JSICM, 2021/03/18, Without Invitation, English
  22. Mechanically-ventilated COVID-19 cases: A single, quarterly-institute, one-year experience., Shime N, The 41st KSCCM・ACCC 2021, 2021/05/01, Without Invitation, English
  23. Adrenal crisis secondary to acute alcohol intoxication., Ishii J, Ohshimo S, Shime N., The 41st KSCCM・ACCC 2021, 2021/05/01, Without Invitation, English
  24. Descriptive Study for Critically-3 COVID-19 Patients : A Single-Institute, One and Half-Year Experience., Shime N., SECC-Best of SCCM Congress 2021 Taipei, 2021/12/18, Without Invitation, English
  25. Quantification of respiratory sounds by continuous monitoring system can be used to predict complications after extubation: A pilot study., Kikutani K, Ohshimo S, Sadamori T, Ohki S, Giga H, Ishii J, Miyoshi H, Ota K, Shime N., The 22nd KSCCM-JSICM Joint Congress, 2022/03/18, Without Invitation, English
  26. Diferences in the impact of hypothermia on mortality between pediatric and adult trauma patients., Kurata N, Nishikimi M, Ohshimo S, Shime N., ESICM 37th Annual Congress. 2024, 2024/10/05, Without Invitation, English, Barcelona
  27. Risk factors for mortality in radiological sub‑phenotypes of severe ARDS patients on veno‑venous ecmo: insights from the J‑CARVE registry., Hadama K, Nishikimi M, Ohshimo S, Shime N., ESICM 37th Annual Congress. 2024, 2024/10/05, Without Invitation, English, Barcelona
  28. Novel subtypes and diferential response to muscle relaxants in patients with severe ARDS requiring V‑V ECMO: potential for individualized management during V‑V ECMO., Nishikimi M, Ohshimo S, Shime N., ESICM 37th Annual Congress. 2024, 2024/10/05, Without Invitation, English, Barcelona
  29. Questionnaire survey of physicians and the general public regarding the time required to perform cardiopulmonary resuscitation., Tanabe Y, Maeda S, Ishikawa E, Shime N., ISQua's 40th International Conference 2024, 2024/09/24, Without Invitation, English, Istanbul
  30. TRANEXAMIC ACID IN PEDIATRIC TRAUMATIC BRAIN INJURY: A MULTICENTER RETROSPECTIVE OBSERVATIONAL STUDY., Utsumi S, Ohki S, Amagasa S, Ohshimo S, Shime N., EURO ASIA 2024, 2024/09/24, Without Invitation, English, Bengaluru
  31. Effect of Hospital Arrival Time on Mortality Rate in Pediatric Patients With Severe Trauma: A Nationwide Database Study in Japan., Ohki S, Matsuo R, Nishikimi M, Ohshimo S, Shime N., AHA Scientific Sessions 2023, 2023/11/11, Without Invitation, English, Philadelphia
  32. Is Effect Size of Targeted Temperature Management Different for Pediatric Post-Cardiac Arrest Syndrome According to the Severity?, Namba T, Ohshimo S, Nishikimi M, Miyoshi H, Masuka Y, Shime N, AHA Scientific Sessions 2023. 2023.11.11-12,, 2023/11/11, Without Invitation, English, Philadelphia
  33. Differences in Mid-Term Neurological Changes From 30 to 90 Days According to Age; is Plasticity Following Brain Injury After Cardiac Arrest Observed in Children or Young Adults?, Miyoshi H, Nishikimi M, Masuka Y, Namba T, Ohshimo S Shime N., AHA Scientific Sessions 2023, 2023/11/11, Without Invitation, English, Philadelphia
  34. A Novel Machine Learning Approach for Identifying Subgroups With Differential Responses to Amiodarone in Patients With Cardiac Arrest With Shockable Rhythm., Nishikimi M, Matsui S, Shime N., AHA Scientific Sessions 2023, 2023/11/11, Without Invitation, English, Philadelphia
  35. Novel staging system (AVEX stage) predicts survival in patients with severe COVID‑19 who received ECMO: analysis of the Japanese national registry., Ohshimo S, Takaki S, Shime N, Liu K, Ogura T, Shimizu K, Kushimoto S, Hashimoto S, Fujino Y, Takeda S., ESICM 36th annual congress, 2023/10/21, Without Invitation, English, Milan
  36. Low serum zonulin concentrations are associated with an unfavorable outcome in patients with sepsis., Kikutani K, shime N, Nishikimi M, Ota K, Hattori M, Ohshimo S., 2nd Joint Congress of JSICM/TSCCM/TSECCM, 2023/10/14, Without Invitation, English, Taiwan
  37. Results of a Questionnaire Survey on the Time Required to Perform Cardiopulmonary Resuscitation on Patients with Cardiopulmonary Arrest., Tanabe Y, Maeda S, Ishikawa E, Shime N., ISQua SEOUL 2023, 2023/08/27, Without Invitation, English, Seoul
  38. Volume-outcome relationship in pediatric sepsis: a retrospective cohort study using a Japanese nationwide inpatient database., Ohki S, Otani M, Tomioka S, Matsuda S, Shime N., ESICM EURO ASIA 2023, 2023/06/09, Without Invitation, English, MUMBAI
  39. Impact of Antimicrobial Use at the Start of Mechanical Ventilation on Ventilator-associated Lower Respiratory Tract Infections in Patients With Acute Respiratory Distress Syndrome Related to Coronavirus Disease 2019., Ishii J, Nishikimi M, Shimatani T, Ota K, Ohshimo S, Shime N., American Thoracic Society 2023 International Conference, 2023/05/17, Without Invitation, English, Washington, DC
  40. Increase in Burden of Patients With Severe COVID-19 Nationwide Was Associated With Higher Mortality Rate of Patients With COVID-19 Requiring Mechanical Ventilation: An Observational Study of a National Database in Japan., Kikutani K, Nishikimi M, Ohshimo S, Shime N, the Japan ECMO network., American Thoracic Society 2023 International Conference, 2023/05/17, Without Invitation, English, Washington, DC
  41. Three Novel Chest CT Subtypes Identified by Latent Class Analysis Among Severe ARDS Patients Requiring ECMO: Potential for Importance of Differential Management During ECMO According to the Subtype., Nishikimi M, Ohshimo S, Fukumoto W, Awai K, Kyo M, Shime N., American Thoracic Society 2023 International Conference, 2023/05/17, Without Invitation, English, Washington, DC
  42. Pneumothorax in patients with ARDS requiring V-V ECMO., Utsumi S, Nishikimi M, Ohshimo S, Shime N., Eur ELSO 2023, 2023/04/26, Without Invitation, English, Lisbon

Awards

  1. Paul dudley whiteinternational scholar award, American heart assocaition, Highest ranked abstract from Japan at at the Resuscitation Science Symposium 2023
  2. 2022/07/03, Joint Congress Award of the 1st Joint Scientific Congress of TSCCM, TSECCM and JSICM Congress, Taiwan Society of Critical Care Medicine. Taiwan Society of Emergency and Critical Care Medicine, Chair of the Excecutive Board of the Japanese Society of Intensive Care Medicine, Prognostic analysis of patients with severe COVID-19 receiving mechanical ventilation with or without ECMO: An interim analysis of Japan national registry
  3. 2021/09/01, World congress of Anaesthesiologists 2021 BEST200, 17th World Congress of Anaesthesiologists, European Accreditation Council for Continuing Medical Educcation, Preventing bronchial intubation in children using a computer-assisted auscultation system

External Funds

Acceptance Results of Competitive Funds

  1. Research Program on Emerging and Re-emerging Infectious Diseases, 2024, 2025
  2. Research Program on Emerging and Re-emerging Infectious Diseases, 2025, 2028
  3. Research Program on Emerging and Re-emerging Infectious Diseases, 2024/04/01, 2025/03/31
  4. Research Program on Emerging and Re-emerging Infectious Diseases, 2022//1/0/, 2023//0/3/
  5. Research Program on Emerging and Re-emerging Infectious Diseases, 2023/04, 2024/03
  6. Research Program on Emerging and Re-emerging Infectious Diseases, 2021/04/23, 2022/03/31
  7. Research Program on Emerging and Re-emerging Infectious Diseases, 2022/04/01, 2023/03/31
  8. 2021, 2022
  9. 2011, 2014
  10. 2012, 2016
  11. 2014, 2014
  12. 2017, 2019
  13. 2017, 2019
  14. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2017, 2019
  15. 2017/.4, 2018/.3
  16. 2017/.6
  17. Development of Medical Devices and Systems for Advanced Medical Services , 2017/08/01, 2018/03/31
  18. Development of Medical Devices and Systems for Advanced Medical Services , 2018/04/01, 2019/03/31
  19. Development of Medical Devices and Systems for Advanced Medical Services, Development of Medical Devices and Systems for Advanced Medical Services, 2019, 2019
  20. 2019, 2020
  21. Acceleration Transformative Research for Medical Innovation, 2019/04/01, 2020/03/31
  22. 2020, 2020
  23. KAKENHI(Grant-in-Aid for Scientific Research (B)), 2020, 2023
  24. Acceleration Transformative Research for Medical Innovation, 2020/04/01, 2021/09/30
  25. 2020, 2021
  26. Development of Medical Devices and Systems for Advanced Medical Services, Development of Medical Devices and Systems for Advanced Medical Services, 2020, 2020

Social Activities

Organizing Academic Conferences, etc.

  1. 2025/01, 2025/01
  2. 2023/03, 2023/03
  3. INTERNATIONAL SERIAL VIRTUAL WEBINAR MANAGEMENT OF COVID-19 PATIENTS IN JAPAN AND VIETNAM, Chair, 2021/11, 2021/11
  4. 2020/12, 2020/12
  5. 2018/12, 2018/12
  6. 2018/05, 2018/05
  7. 2018/10, 2018/10
  8. 2017/06, 2017/06
  9. 2016/06, 2016/06
  10. 2017/05, 2017/05
  11. 2016/09, 2016/09

Other Social Contributions

  1. ECMO simulation labo., ECMO simulation labo., NPO ECMO JAPAN, 2019/08/31, 2019/09/01, Planner, Seminar or workshop, Scientific organization
  2. ECMO simulation labo., ECMO simulation labo., NPO ECMO JAPAN, 2017/05/27, 2017/05/28, Planner, Seminar or workshop, Scientific organization
  3. PALS provider course, PALS provider course, JIPICC, 2019/08/17, 2019/08/18, Planner, Seminar or workshop, Scientific organization

History as Peer Reviews of Academic Papers

  1. 2024, journal of Intensive Care, Chief editor, 38
  2. 2024, BMC pulmonary med, 1
  3. 2024, CHEST, Others, 1
  4. 2024, BMC Pulmonary Medicine, 3
  5. 2024, Current Therapeutic Research, Others, 1
  6. 2024, The Lancet Infectious Diseases, 1
  7. 2024, Acute medicine & surgery, 2
  8. 2024, British J of Anesthesia, 1
  9. 2024, Journal of International Medical Research, 1
  10. 2024, Resp Investigation, Others, 1
  11. 2023, Respiratory Investigation, 1
  12. 2023, J cardiothorac surg, 1
  13. 2022, J of Pediatric Nursing, Others, 1
  14. 2023, BJA, Others, 1
  15. 2022, Internal Medicine, 1
  16. 2022, Medical Communication, Others, 1
  17. 2022, J of Pediatric Intensive Care, Others, 1
  18. 2021, British Journal of Anaesthesia, Others, 1
  19. 2021, Journal of Pediatric Intensive Care, Others, 1
  20. 2021, The Journal of Medical Investigation, Others, 1
  21. 2021, J of Perinatoloigy, Others, 1
  22. 2021, Frontiers in Medicine, Others, 1
  23. 2021, Clinical Infectious Disease, Others, 1
  24. 2021, BMJ case reports, Others, 2
  25. 2021, Japanese Medical Association Journal, Others, 1
  26. 2021, Scandinavian J of Trauma and Resuscitation, Others, 1
  27. 2021, J of Thoracic Disease, Others, 1
  28. 2020, International Journal of Infectious Diseases, 1
  29. 2020, Acute Medicine & Surgery, 4
  30. 2020, BMJ open, 2
  31. 2020, Cardiovascular Diagnosis and Therapy, 1
  32. 2020, Journal of International Medical Research, Others, 1
  33. 2020, Journal of Japanese Association for Acute Medicine, 4
  34. Journal of Japanese Society of Emergency Pediatrics, 2
  35. 2020, J of Artificial Organs, 2
  36. Liver International, 1
  37. 2020, Pediatrics International, 1
  38. 2020, Respiratory Medicine Case Reports, 4
  39. 2020, The Lancet Regional health western pacific, 1
  40. 2020, J Clinical Microbiology, Others, 1
  41. 2020, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2
  42. 2020, J of Infection and Chemotherapy, 6
  43. 2020, Pediatric Critical Care Medicine, Editor, Associate Editor, 14
  44. 2020, J Intensive Care, Editor, 14
  45. 2019, Infect Drug Resist, 3
  46. Pros One, Others, 1
  47. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Others, 1
  48. 2019, Clinical Interventions in Aging, Others, 1
  49. 2019, Pedaitr Crit Care Med, Editor, 11
  50. 2019, J Intensive care, Editor, 5
  51. 2018, J of Artif Organs, Others, 2
  52. 2018, J Antimicrobial Chemother, 1
  53. 2018, Med Sci Monitoring, Others, 1
  54. 2018, Int J Infect Dis, Others, 1
  55. 2018, Clinical epidemiology, Others, 1
  56. 2018, BMC pediatrics, Others, 1
  57. 2018, J Infect Chemother, Others, 4
  58. 2018, Pediatr Crit Care Med, Editor, 11
  59. 2018, J intensive care, Others, Deputy Editor, 15
  60. 2017, Acute Medicine and Surgery, Others, 1
  61. 2017, BMC pediatrics, Others, 1
  62. 2017, European Respiratory Reviews, Others, 1
  63. 2017, BMC Anesthesiology, Others, 1
  64. 2017, J Artif Organs, Others, 1
  65. 2017, Pulsus Journals, Others, 1
  66. 2017, Geriatrics Gentontology, Others, 1
  67. 2017, J Antimicrobial Chemother, Others, 1
  68. 2017, J of Infection and Chemotherapy, Others, 2
  69. 2017, J of Anesthesia, Others, 5
  70. 2017, Pediatr Crit Care Med, Editor, 16
  71. 2017, Pediatrics International, Editor, 9
  72. 2017, Journal of Intensive Care, Editor, 4
  73. 2016, Internal Medicine, Others, 1
  74. 2016, Journal of Cirtical Care, Others, 1
  75. 2016, Hospital practice, Others, 1
  76. 2016, Respiratory Medicine Case Reports, Others, 1
  77. 2016, BMC Anesthesiology, Others, 1
  78. 2016, Journal of Anesthesia, Others, 3
  79. 2016, Pediatrics international, Editor, 10
  80. 2016, Journal of Infection and Chemotherapy, Editor, 2
  81. 2016, Pediatric Critical Care Medicine, Editor, 12
  82. 2016, Journal of Intensive Care, Editor, 6
  83. 2015, Circulation Journal, Others, Reviewer, 1
  84. 2015, Hospital Practice, Others, Reviewer, 1
  85. 2015, Journal of Infection and Chemotherapy, Reviewer, 4
  86. 2015, Journal of Anesthesia, Editor, Reviewer, 4
  87. 2015, Journal of Japanese Society of Intensive Care Medicine, Others, Reviewer, 2
  88. 2015, Journal of Japanese Sciety of Surgical Infection, Editor, Editor, 4
  89. 2015, Journal of Intensive Care, Editor, Reviewer, 17
  90. 2015, Journal of Intensive Care, Editor, Associate Editor, 4
  91. 2015, Pediatrics International, Editor, Editor, 71
  92. 2015, Pediatric Critical Care Medicine, Editor, Associate Editor, 15
  93. 2015, Pediatrics International, Others, Reviewer, 2
  94. 2021, J Intensive Care, Editor, Deputy Editor, 141
  95. 2021, Acute Medicine & Surgery, 2
  96. 2021, J of Anesthesia, Others, 1
  97. 2021, Pediatric Critical Care Medicine, Editor, Associate Editor, 1
  98. 2021, Journal of Infection and Chemotherapy, Editor, 1
  99. 2021, BMC pediatrics, Others, 1
  100. 2021, International Journal of Infectious Diseases, Others, 3
  101. 2021, BMJ open, Others, 1
  102. 2021, Infect Drug Resist, Others, 1
  103. 2021, INTENSIVIST, Editor, 1
  104. 2022, INTENSIVIST, Editor, 2
  105. 2022, British Journal of Anaesthesia, Others, 1
  106. 2022, International Journal of Infectious Diseases, Others, 1
  107. 2022, BMC pediatrics, Others, 1
  108. 2022, Pediatric Critical Care Medicine, Editor, Associate Editor, 6
  109. 2022, J Intensive Care, Editor, Deputy Editor, 222
  110. 2022, Scandinavian J of Trauma and Resuscitation and Emergency Medicine, Others, 1
  111. 2023, J Intensive Care, Chief editor, Deputy Editor, 238