Last Updated :2023/02/02

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medical), Assistant Professor
I investigate the physiological mechanism about neurological disease using the clinical experience.

Basic Information

Major Professional Backgrounds

  • 2005/04/01, 2007/03/31, Hiroshima University Hospital, junior resident
  • 2007/04/01, 2009/03/31, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, senior resident
  • 2009/04/01, 2010/03/31, National Hospital Organization Higashi-Hiroshima Medical Center, staff
  • 2010/04/01, 2014/03/31, Hiroshima University Hospital, Department of Clinical Neuroscience and Therapeutics, medical doctor
  • 2014/04/01, 2020/03/31, Suiseikai Kajikawa Hospital, Department of Neurology, Chief of medical doctor
  • 2020/04/01, 2022/03/31, Hiroshima University Hospital, Department of Clinical Neuroscience and Therapeutics, Assistat Professor

Educational Backgrounds

  • Hiroshima University, School of Medicine , Japan, 1999/04, 2005/03
  • Hiroshima University Graduate School of Biomedical and Health Sciences, Department of Clinical Neuroscience and Therapeutics, Neurology, Japan, 2010/04, 2014/03

Academic Degrees

  • Hiroshima University

In Charge of Primary Major Programs

  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Neurology

Affiliated Academic Societies

  • Japanese Society of Internal Medicine, 2005/04
  • Japanese Society of Neurology, 2007/04
  • The Japan Stroke Society, 2007/04
  • The Japan Academy of Neurosonology, 2007/09
  • The Japanese Society of Neuropathology, 2010/11
  • Japanese Headache Society, 2011/06
  • Japan Society of Dementia Research, 2011/09
  • Japanese Society of Clinical Neurophysiology, 2011/09
  • The Japan Epilepsy Society, 2012/06
  • World Stroke Organization, 2012/09
  • Movement Disorder Society, Japan, 2012/10
  • The Japanese Society of Dysphagia Rehabilitation, 2012/10
  • Japanese Society for Clinical Nutrition and Metabolism, 2013/04
  • The Japan Geriatrics Society, 2013/10
  • The Japanese Society for Neuroimmunology, 2013/12
  • The Japan Neuroscience Society, 2014/04
  • The Society of Swallowing and Dysphagia of Japan, 2014/04
  • The Japanese Society of Neuroradiology, 2016/04
  • The Japan Society of Logopedics and Phoniatrics, 2019/04
  • Japanese Society of Neurological Therapeutics, 2021/05
  • The Japan Society of Human Genetics, 2021/07
  • Jananese Society of Bioinformatics, 2022/10

Educational Activity

Course in Charge

  1. 2022, Undergraduate Education, Intensive, Introduction to clinical clerkship
  2. 2022, Undergraduate Education, Year, Medical Neuroscience III
  3. 2022, Undergraduate Education, Intensive, Practice for medical research
  4. 2022, Undergraduate Education, Intensive, Practice of Medicine I
  5. 2022, Undergraduate Education, First Semester, Internal Medicine I
  6. 2022, Undergraduate Education, 1Term, Dysphagia Rehabilitation
  7. 2022, Undergraduate Education, 1Term, Dysphagia Rehabilitation
  8. 2022, Undergraduate Education, 1Term, Dysphagia Rehabilitation

Research Activities

Academic Papers

  1. Cerebral amyloid angiopathy with a varied hemorrhage pattern on T2*-weighted magnetic resonance image, Internal Medicine, 48(9), 735-736, 2009
  2. ★, Cyclin-dependent kinase 5 immunoreactivity for granulovacuolar degeneration., Neuroreport., 23(15), 867-872, 2012
  3. ★, Molecular markers for granulovacuolar degeneration are present in rimmed vacuoles., PLoS ONE., 8(11), e80995, 2013
  4. Characterization and distribution of adaptor protein containing a PH domain, PTB domain and leucine zipper motif (APPL1) in Alzheimer's disease hippocampus: an immunohistochemical study., Brain Research., 1494, 118-124, 2013
  5. ★, Phosphatidylinositol-4,5-bisphosphate is enriched in granulovacuolar degeneration bodies and neurofibrillary tangles., Neuropathology and Applied Neurobiology., 40(4), 489-501, 2014
  6. Fiber Type-Specific Expression of Low-Density Lipoprotein Receptor-Related Protein 6 in Human Skeletal Muscles., Pathobiology., 81(2), 94-99, 2014
  7. ★, The identification of raft-derived tau-associated vesicles that are incorporated into immature tangles and paired helical filaments., Neuropathology and Applied Neurobiology., 42(7), 639-653, 2016
  8. ★, Tongue thickness evaluation using ultrasonography can predict swallowing function in amyotrophic lateral sclerosis patients., ClinNeurophysiol., 127(2), 1669-1674, 2016
  9. The multidisciplinary swallowing team approach decreases pneumonia onset in acute stroke patients., PLoS ONE., 11(5), e0154608, 2016
  10. ★, Prediction of pneumonia in acute stroke patients using tongue pressure measurements., PLoS ONE., 11(11), e0165837, 2016
  11. Development of a candy-sucking test for evaluating oral function in elderly patients with dementia: A pilot study., Geriatrics Gerontology International., 17(11), 1977-1981, 2017
  12. ★, Maximum tongue pressure is associated with swallowing dysfunction in ALS patients., Dysphagia., 32(4), 542-547, 2017
  13. Blood Pressure Variability in Acute Ischemic Stroke: Influence of Infarct Location in the Insular Cortex., Eur Neurol., 79(1-2), 90-99, 2018
  14. ★, Subarachnoid hemorrhage after transient global amnesia caused by cerebral venous congestion: case report, BMC Neurology., 18(1), 36, 2018
  15. Screening for Fabry Disease in Japanese Patients with Young-Onset Stroke by Measuring a-Galactosidase A and Globotriaosylsphingosine., J Stroke Cerebrovasc Dis., 27(12), 3563-3569, 2018
  16. ★, Utility of Minimum Apparent Diffusion Coefficient Ratios in Alberta Stroke Program Early CT Score Regions for Deciding on Stroke Therapy., J Stroke Cerebrovasc Dis., 28(5), 1371-1380, 2019
  17. Serum IgG titers to periodontal pathogens predict 3-month outcome in ischemic stroke patients., PLoS ONE., 15(8), e0237185, 2020
  18. ★, Prediction of independent gait in acute stroke patients with hemiplegia using the Ability for Basic Movement Scale II score., Eur Neurol., 83(1), 49-55, 2020
  19. Serum immunoglobulin G antibody titer to Fusobacterium nucleatum is associated with unfavorable outcome after stroke, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 200(3), 302-309, 2020
  20. Tongue thickness measured by ultrasonography is associated with tongue pressure in the Japanese elderly, PLOS ONE, 15(8), 20200807
  21. Infant critical head injury could be a remote cause of middle-aged cerebral amyloid angiopathy, INTERDISCIPLINARY NEUROSURGERY-ADVANCED TECHNIQUES AND CASE MANAGEMENT, 22, 202012
  22. Simplified cough test can predict the risk for pneumonia in patients with acute stroke, PLOS ONE, 15(9), 20200929
  23. Association between periodontal disease due to Campylobacter rectus and cerebral microbleeds in acute stroke patients, PLOS ONE, 15(10), 20201008
  24. ★, Serum IgG titers against periodontal pathogens are associated with cerebral hemorrhage growth and 3-month outcome, PLoS ONE., 15(10), e0241205, 2020
  25. Delayed Swallowing Reflex is Overlooked in Swallowing Screening Among Acute Stroke Patients, JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 29(12), 2020
  26. Patient Health Questionnaire-9 predicts the functional outcome of stroke patients in convalescent rehabilitation ward, BRAIN AND BEHAVIOR, 10(12), 202012
  27. Lobar microbleeds are associated with cognitive impairment in patients with lacunar infarction, SCIENTIFIC REPORTS, 10(1), 2020
  28. Low dose contrast-induced encephalopathy during diagnostic cerebral angiography., Internal Medicin, 60(4), 629-633, 2021
  29. ★, Association between stroke lesions and videofluoroscopic findings in acute stroke patients., J Neurol., 268(3), 1025-1035, 2021
  30. Cnm-positive Streptococcus mutans and diffusion-weighted imaging hyperintensities in acute intracerebral hemorrhage, Eur J Neurol., 28(5), 1581-1589, 2021
  31. Utility of Magnetic Resonance Spectroscopy for the Progression of Neurological Symptoms in Lenticulostriate Artery Territory Infarction, J Stroke Cerebrovasc Dis, 30(6), 105747, 2021
  32. Impact of anatomical variations on ultrasonographic reference values of lower extremity peripheral nerves, MUSCLE & NERVE, 63(6), 890-896, 202106
  33. Relationship between tongue pressure and dysphagia diet in patients with acute stroke, PLOS ONE, 16(6), 20210604
  34. External cervical resorption detected via cone-beam computed tomography in a patient with myelin oligodendrocyte glycoprotein antibody-associated disease: A case report, CLINICAL CASE REPORTS, 9(7), 202107
  35. Characteristics and Prognostic Factors of Swallowing Dysfunction in Patients with Lateral Medullary Infarction, JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 30(12), 202112
  36. ★, Association of ankle-brachial index with cognitive decline in patients with lacunar infarction, PLoS ONE, 17(2), e0263525, 20220204
  37. ★, Amyloid beta is internalized via macropinocytosis, an HSPG- and lipid raft-dependent and Rac1-mediated process, Frontiers in Molecular Neuroscience, 202202
  38. Assessment of serum IgG titers to various periodontal pathogens associated with atrial fibrillation in acute stroke patients, J Stroke Cerebrovasc Dis., 31(3), 106301, 202203
  39. ★, Clinical factors predicting voluntary driving cessation among patients with Parkinson's disease, Behavioural Neurology, 202203
  40. Diffusion-Weighted Imaging Hyperintensities in Acute and Subacute-Phase Intracerebral Hemorrhage, J Stroke Cerebrovasc Dis., 31(8), 106549, 20220512
  41. Isolated neurohypophysial sarcoidosis involving cavernous sinus mimicking malignant tumor, NMC Case Report Journal, 31-35, 20221231
  42. Progressive multifocal leukoencephalopathy in relapsed Ph+ acute lymphoblastic leukemia after cord blood transplantation and blinatumomab treatment: A case report and literature review, Acta Haematologica, 2022
  43. Reversible brain atrophy in cryptogenic new-onset refractory status epilepticus: a case report, Internal Medicine, 2022
  44. Nerve ultrasonography for the diagnosis and evaluation of neuralgic amyotrophy: A case report, Internal Medicine, 2022
  45. Association between Carotid Wall Shear Stress-Based Vascular Vector Flow Mapping and Cerebral Small Vessel Disease, J Atheroscler Thromb, 2022
  46. A case of natalizumab-associated progressive multifocal leukoencephalopathy followed by immune reconstitution inflammatory syndrome with difficulty in the timing of immunotherapy, Clinical and Experimental Neuroimmunology, 2022
  47. Are patients with Parkinson's disease at a lower risk of catching the common cold? Propensity score matching, Parkinsonism & Related Disorders, 2022
  48. Immediate seizure worsening and 6-month outcomes following first and second SARSCoV2 mRNA vaccinations: a multicenter study with a nationwide survey, Epilepsy & Behavior, 2022
  49. ★, Peak Expiratory Flow, but not Tongue Pressure, Can Predict Pneumonia Development in Older Adults, European Geriatric Medicine, 2023

Invited Lecture, Oral Presentation, Poster Presentation

  1. Incidence and risk factor of a paradoxical effect of levetiracetam for epileptic seizures, Yoshiko Takebayashi, Shuichiro Neshige, Takeo Shishido, Yuki Hayashi, Akiko Segawa, Masahiro Nakamori, Tomohisa Nezu, Shiro Aoki, Yu Yamazaki, Hiroki Ueno, Tomohiko Ohshita, Koji Iida, Hirofumi Maruyama, 2022/09/20, Without Invitation, English
  2. Seizure outcomes following SARS-CoV2 mRNA vaccination in people with epilepsy: multicenter study and nationwide survey, Megumi Nonaka, Shuichiro Neshige, Haruka Ishibashi, Yoshiko Takebayashi, Shiro Aoki, Masahiro Nakamori, Yu Yamazaki, Takeo Shishido, Dai Agari, Kazuhide Ochi, Koji Iida, Hirofumi Maruyama, 2022/09/20, Without Invitation, English
  3. Clinical factors predicting voluntary driving cessation among patients with Parkinson's disease, Hidetada Yamada, Masahiro Nakamori, Tomohisa Nezu, Teppei Kotozaki, Juri Kitamura, Tomohiko Ohshita, Yoshimasa Sueda, Hirofumi Maruyama, 2022/07/21, Without Invitation, English
  4. Quantitative videofluorographic evaluation of swallowing class 0j and 0t foods of Japanese Dysphagia Diet 2013, Chiho Takeda, Mitsuyoshi Yoshida, Masahiro Nakamori, Mineka Yoshikawa, Jun Kayashita, Kazuhiro Tsuga, The 2nd World Dysphagia Summit, 2021/08/19, Without Invitation, English
  5. Lobar cerebral microbleeds are associated with cognitive impairment in lacunar infarction patients, Masahiro Nakamori, Naohisa Hosomi, Keisuke Tachiyama, Teppei Kamimura, Hayato Matsushima, Yuki Hayashi, Eiji Imamura, Shinichi Wakabayashi, Hirofumi Maruyama, ESO-WSO Conference, 2020/11/07, Without Invitation, English
  6. Utility of MR spectroscopy for progression of neurological symptoms in penetrating artery territory infarction, Yuji Shiga, Tomohisa Nezu, Masahiro Nakamori, Naohisa Hosomi, Yuji Akiyama, Keisuke Tachiyama, Teppei Kamimura, Yuki Hayashi, Hayato Matsushima, Eiji Imamura, Naoto Kinoshita, Shiro Aoki, Hiroki Ueno, Tomohiko Ohshita, Shinichi Wakabayashi, Fumiyuki Yamasaki, Kaoru Kurisu, Kazuo Awai, Hirofumi Maruyama, ESO-WSO Conference, 2020/11/07, Without Invitation, English, Vienna, Austria
  7. Serum IgG titers of periodontal pathogens predict hemorrhage growth and 3-month outcome in patients with cerebral hemorrhage, Masahiro Nakamori, Naohisa Hosomi, Hiromi Nishi, Yuji Shiga, Hayato Matsushima, Shiro Aoki, Tomohisa Nezu, Naoto Kinoshita, Eiji Imamura, Shinichi Wakabayashi, Hirofumi Maruyama, Internal Stroke Conference, 2019/02/06, Without Invitation, English
  8. High baPWV is associated with cognitive decline in lacunar infarction patients, Masahiro Nakamori, Hayato Matsushima, Yuta Maetani, Eiji Imamura, Shinichi Wakabayashi, Yasuyo Mimori, Hirofumi Maruyama, 2018/05/23, Without Invitation, English
  9. Investigation of the relationship between videofluoroscopic examination and tongue pressure using a balloon-type device in acute stroke patients, Masahiro Nakamori, Eiji Imamura, Hayato Matsushima, Yuta Maetani, Satomi Kushitani, Shinichi Wakabayashi, Mineka Yoshikawa, Kazuhiro Tsuga, Toshikazu Nagasaki, Naohisa Hosomi, Hirofumi Maruyama, The 23th World Congress of Neurology, 2017/09/17, Without Invitation, English
  10. Raft derived vesicles are another component of neurofibrillary tangle, Masahiro Nakamori, Tetsuya Takahashi, Tomokazu Nishikawa, Tomoyasu Matsubara, Chengyu Li, Yukari Shinozaki, Yoshito Nagano, Hirofumi Maruyama, Masayasu Matsumoto, 2014/09/11, Without Invitation, English
  11. Immunoreactivity for Cyclin-dependent kinase 5 in Granulovacuolar degeneration, Masahiro Nakamori, Tetsuya Takahashi, Yu Yamazaki, Takashi Kurashige, Yoshito Nagano, Takemori Yamawaki, Masayasu Matsumoto, The 13th Asian Oceanian Congress of Neurology, 2012/06/04, Without Invitation, English


  1. 2021/11/06, Phoenix Outstanding Researcher Award, Hiroshima University
  2. 2012/06, Young Investigator Encouragement Grant, The 13th Asian Oceanic Congress of Neurology

External Funds

Acceptance Results of Competitive Funds

  1. 2022, 2024
  2. 2022/12, 2023/11
  3. 2022/11, 2023/10
  4. 2022/08, 2023/07
  5. 2021/12, 2023/11
  6. 2021/04
  7. 2021/04
  8. 2021/04, 2024/03

Social Activities

History as Peer Reviews of Academic Papers

  1. 2020, Brain and Behavior, Others
  2. 2020, Dysphagia, Others
  3. 2020, Gerontology, Others
  4. 2020, Brain and Behavior, Others
  5. 2020, Journal of Pediatric Genetics, Others
  6. 2018, BMJ Open, Others
  7. 2018, Geriatrics and Gerontology International, Others