Fumihiro Morishita
Last Updated :2024/10/01
- Affiliations, Positions
- Graduate School of Integrated Sciences for Life, Assistant Professor
- E-mail
- fumi425hiroshima-u.ac.jp
Basic Information
Educational Backgrounds
- Hiroshima University, Graduate School, Division of Natural Science, Japan, 1985/04, 1988/07
- Hiroshima University, Faculty of Science, Japan, 1979/04, 1983/03
Academic Degrees
- Doctor of Science, Hiroshima University
- Master of Science, Hiroshima University
Research Fields
- Biology;Basic biology;Animal physiology / Animal behavior
Research Keywords
- post-translational modification
- Immunohistochemistry|in situ hybridization
- signal transduction|D-amino acid
- molecular biology|neuropeptides
- RT-PCR|antagonist
- bioactive peptides|neuropeptide
- Physiological function|peptide
- peptide synthesis|D-amino acid
- structure|gene expression
- hormone
Educational Activity
Course in Charge
- 2024, Liberal Arts Education Program1, 2Term, Introductory Seminar for First-Year Students
- 2024, Undergraduate Education, 1Term, Seminar on Biological Science
- 2024, Undergraduate Education, 2Term, Basic Biological Science B
- 2024, Undergraduate Education, 4Term, Animal Physiology A
- 2024, Undergraduate Education, 2Term, Animal Physiology B
- 2024, Undergraduate Education, Second Semester, Seminar for Molecular Physiology
- 2024, Undergraduate Education, Second Semester, Practice for Fundamental Biology II
- 2024, Undergraduate Education, Second Semester, Practice for Fundamental Biology IV
- 2024, Undergraduate Education, 3Term, Laboratory Work in Biology A
- 2024, Graduate Education (Master's Program) , 1Term, Seminar for Advanced Research in Basic Biology A
- 2024, Graduate Education (Master's Program) , 3Term, Seminar for Advanced Research in Basic Biology B
- 2024, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Basic Biology
- 2024, Graduate Education (Master's Program) , 1Term, Seminar for Advanced Research in Basic Biology C
- 2024, Graduate Education (Master's Program) , 3Term, Seminar for Advanced Research in Basic Biology D
- 2024, Graduate Education (Master's Program) , First Semester, Exercises in Basic Biology A
- 2024, Graduate Education (Master's Program) , Second Semester, Exercises in Basic Biology B
- 2024, Graduate Education (Doctoral Program) , 2Term, Seminar for Advanced Research in Basic Biology E
- 2024, Graduate Education (Doctoral Program) , 3Term, Seminar for Advanced Research in Basic Biology F
- 2024, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biomedial Science
- 2024, Graduate Education (Master's Program) , First Semester, Exercises in Biomedical Science A
- 2024, Graduate Education (Master's Program) , Second Semester, Exercises in Biomedical Science B
Research Activities
Academic Papers
- Long-term Xenopus laevis tadpole -heart-organ-culture: Physiological changes in cholinergic and adrenergic sensitivities of tadpole heart with thyroxine-treatment, Current Research in Physiology, 6, 100100, 20230607
- Concomitant downregulation of neuropeptide genes in a marine snail with consecutive sexual maturation after a nuclear disaster in Japan, FRONTIERS IN ENDOCRINOLOGY, 14, 20230310
- Subtypes of beta adrenergic receptors mediating pigment dispersion in chromatophores of the medaka, Oryzias latipes, Comp. Biochem. Physiol., 81C(2), 279-285, 1985
- Responses of the melanophores of the medaka, Oryzias latipes, to adrenergic drugs - Evidence for involvement of alpha 2 adrenergic receptors mediating melanin aggregation, Comp. Biochem. Physiol., 88C(1), 69-74, 1987
- Subtype of alpha adrenoceptors mediating leucosome aggregation in medaka leucophores, J. Sci. Hiroshima Univ., 33(Ser. B, Division 1), 99-112, 1989
- Coexistence of beta 1- and beta 2-adrenoceptors in the melanophore of the goby Tridentiger obscurus, Pigment Cell Res., 3(4), 192-199, 1990
- Alpha-2 adrenoceptor mediates pigment aggregation within melanophores fo the goby, Tridentiger obscurus., J. Sci. Hiroshima Univ., 34, 29-39, 1990
- The background adaptation of the flatfish, Paralichithys olivaceus., Physiol. Behavior, 50, 185-188, 1991
- Measurement of background-visual field in flatfishes by CRT display method., Marine Behavior Physiol., 19, 285-290, 1992
- Two S-Iamide poptides, AKSGFVRIamide and VSSFVRIamide, isolated from an annelide, Perinereis vancaurica., Biol. Bulletin, 184, 216-222, 1993
- Possible involvement of pertussis toxin-sensitive GTP-biniding protein in the alpha2-adrenoceptor-mediated melanosome-aggregation reoponse of goldfish melanophores, J. Exp. Zool., 266, 173-180, 1993
- Inhibition of adenylate cyclase activity in the goldfish melanophores is mediated by a2-adrenoceptors and a pertussis toxin-sensitive GTP-binding protein., J. Comp. Physiol. , 163B, 533-540, 1993
- A myomodulin-CARP-related peptide isolated from a polychaete annelid, Perinereis vancaurica, Zool. Sci., 11(1), 33-38, 1994
- Effects of myomodulin-CARP-family peptides and analogues on the anterior byssus retractor muscle of Mytilus edulis, Peptide Chem., 1994, 289-292, 1995
- Bioactive peptides of annelids are closely related to those of molluscs, Acta Biol. Hungarica, 46(2-4), 453-456, 1995
- The effects of activators of G-proteins, mastoparan and compound 48/80, on the G-protein/adenylate cyclase in cultured melanophores of the black-moor goldfish, Carassius auratus, J.Comp. Physiol., B166, 467-472, 1996
- Subtype of b-adrenoceotprs in the melanophore of Oryzias latipes, Bull. Fac. Life Environ. Sci. Shimane Univ. , 1, 5-7, 1996
- A Novel D-Amino-acid-containing Peptide Isolated from Aplysia Heart, Biochem. Biophys. Res. Commun., 240(2), 354-358, 1997
- Characterization of binding of the annelidan myoactive peptides, GGNG peptides, to tissues of the earthworm, Eisenia foetida, J. Exp. Zool., 279, 562-570, 1997
- Immunochemical demonstration of Eisenia tetradecapeptide, a bioactive peptide isolated from the gut of the earthworm Eisenia foetida, in tissues of the earthworm, Cell Tissue Res., 288, 567-573, 1997
- Immunohistochemical localization of annetocin, an earthworm oxytocin-related peptide, and identification and ultrastructural characteristics of the annetocin-secretory cells in the oligochaete earthworm Eisenia foetida, Zool. Sci., 15, 381-388, 1998
- Release of proteins and polysaccharides from the albumen gland of the freshwater snail Helisoma duryi: Effect of cAMP and brain extracts, J. Comp. Physiol. , 182, 817-825, 1998
- Phylogenetic aspects of structure and action of neuropeptides, Proc. 7th Alahori Conference, 7, 103-108, 1998
- The Aplysia Mytilus inhibitory peptide-related peptides: Identification, cloning, processing, distribution, and action, J. Neurosci., 19(21), 9618-9634, 1999
- b-adrenergic receptor subtypes in melanophores of the marine gobies Tridentiger trigonocephalus and Chasmichthys gulosus, Pigment Cell Res, 12, 206-217, 1999
- Physiological effect and immunohistochemical distribution of a novel D-amino-acid containing cardioactive peptide isolated from of Aplysia heart, Peptide Sci., 1998, 165-168, 1999
- Localization of leech excitatory peptide, a member of the GGNG peptides, in the central nervous system of a leech (Whitmania pigra) by immunohistochemistry and in situ hybridization, Cell Tissue Res., 297, 155-162, 1999
- Immunohistochemical localization of C-RFamide, FMRF-related peptide, in the brain of the goldfish, Carassius auratus, Zool. Sci., 17, 1067-1074, 2000
- Comparative aspects of invertebrate neuropeptides, Acta Biol. Hungarica, 51, 111-132, 2000
- Carassius RFamide, a novel FMRFa-related peptide, is produced within the retina and involved in retinal information processing in cyprinid fish, Neurosci. Lett., 289, 115-118, 2000
- Annelid bioactive peptides: A comparative view, Trends Comp. Biochem. Physiol., 7, 131-141, 2000
- The Enterins: A Novel Family of Neuropeptides Isolated from the Enteric Nervous System and CNS of Aplysia, J. Neurosci., 21(20), 8247-8261, 2001
- The GGNG-peptide family: annelid myoactive peptides, Perspec. Comp. Endocrinol, 905-909, 2001
- A candidate for fish prolactin-releasing peptide isolated from Japanese crucian carp, Recent Advances in Comparative Endocrinology, 29-38, 2001
- Purification and some properties of alanine racemase from a bivalve mollusc Corbicula japonica, J. Exp. Zool., 289, 1-9, 2001
- NdWFamide: a novel excitatory peptide for the cardiovascular regulation of Aplysia, Peptides, 22, 183-189, 2001
- Enhancement of foot formation in Hydra by a novel epitheliopeptide, Hym-323, Development, 128, 437-446, 2001
- The enterins inhibit the contractile activity of the anterior aorta of Aplysia kurodai, J .Exp. Biol., 205, 3525-3533, 2002
- Structural and functional diversity of the Aplysia Mytilus inhibitory peptide-related peptides, Peptides, 23, 1959-1965, 2002
- Aplysia cardioactive peptide (NdWFamide) enhances the L-type Ca2+ current of Aplysia ventricular myocytes, Peptides, 23, 1991-1998, 2002
- A novel GGNG-related neuropeptide from the polychaete Perinereis vancaurica, Peptides, 23, 1379-1390, 2002
- Distribution and function of an Aplysia cardioexcitatory peptide, NdWFamide, in pulmonate snals, J. Exp. Biol., 24, 1533-1544, 2003
- Deamidase inactivates a D-amino acid-containing Aplysia neuropeptide, Cell and tissue research, 24, 45-51, 2003
- Identification of a vasopression-like immunoreactive substance in hydra, Peptides, 24, 17-26, 2003
- PRQFVamid, a novel pentapeptide identified from the CNS and gut of Aplysia, J. Neurophysiol., 89, 3114-3127, 2003
- Distribution of the Aplysia cardiovascular peptide, NdWFamide, in the central and peripheral neurvous systems of Aplysia, Cell Tissue Res., 312, 95-111, 2003
- Cloning and characterization of a candidate nutritive glycoprotein from the albumen gland of the freshwater snail, Helisoma duryi (Mollusca : Pulmonata), Invertebr. Biol., 123(1), 83-92, 2004
- Peptidergic innervation of the vasoconstrictor muscle of the abdominal aorta in Aplysia kurodai., J. Exp. Biol., 207(Pt 25), 4439-4450, 2004
- Purifications, physiological functions and localizations of neuropeptides in a prosobranch gastropod, Thais clavigera, Peptide Sci., 2005, 43-46, 2006
- Regulatory actions of neuropeptides and peptide hormones on the reproduction of molluscs, Can. J. Zool., 88, 825-845, 2010
- Expression of Asn-d-Trp-Phe-NH2 in the brain of the terrestrial slug Limax valentianus, Comp. Biochem. Physiol., 160B(2-3), 89-93, 2011
- Molecular cloning of two distinct precursor genes of NdWFamide, a D-tryptophan-containing neuropeptide of the sea hare, Aplysia kurodai., Peptides, 38(2), 291-301, 2012
- Molecular cloning of precursors for TEP-1 and TEP-2: The GGNG peptide-related peptides of a prosobranch gastropod, Thais clavigera., Peptides, 68, 72-82, 2015
- Characterization of precursor genes encoding D-tryptophan containing neuropeptide NdWFamide of sea hare Aplysia, Peptide Science, 2013, 439-442, 2014
- Novel excitatory neuropeptides isolated from a prosobranch gastropod, Thais clavigera: The molluscan counterpart of the annelidan GGNG peptides, Peptides, 27, 483-492, 2006
- Identification of neuropeptides in gastropod mollusks. - Classical and brand-new approaches –, IOP Conf. Ser.: Earth Environ. Sci., 456, 012001, 2020
Publications such as books
- 2006, Invertebrate Neuropeptides and Hormones: Basic knowledge and recent advances, Neuropeptides in Aplysia: Key players for the neural regulation of physiological functions and behavior., Transworld Research Network, 2006, Scholarly Book, Joint work, 英語, Fumihiro Morishita, Yasuo Furukawa, 81-7895-224-6, 276, 38
- 2015, Handbook of Hormone, 71 Achatina cardio-excitatory peptide-1,
72 Fulicin,
73 Buccalin,
74 Eisenia inhibitory pentapeptide,
75 GGNG peptide,
81 Egg-laying hormone,
92 Leech osmoregulatory factor, Elsevior, 2015, Scholarly Book, Joint work, English, Minakata, H., Morishita, F.,, 978-0-12-801028-0
- 2016, Physiology of Molluscs. A Collection of Selected Reviews., Physiological Functions of Gastropod Peptides and Neurotransmitters., Apple Academic Press, 2016, 11, Scholarly Book, Joint work, English, Mukai ST, Morishita F, 9781771884082, 379-476
- 2017, Biological Effects by Organotins, Neuropeptides and their physiological functions in Mollusks., Springer Japan, 2017, Scholarly Book, Joint work, English, Morishita, F, 9784431564492, 254, 167-198
Invited Lecture, Oral Presentation, Poster Presentation
- Structures and functions of three peptides identified from a gastropod mollusk, Thais clavigera by the Orbitrap-MS/MS., 2021/06/20, Without Invitation, Japanese
- Structure and function of a D-tryptophan-containing neuropeptide in the gastropod mollusks., Fumihiro Morishita, 2019/09/30, With Invitation, English, Faculty of Science and Technology, Maulana Malik Ibrahim State Islamic University, Malang, Indonesia
- Identification of Neuropeptides in Gastropod Mollusks. - Classical and Brand-new Approaches -, Fumihiro Morishita1,, Toshio Takahashi, Takehiro Watanabe, Takuya Uto, Kazuyoshi Ukena, Megumi Furumitsu, Toshihiro Horiguchi, 10th International Conference fo Green Technology, 2019/10/02, With Invitation, English, Maulana Malik Ibrahim State Islamic University, Malan, Indonesia
- Identification of Neuropeptides in Gastropod Mollusks. - Classical and Brand-new Approaches -, Fumihiro Morishita, 2019/10/01, With Invitation, English, State Health Polytechniue, Malang, Indonesia
- Characterization of NdWFamide - A D-tryptophan-containing neuropeptide in Aplysia -, Fumihiro Morishita, 2019/10/04, With Invitation, English, Faculty of Science and Technology, Maulana Malik Ibrahim State Islamic University, Malang, Indonesia
- Characterization of a novel neuropeptide, APFSVWAamide, idendified from a prosobranch gastropod, Thais clavigera, 2007, Without Invitation, Japanese
- Purifications, Physiological functions and Localizations of Neuropeptides in a Prosobranch Gastropod, Thais clavigera., 2005, Without Invitation, Japanese
- Structure and function of a D-tryptophan-containing neuropeptide in the gastropod mollusk, Aplysia kurodai., Morishita, F., Furukawa, Y., CompBiol2015, 2015/12/11, With Invitation, Japanese, Hiroshima