Last Updated :2023/11/02

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medicine), Professor
I am a physcian majoring in respiratory medicine. I am also making a research on pulmonary fiborisis and thoracic malignancies.

Basic Information

Academic Degrees

  • Doctor of Philosophy in Medical Science, Kyoto University

Educational Activity

  • [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
  • [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Respiratory organ internal medicine

Research Keywords

  • Pulmonary fibrosis
  • Thoracic malignancy

Educational Activity

Course in Charge

  1. 2023, Undergraduate Education, Year, Clinical diagnosis and treatment I
  2. 2023, Undergraduate Education, Intensive, Practice for medical research
  3. 2023, Undergraduate Education, Intensive, Practice of Medicine I
  4. 2023, Undergraduate Education, Intensive, Practice of Medicine II
  5. 2023, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  6. 2023, Graduate Education (Master's Program) , 3Term, Advanced Lecture on Preventive Medicine for Evidence-based Health Guidance B
  7. 2023, Graduate Education (Doctoral Program) , 1Term, Principles of Oncology
  8. 2023, Graduate Education (Doctoral Program) , 1Term, Practice of Oncology
  9. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Molecular and internal Medicine
  10. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Molecular and internal Medicine
  11. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Molecular and internal Medicine
  12. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Molecular and internal Medicine
  13. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Multidisciplinary Tumor Board
  14. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Multidisciplinary Tumor Board

Research Activities

Academic Papers

  1. Serum and bronchoalveolar lavage fluid levels of soluble B7H3 in patients with interstitial lung diseases, RESPIRATORY MEDICINE, 212, 202306
  2. Predictive value of serum high-mobility group box 1 levels for checkpoint inhibitor pneumonitis, RESPIROLOGY, 28(4), 380-388, 202304
  3. Preserved ratio impaired spirometry with or without restrictive spirometric abnormality, SCIENTIFIC REPORTS, 13(1), 20230220
  4. Design and rationale of the Japanese Idiopathic Interstitial Pneumonias (JIPS) Registry, RESPIRATORY INVESTIGATION, 61(1), 95-102, 202301
  5. Association between Plasminogen Activator Inhibitor-1 and Osimertinib Tolerance in EGFR-Mutated Lung Cancer via Epithelial-Mesenchymal Transition, CANCERS, 15(4), 202302
  6. Pre-Existing Interstitial Lung Abnormalities Are Independent Risk Factors for Interstitial Lung Disease during Durvalumab Treatment after Chemoradiotherapy in Patients with Locally Advanced Non-Small-Cell Lung Cancer, CANCERS, 14(24), 202212
  7. Nationwide survey of refractory asthma with bronchiectasis by inflammatory subtypes, RESPIRATORY RESEARCH, 23(1), 20221220
  8. Association of the RAGE/RAGE-ligand axis with interstitial lung disease and its acute exacerbation, RESPIRATORY INVESTIGATION, 60(4), 531-542, 202207
  9. Association Between Patient Preference for Inhaler Medications and Asthma Outcomes, JOURNAL OF ASTHMA AND ALLERGY, 15, 1539-1547, 2022
  10. Dupilumab as an adjunct treatment for a patient with steroid-dependent immunoglobulin G4-related disease complicated by asthma: a case report, JOURNAL OF ASTHMA, 59(12), 2395-2401, 20221110
  11. Identification and characterization of lysophosphatidylcholine 14:0 as a biomarker for drug-induced lung disease, SCIENTIFIC REPORTS, 12(1), 20221117
  12. Prevalence of immune-related adverse events and anti-tumor efficacy following immune checkpoint inhibitor therapy in Japanese patients with various solid tumors, BMC CANCER, 22(1), 20221129
  13. Prediction model for patient prognosis in idiopathic pulmonary fibrosis using hybrid radiomics analysis., Research in Diagnostic and Interventional Imaging, 4, 100017-100017, 202212
  14. Predictive role of circulatory levels of high-mobility group box 1 for radiation pneumonitis in patients with non-small cell lung cancer treated with definitive thoracic radiotherapy, INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 27(11), 1698-1705, 202211
  15. Validity and reliability of the Japanese version of the Dyspnea-12 questionnaire in patients with lung cancer., Journal of Pain and Symptom Management, 64(2), e83-e89, 202208
  16. Pneumonia and Meningoencephalitis Due to Varicella-zoster Virus Reinfection and Epstein-Barr Virus Reactivation in a Patient with Rheumatoid Arthritis, INTERNAL MEDICINE, 61(19), 2961-2965, 2022
  17. Association of DNA methylation with steroidogenic enzymes in Cushing's adenoma, ENDOCRINE-RELATED CANCER, 29(8), 495-502, 202208
  18. Stratifin as a novel diagnostic biomarker in serum for diffuse alveolar damage, NATURE COMMUNICATIONS, 13(1), 20221004
  19. Hochuekkito Combined with Pulmonary Rehabilitation in Apathetic Patients with Chronic Obstructive Pulmonary Disease: A Randomized Controlled Pilot Trial, JOURNAL OF CLINICAL MEDICINE, 11(19), 202210
  20. Secondary pulmonary alveolar proteinosis in a patient with systemic lupus erythematosus., Pulmonology, 27(1), 81-83, 202101
  21. Cryptococcal meningitis in a patient with rheumatoid arthritis treated with abatacept., Journal of Clinical Rheumatology, 27(8S), S701-S702, 20211201
  22. Atezolizumab-induced sclerosing cholangitis in a patient with lung cancer: a case report., Cancer Treatment and Research Communications, 26, 100270-100270, 202106
  23. Characteristic computed tomography features in mesenchymal-epithelial transition exon14 skipping-positive non-small cell lung cancer, BMC PULMONARY MEDICINE, 22(1), 20220630
  24. Role of Soluble Receptor for Advanced Glycation End Products in Postoperative Fibrotic Lung Injury, ANNALS OF THORACIC SURGERY, 113(5), 1617-1623, 202205
  25. Vocal cord dysfunction detected by a three-dimensional image of dynamic change in respiratory resistance in a patient with difficult-to-treat asthma: a case report, JOURNAL OF ASTHMA, 59(6), 1157-1161, 20220603
  26. Switching Treatment from Mepolizumab to Benralizumab for Elderly Patients with Severe Eosinophilic Asthma: A Retrospective Observational Study, INTERNAL MEDICINE, 61(11), 1663-1671, 2022
  27. Primary Pulmonary Mucosa-associated Lymphoid Tissue Lymphoma with the High Expression of IgG4, INTERNAL MEDICINE, 61(7), 1043-1048, 2022
  28. Hypomethylation associated vitamin D receptor expression in ATP1A1 mutant aldosterone-producing adenoma, MOLECULAR AND CELLULAR ENDOCRINOLOGY, 548, 20220515
  29. Tolerability and efficacy of IMpower133 regimen modified for dialysis patients with extensive-stage small cell lung cancer: Two case reports, THORACIC CANCER, 12(21), 2956-2960, 202111
  30. Pulmonary Alveolar Proteinosis with Severe Respiratory Failure Improved by Segmental Lung Lavage with Fiberoptic Bronchoscopy under General Anesthesia, INTERNAL MEDICINE, 61(3), 389-393, 2022
  31. Conversion from Positive to Negative EGFR Mutation due to Clonal Selection during Long-Term Treatment with Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors: A Case Report, CASE REPORTS IN ONCOLOGY, 14(3), 1447-1453, 2021
  32. Pneumatosis Intestinalis following Radiation Esophagitis during Chemoradiotherapy for Lung Cancer: A Case Report, CASE REPORTS IN ONCOLOGY, 14(3), 1454-1459, 2021
  33. Accelerated decline in lung function in adults with a history of remitted childhood asthma, EUROPEAN RESPIRATORY JOURNAL, 59(1), 20220101
  34. First-line osimertinib treatment in a patient with lung adenocarcinoma with coexisting epidermal growth factor receptor G719S and de novo T790M mutations, THORACIC CANCER, 13(5), 771-774, 202203
  35. Inhibition of Plasminogen Activator Inhibitor-1 Attenuates Transforming Growth Factor-beta-Dependent Epithelial Mesenchymal Transition and Differentiation of Fibroblasts to Myofibroblasts, PLOS ONE, 11(2), 20160209
  36. Airway inflammation in Japanese COPD patients compared with smoking and nonsmoking controls, INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 10, 185-192, 2015
  37. Effect of increasing respiratory rate on airway resistance and reactance in COPD patients, RESPIROLOGY, 20(1), 87-94, 201501
  38. Effects of a 6-month nurse-led self-management program on comprehensive pulmonary rehabilitation for patients with COPD receiving home oxygen therapy., Rehabilitation Nursing, 40(1), 40-51, 2015
  39. Evaluation of prognostic significance of granulocyte-related factors in cancer patients undergoing personalized peptide vaccination, HUMAN VACCINES & IMMUNOTHERAPEUTICS, 11(12), 2784-2789, 20151202
  40. Histological Quantification of Gene Silencing by Intratracheal Administration of Dry Powdered Small-Interfering RNA/Chitosan Complexes in the Murine Lung, PHARMACEUTICAL RESEARCH, 32(12), 3877-3885, 201512
  41. Immunological evaluation of peptide vaccination for cancer patients with the HLA-A26 allele, CANCER SCIENCE, 106(10), 1257-1263, 201510
  42. MT95-4, a fully humanized antibody raised against aminopeptidase N, reduces tumor progression in a mouse model, CANCER SCIENCE, 106(7), 921-928, 201507
  43. MUC5B promoter polymorphism in Japanese patients with idiopathic pulmonary fibrosis, RESPIROLOGY, 20(3), 439-444, 201504
  44. Baseline KL-6 predicts increased risk for acute exacerbation of idiopathic pulmonary fibrosis, RESPIRATORY MEDICINE, 108(7), 1031-1039, 201407
  45. Differences in serum SP-D levels between German and Japanese subjects are associated with SFTPD gene polymorphisms, BMC MEDICAL GENETICS, 15, 20140108
  46. Characteristics of inspiratory and expiratory reactance in interstitial lung disease, RESPIRATORY MEDICINE, 107(6), 875-882, 201306
  47. Cross-sectional and prospective study of the association between lung function and prediabetes, BMJ Open, 3(2), 20130320
  48. Reply to letter to the Editor: rs4072037 Polymorphisms and their role in gastrointestinal carcinogenesis, RESPIRATORY MEDICINE, 107(1), 159-159, 2013
  49. SK-216, an inhibitor of plasminogen activator inhibitor-1, limits tumor progression and angiogenesis, Molecular Cancer Therapeutics, 12(11), 2378-2388, 20131101
  50. Cigarette smoking decreases dynamic inspiratory capacity during maximal exercise in patients with type 2 diabetes., Hiroshima J Med Sci, 20120601
  51. Different MUC1 gene polymorphisms in German and Japanese ethnicities affect serum KL-6 levels, RESPIRATORY MEDICINE, 106(12), 1756-1764, 201212
  52. Interferon(alpha, beta and omega) receptor2 is a prognostic biomarker for lung cancer., Pathobiology, 20120101
  53. Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected nonsmall cell lung cancer, INTERNATIONAL JOURNAL OF CANCER, 130(2), 377-387, 20120115
  54. PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury, JOURNAL OF PATHOLOGY, 228(2), 170-180, 201210
  55. Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases, Respiratory Investigation, 50(1), 3-13, 20120301
  56. A pilot study of the multiherb Kampo medicine bakumondoto for cough in patients with chronic obstructive pulmonary disease., Phytomedicine, 18(8-9), 625-629, 20110601
  57. Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesothelioma, Oncology Reports, 24(2), 423-431, 20100101
  58. Association of airway inflammation with asthma control level evaluated by the asthma control test, J Asthma, 48(9), 907-913, 20110901
  59. Change in serum KL-6 level from baseline is useful for predicting life-threatening EGFR-TKIs induced interstitial lung disease, Respir Res, 12, 97-107, 20110701
  60. Chronic Hepatitis C Virus Infection is Associated with More Severe Asthma., Allergol Int, 60(3), 299-304, 20110301
  61. Clinical significance of CD151 gene expression in non-small cell lung cancer, Clinical Cancer Research, 7(12), 4109-4114, 20011201
  62. Effect of Mustard Gas Exposure on Incidence of Lung Cancer: A Longitudinal Study, AMERICAN JOURNAL OF EPIDEMIOLOGY, 173(6), 659-666, 2011
  63. Erlotinib efficacy and cerebrospinal fluid concentration in patients with lung adenocarcinoma developing leptomeningeal metastases during gefitinib therapy., Cancer Chemother Pharmacol, 67(6), 1465-9, 20110101
  64. Intra-airway administration of small interfering RNA targeting plasminogen activator inhibitor-1 attenuates allergic asthma in mice., Am J Physiol Lung Cell Mol Physiol, 301(6), L908-916, 20110901
  65. KL-6 concentration in pulmonary epithelial lining fluid is a useful prognostic indicator in patients with acute respiratory distress syndrome, RESPIRATORY RESEARCH, 12, 2011
  66. Levels of surfactant proteins A and D and KL-6 are elevated in the induced sputum of chronic obstructive pulmonary disease patients: A sequential, Respiration, 82(1), 10-18, 20110401
  67. Nicergoline improves Dysphagia by upregulating substance p in the elderly, Medicine (Baltimore), 90(4), 279-283, 20110701
  68. Phase I study docetaxel plus S-1 combination chemotherapy for recurrent non-small cell lung cancer., Oncology Letters, 2, 167-170, 20110101
  69. Regression of a primary pulmonary adenocarcinoma after zoledronic acid monotherapy, Hiroshima Journal of Medical Sciences, 60(1), 7-9, 20110301
  70. Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in ARDS., Chest, 139(2), 296-304, 20100701
  71. Productive cough is an independent risk factor for the development of COPD in former smokers, RESPIROLOGY, 15(2), 313-318, 201002
  72. Suppression of plasminogen activatior inhibitor-1 by RNA interference attenuates pulmonary fibrosis., Thorax, 65(4), 334-340, 20100401
  73. The influence of lung function on exercise capacity in patients with type 2 diabetes, Hiroshima Journal of Medical Sciences, 59(1), 7-13, 20100301
  74. Airflow limitation in smokers is associated with subclinical atherosclerosis, American Journal of Respiratory and Critical Care Medicine, 179(1), 35-40, 20090101
  75. Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: Role of IL-6, FREE RADICAL BIOLOGY AND MEDICINE, 46(8), 1119-1126, 2009
  76. IL-12p40 is essential for the down-regulation of airway hyperresponsiveness in a mouse model of bronchial asthma with prolonged antigen exposure, Clinical and Experimental Allergy, 39(2), 290-298, 20090201
  77. Lymphocyte transformation test is not helpful for the diagnosis of methotrexate-induced pneumonitis in patients with rheumatoid arthritis., Clin Chim Acta, 407(1-2), 25-29, 20090901
  78. Metastatic breast cancer presenting as air-space consolidation on chest computed tomography., Intern Med, 48(9), 727-731, 20090301
  79. Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice, J Pharmacol Exp Ther, 328(1), 55-61, 20090101
  80. Anti-inflammatory effects and clinical efficacy of theophylline and tulobuterol in mild-to-moderate chronic obstructive pulmonary disease, Pulm Pharmacol Ther, 21(6), 874-878, 20081201
  81. Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome, Journal of Internal Medicine, 263(4), 432-439, 20080401
  82. Suppressor of cytokine signaling1 inhibits pulmonary inflammation and fibrosis, J Allergy Clin Immun, 121(5), 1269-1276, 20080201
  83. Tiotropium bromide is effective for severe asthma with noneosinophilic phenotype, European Respiratory Journal, 31(6), 1379-1380, 20080601
  84. Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors, INTERNATIONAL JOURNAL OF CANCER, 122(11), 2612-2620, 20080601
  85. A case of pulmonary asbestosis presenting with temporal arteritis involving multiple medium-sized vessels., Mod Rheumatol, 18(1), 100-104, 20071201
  86. A causal relationship between overproduction of collagen and the diminished SOCS1 expression in fibroblasts from idiopathic pulmonary fibrosis., Biochemical and Biophysisal Research Communications, 353(4), 1004-10, 20070223
  87. Adenoviral transduction of MRP-1/CD9 and KAI1/CD82 inhibits lymph node metastasis in orthotopic lung cancer model., Cancer Research, 67(4), 1744-1749, 20070215
  88. Circulating KL-6/MUC1 mucin carrying sialyl Lewis(a) oligosaccharide is an independent prognostic factor in patients with lung adenocarcinoma., International journal of cancer, 120(12), 2643-9, 20070615
  89. Differetial expression of the glycosylated forms of MUC1 during lung development, Eur J Histochem, 51(2), 95-102, 20070401
  90. Overproduction of collagen and diminished SOCS1 expression are causally linked in fibroblasts from idiopathic pulmonary fibrosis, Biochemical and Biophysical Research Communications, 353(4), 1004-1010, 20070223
  91. Anti-tumor effect of the anti-KL-6/MUC1 monoclonal antibody through exposure of surface molecules by MUC1 capping, Cancer Science, 97(5), 420-429, 20060501
  92. Clinical significance of aminopeptidase N in non-small cell lung cancer., Clinical Cancer Res., 12(13), 3971-3978, 20060601
  93. Effect of CPAP on brachial-ankle pulse wave velocity in patients with OSAHS: An open-labelled study, Respiratory Medicine, 100(12), 2160-2169, 20061201
  94. KL-6, a human MUC1 mucin, promotes proliferation and survival of lung fibroblasts, Biochemical and Biophysical Research Communications, 338(4), 1845-1852, 20051230
  95. The Plasminogen Activation System Reduces Fibrosis in the Lung by a Hepatocyte Growth Factor-Dependent Mechanism, American Journal of Pathology, 164(3), 1091-1098, 20040301
  96. A plasminogen activator inhibitor-1 promoter polymorphism and idiopathic interstitial pneumonia, Molecular Medicine, 9(1-2), 52-56, 20030101
  97. Clinical significance of transmembrane 4 superfamily in colon cancer, British Journal of Cancer, 89(1), 158-167, 20030707
  98. Reduction in fibrotic tissue formation in mice genetically deficient in plasminogen activator inhibitor-1, American Journal of Pathology, 163(2), 445-452, 20030801
  99. Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in mice, American Journal of Physiology - Lung Cellular and Molecular Physiology, 283(5 27-5), L1023-L1032, 20021101
  100. Clinical significance of aminopeptidase N/CD13 expression in human pancreatic carcinoma, Clinical Cancer Research, 9(4), 1503-1508, 20030401
  101. Clinical significance of aminopeptidase N in non-small cell lung cancer, Clinical Cancer Research, 12(13), 3971-3978, 20060701
  102. Adenoviral transduction of MRP-1/CD9 and KAI1/CD82 inhibits lymph node metastasis in orthotopic lung cancer model, Cancer Research, 67(4), 1744-1749, 20070215
  103. Postoperative gluteal skin damage associated with latent development of gluteal muscle damage, JOURNAL OF DERMATOLOGY, 43(5), 547-552, 201605
  104. Comparative Study of Circulating MMP-7, CCL18, KL-6, SP-A, and SP-D as Disease Markers of Idiopathic Pulmonary Fibrosis, DISEASE MARKERS, 20160317
  105. Long-term pulmonary complications of chemical weapons exposure in former poison gas factory workers, INHALATION TOXICOLOGY, 28(8), 343-348, 201607
  106. Inhibition of PAI-1 Limits Tumor Angiogenesis Regardless of Angiogenic Stimuli in Malignant Pleural Mesothelioma, CANCER RESEARCH, 76(11), 3285-3294, 20160601
  107. Sputum Leucine-Rich Alpha-2 Glycoprotein as a Marker of Airway Inflammation in Asthma, PLOS ONE, 11(9), 20160909
  108. Characterization of sputum biomarkers for asthma-COPD overlap syndrome, INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 11, 2457-2465, 20160930
  109. Efficacy and Safety of Long-Term Sirolimus Therapy for Asian Patients with Lymphangioleiomyomatosis, ANNALS OF THE AMERICAN THORACIC SOCIETY, 13(11), 1912-1922, 201611
  110. Clinically remitted childhood asthma is associated with airflow obstruction in middle-aged adults, RESPIROLOGY, 22(1), 86-92, 201701
  111. Carboplatin plus Weekly Paclitaxel Combined with Bevacizumab as First-line Treatment for Non-small Cell Lung Cancer, ANTICANCER RESEARCH, 37(2), 923-928, 201702
  112. Mustard gas exposure and mortality among retired workers at a poisonous gas factory in Japan: a 57-year follow-up cohort study, OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 74(5), 321-327, 201705
  113. Immunological evaluation of peptide vaccination for cancer patients with the HLA-A11(+) or-A33(+) allele, CANCER SCIENCE, 108(4), 598-603, 201704
  114. Suplatast tosilate protects the lung against hyperoxic lung injury by scavenging hydroxyl radicals, FREE RADICAL BIOLOGY AND MEDICINE, 106, 1-9, 201705
  115. AGER gene polymorphisms and soluble receptor for advanced glycation end product in patients with idiopathic pulmonary fibrosis, RESPIROLOGY, 22(5), 965-971, 201707
  116. Westernization of lifestyle affects quantitative and qualitative changes in adiponectin, CARDIOVASCULAR DIABETOLOGY, 16, 20170706
  117. Association between aerobic capacity and the improvement in glycemic control after the exercise training in type 2 diabetes, DIABETOLOGY & METABOLIC SYNDROME, 9, 20170818
  118. Gene expression profiling of idiopathic interstitial pneumonias (IIPs): identification of potential diagnostic markers and therapeutic targets, BMC MEDICAL GENETICS, 18, 20170818
  120. Chronic Intestinal Pseudo-obstruction and Orthostatic Hypotension Associated with Small Cell Lung Cancer that Improved with Tumor Reduction after Chemoradiotherapy, INTERNAL MEDICINE, 56(19), 2627-2631, 2017
  121. Risk factors for stomatitis in patients with lymphangioleiomyomatosis during treatment with sirolimus: A multicenter investigator-initiated prospective study, PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 26(10), 1182-1189, 201710
  122. Feasibility Study of Personalized Peptide Vaccination for Advanced Small Cell Lung Cancer, CLINICAL LUNG CANCER, 18(6), E385-E394, 201711
  123. AGER rs2070600 polymorphism elevates neutrophil-lymphocyte ratio and mortality in metastatic lung adenocarcinoma, ONCOTARGET, 8(55), 94382-94392, 20171107
  124. Calneuron 1 Increased Ca2+ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma, HYPERTENSION, 71(1), 125-133, 201801
  125. Additional Octreotide Therapy to Sirolimus Achieved a Decrease in Sirolimus-refractory Chylous Effusion Complicated with Lymphangioleiomyomatosis, INTERNAL MEDICINE, 56(24), 3327-3331, 2017
  126. Leucine-rich alpha-2 glycoprotein promotes lung fibrosis by modulating TGF-beta signaling in fibroblasts, PHYSIOLOGICAL REPORTS, 5(24), 201712
  127. The extent of ground-glass attenuation is a risk factor of chemotherapy-related exacerbation of interstitial lung disease in patients with non-small cell lung cancer, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 81(1), 131-139, 201801
  128. FAM13A polymorphism as a prognostic factor in patients with idiopathic pulmonary fibrosis, RESPIRATORY MEDICINE, 123, 105-109, 201702
  129. Aberrant G protein-receptor expression is associated with DNA methylation in aldosterone-producing adenoma, MOLECULAR AND CELLULAR ENDOCRINOLOGY, 461(C), 100-104, 2018
  130. A Rare Combination of Dermatomyositis, Interstitial Pneumonia, and Lung Cancer in a Patient Treated with Immunosuppressive Therapy and Chemotherapy, INTERNAL MEDICINE, 57(6), 849-853, 2018
  131. Putative lung adenocarcinoma with epidermal growth factor receptor mutation presenting as carcinoma of unknown primary site A case report, MEDICINE, 97(7), 201802
  132. Purkinje Cell Protein 4 Expression Is Associated With DNA Methylation Status in Aldosterone-Producing Adenoma, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 103(3), 965-971, 201803
  133. Nivolumab-induced severe pancytopenia in a patient with lung adenocarcinoma, LUNG CANCER, 119, 21-24, 201805
  134. Acetylcholine receptor antibody-positive myasthenia gravis associated with small-cell lung cancer: A case report, MEDICINE, 97(17), 201804
  135. Aminopeptidase N/CD13 as a potential therapeutic target in malignant pleural mesothelioma, EUROPEAN RESPIRATORY JOURNAL, 51(5), 20180501
  136. Japanese guideline for the treatment of idiopathic pulmonary fibrosis, RESPIRATORY INVESTIGATION, 56(4), 268-291, 201807
  137. Comparative efficacies of daptomycin, vancomycin, and linezolid in experimental enterococcal peritonitis, JOURNAL OF INFECTION AND CHEMOTHERAPY, 23(7), 498-501, 201707
  138. MUC1 in lung adenocarcinoma: cross-sectional genetic and serological study, BMC CANCER, 17, 263, 20170412
  139. Bevacizumab with Single-agent Chemotherapy in Previously Treated Non-squamous Non-small-cell Lung Cancer: Phase II Study, IN VIVO, 32(5), 1155-1160, 2018
  140. Use of proton pump inhibitors is associated with increased mortality due to nosocomial pneumonia in bedridden patients receiving tube feeding, GERIATRICS & GERONTOLOGY INTERNATIONAL, 18(8), 1215-1218, 201808
  141. Intratracheal Administration of siRNA Dry Powder Targeting Vascular Endothelial Growth Factor Inhibits Lung Tumor Growth in Mice, MOLECULAR THERAPY-NUCLEIC ACIDS, 12, 698-706, 20180907
  142. Influenza infection presenting with pulmonary congestion: influenza myocarditis, RESPIROLOGY CASE REPORTS, 6(7), 201810
  143. Plasminogen activator inhibitor-1 serves an important role in radiation-induced pulmonary fibrosis, EXPERIMENTAL AND THERAPEUTIC MEDICINE, 16(4), 3070-3076, 201810
  144. Alternate-day administration of S-1 for elderly patients with advanced non-small-cell lung carcinoma: A prospective feasibility study, MOLECULAR AND CLINICAL ONCOLOGY, 9(5), 539-544, 201811
  145. Effects of Hochuekkito combined with pulmonary rehabilitation in patients with chronic obstructive pulmonary disease, EXPERIMENTAL AND THERAPEUTIC MEDICINE, 16(6), 5236-5242, 201812
  146. Multicenter phase II study on cisplatin, pemetrexed, and bevacizumab followed by maintenance with pemetrexed and bevacizumab for patients with advanced or recurrent nonsquamous non-small cell lung cancer: MAP study, BMC CANCER, 18, 20181210
  147. Measurement of midnight ACTH levels is useful for the evaluation of midnight cortisol levels, STEROIDS, 140, 179-184, 201812
  148. Angiotensin 1-7 suppresses angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 185, 137-141, 201901
  149. Small-Cell Lung Cancer Comorbid with Pulmonary Mycobacterium avium Infection: A Case Report, CHEMOTHERAPY, 63(5), 257-261, 2018
  150. Serial measurements of KL-6 for monitoring activity and recurrence of interstitial pneumonia with anti-aminoacyl-tRNA synthetase antibody A retrospective cohort study, MEDICINE, 97(49), 201812
  151. Nivolumab therapy for lung cancer with tracheo-parenchymal fistula A case report, MEDICINE, 97(50), 201812
  152. Pericardial Effusion With Tamponade in Lung Cancer Patients During Treatment With Nivolumab: A Report of Two Cases, FRONTIERS IN ONCOLOGY, 9, 20190122
  153. Anti-KL-6/MUC1 monoclonal antibody reverses resistance to trastuzumab-mediated antibody-dependent cell-mediated cytotoxicity by capping MUC1, CANCER LETTERS, 442, 31-39, 2019
  154. High preoperative C-reactive protein level is a risk factor for acute exacerbation of interstitial lung disease after non-pulmonary surgery, MEDICINE, 98(5), 201902
  155. Cerebral embolism during edoxaban administration for venous thromboembolism in a patient with lung adenocarcinoma A case report, MEDICINE, 98(12), 201903
  156. Inhibition of PAI-1 limits chemotherapy resistance in lung cancer through suppressing myofibroblast characteristics of cancer-associated fibroblasts, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 23(4), 2984-2994, 201904
  157. Performance Status Is a Risk Factor for Depression before the Diagnosis of Lung Cancer Patients, INTERNAL MEDICINE, 58(7), 915-920, 2019
  158. Photochemical generation of the 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) radical from caged nitroxides by near-infrared two-photon irradiation and its cytocidal effect on lung cancer cells, BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 15, 863-873, 20190410
  159. Suplatast tosilate reduces radiation-induced lung injury in mice through suppression of oxidative stress, FREE RADICAL BIOLOGY AND MEDICINE, 136, 52-59, 20190520
  160. Osimertinib in Elderly Patients with Epidermal Growth Factor Receptor T790M-Positive Non-Small-Cell Lung Cancer Who Progressed During Prior Treatment: A Phase II Trial, ONCOLOGIST, 24(5), 593-+, 201905
  161. Comparison of anti-aminoacyl-tRNA synthetase antibody-related and idiopathic non-specific interstitial pneumonia, RESPIRATORY MEDICINE, 152, 44-50, 201906
  162. A Prospective Cohort Study to Define the Clinical Features and Outcome of Lung Cancers Harboring HER2 Aberration in Japan (HER2-CS STUDY), CHEST, 156(2), 357-366, 201908
  163. Vertebral Osteomyelitis that Developed During Chemotherapy for Lung Cancer, UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, 28(3), 199-200, 2018
  164. Small Cell Lung Cancer with Bizarre Radiographic Findings, INTERNAL MEDICINE, 57(23), 3493-3494, 2018
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Publications such as books

  1. 2020, Acute Respiratory Distress Syndrome, Serum markers of ARDS: How can we know the severity and prognosis from the serum markers?, Springer Nature, 2020, Scholarly Book, Joint work
  2. 2018/01/15, Drug-Induced Ling Injury., Blood tests for the diagnosis and/or management of DLI: what are the clinical significances of KL-6, SP-A, SP-D and DLST in DLI., Springer, 2018, Scholarly Book, Joint work