NOBORU HATTORI
Last Updated :2023/11/02
- Affiliations, Positions
- Graduate School of Biomedical and Health Sciences(Medicine), Professor
- E-mail
- nhattori
hiroshima-u.ac.jp
- Self-introduction
- I am a physcian majoring in respiratory medicine. I am also making a research on pulmonary fiborisis and thoracic malignancies.
Basic Information
Academic Degrees
- Doctor of Philosophy in Medical Science, Kyoto University
Educational Activity
- [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
- [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
- [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine
Research Fields
- Medicine,dentistry, and pharmacy;Clinical internal medicine;Respiratory organ internal medicine
Research Keywords
- Pulmonary fibrosis
- Thoracic malignancy
Educational Activity
Course in Charge
- 2023, Undergraduate Education, Year, Clinical diagnosis and treatment I
- 2023, Undergraduate Education, Intensive, Practice for medical research
- 2023, Undergraduate Education, Intensive, Practice of Medicine I
- 2023, Undergraduate Education, Intensive, Practice of Medicine II
- 2023, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
- 2023, Graduate Education (Master's Program) , 3Term, Advanced Lecture on Preventive Medicine for Evidence-based Health Guidance B
- 2023, Graduate Education (Doctoral Program) , 1Term, Principles of Oncology
- 2023, Graduate Education (Doctoral Program) , 1Term, Practice of Oncology
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Molecular and internal Medicine
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Molecular and internal Medicine
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Molecular and internal Medicine
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Molecular and internal Medicine
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Multidisciplinary Tumor Board
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Multidisciplinary Tumor Board
Research Activities
Academic Papers
- Serum and bronchoalveolar lavage fluid levels of soluble B7H3 in patients with interstitial lung diseases, RESPIRATORY MEDICINE, 212, 202306
- Predictive value of serum high-mobility group box 1 levels for checkpoint inhibitor pneumonitis, RESPIROLOGY, 28(4), 380-388, 202304
- Preserved ratio impaired spirometry with or without restrictive spirometric abnormality, SCIENTIFIC REPORTS, 13(1), 20230220
- Design and rationale of the Japanese Idiopathic Interstitial Pneumonias (JIPS) Registry, RESPIRATORY INVESTIGATION, 61(1), 95-102, 202301
- Association between Plasminogen Activator Inhibitor-1 and Osimertinib Tolerance in EGFR-Mutated Lung Cancer via Epithelial-Mesenchymal Transition, CANCERS, 15(4), 202302
- Pre-Existing Interstitial Lung Abnormalities Are Independent Risk Factors for Interstitial Lung Disease during Durvalumab Treatment after Chemoradiotherapy in Patients with Locally Advanced Non-Small-Cell Lung Cancer, CANCERS, 14(24), 202212
- Nationwide survey of refractory asthma with bronchiectasis by inflammatory subtypes, RESPIRATORY RESEARCH, 23(1), 20221220
- Association of the RAGE/RAGE-ligand axis with interstitial lung disease and its acute exacerbation, RESPIRATORY INVESTIGATION, 60(4), 531-542, 202207
- Association Between Patient Preference for Inhaler Medications and Asthma Outcomes, JOURNAL OF ASTHMA AND ALLERGY, 15, 1539-1547, 2022
- Dupilumab as an adjunct treatment for a patient with steroid-dependent immunoglobulin G4-related disease complicated by asthma: a case report, JOURNAL OF ASTHMA, 59(12), 2395-2401, 20221110
- Identification and characterization of lysophosphatidylcholine 14:0 as a biomarker for drug-induced lung disease, SCIENTIFIC REPORTS, 12(1), 20221117
- Prevalence of immune-related adverse events and anti-tumor efficacy following immune checkpoint inhibitor therapy in Japanese patients with various solid tumors, BMC CANCER, 22(1), 20221129
- Prediction model for patient prognosis in idiopathic pulmonary fibrosis using hybrid radiomics analysis., Research in Diagnostic and Interventional Imaging, 4, 100017-100017, 202212
- Predictive role of circulatory levels of high-mobility group box 1 for radiation pneumonitis in patients with non-small cell lung cancer treated with definitive thoracic radiotherapy, INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 27(11), 1698-1705, 202211
- Validity and reliability of the Japanese version of the Dyspnea-12 questionnaire in patients with lung cancer., Journal of Pain and Symptom Management, 64(2), e83-e89, 202208
- Pneumonia and Meningoencephalitis Due to Varicella-zoster Virus Reinfection and Epstein-Barr Virus Reactivation in a Patient with Rheumatoid Arthritis, INTERNAL MEDICINE, 61(19), 2961-2965, 2022
- Association of DNA methylation with steroidogenic enzymes in Cushing's adenoma, ENDOCRINE-RELATED CANCER, 29(8), 495-502, 202208
- Stratifin as a novel diagnostic biomarker in serum for diffuse alveolar damage, NATURE COMMUNICATIONS, 13(1), 20221004
- Hochuekkito Combined with Pulmonary Rehabilitation in Apathetic Patients with Chronic Obstructive Pulmonary Disease: A Randomized Controlled Pilot Trial, JOURNAL OF CLINICAL MEDICINE, 11(19), 202210
- Secondary pulmonary alveolar proteinosis in a patient with systemic lupus erythematosus., Pulmonology, 27(1), 81-83, 202101
- Cryptococcal meningitis in a patient with rheumatoid arthritis treated with abatacept., Journal of Clinical Rheumatology, 27(8S), S701-S702, 20211201
- Atezolizumab-induced sclerosing cholangitis in a patient with lung cancer: a case report., Cancer Treatment and Research Communications, 26, 100270-100270, 202106
- Characteristic computed tomography features in mesenchymal-epithelial transition exon14 skipping-positive non-small cell lung cancer, BMC PULMONARY MEDICINE, 22(1), 20220630
- Role of Soluble Receptor for Advanced Glycation End Products in Postoperative Fibrotic Lung Injury, ANNALS OF THORACIC SURGERY, 113(5), 1617-1623, 202205
- Vocal cord dysfunction detected by a three-dimensional image of dynamic change in respiratory resistance in a patient with difficult-to-treat asthma: a case report, JOURNAL OF ASTHMA, 59(6), 1157-1161, 20220603
- Switching Treatment from Mepolizumab to Benralizumab for Elderly Patients with Severe Eosinophilic Asthma: A Retrospective Observational Study, INTERNAL MEDICINE, 61(11), 1663-1671, 2022
- Primary Pulmonary Mucosa-associated Lymphoid Tissue Lymphoma with the High Expression of IgG4, INTERNAL MEDICINE, 61(7), 1043-1048, 2022
- Hypomethylation associated vitamin D receptor expression in ATP1A1 mutant aldosterone-producing adenoma, MOLECULAR AND CELLULAR ENDOCRINOLOGY, 548, 20220515
- Tolerability and efficacy of IMpower133 regimen modified for dialysis patients with extensive-stage small cell lung cancer: Two case reports, THORACIC CANCER, 12(21), 2956-2960, 202111
- Pulmonary Alveolar Proteinosis with Severe Respiratory Failure Improved by Segmental Lung Lavage with Fiberoptic Bronchoscopy under General Anesthesia, INTERNAL MEDICINE, 61(3), 389-393, 2022
- Conversion from Positive to Negative EGFR Mutation due to Clonal Selection during Long-Term Treatment with Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors: A Case Report, CASE REPORTS IN ONCOLOGY, 14(3), 1447-1453, 2021
- Pneumatosis Intestinalis following Radiation Esophagitis during Chemoradiotherapy for Lung Cancer: A Case Report, CASE REPORTS IN ONCOLOGY, 14(3), 1454-1459, 2021
- Accelerated decline in lung function in adults with a history of remitted childhood asthma, EUROPEAN RESPIRATORY JOURNAL, 59(1), 20220101
- First-line osimertinib treatment in a patient with lung adenocarcinoma with coexisting epidermal growth factor receptor G719S and de novo T790M mutations, THORACIC CANCER, 13(5), 771-774, 202203
- Inhibition of Plasminogen Activator Inhibitor-1 Attenuates Transforming Growth Factor-beta-Dependent Epithelial Mesenchymal Transition and Differentiation of Fibroblasts to Myofibroblasts, PLOS ONE, 11(2), 20160209
- Airway inflammation in Japanese COPD patients compared with smoking and nonsmoking controls, INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 10, 185-192, 2015
- Effect of increasing respiratory rate on airway resistance and reactance in COPD patients, RESPIROLOGY, 20(1), 87-94, 201501
- Effects of a 6-month nurse-led self-management program on comprehensive pulmonary rehabilitation for patients with COPD receiving home oxygen therapy., Rehabilitation Nursing, 40(1), 40-51, 2015
- Evaluation of prognostic significance of granulocyte-related factors in cancer patients undergoing personalized peptide vaccination, HUMAN VACCINES & IMMUNOTHERAPEUTICS, 11(12), 2784-2789, 20151202
- Histological Quantification of Gene Silencing by Intratracheal Administration of Dry Powdered Small-Interfering RNA/Chitosan Complexes in the Murine Lung, PHARMACEUTICAL RESEARCH, 32(12), 3877-3885, 201512
- Immunological evaluation of peptide vaccination for cancer patients with the HLA-A26 allele, CANCER SCIENCE, 106(10), 1257-1263, 201510
- MT95-4, a fully humanized antibody raised against aminopeptidase N, reduces tumor progression in a mouse model, CANCER SCIENCE, 106(7), 921-928, 201507
- MUC5B promoter polymorphism in Japanese patients with idiopathic pulmonary fibrosis, RESPIROLOGY, 20(3), 439-444, 201504
- Baseline KL-6 predicts increased risk for acute exacerbation of idiopathic pulmonary fibrosis, RESPIRATORY MEDICINE, 108(7), 1031-1039, 201407
- Differences in serum SP-D levels between German and Japanese subjects are associated with SFTPD gene polymorphisms, BMC MEDICAL GENETICS, 15, 20140108
- Characteristics of inspiratory and expiratory reactance in interstitial lung disease, RESPIRATORY MEDICINE, 107(6), 875-882, 201306
- Cross-sectional and prospective study of the association between lung function and prediabetes, BMJ Open, 3(2), 20130320
- Reply to letter to the Editor: rs4072037 Polymorphisms and their role in gastrointestinal carcinogenesis, RESPIRATORY MEDICINE, 107(1), 159-159, 2013
- SK-216, an inhibitor of plasminogen activator inhibitor-1, limits tumor progression and angiogenesis, Molecular Cancer Therapeutics, 12(11), 2378-2388, 20131101
- Cigarette smoking decreases dynamic inspiratory capacity during maximal exercise in patients with type 2 diabetes., Hiroshima J Med Sci, 20120601
- Different MUC1 gene polymorphisms in German and Japanese ethnicities affect serum KL-6 levels, RESPIRATORY MEDICINE, 106(12), 1756-1764, 201212
- Interferon(alpha, beta and omega) receptor2 is a prognostic biomarker for lung cancer., Pathobiology, 20120101
- Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected nonsmall cell lung cancer, INTERNATIONAL JOURNAL OF CANCER, 130(2), 377-387, 20120115
- PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury, JOURNAL OF PATHOLOGY, 228(2), 170-180, 201210
- Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases, Respiratory Investigation, 50(1), 3-13, 20120301
- A pilot study of the multiherb Kampo medicine bakumondoto for cough in patients with chronic obstructive pulmonary disease., Phytomedicine, 18(8-9), 625-629, 20110601
- Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesothelioma, Oncology Reports, 24(2), 423-431, 20100101
- Association of airway inflammation with asthma control level evaluated by the asthma control test, J Asthma, 48(9), 907-913, 20110901
- Change in serum KL-6 level from baseline is useful for predicting life-threatening EGFR-TKIs induced interstitial lung disease, Respir Res, 12, 97-107, 20110701
- Chronic Hepatitis C Virus Infection is Associated with More Severe Asthma., Allergol Int, 60(3), 299-304, 20110301
- Clinical significance of CD151 gene expression in non-small cell lung cancer, Clinical Cancer Research, 7(12), 4109-4114, 20011201
- Effect of Mustard Gas Exposure on Incidence of Lung Cancer: A Longitudinal Study, AMERICAN JOURNAL OF EPIDEMIOLOGY, 173(6), 659-666, 2011
- Erlotinib efficacy and cerebrospinal fluid concentration in patients with lung adenocarcinoma developing leptomeningeal metastases during gefitinib therapy., Cancer Chemother Pharmacol, 67(6), 1465-9, 20110101
- Intra-airway administration of small interfering RNA targeting plasminogen activator inhibitor-1 attenuates allergic asthma in mice., Am J Physiol Lung Cell Mol Physiol, 301(6), L908-916, 20110901
- KL-6 concentration in pulmonary epithelial lining fluid is a useful prognostic indicator in patients with acute respiratory distress syndrome, RESPIRATORY RESEARCH, 12, 2011
- Levels of surfactant proteins A and D and KL-6 are elevated in the induced sputum of chronic obstructive pulmonary disease patients: A sequential, Respiration, 82(1), 10-18, 20110401
- Nicergoline improves Dysphagia by upregulating substance p in the elderly, Medicine (Baltimore), 90(4), 279-283, 20110701
- Phase I study docetaxel plus S-1 combination chemotherapy for recurrent non-small cell lung cancer., Oncology Letters, 2, 167-170, 20110101
- Regression of a primary pulmonary adenocarcinoma after zoledronic acid monotherapy, Hiroshima Journal of Medical Sciences, 60(1), 7-9, 20110301
- Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in ARDS., Chest, 139(2), 296-304, 20100701
- Productive cough is an independent risk factor for the development of COPD in former smokers, RESPIROLOGY, 15(2), 313-318, 201002
- Suppression of plasminogen activatior inhibitor-1 by RNA interference attenuates pulmonary fibrosis., Thorax, 65(4), 334-340, 20100401
- The influence of lung function on exercise capacity in patients with type 2 diabetes, Hiroshima Journal of Medical Sciences, 59(1), 7-13, 20100301
- Airflow limitation in smokers is associated with subclinical atherosclerosis, American Journal of Respiratory and Critical Care Medicine, 179(1), 35-40, 20090101
- Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: Role of IL-6, FREE RADICAL BIOLOGY AND MEDICINE, 46(8), 1119-1126, 2009
- IL-12p40 is essential for the down-regulation of airway hyperresponsiveness in a mouse model of bronchial asthma with prolonged antigen exposure, Clinical and Experimental Allergy, 39(2), 290-298, 20090201
- Lymphocyte transformation test is not helpful for the diagnosis of methotrexate-induced pneumonitis in patients with rheumatoid arthritis., Clin Chim Acta, 407(1-2), 25-29, 20090901
- Metastatic breast cancer presenting as air-space consolidation on chest computed tomography., Intern Med, 48(9), 727-731, 20090301
- Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice, J Pharmacol Exp Ther, 328(1), 55-61, 20090101
- Anti-inflammatory effects and clinical efficacy of theophylline and tulobuterol in mild-to-moderate chronic obstructive pulmonary disease, Pulm Pharmacol Ther, 21(6), 874-878, 20081201
- Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome, Journal of Internal Medicine, 263(4), 432-439, 20080401
- Suppressor of cytokine signaling1 inhibits pulmonary inflammation and fibrosis, J Allergy Clin Immun, 121(5), 1269-1276, 20080201
- Tiotropium bromide is effective for severe asthma with noneosinophilic phenotype, European Respiratory Journal, 31(6), 1379-1380, 20080601
- Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors, INTERNATIONAL JOURNAL OF CANCER, 122(11), 2612-2620, 20080601
- A case of pulmonary asbestosis presenting with temporal arteritis involving multiple medium-sized vessels., Mod Rheumatol, 18(1), 100-104, 20071201
- A causal relationship between overproduction of collagen and the diminished SOCS1 expression in fibroblasts from idiopathic pulmonary fibrosis., Biochemical and Biophysisal Research Communications, 353(4), 1004-10, 20070223
- Adenoviral transduction of MRP-1/CD9 and KAI1/CD82 inhibits lymph node metastasis in orthotopic lung cancer model., Cancer Research, 67(4), 1744-1749, 20070215
- Circulating KL-6/MUC1 mucin carrying sialyl Lewis(a) oligosaccharide is an independent prognostic factor in patients with lung adenocarcinoma., International journal of cancer, 120(12), 2643-9, 20070615
- Differetial expression of the glycosylated forms of MUC1 during lung development, Eur J Histochem, 51(2), 95-102, 20070401
- Overproduction of collagen and diminished SOCS1 expression are causally linked in fibroblasts from idiopathic pulmonary fibrosis, Biochemical and Biophysical Research Communications, 353(4), 1004-1010, 20070223
- Anti-tumor effect of the anti-KL-6/MUC1 monoclonal antibody through exposure of surface molecules by MUC1 capping, Cancer Science, 97(5), 420-429, 20060501
- Clinical significance of aminopeptidase N in non-small cell lung cancer., Clinical Cancer Res., 12(13), 3971-3978, 20060601
- Effect of CPAP on brachial-ankle pulse wave velocity in patients with OSAHS: An open-labelled study, Respiratory Medicine, 100(12), 2160-2169, 20061201
- KL-6, a human MUC1 mucin, promotes proliferation and survival of lung fibroblasts, Biochemical and Biophysical Research Communications, 338(4), 1845-1852, 20051230
- The Plasminogen Activation System Reduces Fibrosis in the Lung by a Hepatocyte Growth Factor-Dependent Mechanism, American Journal of Pathology, 164(3), 1091-1098, 20040301
- A plasminogen activator inhibitor-1 promoter polymorphism and idiopathic interstitial pneumonia, Molecular Medicine, 9(1-2), 52-56, 20030101
- Clinical significance of transmembrane 4 superfamily in colon cancer, British Journal of Cancer, 89(1), 158-167, 20030707
- Reduction in fibrotic tissue formation in mice genetically deficient in plasminogen activator inhibitor-1, American Journal of Pathology, 163(2), 445-452, 20030801
- Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in mice, American Journal of Physiology - Lung Cellular and Molecular Physiology, 283(5 27-5), L1023-L1032, 20021101
- Clinical significance of aminopeptidase N/CD13 expression in human pancreatic carcinoma, Clinical Cancer Research, 9(4), 1503-1508, 20030401
- Clinical significance of aminopeptidase N in non-small cell lung cancer, Clinical Cancer Research, 12(13), 3971-3978, 20060701
- Adenoviral transduction of MRP-1/CD9 and KAI1/CD82 inhibits lymph node metastasis in orthotopic lung cancer model, Cancer Research, 67(4), 1744-1749, 20070215
- Postoperative gluteal skin damage associated with latent development of gluteal muscle damage, JOURNAL OF DERMATOLOGY, 43(5), 547-552, 201605
- Comparative Study of Circulating MMP-7, CCL18, KL-6, SP-A, and SP-D as Disease Markers of Idiopathic Pulmonary Fibrosis, DISEASE MARKERS, 20160317
- Long-term pulmonary complications of chemical weapons exposure in former poison gas factory workers, INHALATION TOXICOLOGY, 28(8), 343-348, 201607
- Inhibition of PAI-1 Limits Tumor Angiogenesis Regardless of Angiogenic Stimuli in Malignant Pleural Mesothelioma, CANCER RESEARCH, 76(11), 3285-3294, 20160601
- Sputum Leucine-Rich Alpha-2 Glycoprotein as a Marker of Airway Inflammation in Asthma, PLOS ONE, 11(9), 20160909
- Characterization of sputum biomarkers for asthma-COPD overlap syndrome, INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 11, 2457-2465, 20160930
- Efficacy and Safety of Long-Term Sirolimus Therapy for Asian Patients with Lymphangioleiomyomatosis, ANNALS OF THE AMERICAN THORACIC SOCIETY, 13(11), 1912-1922, 201611
- Clinically remitted childhood asthma is associated with airflow obstruction in middle-aged adults, RESPIROLOGY, 22(1), 86-92, 201701
- Carboplatin plus Weekly Paclitaxel Combined with Bevacizumab as First-line Treatment for Non-small Cell Lung Cancer, ANTICANCER RESEARCH, 37(2), 923-928, 201702
- Mustard gas exposure and mortality among retired workers at a poisonous gas factory in Japan: a 57-year follow-up cohort study, OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 74(5), 321-327, 201705
- Immunological evaluation of peptide vaccination for cancer patients with the HLA-A11(+) or-A33(+) allele, CANCER SCIENCE, 108(4), 598-603, 201704
- Suplatast tosilate protects the lung against hyperoxic lung injury by scavenging hydroxyl radicals, FREE RADICAL BIOLOGY AND MEDICINE, 106, 1-9, 201705
- AGER gene polymorphisms and soluble receptor for advanced glycation end product in patients with idiopathic pulmonary fibrosis, RESPIROLOGY, 22(5), 965-971, 201707
- Westernization of lifestyle affects quantitative and qualitative changes in adiponectin, CARDIOVASCULAR DIABETOLOGY, 16, 20170706
- Association between aerobic capacity and the improvement in glycemic control after the exercise training in type 2 diabetes, DIABETOLOGY & METABOLIC SYNDROME, 9, 20170818
- Gene expression profiling of idiopathic interstitial pneumonias (IIPs): identification of potential diagnostic markers and therapeutic targets, BMC MEDICAL GENETICS, 18, 20170818
- CLINICAL AND MOLECULAR FEATURES OF RAPIDLY PROGRESSIVE CHRONIC HYPERSENSITIVITY PNEUMONITIS, SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, 34(1), 48-57, 2017
- Chronic Intestinal Pseudo-obstruction and Orthostatic Hypotension Associated with Small Cell Lung Cancer that Improved with Tumor Reduction after Chemoradiotherapy, INTERNAL MEDICINE, 56(19), 2627-2631, 2017
- Risk factors for stomatitis in patients with lymphangioleiomyomatosis during treatment with sirolimus: A multicenter investigator-initiated prospective study, PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 26(10), 1182-1189, 201710
- Feasibility Study of Personalized Peptide Vaccination for Advanced Small Cell Lung Cancer, CLINICAL LUNG CANCER, 18(6), E385-E394, 201711
- AGER rs2070600 polymorphism elevates neutrophil-lymphocyte ratio and mortality in metastatic lung adenocarcinoma, ONCOTARGET, 8(55), 94382-94392, 20171107
- Calneuron 1 Increased Ca2+ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma, HYPERTENSION, 71(1), 125-133, 201801
- Additional Octreotide Therapy to Sirolimus Achieved a Decrease in Sirolimus-refractory Chylous Effusion Complicated with Lymphangioleiomyomatosis, INTERNAL MEDICINE, 56(24), 3327-3331, 2017
- Leucine-rich alpha-2 glycoprotein promotes lung fibrosis by modulating TGF-beta signaling in fibroblasts, PHYSIOLOGICAL REPORTS, 5(24), 201712
- The extent of ground-glass attenuation is a risk factor of chemotherapy-related exacerbation of interstitial lung disease in patients with non-small cell lung cancer, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 81(1), 131-139, 201801
- FAM13A polymorphism as a prognostic factor in patients with idiopathic pulmonary fibrosis, RESPIRATORY MEDICINE, 123, 105-109, 201702
- Aberrant G protein-receptor expression is associated with DNA methylation in aldosterone-producing adenoma, MOLECULAR AND CELLULAR ENDOCRINOLOGY, 461(C), 100-104, 2018
- A Rare Combination of Dermatomyositis, Interstitial Pneumonia, and Lung Cancer in a Patient Treated with Immunosuppressive Therapy and Chemotherapy, INTERNAL MEDICINE, 57(6), 849-853, 2018
- Putative lung adenocarcinoma with epidermal growth factor receptor mutation presenting as carcinoma of unknown primary site A case report, MEDICINE, 97(7), 201802
- Purkinje Cell Protein 4 Expression Is Associated With DNA Methylation Status in Aldosterone-Producing Adenoma, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 103(3), 965-971, 201803
- Nivolumab-induced severe pancytopenia in a patient with lung adenocarcinoma, LUNG CANCER, 119, 21-24, 201805
- Acetylcholine receptor antibody-positive myasthenia gravis associated with small-cell lung cancer: A case report, MEDICINE, 97(17), 201804
- Aminopeptidase N/CD13 as a potential therapeutic target in malignant pleural mesothelioma, EUROPEAN RESPIRATORY JOURNAL, 51(5), 20180501
- Japanese guideline for the treatment of idiopathic pulmonary fibrosis, RESPIRATORY INVESTIGATION, 56(4), 268-291, 201807
- Comparative efficacies of daptomycin, vancomycin, and linezolid in experimental enterococcal peritonitis, JOURNAL OF INFECTION AND CHEMOTHERAPY, 23(7), 498-501, 201707
- MUC1 in lung adenocarcinoma: cross-sectional genetic and serological study, BMC CANCER, 17, 263, 20170412
- Bevacizumab with Single-agent Chemotherapy in Previously Treated Non-squamous Non-small-cell Lung Cancer: Phase II Study, IN VIVO, 32(5), 1155-1160, 2018
- Use of proton pump inhibitors is associated with increased mortality due to nosocomial pneumonia in bedridden patients receiving tube feeding, GERIATRICS & GERONTOLOGY INTERNATIONAL, 18(8), 1215-1218, 201808
- Intratracheal Administration of siRNA Dry Powder Targeting Vascular Endothelial Growth Factor Inhibits Lung Tumor Growth in Mice, MOLECULAR THERAPY-NUCLEIC ACIDS, 12, 698-706, 20180907
- Influenza infection presenting with pulmonary congestion: influenza myocarditis, RESPIROLOGY CASE REPORTS, 6(7), 201810
- Plasminogen activator inhibitor-1 serves an important role in radiation-induced pulmonary fibrosis, EXPERIMENTAL AND THERAPEUTIC MEDICINE, 16(4), 3070-3076, 201810
- Alternate-day administration of S-1 for elderly patients with advanced non-small-cell lung carcinoma: A prospective feasibility study, MOLECULAR AND CLINICAL ONCOLOGY, 9(5), 539-544, 201811
- Effects of Hochuekkito combined with pulmonary rehabilitation in patients with chronic obstructive pulmonary disease, EXPERIMENTAL AND THERAPEUTIC MEDICINE, 16(6), 5236-5242, 201812
- Multicenter phase II study on cisplatin, pemetrexed, and bevacizumab followed by maintenance with pemetrexed and bevacizumab for patients with advanced or recurrent nonsquamous non-small cell lung cancer: MAP study, BMC CANCER, 18, 20181210
- Measurement of midnight ACTH levels is useful for the evaluation of midnight cortisol levels, STEROIDS, 140, 179-184, 201812
- Angiotensin 1-7 suppresses angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 185, 137-141, 201901
- Small-Cell Lung Cancer Comorbid with Pulmonary Mycobacterium avium Infection: A Case Report, CHEMOTHERAPY, 63(5), 257-261, 2018
- Serial measurements of KL-6 for monitoring activity and recurrence of interstitial pneumonia with anti-aminoacyl-tRNA synthetase antibody A retrospective cohort study, MEDICINE, 97(49), 201812
- Nivolumab therapy for lung cancer with tracheo-parenchymal fistula A case report, MEDICINE, 97(50), 201812
- Pericardial Effusion With Tamponade in Lung Cancer Patients During Treatment With Nivolumab: A Report of Two Cases, FRONTIERS IN ONCOLOGY, 9, 20190122
- Anti-KL-6/MUC1 monoclonal antibody reverses resistance to trastuzumab-mediated antibody-dependent cell-mediated cytotoxicity by capping MUC1, CANCER LETTERS, 442, 31-39, 2019
- High preoperative C-reactive protein level is a risk factor for acute exacerbation of interstitial lung disease after non-pulmonary surgery, MEDICINE, 98(5), 201902
- Cerebral embolism during edoxaban administration for venous thromboembolism in a patient with lung adenocarcinoma A case report, MEDICINE, 98(12), 201903
- Inhibition of PAI-1 limits chemotherapy resistance in lung cancer through suppressing myofibroblast characteristics of cancer-associated fibroblasts, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 23(4), 2984-2994, 201904
- Performance Status Is a Risk Factor for Depression before the Diagnosis of Lung Cancer Patients, INTERNAL MEDICINE, 58(7), 915-920, 2019
- Photochemical generation of the 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) radical from caged nitroxides by near-infrared two-photon irradiation and its cytocidal effect on lung cancer cells, BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 15, 863-873, 20190410
- Suplatast tosilate reduces radiation-induced lung injury in mice through suppression of oxidative stress, FREE RADICAL BIOLOGY AND MEDICINE, 136, 52-59, 20190520
- Osimertinib in Elderly Patients with Epidermal Growth Factor Receptor T790M-Positive Non-Small-Cell Lung Cancer Who Progressed During Prior Treatment: A Phase II Trial, ONCOLOGIST, 24(5), 593-+, 201905
- Comparison of anti-aminoacyl-tRNA synthetase antibody-related and idiopathic non-specific interstitial pneumonia, RESPIRATORY MEDICINE, 152, 44-50, 201906
- A Prospective Cohort Study to Define the Clinical Features and Outcome of Lung Cancers Harboring HER2 Aberration in Japan (HER2-CS STUDY), CHEST, 156(2), 357-366, 201908
- Vertebral Osteomyelitis that Developed During Chemotherapy for Lung Cancer, UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, 28(3), 199-200, 2018
- Small Cell Lung Cancer with Bizarre Radiographic Findings, INTERNAL MEDICINE, 57(23), 3493-3494, 2018
- Pre-existing interstitial lung abnormalities are risk factors for immune checkpoint inhibitor-induced interstitial lung disease in non-small cell lung cancer, RESPIRATORY INVESTIGATION, 57(5), 451-459, 201909
- Associations of nutrient intakes with obesity and diabetes mellitus in the longitudinal medical surveys of Japanese Americans, JOURNAL OF DIABETES INVESTIGATION, 10(5), 1229-1236, 201909
- C-C Motif Chemokine Ligand 15 May Be a Useful Biomarker for Predicting the Prognosis of Patients with Chronic Hypersensitivity Pneumonitis, RESPIRATION, 98(3), 212-220, 201909
- Platinum-doublet chemotherapy followed by pembrolizumab therapy for lung cancer with lymphangitis carcinomatosa mimicking interstitial pneumonitis A case report, MEDICINE, 98(33), 201908
- Chemotherapy-associated Acute Exacerbation of Interstitial Lung Disease Shortens Survival Especially in Small Cell Lung Cancer, ANTICANCER RESEARCH, 39(10), 5725-5731, 201910
- Role of B7H3/IL-33 Signaling in Pulmonary Fibrosis-induced Profibrogenic Alterations in Bone Marrow, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 200(8), 1032-1044, 20191015
- Alteration of gut microbiota by a Westernized lifestyle and its correlation with insulin resistance in non-diabetic Japanese men, JOURNAL OF DIABETES INVESTIGATION, 10(6), 1463-1470, 201911
- Non-small Cell Lung Cancer Treated by an Anti-programmed Cell Death-1 Antibody without a Flare-up of Preexisting Granulomatosis with Polyangiitis, INTERNAL MEDICINE, 58(21), 3129-3132, 2019
- Serum Antibody Against NY-ESO-1 and XAGE1 Antigens Potentially Predicts Clinical Responses to Anti-Programmed Cell Death-1 Therapy in NSCLC, JOURNAL OF THORACIC ONCOLOGY, 14(12), 2071-2083, 201912
- Organizing pneumonia in a carrier of human T-cell lymphotropic virus type-1, ANNALS OF THORACIC MEDICINE, 15(1), 41-43, 2020
- Baseline High-Resolution CT Findings Predict Acute Exacerbation of Idiopathic Pulmonary Fibrosis: German and Japanese Cohort Study, JOURNAL OF CLINICAL MEDICINE, 8(12), 201912
- Endoplasmic Reticulum Chaperone Calmegin Is Upregulated in Aldosterone-Producing Adenoma and Associates With Aldosterone Production, HYPERTENSION, 75(2), 492-499, 202002
- Albumin-globulin ratio is a predictive biomarker of antitumor effect of anti-PD-1 antibody in patients with non-small cell lung cancer, INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 25(1), 74-81, 202001
- Prospective, randomized, cross-over pilot study of the effects of Rikkunshito, a Japanese traditional herbal medicine, on anorexia and plasma-acylated ghrelin levels in lung cancer patients undergoing cisplatin-based chemotherapy, INVESTIGATIONAL NEW DRUGS, 38(2), 485-492, 202004
- Treatment rationale and design of the PROLONG study: safety and efficacy of pembrolizumab as first-line therapy for elderly patients with non-small cell lung cancer, JOURNAL OF THORACIC DISEASE, 12(3), 1079-1084, 202003
- Serum high-mobility group box 1 is associated with the onset and severity of acute exacerbation of idiopathic pulmonary fibrosis, RESPIROLOGY, 25(3), 275-280, 202003
- Sputum Vitamin D Binding Protein (VDBP) GC1S/1S Genotype Predicts Airway Obstruction: A Prospective Study in Smokers with COPD, INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 15, 1049-1059, 2020
- Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid is associated with poor prognosis in idiopathic pulmonary fibrosis, RESPIRATORY RESEARCH, 21(1), 20200611
- Final Results from a Phase II Trial of Osimertinib for Elderly Patients with Epidermal Growth Factor Receptor t790m-Positive Non-Small Cell Lung Cancer That Progressed during Previous Treatment, JOURNAL OF CLINICAL MEDICINE, 9(6), 202006
- Acute exacerbation of idiopathic interstitial pneumonias related to chemotherapy for lung cancer: nationwide surveillance in Japan, ERJ OPEN RESEARCH, 6(2), 20200401
- Corticosteroid therapy for organizing pneumonia in a human T-cell lymphotropic virus type-1 carrier, 25, 193-195, 2019
- Secondary pulmonary alveolar proteinosis in acute myeloid leukemia, QJM, 112, 293-294, 2019
- Acquired factor V inhibitor after antibiotic treatment in a patient with pneumonia: A case report, Annals of hematology, 98, 1989-1990, 2019
- Pulmonary cryptococcosis mimicking lung cancer, LANCET INFECTIOUS DISEASES, 19, 1033-1033, 2019
- Deep sulcus sign in pneumothorax, Archivos de Bronconeumologia, 55, 491, 2019
- Acquired T790M-positive squamous cell lung carcinoma that responded to osimertinib, Archivos de Bronconeumologia, 55, 602-603, 2019
- Endobronchial mucosa-associated lymphoid tissue (MALT) lymphoma, QJM, 112, 807-808, 2019
- Primary pulmonary collision tumor comprising squamous cell carcinoma and mucosa-associated lymphoid tissue lymphoma, Lung Cancer, 129, 107-109, 2019
- Pneumatosis cystoides intestinalis in pulmonary mycobacterial disease, British Journal of Hospital Medicine, 80, 2019
- Severe metastatic pulmonary calcification, American Journal of Medicine, 132, e733-e734, 2019
- Multiple patchy pulmonary consolidation in granulomatosis with polyangiitis, RESPIROLOGY CASE REPORTS, 8(7), 202010
- Serum high-mobility group box 1 as a predictive marker for cytotoxic chemotherapy-induced lung injury in patients with lung cancer and interstitial lung disease, RESPIRATORY MEDICINE, 172, 202010
- Extent of pulmonary fibrosis on high-resolution computed tomography is a prognostic factor in patients with pleuroparenchymal fibroelastosis, RESPIRATORY INVESTIGATION, 58(6), 465-472, 202011
- Coexisting TIF1 gamma-positive Primary Pulmonary Lymphoepithelioma-like Carcinoma and Anti-TIF1 gamma Antibody-positive Dermatomyositis, INTERNAL MEDICINE, 59(20), 2553-2558, 2020
- Association of Preexisting Interstitial Lung Abnormalities With Immune Checkpoint Inhibitor-Induced Interstitial Lung Disease Among Patients With Nonlung Cancers, JAMA NETWORK OPEN, 3(11), 20201112
- Clinical significance of BIM deletion polymorphism in chemoradiotherapy for non-small cell lung cancer, CANCER SCIENCE, 112(1), 369-379, 202101
- Correlations of forced oscillometric bronchodilator response with airway inflammation and disease duration in asthma, CLINICAL RESPIRATORY JOURNAL, 15(1), 48-55, 202101
- Two Cases of Cranial Nerve Metastasis Treated with Radiotherapy and Chemotherapy in Patients with Lung Adenocarcinoma, CASE REPORTS IN ONCOLOGY, 13(3), 1495-1500, 2020
- Pirfenidone plus inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomised trial, EUROPEAN RESPIRATORY JOURNAL, 57(1), 20210101
- A case with life-threatening secondary sclerosing cholangitis caused by nivolumab, CLINICAL JOURNAL OF GASTROENTEROLOGY, 14(1), 283-287, 202102
- Alectinib-induced Immune Hemolytic Anemia in a Patient with Lung Adenocarcinoma, INTERNAL MEDICINE, 60(4), 611-615, 2021
- Concomitant emphysema might increase the false-negative rate of urinary antigen tests in patients with pneumococcal pneumonia: results from a retrospective study, EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 40(4), 871-877, 202104
- Autoantibody Positivity Is a Risk Factor for Chemotherapy-induced Exacerbation of Interstitial Pneumonia in Lung Cancer, ANTICANCER RESEARCH, 41(3), 1497-1506, 202103
- Pulmonary lymphangitic carcinomatosis from recurrent gastric cancer 19 years after primary resection: a case report, CLINICAL JOURNAL OF GASTROENTEROLOGY, 14(2), 484-488, 202104
- Pulmonary arteriovenous malformation exhibiting recanalization >10 years after coil embolization Two case reports, MEDICINE, 99(2), 202001
- Prognostic Significance of EGFR Gene Mutation in Patients With EGFR Mutated Non-small Cell Lung Cancer Who Received Best Supportive Care Alone, ANTICANCER RESEARCH, 41(5), 2661-2667, 202105
- Predictive role of circulatory HMGB1 in postoperative acute exacerbation of interstitial lung disease in lung cancer patients, SCIENTIFIC REPORTS, 11(1), 20210512
- Giant Fecaloma Causing Anorexia and Dysuria, CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 18(4), XXX-XXX, 202004
- Lambda Sign: Sarcoidosis, ARCHIVOS DE BRONCONEUMOLOGIA, 56(3), 174-175, 202003
- Endobronchial Diffuse Large B-cell Lymphoma, ARCHIVOS DE BRONCONEUMOLOGIA, 56(4), 251-251, 202004
- Osimertinib for the Treatment of EGFR Mutation-Positive Lung Adenocarcinoma Complicated With Dermatomyositis, ARCHIVOS DE BRONCONEUMOLOGIA, 56(12), 822-823, 202012
- Risk factors associated with increased discontinuation rate of trimethoprim-sulfamethoxazole used as a primary prophylaxis for Pneumocystis pneumonia: A retrospective cohort study, PULMONARY PHARMACOLOGY & THERAPEUTICS, 67, 202104
- D-dimer can be a diagnostic marker for cisplatin-related aortic thrombosis A case report, MEDICINE, 100(7), 20210219
- A machine-learning based approach to quantify fine crackles in the diagnosis of interstitial pneumonia A proof-of-concept study, MEDICINE, 100(7), 20210219
- Efficacy of mepolizumab in elderly patients with severe asthma and overlapping COPD in real-world settings: A retrospective observational study, RESPIRATORY INVESTIGATION, 59(4), 478-486, 202107
- IL-18 binding protein can be a prognostic biomarker for idiopathic pulmonary fibrosis, PLOS ONE, 16(6), 20210604
- Quantitative parameters of lymphocyte nuclear morphology in bronchoalveolar lavage fluid as novel biomarkers for sarcoidosis, ORPHANET JOURNAL OF RARE DISEASES, 16(1), 20210703
- Gemcitabine maintenance therapy after gemcitabine and platinum drug chemotherapy for naive stage IIIB/IV squamous cell lung cancer: a phase II study, ANTI-CANCER DRUGS, 32(7), 767-772, 202108
- Smoldering adult T-cell leukemia complicated with pneumocystis pneumonia: A case report, RESPIRATORY MEDICINE CASE REPORTS, 33, 2021
- Prediction of radiation pneumonitis after definitive radiotherapy for locally advanced non-small cell lung cancer using multi-region radiomics analysis, SCIENTIFIC REPORTS, 11(1), 20210810
- Angiotensin-converting enzyme 2 expression is not induced by renin-angiotensin system in the lung., ERJ OPEN RESEARCH, 20201005
- Durvalumab-induced organizing pneumonia with a diffuse micronodular pattern in a lung cancer patient., AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 201(8), 52-53, 20200415
- Antifibrotic effect of lung-resident progenitor cells with high aldehyde dehydrogenase activity, STEM CELL RESEARCH & THERAPY, 12(1), 20210823
- Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis, STEM CELL RESEARCH & THERAPY, 12(1), 20210916
- Analysis of microRNA Expression in Liquid-Based Cytology Samples May Be Useful for Primary Lung Cancer Diagnosis, AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 156(4), 644-652, 202110
- Association between glucose intolerance and chemotherapy-induced lung injury in patients with lung cancer and interstitial lung disease, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 88(5), 857-865, 202111
- Genotype-specific cortisol production associated with Cushing's syndrome adenoma with PRKACA mutations, MOLECULAR AND CELLULAR ENDOCRINOLOGY, 538, 20211201
- Rapid changes of nailfold capillary abnormalities during treatment for a patient with dermatomyositis complicated by lung cancer: a case report, MODERN RHEUMATOLOGY CASE REPORTS, 5(1), 95-100, 20210102
- ATP1A1 Mutant in Aldosterone-Producing Adenoma Leads to Cell Proliferation, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(20), 202110
- Vertebral osteomyelitis caused by Mycobacteroides abscessus subsp. abscessus resulting in spinal cord injury due to vertebral body fractures, JOURNAL OF INFECTION AND CHEMOTHERAPY, 28(2), 290-294, 202202
- Potential benefits of volumetric modulated arc therapy to reduce the incidence of >= grade 2 radiation pneumonitis in radiotherapy for locally advanced non-small cell lung cancer patients, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 51(12), 1729-1735, 202112
- Pulmonary pleomorphic carcinoma in an elderly patient treated with pembrolizumab shows a marked response, JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 17(6), 1580-1582, 2021
Publications such as books
- 2020, Acute Respiratory Distress Syndrome, Serum markers of ARDS: How can we know the severity and prognosis from the serum markers?, Springer Nature, 2020, Scholarly Book, Joint work
- 2018/01/15, Drug-Induced Ling Injury., Blood tests for the diagnosis and/or management of DLI: what are the clinical significances of KL-6, SP-A, SP-D and DLST in DLI., Springer, 2018, Scholarly Book, Joint work