MEI MATSUZAKI

Last Updated :2026/05/08

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Assistant Professor
E-mail
meimatsuhiroshima-u.ac.jp
Self-introduction
Our research aims to develop genetic modification technology using genome editing in birds, and to apply it to the pharmaceutical and food industries. We will also elucidate the molecular mechanisms of avian reproductive systems and develop reproductive technologies for poultry based on these mechanisms.

Basic Information

Major Professional Backgrounds

  • 2016/04, 2017/03, Gifu University, JSPS Research Fellow (DC)
  • 2017/04, 2018/03, Gifu University, JSPS Research Fellow (PD)
  • 2018/04, 2019/03, Shizuoka University, Science Researcher

Academic Degrees

  • Shizuoka University
  • Gifu University

Research Fields

  • Agricultural sciences;Animal life science;Animal production science

Research Keywords

  • Poultry, Reproduction, Genetic engineering, Genome editing

Affiliated Academic Societies

  • Japanese Society of Animal Science
  • Japan Poultry Science Association
  • Zoological Society of Japan
  • The Japanese Society for Genome Editing

Educational Activity

Course in Charge

  1. 2026, Liberal Arts Education Program1, 1Term, Introduction to Applied Biological Sciences toward SDGs
  2. 2026, Undergraduate Education, 1Term, Introduction to Applied Biological Sciences
  3. 2026, Undergraduate Education, Intensive, Laboratory Work in General Biology I
  4. 2026, Undergraduate Education, 3Term, Bio-organic Chemistry
  5. 2026, Undergraduate Education, Second Semester, Graduation Thesis I
  6. 2026, Undergraduate Education, First Semester, Graduation Thesis II
  7. 2026, Undergraduate Education, Second Semester, Graduation Thesis III
  8. 2026, Undergraduate Education, Intensive, Laboratory Work in Molecular Agro-life ScienceIII
  9. 2026, Undergraduate Education, 4Term, Bio-Analytical Science
  10. 2026, Undergraduate Education, 3Term, Reading of Foreign Literature in Molecular Agro-Life Science
  11. 2026, Undergraduate Education, Intensive, (AIMS)Molecular Agro-life Science
  12. 2026, Undergraduate Education, Intensive, Molecular Agro-life Science
  13. 2026, Graduate Education (Doctoral Program) , 1Term, Research Plans in Life Science
  14. 2026, Graduate Education (Master's Program) , 1Term, Exercises in Food andAgriLife Science A
  15. 2026, Graduate Education (Master's Program) , 2Term, Exercises in Food andAgriLife Science A
  16. 2026, Graduate Education (Master's Program) , 3Term, Exercises in Food andAgriLife Science B
  17. 2026, Graduate Education (Master's Program) , 4Term, Exercises in Food andAgriLife Science B
  18. 2026, Graduate Education (Master's Program) , Year, Research for Academic Degree Dissertation in Food andAgriLife Science
  19. 2026, Graduate Education (Master's Program) , 2Term, Animal Life Science

Research Activities

Academic Papers

  1. ★, Potential of recombinant avian adeno-associated virus as a viral vector for CRISPR/Cas9 delivery to avian cells, Journal of Virological Science, 339, 115263, 202601
    Link to Paper Search Results by DOI
  2. Ovomucoid-null eggs produced via genome-editing technology: Protein composition and physicochemical properties, FOOD BIOSCIENCE, 63, 202501
    Link to Paper Search Results by DOI
  3. An efficient method for raising larvae of sakura shrimp Lucensosergia lucens to the post‑larva stage, Fisheries Science, 90, 581-589, 2024
    Link to Paper Search Results by DOI
  4. Expression of relaxin family peptides receptor 1 and 3 in the ovarian follicle of Japanese quail, Journal of Poultry Science, 61, 2024005, 2024
    Link to Paper Search Results by DOI
  5. Chicken interleukin-5 is expressed in splenic lymphocyte and affects antigen-specific antibody production., Journal oj Poultry Science, 61, 2024002, 2024
    Link to Paper Search Results by DOI
  6. Wnt signaling blockade is essential for maintaining the pluripotency of chicken embryonic stem cells, Poultry Science, 103(2), 103361, 202402
    Link to Paper Search Results by DOI
  7. ★, Sperm replacement in sperm-storage tubules causes last-male sperm precedence in chickens, British Poultry Science, 65(1), 97-104, 2024
    Link to Paper Search Results by DOI
  8. Evaluation of expression systems for recombinant protein production in chicken egg bioreactors, Biotechnology Journal, e2300316, 20231019
    Link to Paper Search Results by DOI
  9. Lipofection with Lipofectamine™ 2000 in a heparin-free growth medium results in high transfection efficiency in chicken primordial germ cells, Biotechnology Journal, 18(12), e2300328, 20231218
    Link to Paper Search Results by DOI
  10. Expression of Relaxin 3 in the Ovarian Follicle of Japanese Quail, JOURNAL OF POULTRY SCIENCE, 60(2), 202310
    Link to Paper Search Results by DOI
  11. Transcription activator-like effector nuclease-mediated deletion safely eliminates the major egg allergen ovomucoid in chickens, FOOD AND CHEMICAL TOXICOLOGY, 175, 202305
    Link to Paper Search Results by DOI
  12. Screening of Optimal CpG-Oligodeoxynucleotide for Anti-Inflammatory Responses in the Avian Macrophage Cell Line HD11, JOURNAL OF POULTRY SCIENCE, 60(1), 202301
    Link to Paper Search Results by DOI
  13. Prediction of sex-determination mechanisms in avian primordial germ cells using RNA-seq analysis, SCIENTIFIC REPORTS, 12(1), 20220817
    Link to Paper Search Results by DOI
  14. Possible involvement of annexin A6 in preferential sperm penetration in the germinal disk region, Reproduction and Fertility, 3(3), 152-161, 2022
    Link to Paper Search Results by DOI
  15. Targeted Knock-in of a Fluorescent Protein Gene into the Chicken Vasa Homologue Locus of Chicken Primordial Germ Cells using CRIS-PITCh Method, JOURNAL OF POULTRY SCIENCE, 59(2), 182-190, 2022
    Link to Paper Search Results by DOI
  16. ★, Sperm Motility Regulation in Male and Female Bird Genital Tracts, Journal of Poultry Science, 59(1), 0200105, 2022
    Link to Paper Search Results by DOI
  17. ★, Longer and faster sperm exhibit better fertilization success in Japanese quail, POULTRY SCIENCE, 100(4), 100980, 2021
    Link to Paper Search Results by DOI
  18. ★, Effect of sperm surface oligosaccharides in sperm passage into sperm storage tubules in Japanese quail (Coturnix japonica), ANIMAL REPRODUCTION SCIENCE, 227, 106731, 2021
    Link to Paper Search Results by DOI
  19. Cyclin D1 gene expression is essential for cell cycle progression from the maternal-to-zygotic transition during blastoderm development in Japanese quail, DEVELOPMENTAL BIOLOGY, 476, 249-258, 2021
    Link to Paper Search Results by DOI
  20. Effect of Anserine and Carnosine on Sperm Motility in the Japanese Quail, JOURNAL OF POULTRY SCIENCE, 58(3), 186-191, 202107
    Link to Paper Search Results by DOI
  21. Knock-in of the duck retinoic acid-inducible gene I (RIG-I) into the Mx gene in DF-1 cells enables both stable and immune response-dependent RIG-I expression, BIOCHEMISTRY AND BIOPHYSICS REPORTS, 27, 101084, 202109
    Link to Paper Search Results by DOI
  22. 5-Aminolevulinic acid improves chicken sperm motility, ANIMAL BIOSCIENCE, 34(12), 1912-1920, 202112
    Link to Paper Search Results by DOI
  23. Expression of Transferrin and Albumin in the Sperm-Storage Tubules of Japanese Quail and their Possible Involvement in Long-Term Sperm Storage, JOURNAL OF POULTRY SCIENCE, 57(1), 88-96, 2020
    Link to Paper Search Results by DOI
  24. Female Japanese quail visually differentiate testosterone-dependent male attractiveness for mating preferences, SCIENTIFIC REPORTS, 8, 2018
    Link to Paper Search Results by DOI
  25. Effects of a Protein Kinase Inhibitor on Sperm Motility in the Japanese Quail, JOURNAL OF POULTRY SCIENCE, 54(1), 73-79, 2017
    Link to Paper Search Results by DOI
  26. Egg Envelope Glycoproteins ZP1 and ZP3 Mediate Sperm-Egg Interaction in the Japanese Quail, JOURNAL OF POULTRY SCIENCE, 54(1), 80-86, 2017
    Link to Paper Search Results by DOI
  27. Expression of Prolactin Receptor on the Surface of Quail Spermatozoa, JOURNAL OF POULTRY SCIENCE, 53(2), 157-164, 2016
    Link to Paper Search Results by DOI
  28. Sperm-Egg Interaction during Fertilization in Birds, JOURNAL OF POULTRY SCIENCE, 53(3), 173-180, 2016
    Link to Paper Search Results by DOI
  29. A unique mechanism of successful fertilization in a domestic bird, SCIENTIFIC REPORTS, 5, 2015
    Link to Paper Search Results by DOI
  30. ★, Lactic acid is a sperm motility inactivation factor in the sperm storage tubules, SCIENTIFIC REPORTS, 5, 2015
    Link to Paper Search Results by DOI
  31. Sperm activation by heat shock protein 70 supports the migration of sperm released from sperm storage tubules in Japanese quail (Coturnix japonica), REPRODUCTION, 147(2), 167-178, 2014
    Link to Paper Search Results by DOI
  32. Sperm Storage in the Female Reproductive Tract in Birds, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 59(4), 334-338, 2013

Publications such as books

  1. 2018/20/18, Reproductive and Developmental Strategies: the Continuity of Life, Postcopulatory reproductive strategies in spermatozoa, Springer, 2018, 2018, Scholarly Book, Joint work, 英語, Matsuzaki, M., Sasanami, T., Iwata, Y., Hirohashi, N., 978-4-431-56609-0
  2. 2017, Avian reproduction: From behavior to molecules, Sperm storage in the female reproductive tract - A conserved reproductive strategy for better fertilization success, Springer, 2017, Scholarly Book, Joint work, 英語, Matsuzaki, M., Sasanami, T., 978-981-10-3975-1
  3. 2017, Avian and reptilian development biology methods and protocols, Handling of gametes for in vitro insemination in birds, Springer, 2017, Scholarly Book, Joint work, 英語, Mizushima, S., Matsuzaki, M., Sasanami, T., 978-1-4939-7216-6
  4. 2014, Sexual Reproduction in Animals and Plants, Specific mechanism of sperm storage in avian oviducts, Springer, 2014, Scholarly Book, Joint work, 英語, Matsuzaki, M., Hiyama, G., Mizushima, S., Shiba, K., Inaba, K., Sasanami, T., 978-4-431-54589-7, 23-29

Awards

  1. 2021/09/16, The Journal of Poultry Science Outstanding Paper Award (2021), Japan Poultry Science Association, Expression of transferrin and albumin in the sperm-storage tubules of Japanese quail and their possible involvement in long-term sperm storage.

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI (Grant-in-Aid for Scientific Research (B)), Receptor-capsid interactions reveal the tropism and availability of avian adeno-associated virus, 2025, 2027
  2. KAKENHI (Grant-in-Aid for Transformative Research Areas), Sperm motility patterns in diorama environment emulating sperm-storage tubules, 2024, 2025
  3. KAKENHI(Grant-in-Aid for Early-Career Scientists), 2020, 2023

Social Activities

History as Committee Members

  1. Editorial Board, 2026/04, Japan Poultry Science Association

Organizing Academic Conferences, etc.

  1. 2021/09, 2021/09