MEI MATSUZAKI

Last Updated :2023/09/05

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Assistant Professor
E-mail
meimatsuhiroshima-u.ac.jp
Self-introduction
Our research aims to develop genetic modification technology using genome editing in birds, and to apply it to the pharmaceutical and food industries. We will also elucidate the molecular mechanisms of avian reproductive systems and develop reproductive technologies for poultry based on these mechanisms.

Basic Information

Major Professional Backgrounds

  • 2016/04, 2017/03, Gifu University, JSPS Research Fellow (DC)
  • 2017/04, 2018/03, Gifu University, JSPS Research Fellow (PD)
  • 2018/04, 2019/03, Shizuoka University, Science Researcher

Academic Degrees

  • Shizuoka University
  • Gifu University

Research Fields

  • Agricultural sciences;Animal life science;Animal production science

Educational Activity

Course in Charge

  1. 2023, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  2. 2023, Undergraduate Education, Intensive, Laboratory Work in General Biology I
  3. 2023, Undergraduate Education, 4Term, Research Front of Food and AgriLife Science
  4. 2023, Undergraduate Education, 3Term, Bio-organic Chemistry
  5. 2023, Undergraduate Education, Second Semester, Graduation Thesis I
  6. 2023, Undergraduate Education, First Semester, Graduation Thesis II
  7. 2023, Undergraduate Education, Second Semester, Graduation Thesis III
  8. 2023, Undergraduate Education, First Semester, Graduation Thesis III
  9. 2023, Undergraduate Education, Intensive, Laboratory Work in Molecular Agro-life ScienceIII
  10. 2023, Undergraduate Education, 4Term, Bio-Analytical Science
  11. 2023, Undergraduate Education, 3Term, Reading of Foreign Literature in Molecular Agro-Life Science
  12. 2023, Graduate Education (Master's Program) , 1Term, Exercises in Food andAgriLife Science A
  13. 2023, Graduate Education (Master's Program) , 2Term, Exercises in Food andAgriLife Science A
  14. 2023, Graduate Education (Master's Program) , 3Term, Exercises in Food andAgriLife Science B
  15. 2023, Graduate Education (Master's Program) , 4Term, Exercises in Food andAgriLife Science B
  16. 2023, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Food andAgriLife Science
  17. 2023, Graduate Education (Master's Program) , 2Term, Animal Life Science

Research Activities

Academic Papers

  1. Transcription activator-like effector nuclease-mediated deletion safely eliminates the major egg allergen ovomucoid in chickens, FOOD AND CHEMICAL TOXICOLOGY, 175, 202305
  2. Screening of Optimal CpG-Oligodeoxynucleotide for Anti-Inflammatory Responses in the Avian Macrophage Cell Line HD11, JOURNAL OF POULTRY SCIENCE, 60(1), 202301
  3. Prediction of sex-determination mechanisms in avian primordial germ cells using RNA-seq analysis, SCIENTIFIC REPORTS, 12(1), 20220817
  4. Possible involvement of annexin A6 in preferential sperm penetration in the germinal disk region, Reproduction and Fertility, 3(3), 152-161, 2022
  5. Targeted Knock-in of a Fluorescent Protein Gene into the Chicken Vasa Homologue Locus of Chicken Primordial Germ Cells using CRIS-PITCh Method, JOURNAL OF POULTRY SCIENCE, 59(2), 182-190, 2022
  6. Longer and faster sperm exhibit better fertilization success in Japanese quail, POULTRY SCIENCE, 100(4), 100980, 2021
  7. ★, Effect of sperm surface oligosaccharides in sperm passage into sperm storage tubules in Japanese quail (Coturnix japonica), ANIMAL REPRODUCTION SCIENCE, 227, 106731, 2021
  8. Cyclin D1 gene expression is essential for cell cycle progression from the maternal-to-zygotic transition during blastoderm development in Japanese quail, DEVELOPMENTAL BIOLOGY, 476, 249-258, 2021
  9. Knock-in of the duck retinoic acid-inducible gene I (RIG-I) into the Mx gene in DF-1 cells enables both stable and immune response-dependent RIG-I expression, Biochemistry and Biophysics Reports, 2021
  10. ★, Sperm Motility Regulation in Male and Female Bird Genital Tracts, Journal of Poultry Science, 59(1), 0200105, 2022
  11. Effect of Anserine and Carnosine on Sperm Motility in the Japanese Quail, JOURNAL OF POULTRY SCIENCE, 58(3), 186-191, 202107
  12. Expression of Transferrin and Albumin in the Sperm-Storage Tubules of Japanese Quail and their Possible Involvement in Long-Term Sperm Storage, JOURNAL OF POULTRY SCIENCE, 57(1), 88-96, 2020
  13. Female Japanese quail visually differentiate testosterone-dependent male attractiveness for mating preferences, SCIENTIFIC REPORTS, 8, 2018
  14. Effects of a Protein Kinase Inhibitor on Sperm Motility in the Japanese Quail, JOURNAL OF POULTRY SCIENCE, 54(1), 73-79, 2017
  15. Egg Envelope Glycoproteins ZP1 and ZP3 Mediate Sperm-Egg Interaction in the Japanese Quail, JOURNAL OF POULTRY SCIENCE, 54(1), 80-86, 2017
  16. Expression of Prolactin Receptor on the Surface of Quail Spermatozoa, JOURNAL OF POULTRY SCIENCE, 53(2), 157-164, 2016
  17. Sperm-Egg Interaction during Fertilization in Birds, JOURNAL OF POULTRY SCIENCE, 53(3), 173-180, 2016
  18. A unique mechanism of successful fertilization in a domestic bird, SCIENTIFIC REPORTS, 5, 2015
  19. ★, Lactic acid is a sperm motility inactivation factor in the sperm storage tubules, SCIENTIFIC REPORTS, 5, 2015
  20. Sperm activation by heat shock protein 70 supports the migration of sperm released from sperm storage tubules in Japanese quail (Coturnix japonica), REPRODUCTION, 147(2), 167-178, 2014
  21. Sperm Storage in the Female Reproductive Tract in Birds, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 59(4), 334-338, 2013
  22. Knock-in of the duck retinoic acid-inducible gene I (RIG-I) into the Mx gene in DF-1 cells enables both stable and immune response-dependent RIG-I expression, BIOCHEMISTRY AND BIOPHYSICS REPORTS, 27, 101084, 202109
  23. 5-Aminolevulinic acid improves chicken sperm motility, ANIMAL BIOSCIENCE, 34(12), 1912-1920, 202112

Publications such as books

  1. 2018/20/18, Reproductive and Developmental Strategies: the Continuity of Life, Postcopulatory reproductive strategies in spermatozoa, Springer, 2018, 2018, Scholarly Book, Joint work, 英語, Matsuzaki, M., Sasanami, T., Iwata, Y., Hirohashi, N., 978-4-431-56609-0
  2. 2017, Avian reproduction: From behavior to molecules, Sperm storage in the female reproductive tract - A conserved reproductive strategy for better fertilization success, Springer, 2017, Scholarly Book, Joint work, 英語, Matsuzaki, M., Sasanami, T., 978-981-10-3975-1
  3. 2017, Avian and reptilian development biology methods and protocols, Handling of gametes for in vitro insemination in birds, Springer, 2017, Scholarly Book, Joint work, 英語, Mizushima, S., Matsuzaki, M., Sasanami, T., 978-1-4939-7216-6
  4. 2014, Sexual Reproduction in Animals and Plants, Specific mechanism of sperm storage in avian oviducts, Springer, 2014, Scholarly Book, Joint work, 英語, Matsuzaki, M., Hiyama, G., Mizushima, S., Shiba, K., Inaba, K., Sasanami, T., 978-4-431-54589-7, 23-29

Invited Lecture, Oral Presentation, Poster Presentation

  1. Last-male sperm precedence during sperm-storage in chicken, Mei Matsuzaki, Tomohiro Sasanami, Poultry Science Association 2023 Annual Meeting, 2023/07/17, Without Invitation, English, Poultry Science Association, Philadelphia, USA
  2. Construction of an Evaluation System for Chicken Egg Bioreactor Using Cultured Chicken Cells, Ryota Kajihara, Kenosuke Ishikawa, Ryo Ezaki, Mei Matsuzaki, Hiroyuki Horiuchi, 2022/11/12, Without Invitation, English, Hiroshima University
  3. Genetic Engineering in Chicken Primordial Germ Cells, Tenkai Watanabe, Kenosuke Ishikawa, Ryo Ezaki, Mei Matsuzaki, Hiroyuki Horiuchi, 2022/11/12, Without Invitation, English, Hiroshima University
  4. Sperm-storage and post-copulatory sexual selection in birds, Matsuzaki, M., Sasanami, T., The 93rd Annual Meeting of the Zoological Society of Japan, 2022/09/08, With Invitation, Japanese, Zoological Society of Japan, Waseda Campus, Waseda University, Tokyo
  5. Candidates for quantitative trait locus involved in sperm midpiece length of Japanese quail, Kobayashi, S., Haqani, M. I., Tsudzuki, M., Dohra, H., Horiuchi, H., Sasanami, T., Matsuzaki, M., The 93rd Annual Meeting of the Zoological Society of Japan, 2022/09/10, Without Invitation, Japanese, Zoological Society of Japan, Waseda Campus, Waseda University, Tokyo

Awards

  1. 2021/09/16, The Journal of Poultry Science Outstanding Paper Award (2021), Japan Poultry Science Association, Expression of transferrin and albumin in the sperm-storage tubules of Japanese quail and their possible involvement in long-term sperm storage.

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Early-Career Scientists), 2020, 2023

Social Activities

Organizing Academic Conferences, etc.

  1. 2021/09, 2021/09