KAZUYA KIKUTANI

Last Updated :2025/12/03

Affiliations, Positions
Graduate School of Biomedical and Health Sciences, Assistant Professor
E-mail
kikutanihiroshima-u.ac.jp

Basic Information

Educational Backgrounds

  • Hiroshima university, Japan, 2007, 2013

Academic Degrees

  • Hiroshima University
  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Emergency medicine

Affiliated Academic Societies

  • Japanese association of acute medicine
  • The japanese society of intensive care medicine
  • Japanese Society of Respiratory Care Medicine
  • The japanese society of internal medicine
  • Japanese Society for Clinical Toxicology

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, Intensive, Introduction to clinical clerkship
  2. 2025, Undergraduate Education, Intensive, Practice of Medicine I

Research Activities

Academic Papers

  1. Association of Medical Burden and Capacity Changes With Clinical Outcomes Among Patients Without COVID-19 During the Pandemic: A Multicenter Retrospective Cohort Study, CRITICAL CARE MEDICINE, 53(10), e1918-e1929, 202510
    Link to Paper Search Results by DOI
  2. Impact of staff turnover on extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients: a nationwide registry-based analysis in Japan, RESUSCITATION PLUS, 26, 202511
    Link to Paper Search Results by DOI
  3. Changes in the neurological status from 30 to 90 days post-cardiac arrest by age: A nationwide retrospective observational study, Resusc Plus, 22, 250228
  4. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024, JOURNAL OF INTENSIVE CARE, 13(1), 20250314
  5. Association between increasing institutional experience with ECPR and outcomes in patients with out-of-hospital cardiac arrest: a nationwide multicenter observational study in Japan (the JAAM-OHCA registry), Resuscitation, 202501
    Link to Paper Search Results by DOI
  6. Resuscitation Attempt and Outcomes in Patients With Asystole Out-of-Hospital Cardiac Arrest, JAMA NETWORK OPEN, 7(11), 20241118
    Link to Paper Search Results by DOI
  7. Hypercalcemic Crisis Complicated With Acute Respiratory Distress Syndrome Due to Hot Spring Drowning: A Case Report, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(4), 20240416
    Link to Paper Search Results by DOI
  8. Diagnostic utility of plasma translocator protein 18 kDa (TSPO) in sepsis: A case-control study, MEDICINE, 103(44), 20241101
    Link to Paper Search Results by DOI
  9. Increased national critical care demands were associated with a higher mortality of intubated COVID-19 patients in Japan: a retrospective observational study, JOURNAL OF INTENSIVE CARE, 12(1), 20241105
    Link to Paper Search Results by DOI
  10. Identifying Subgroups with Differential Responses to Amiodarone among Cardiac Arrest Patients with a Shockable Rhythm at Hospital Arrival using the Machine Learning Approach, REVIEWS IN CARDIOVASCULAR MEDICINE, 25(7), 202407
    Link to Paper Search Results by DOI
  11. External validation of the rCAST for patients after in-hospital cardiac arrest: a multicenter retrospective observational study, SCIENTIFIC REPORTS, 14(1), 20240221
    Link to Paper Search Results by DOI
  12. Fulminant myocarditis proven by early biopsy and outcomes, Eur Heart J, 20231106
  13. Prediction of the neurological outcomes post-cardiac arrest: A prospective validation of the CAST and rCAST, The American Journal of Emergency Medicine, 20231020
  14. Medical equipment that improve safety and outcomes of inter-facility transportation of critically ill patients: A systematic review, Medicine (Baltimore), . 2023 Jun 2;102(22):e33865., 20230602
  15. ★, GENETIC DELETION OF TRANSLOCATOR PROTEIN EXACERBATES POST-SEPSIS SYNDROME WITH ACTIVATION OF THE C1Q PATHWAY IN SEPTIC MOUSE MODEL, SHOCK, 59(1), 82-90, 202301
    Link to Paper Search Results by DOI
  16. Quantification of respiratory sounds by a continuous monitoring system can be used to predict complications after extubation: a pilot study, JOURNAL OF CLINICAL MONITORING AND COMPUTING, 37(1), 237-248, 202302
    Link to Paper Search Results by DOI
  17. Regional respiratory sound abnormalities in pneumothorax and pleural effusion detected via respiratory sound visualization and quantification: case report, JOURNAL OF CLINICAL MONITORING AND COMPUTING, 36(6), 1761-1766, 202212
    Link to Paper Search Results by DOI
  18. Prediction of Prehospital Change of the Cardiac Rhythm From Nonshockable to Shockable in Out-of-Hospital Patients With Cardiac Arrest: A Post Hoc Analysis of a Nationwide, Multicenter, Prospective Registry, JOURNAL OF THE AMERICAN HEART ASSOCIATION, 11(12), 20220621
    Link to Paper Search Results by DOI
  19. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), ACUTE MEDICINE & SURGERY, 8(1), 202101
    Link to Paper Search Results by DOI
  20. A novel system that continuously visualizes and analyzes respiratory sounds to promptly evaluate upper airway abnormalities: a pilot study, JOURNAL OF CLINICAL MONITORING AND COMPUTING, 36(1), 221-226, 202202
    Link to Paper Search Results by DOI
  21. Regional respiratory sound abnormalities in pneumothorax and pleural effusion detected via respiratory sound visualization and quantification: case report, Journal of clinical monitoring and computing, 20220211
  22. Microglial translocator protein and stressor-related disorder, Neurochem Int ., 20200924
  23. Early PaCO2 Changes after Initiating Extracorporeal Membrane Oxygenation: Considerations for Future Research, Am J Respir Crit Care Med ., 1600-1601
  24. Pharmacological and Genetic Inhibition of Translocator Protein 18 kDa Ameliorated Neuroinflammation in Murine Endotoxemia Model, Shock
  25. A Ruptured Mediastinal Bronchial Artery Aneurysm Treated with Urgent Thoracic Endovascular Aortic Repair, Intern Med., 1283-1286
  26. Potential Confounders of Procalcitonin-Guided Antibiotic Therapy for Sepsis, Crit Care Med ., e1310-e1311, 2017
  27. Potential confounders affecting the reintubation rate : Discussion on "Reconnection to mechanical ventilation for 1 h after a successful spontaneous breathing trial reduces reintubation in critically ill patients: a multicenter randomized controlled trial", Intensive Care Med, 542-543, 2018
  28. Appendicitis complicated by appendiceal metastasis via peritoneal dissemination from lung cancer, Respirol Case Rep., 2016
  29. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), J Intensive Care, 20210825
  30. A Novel Microcontroller-Based System for the Wheel-Running Activity in Mice, ENEURO, 8(6), 2021
    Link to Paper Search Results by DOI
  31. Differential Effectiveness of Hypothermic Targeted Temperature Management According to the Severity of Post-Cardiac Arrest Syndrome, JOURNAL OF CLINICAL MEDICINE, 10(23), 202112
    Link to Paper Search Results by DOI
  32. Short- versus prolonged-course antibiotic therapy for sepsis or infectious diseases in critically ill adults: a systematic review and meta-analysis, INFECTIOUS DISEASES, 54(3), 213-223, 20220304
    Link to Paper Search Results by DOI

Invited Lecture, Oral Presentation, Poster Presentation

  1. Low serum zonulin concentrations are associated with an unfavorable outcome in patients with sepsis, Kazuya Kikutani, Nobuaki Shime, Mitsuaki Nishikimi, Kohei Ota, Miyuki Hattori, Shinichiro Ohshimo, 2nd Joint Scientific Congress of JSICM/TSCCM, 2023/10/14, Without Invitation, English
  2. Increase in Burden of Patients With Severe COVID-19 Nationwide Was Associated With Higher Mortality Rate of Patients With COVID-19 Requiring Mechanical Ventilation: An Observational Study of a National Database in Japan, Kazuya Kikutani, Mitsuaki Nishikimi, Shinichiro Ohshimo, Nobuaki Shime, Kazuya Kikutani, Mitsuaki Nishikimi, Shinichiro Ohshimo, Nobuaki Shime, 2023/05/24, Without Invitation, Japanese
  3. Quantification of respiratory sounds by continuous monitoring system can be used to predict complications after extubation: A pilot study, Kazuya Kikutani, Shinichiro Ohshimo, Takuma Sadamori, Shingo Ohki, Hiroshi Giga, Junki Ishii, Hiromi Miyoshi, Kohei Ota, Nobuaki Shime, The 22nd KSCCM-JSICM Joint Congress, 2022, Without Invitation, English
  4. Utility of continuous monitoring and visualizing system for respiratory sounds., Kazuya Kikutani, Shinichiro Ohshimo, Takuma Sadamori, Hiroshi Giga, Shingo Ohki, Satoshi Yamaga, Nobuaki Shime :, Without Invitation, English
  5. Characteristics of wound infections among patients injured during torrential rain and landslides, in the 2018 disaster in West Japan,, Kazuya Kikutani, Michihito Kyo, Junji Itai, Shinji Kusunoki, Takao Yamanoue, Yasumasa Iwasaki, Itsuo Nakagawa, Hiroshi Naito, Masami Ishikawa, Nobuaki Shime:, Without Invitation, English

Awards

  1. 2024/02/18, Roche Infectious Disease Award 2023, Roche Diagnostics
  2. 2024/03/15, Encouragement award 2023 from the Japanese Society of Intensive Care Medicine, 日本集中治療医学会, Genetic deletion of translocator protein exacerbates post-sepsis syndrome with activation of the C1q pathway in septic mouse model.
  3. 2023/10/14, Outstanding E-Poster Awards, Joint Congress of JSICM/TSCCM/TSECCM, Joint Congress of JSICM/TSCCM/TSECCM
  4. Excellent Abstract Award, 22nd KSCCM-JSICM Joint Congress, Quantification of respiratory sounds by a continuous monitoring system can be used to predict complications after extubation: A pilot study

External Funds

Acceptance Results of Competitive Funds

  1. 2022, 2024

Social Activities

History as Committee Members

  1. Crisis Management Committee

History as Peer Reviews of Academic Papers

  1. 2025, Journal of Intensive Care, 2
  2. 2024, Journal of Intensive Care, Others, reviewer 1
  3. 2024, Cureus, Others, reviewer
  4. 2024, Journal of Intensive Care, Others, reviewer5
  5. 2024, Journal of Intensive Care, Others, reviewer1
  6. 2023, Acute Medicine & Surgery, reviewer 2
  7. 2023, Scientific Reports, Others, reviewer 2