SHOTA ITO

Last Updated :2026/07/03

Affiliations, Positions
Hiroshima University Hospital, Assistant Professor
E-mail
shota0313hiroshima-u.ac.jp
Other Contact Details
Kasumi 1-2-3, Minamiku, Hiroshima, Japan, Japan
TEL : (+81)82-257-5686 FAX : (+81)82-257-5687
Self-introduction
I am specializing in orthodontics.

Basic Information

Major Professional Backgrounds

  • 2023/04/01, Hiroshima University, Division of Oral Health and Development, Department of Orthodontics, Assistant Professor

Academic Degrees

  • Hiroshima University

In Charge of Primary Major Programs

  • Dentistry

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Orthodontics / Pediatric dentistry

Research Keywords

  • Orthodontics, microRNA, AI

Affiliated Academic Societies

  • The Japanese Society for Temporomandibular Joint
  • Japan academy of digital dentistry, 2020
    Related URL
  • CHU-SHIKOKU Orthodontic Society, 2016
    Related URL
  • Japanese Orthodontic Society, 2016
    Related URL

Educational Activity

Course in Charge

  1. 2026, Undergraduate Education, First Semester, Dental Research Practices I
  2. 2026, Undergraduate Education, 3Term, Basic Practice of Orthodontics I
  3. 2026, Undergraduate Education, 4Term, Basic Practice of Orthodontics II
  4. 2026, Undergraduate Education, Second Semester, Dental Research Practices II
  5. 2026, Undergraduate Education, First Semester, Dental Research Practices III
  6. 2026, Undergraduate Education, Year, Clinical Practice (Preventive Dentistry)
  7. 2026, Undergraduate Education, Year, Clinical Practice (Orthodontics)
  8. 2026, Undergraduate Education, 1Term, Orthodontics
  9. 2026, Undergraduate Education, Second Semester, Clinical Practice on Oral Health
  10. 2026, Undergraduate Education, Intensive, Clinical Practice on Oral Health
  11. 2026, Undergraduate Education, Intensive, Clinical Practice on Oral Health Management
  12. 2026, Undergraduate Education, 1Term, Orthodontics
  13. 2026, Undergraduate Education, 3Term, Practice of Orthodontics I
  14. 2026, Undergraduate Education, 4Term, Practice of Orthodontics II
  15. 2026, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Orthodontics and Craniofacial Developmental Biology
  16. 2026, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Orthodontics and Craniofacial Developmental Biology
  17. 2026, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Orthodontics and Craniofacial Developmental Biology
  18. 2026, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Orthodontics and Craniofacial Developmental Biology
  19. 2026, Graduate Education (Doctoral Program) , First Semester, Training Course for Orthodontic Specialist
  20. 2026, Graduate Education (Doctoral Program) , Second Semester, Training Course for Orthodontic Specialist

Research Activities

Academic Papers

  1. Sost deficiency restores calvarial bone thickness without recovery of sutural growth in Runx2 missense mutant mice, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 818, 20260618
    Link to Paper Search Results by DOI
  2. Age Estimation from Lateral Cephalograms Using Deep Learning: A Pilot Study from Early Childhood to Older Adults, JOURNAL OF CLINICAL MEDICINE, 14(19), 20251007
    Link to Paper Search Results by DOI
  3. Detecting the articular disk in magnetic resonance images of the temporomandibular joint using YOLO series, DENTAL MATERIALS JOURNAL, 44(1), 103-111, 202502
    Link to Paper Search Results by DOI
  4. Role of Extracellular Vesicles of Stem Cells from Human Exfoliated Deciduous Teeth in Osteogenesis, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 26(12), 20250618
    Link to Paper Search Results by DOI
  5. Effects of recombinant human sclerostin on proliferation and migration in human cementoblast lineage cells, ARCHIVES OF ORAL BIOLOGY, 175, 202507
    Link to Paper Search Results by DOI
  6. RadImageNet and ImageNet as Datasets for Transfer Learning in the Assessment of Dental Radiographs: A Comparative Study, JOURNAL OF IMAGING INFORMATICS IN MEDICINE, 38(1), 534-544, 202502
    Link to Paper Search Results by DOI
  7. ★, Prediction of a Cephalometric Parameter and Skeletal Patterns from Lateral Profile Photographs: A Retrospective Comparative Analysis of Regression Convolutional Neural Networks, JOURNAL OF CLINICAL MEDICINE, 13(21), 202411
    Link to Paper Search Results by DOI
  8. Sex estimation from maxillofacial radiographs using a deep learning approach, DENTAL MATERIALS JOURNAL, 43(3), 202406
    Link to Paper Search Results by DOI
  9. Image preprocessing with contrast-limited adaptive histogram equalization improves the segmentation performance of deep learning for the articular disk of the temporomandibular joint on magnetic resonance images, ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 138(1), 128-141, 202407
    Link to Paper Search Results by DOI
  10. The expression of MIR125B transcripts and bone phenotypes in Mir125b2-deficient mice, PLOS ONE, 19(7), 20240708
    Link to Paper Search Results by DOI
  11. Surgical Orthodontic Treatment for Skeletal Maxillary Protrusion in Sturge-Weber Syndrome: A Case Report and Review of the Literature, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(5), 20240509
    Link to Paper Search Results by DOI
  12. Image preprocessing with contrast-limited adaptive histogram equalization improves the segmentation performance of deep learning for the articular disk of the temporomandibular joint on magnetic resonance images, Oral Radiol., 2023
  13. High-frequency near-infrared semiconductor laser irradiation suppressed experimental tooth movement-induced inflammatory pain markers in the periodontal ligament tissues of rats, Lasers Med Sci, 20230420
  14. Effect of Er: YAG Laser Irradiation on Bone Metabolism-Related Factors Using Cultured Human Osteoblasts, JOURNAL OF LASERS IN MEDICAL SCIENCES, 14, 20230330
    Link to Paper Search Results by DOI
  15. High-frequency near-infrared semiconductor laser irradiation suppressed experimental tooth movement-induced inflammatory pain markers in the periodontal ligament tissues of rats, LASERS IN MEDICAL SCIENCE, 38(1), 20230420
    Link to Paper Search Results by DOI
  16. The matrix vesicle cargo miR-125b accumulates in the bone matrix, inhibiting bone resorption in mice., Commun Biol, 3(1), 30, 2020
  17. Landmark annotation and mandibular lateral deviation analysis of posteroanterior cephalograms using a convolutional neural network., J Dent Sci, 16(3), 957-963, 2020
  18. ANGPTL2 Induces Synovial Inflammation via LILRB2., Inflammation, 44(3), 1108-1118, 2021
  19. ★, Overexpression of miR-125b in Osteoblasts Improves Age-Related Changes in Bone Mass and Quality Through Suppression of Osteoclast Formation., Int J Mol Sci, 22(13), 6745, 2021
  20. High-frequency near-infrared diode laser irradiation suppresses IL-1beta-induced inflammatory cytokine expression and NF-kB signaling pathways in human primary chondrocytes., Lasers Med Sci, 37(2), 1193-1201, 2021
  21. ★, Automated segmentation of articular disc of the temporomandibular joint on magnetic resonance images using deep learning., Sci Rep, 12(1), 221, 2022
  22. Effects of high-frequency near infrared laser irradiation on experimental tooth movement-induced pain in rats., Lasers Med Sci, 37(6), 2697-2706, 2022
  23. Longitudinal effects of estrogen on mandibular growth and changes in cartilage during the growth period in rats., Dev Biol, 492, 126-132, 2022
  24. Effect of Er: YAG laser irradiation on bone metabolism-related factors using cultured human osteoblasts: Examination of the effect of Er: YAG laser irradiation using osteoblast., J Lasers Med Sci, 2022

Invited Lecture, Oral Presentation, Poster Presentation

  1. Determining the impacted state of maxillary canines in panoramic radiographs using deep learning, Yoshimi Y., Mine Y., Takeda S., Okazaki S., Ogawa S., Ito S., Murayama T., Tanimoto K, The 38th Annual Meeting of Taiwan Association of Orthodontists, 2025/11/06, Without Invitation, English
  2. Renal dysfunction contributes to decreased bone turnover in the temporomandibular joint, YoshidaM., Yanoshita M., Hirose N., Kita D., Kubo N., Ogata S., Ito S., Tanimoto K, The 38th Annual Meeting of Taiwan Association of Orthodontists, 2025/11/06, Without Invitation, English
  3. A Case of Klippel-Feil Syndrome: Analysis of Oral and Maxillofacial Findings and Treatment Approach, Ito S., Abe F.,Yoshimi Y., Kado I., Koizumi Y., Ogasawara T., Hirose N., Tanimoto K, The15th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies, 2025/10/23, Without Invitation, Japanese
  4. Analysis of the effect of miR-125b-1 on bone metabolism, Ito S., Ohgashira S., OshiroR., Kunimatsu R., Tanimoto K, IADR Asia Pacific Regional & 35th ISDR Annual Conference 2025, 2025/09/20, Without Invitation, English
  5. Multimodal AI-based prediction of skeletal pattern from lateral facial photographs, Ito S., Mine Y.,Yoshimi Y., Okazaki S., Ogawa S., Takeda S., Murayama T., Tanimoto K, IADR Asia Pacific Regional & 35th ISDR Annual Conference 2025, 2025/09/20, Without Invitation, English
  6. Bone matrix miR-125b inhibits bone resorption without affecting skeletal development and improves agerelated changes in bone mass and quality., Ito S, Minamizaki T, Kitaura Y, Ohba S, Chung U, Tanimoto K, and Yoshiko Y, ASBMR 2019 Annual Meeting, 2019, Without Invitation, Japanese
  7. MicroRNA-125b embedded in bone matrix exerts protective effects on ovariectomy- and neurectomy-induced bone loss by suppressing osteoclast formation., Minamizaki T, Ahmed F, Sarmin N, Ito S, Tanimoto K, and Yoshiko Y, The World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases – the International Osteoporosis Foundation – the European society for Clinical and Economic Aspects of Osteoarthritis 2019, 2019, Without Invitation, English
  8. MicroRNA-125b derived from osteoblasts exerts its anti-osteolytic effect through targeting preosteoclasts., Ahmed F, Minamizaki T, Ito S, Sarmin N, Fujimoto C, Nakano Y, Tanimoto K, Hiyama S, and Yoshiko Y, ASBMR 2017 Annual Meeting, 2017, Without Invitation, English

Awards

  1. ASBMR 2019 Annual Meeting Young Investigator Award, ASBMR, Bone matrix miR-125b inhibits bone resorption without affecting skeletal development and improves agerelated changes in bone mass and quality
  2. ASBMR 2019 Annual Meeting Plenary Poster, ASBMR, Bone matrix miR-125b inhibits bone resorption without affecting skeletal development and improves agerelated changes in bone mass and quality

External Funds

Acceptance Results of Competitive Funds

  1. 2025/04, 2028/03
  2. 2023/04, 2026/03
  3. 2025, 2026
  4. 2022, 2024