広島大学

Basic Information

Major Professional Backgrounds

• 2016/04, 2018/03, Japan Society for the Promotion of Science
• 2018/04/01, 2019/03/31, Hiroshima University, Graduate School of Biosphere Science, Assistant Professor
• 2019/04/01, Hiroshima University, Graduate School of Integrated Sciences for Life, Assistant Professor

Educational Backgrounds

• Shinshu University, Japan, 2015/04, 2018/03
• Shinshu University, Japan, 2013/04, 2015/03
• Shinshu University, Japan, 2009/04, 2013/03

Academic Degrees

• Shinshu University
• Shinshu University

Research Fields

• Agricultural sciences;Animal life science;Integrative animal science
• Agricultural sciences;Agricultural chemistry;Food science
• Biology;Biological Science;Molecular biology

Research Keywords

• Oligodeoxynucleotide
• Lactic acid bacteria
• Maternal immunity
• Fermentation
• Functional food
• sepsis
• neonatal disease
• Allergy
• mouse

Affiliated Academic Societies

• Japan Society for Bioscience, Biotechnology, and Agrochemistry
• Japanese Society of Animal Science
• Japanese Association for Food Immunology
• Japanese Dairy Science Association
• Japan Society of Nutrition and Food Science

Educational Activity

Course in Charge

1. 2020, Liberal Arts Education Program1, 4Term, Biological production and natural environment
2. 2020, Liberal Arts Education Program1, 3Term, Food safety and health science
3. 2020, Undergraduate Education, 2Term, Reading of Foreign Literature
4. 2020, Undergraduate Education, 4Term, Introduction to Applied Biological Science II
5. 2020, Undergraduate Education, Intensive, Laboratory Work in Food Chemistry
6. 2020, Undergraduate Education, Academic Year, Graduation Thesis
7. 2020, Undergraduate Education, 3Term, Research Front of Applied Biological Science
8. 2020, Undergraduate Education, 1Term, Food Function (Functional Food Science)
9. 2020, Undergraduate Education, Intensive, Training for Animal Food Processing
10. 2020, Graduate Education (Master's Program) , 1Term, Special Lectures in Integrated Sciences for Life

Research Activities

Academic Papers

1. Fermentable fibers upregulate suppressor of cytokine signaling1 in the colon of mice and intestinal Caco-2 cells through butyrate production, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2020
2. Oral Administration of Flavonifractor plautii Strongly Suppresses Th2 Immune Responses in Mice, FRONTIERS IN IMMUNOLOGY, 11, 2020
3. Naringenin promotes recovery from colonic damage through suppression of epithelial tumor necrosis factor-α production and induction of M2-type macrophages in colitic mice., Nutrition research (New York, N.Y.), 64, 2019
4. Exopolysaccharides from Leuconostoc mesenteroides attenuate chronic kidney disease in mice by protecting the intestinal barrier, JOURNAL OF FUNCTIONAL FOODS, 52, 276-283, 201901
   Link to Paper Search Results by DOI
5. Recombinant mouse calcitonin gene-related peptide secreted by Lactococcus lactis inhibits lipopolysaccharide-induced inflammatory response in macrophages., Animal science journal = Nihon chikusan Gakkaiho, 2018
6. Recombinant Mouse Osteocalcin Secreted by Lactococcus lactis Promotes Glucagon-Like Peptide-1 Induction in STC-1 Cells., Current microbiology, 75(1), 2018
7. Immune synergistic oligodeoxynucleotide from Lactobacillus rhamnosus GG enhances the immune response upon co-stimulation by bacterial and fungal cell wall components., Animal science journal = Nihon chikusan Gakkaiho, 89(10), 2018
8. Secretion of an immunoreactive single-chain variable fragment antibody against mouse interleukin 6 by Lactococcus lactis., Applied microbiology and biotechnology, 101(1), 2017
9. Synergistic oligodeoxynucleotide strongly promotes CpG-induced interleukin-6 production., BMC immunology, 18(1), 2017
10. ★, Class A CpG Oligonucleotide Priming Rescues Mice from Septic Shock via Activation of Platelet-Activating Factor Acetylhydrolase., Frontiers in immunology, 8, 2017
11. Genetically modified Lactococcus lactis producing a green fluorescent protein-bovine lactoferrin fusion protein suppresses proinflammatory cytokine expression in lipopolysaccharide-stimulated RAW 264.7 cells., Journal of Dairy Science
12. ★, Development of a simple IgE-independent anaphylactic model using buckwheat antigen and B-type CpG oligodeoxynucleotide from Streptococcus thermophilus., Animal science journal = Nihon chikusan Gakkaiho, 87(5), 2016
13. Oral delivery of Lactococcus lactis that secretes bioactive heme oxygenase-1 alleviates development of acute colitis in mice., Microbial cell factories, 14, 2015
14. ★, Inhibitory/suppressive oligodeoxynucleotide nanocapsules as simple oral delivery devices for preventing atopic dermatitis in mice., Molecular therapy : the journal of the American Society of Gene Therapy, 23(2), 2015
15. Generation of dipeptidyl peptidase-IV-inhibiting peptides from β-lactoglobulin secreted by Lactococcus lactis., BioMed research international, 2014, 2014

Social Activities

History as Peer Reviews of Academic Papers

1. 2019, Bioscience, Biotechnology, and Biochemistry, Others, 1