Masanori Ito

Last Updated :2023/01/06

Affiliations, Positions
Hiroshima University Hospital(Medical), Professor

Basic Information

Major Professional Backgrounds

  • 2007/07/01, 2016/03/31, Hiroshima University, Hospital, Lecturer
  • 1994/04/01, 1996/05/31, Saiseikai Kure Hospital
  • 1996/06/01, 2000/05/31, Medical Corporation JR Hiroshima Hospital
  • 2000/06/01, 2002/09/30, Hiroshima University, Health Service Center, Research Associate
  • 2002/10/01, 2007/06/30, Hiroshima University Hospital, Research Associate
  • 2016/04/01, 2019/03/31, Hiroshima University, Institute of Biomedical & Health Sciences, Associate Professor
  • 2019/04/01, Hiroshima University, Graduate School of Biomedical & Health Sciences, Associate Professor
  • 2019/10/01, Hiroshima University, Graduate School of Biomedical & Health Sciences, Professor

Educational Backgrounds

  • Hiroshima University, Graduate School, Division of Medical Sciences, Japan, 1988/04, 1992/03
  • Hiroshima University, Faculty of Medicine, Japan, 1982/04, 1988/03

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
  • [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine

In Charge of Primary Major Programs

  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Gastroenterology

Research Keywords

  • gastric cancer
  • gastritis

Educational Activity

Course in Charge

  1. 2022, Undergraduate Education, Second Semester, Human Relations
  2. 2022, Undergraduate Education, Intensive, Practice for medical research
  3. 2022, Undergraduate Education, Intensive, Practice of Medicine I
  4. 2022, Undergraduate Education, Intensive, Practice of Medicine II
  5. 2022, Graduate Education (Master's Program) , First Semester, Research on Public Health (Health Service Administration)
  6. 2022, Graduate Education (Master's Program) , Second Semester, Research on Public Health (Health Service Administration)
  7. 2022, Graduate Education (Master's Program) , Second Semester, Lecture on Practice of General Medicine
  8. 2022, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on General Medicine
  9. 2022, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on General Medicine
  10. 2022, Graduate Education (Doctoral Program) , First Semester, Advanced Research on General Medicine
  11. 2022, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on General Medicine

Research Activities

Academic Papers

  1. A Case of Bazex Syndrome, Intern Med, 61(3), 443-444, 2021
  2. Evidence-based clinical practice guidelines for peptic ulcer disease 2020, J Gastroenterol, 56(4), 303-322, 2021
  3. Helicobacter pylori dupA and gastric acid secretion are negatively associated with gastric cancer development, JOURNAL OF MEDICAL MICROBIOLOGY, 59(12), 1484-1489, 201012
  4. Low Prevalence of Helicobacter pylori-negative Gastric Cancer among Japanese, HELICOBACTER, 16(6), 415-419, 201112
  5. Evaluation of Individual Risk in Nonvariceal Gastrointestinal Bleeding Patients with NSAID Administration: A Multicenter Study in Japan, DIGESTION, 86(3), 187-193, 2012
  6. Gastric Cancer Development after Helicobacter pylori Eradication Therapy: A New Form of Gastric Neoplasia, DIGESTION, 85(1), 61-67, 2012
  7. Serum screening for detection of high-risk group for early-stage diffuse type gastric cancer in Japanese, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(3), 598-602, 201203
  8. Efficacy of adding sodium alginate to omeprazole in patients with nonerosive reflux disease: a randomized clinical trial, DISEASES OF THE ESOPHAGUS, 25(5), 373-380, 201207
  9. High Expression of Gastrin Receptor Protein in Injured Mucosa of Helicobacter pylori-Positive Gastritis, DIGESTIVE DISEASES AND SCIENCES, 58(3), 634-640, 201303
  10. The effect of Helicobacter pylori eradication therapy on gastric ulcer healing after endoscopic mucosal resection, J Clin Gastroenterol, 40(4), 293-296, 20060401
  11. Expression of cell cycle regulators and growth factor/receptor systems in gastric carcinoma in young adults: Association with Helicobacter pylori infection, Int. J. Molecular Med., 5: 185-190, 20000101
  12. Changing pattern of gastric cancer in Japan, 2nd International Gastric Cancer Congress= Munich, 19970612
  13. Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with nalysis of p53 and K-ras alteration and microsatellite instability, Int J Oncol, 18, 1207-1212, 20010401
  14. Microsatellite instability at D18S61 is associated with no regression of gastric mucosa-associated lymphoid tissue lymphoma after Helicobacter pylori eradication, Oncol.Rep., 8, 293-297, 20010401
  15. Reduction in the incidence of Helicobacter pylori-associated carcinoma in Japanese young adalts, Oncol.Rep., 8, 633-636, 20010401
  16. Effect of long-term half-dose famotidine therapy on corpus gastritis in peptic ulcer desease.;, Aliment Pharmacol Ther, 21, 99-104, 20050101
  17. Corrrespondence, Dig Liver Dis, 37, 982, 20051201
  18. Surface structure of antral gastric mucosa represents the status of histologic gastritis: fundamental evidence for the evaluation of antral gastritis by magnifying endoscopy., J Gastroenterol Hepatol, 21, 837-841, 20060501
  19. Biomarkers in patients with gastic inflammation: a systematic review., Digestion, 72, 164-180, 20050401
  20. Causal role of Helicobacter pylori infection and eradication therapy in gastric carcinogenesis., World J Gastroenterol, 12(1), 10-16, 20060101
  21. Angiogenic switch occurs during the precancerous stage of human esophageal squamous cell carcinoma, Oncol Rep, 11, 315-319, 20040401
  22. Chromosomal and microsatellite instability in sporadic gastric cancer, J Gastroenterol Hepatol, 19, 756-760, 20040501
  23. Chronic gastritis with expression of inducible nitric oxide synthase is associated with high expression of interleukin-6 and hypergastrinaemia, Aliment Pharmacol Ther, 19, 1309-1314, 20040401
  24. Clinical features of gastric cancer discovered after successful eradication of Helicobacter pylori: results from a 9-year prospective follow-up study in Japan, Aliment Pharmacol Ther, 21, 1121-1126, 20050501
  25. Clinical significance of angiopoietin-2 expression at the deepest invasive tumor site of advanced colorectal carcinoma, Int J Oncol, 24, 539-547, 20040201
  26. Clinicopathologic and endoscopic features of colorectal serrated adenoma:differences between polypoid and superficial types, Gastrointest Endosc, 59(2), 213-219, 20040201
  27. Clinicopathologic features and endoscopic resection of early primary nonampullary duodenal carcinoma, J Clin Gastroenterol, 37(5), 381-386, 20040501
  28. Development of a novel method to detect Helicobacter pylori cagA genotype from paraffin-embedded materials: comparison between patients with duodenal ulcer and gastric cancer in young Japanese, Digestion, 73, 47-53, 20060401
  29. Effect of long-term half-dose famotidine therapy on corpus gastritis in peptic ulcer disease, Aliment Pharmacol Ther, 21, 99-104, 20050601
  30. Eradication of Helicobacter pylori increases the incidence of hyperlipidaemia and obesity in peptic ulcer patients, Dig Liver Dis, 37, 39-43, 20050101
  31. Frequent loss of heterozygosity on chromosome 10p14-p15 in esophageal dysplasia and squamous cell carcinoma, Oncol Rep, 12, 333-337, 20040401
  32. Helicobacter pylori infection is the major risk factor for gastric inflammation in the cardia, Dig Dis Sci, 51, 1582-1588, 20060901
  33. Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma, Pathobiology, 72, 220-224, 20050901
  34. Lymphatic vessel density at the site of deepest penetration as a predictor of lymph node metastasis in submucosal colorectal cancer, Dis Colon Rectum, 50(1), 13-21, 20060101
  35. Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation, Inflamm Bowel Dis, 10(6), 737-744, 20040601
  36. Magnifying gastroendoscopy for diagnosis of histologic gastritis in the gastric antrum, Dig Liver Dis, 36, 286-291, 20040401
  37. Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia, J Gastroenterol Hepatol, 22, 304-310, 20070301
  38. Morphological changes in human gastric tumours after eradication therapy of Helicobacter pylori in a short-term follow-up, Aliment Pharmacol Ther, 21, 559-566, 20050301
  39. Mucin phenotype and background mucosa of intramucosal differentiated-type adenocarcinoma of the stomach, Oncology, 66(8), 379-387, 20040401
  40. Relationship between histopathological features and type V pit pattern determined by magnifying videocolonoscopy in early colorectal carcinoma, Dig Endos, 17, 117-122, 20050401
  41. Immune response to cagA protein is associated with improved platelet count after Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura, Helicobacter, 12, 36-42, 20070201
  42. Host factors contributing to the discovery of gastric cancer after successful eradication therapy of Helicobacter pylori:preliminary report, J Gastroenterol Hepatol, 22, 571-576, 20070401
  43. Efficacy of rabeprazole on heartburn symptom resolution in patients with non-erosive and erosive gastro-oesophageal reflux disease: a multicenter study from Japan, Aliment Pharmacol Ther, 26, 677-679, 20070701
  44. Helicobacter pylori-associated gastritisis related to babA2expression without heterogeneity of the 3' region of the cagA genotype in Gastric Biopsy Specimens, Pathobiology, 74(5), 1-7, 20070401
  45. Treatment of functional dyspepsia with serotonin agonists: A meta-analysis of randomized controlled trials, J Gastroenterol Hepatol, 22, 1566-1570, 20071001
  46. Reduction in gastric cancer mortality by screening based on serum pepsinogen concentration: A case-control study, Scand J Gastroenterol, 42, 760-764, 20070601
  47. Role of Helicobacter pylori infection and chronic inflammation in gastric cancer in the cardia, Jpn J Clin Oncol, 37, 365-369, 20071213
  48. Reg IV is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapy., Oncogene, 26(30), 4383-4393, 20070701
  49. Serum concentration of Reg IV in patients with colorectal cancer: Overexpression and high Reg IV serum level is associated with liver metastasis., Oncology, IN PRESS, 20071201
  50. Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonography, J Gastroenterol, 43, 332-227, 20081201
  51. Role of the gastrin-gastrin receptor system in the expansive growth of human gastric neoplasms, Digestion, 78, 163-170, 20081201
  52. Evaluation of gastric cancer risk using topography of histological gastritis: a large-scaled cross-sectional study, Dig Dis Sci, 58, 1818-1823, 20091001
  53. Presence of poorly differentiated component correlated with submucosal invasion in the early diffuse-type gastric cancer., Hepato-Gastroenterology, 55, 2264-2268, 20091001
  54. A case of gastric adenocarcinoma arising from a fundic gland polyp, Clin J Gastroenterol, 2, 279-283, 20091001
  55. Ecabet sodium induces neuronal nitric oxide synthase-derived nitric oxide synthesis and gastric adaptive relaxation in the human stomach, J Gastroenterol, 44, 1118-1124, 20091101
  56. Infliximab treatment for Crohn's disease in a patient with IgA nephropathy, Clin J Gastroenterol, 2, 380-383, 20091201
  57. Histological evaluation of patients with gastritis at high risk of developing gastric cancer using a conventional index., Pathol Res Pract., 207(6), 354-358, 20110601
  58. A Water-soluble extract from culture medium of ganoderma lucidum mycelia suppresses the development of colorectal adenoma, Hiroshima J Med Sci, 59(1), 1月6日, 20100101
  59. Cheilitis granulomatosa as an early manifestation of Crohn's disease, Clin J Gastroenterol, 2, 190-193, 20090501
  60. Pathogenetic role of the tyrosine-phosphorylated CagA EPIYA sequence of Helicobacter pylori in histological gastritis in Japanese patients, J Gastroenterol, 44(5), 405-411, 20090501
  61. Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review, J Gastroenterol, 44(5), 365-371, 20090501
  62. Little necessity of acid inhibition against proton pump inhibitor rebound effects and prior Helicobacter pylori eradication therapy in gastric ulcer patients: a randomized prospective study, Hepatogastroenterology, 56(91-92), 624-628, 20090601
  63. Ecabet sodium induces neuronal nitric oxide synthase-derived nitric oxide synthesis and gastric adaptive relaxation in the human stomach, J Gastroenterol, 44(8), 1118-1124, 20090801
  64. Infliximab treatment for Crohn's disease in a patient with IgA nephropathy, Clin J Gastroenterol, 2, 380-383, 20091001
  65. Plaunotol induces a comparative increase of acidic mucin fraction in gastric juice, Hepatogastroenterology, 58(106), 663-668, 20110301
  66. Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis., Dig Dis Sci., 47(4), 862-867, 20020401
  67. p53 Codon 72 polymorphism in gastric cancer susceptibility in patients with Helicobacter pylori-associated chronic gastritis., Int J Cancer., 100(3), 304-308, 20020701
  68. Helicobacter pylori eradication therapy improves atrophic gastritis and intestinal metaplasia: a 5-year prospective study of patients with atrophic gastritis., Aliment Pharmacol Ther., 16(8), 1449-1456, 20020801
  69. Implication of anti-parietal cell antibody levels in gastrointestinal diseases, including gastric carcinogenesis., Dig Dis Sci., 47(5), 1080-1085, 20020501
  70. Role of anti-parietal cell antibody in Helicobacter pylori-associated atrophic gastritis: evaluation in a country of high prevalence of atrophic gastritis., Scand J Gastroenterol., 37(3), 287-293, 20020301
  71. Serological comparison of serum pepsinogen and anti-parietal cell antibody levels between Japanese and German patients., Eur J Gastroenterol Hepatol., 14(2), 123-127, 20020201
  72. Single administration of ecabet sodium diminishes the level of delta-13CO2 in urea breath test., J Gastroenterol., 37(8), 674-675, 20020801
  73. Microsatellite instability at D18S61 is associated with no regression of gastric mucosa-associated lymphoid tissue lymphoma after Helicobacter pylori eradication., Oncol Rep, 8(2), 293-7, 20010401
  74. c-myc gene mutation in gastric mucosa-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma, Oncol Rep, 8(2), 289-92, 20010401
  75. Reduction in the incidence of Helicobacter pylori-associated carcinoma in Japanese young adults, Oncol Rep, 8(3), 633-6, 20010501
  76. Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with analysis of p53 and K-ras alteration and microsatellite instability, Int J Oncol, 18(6), 1207-12, 20010601
  77. Helicobacter pylori infection is a major risk factor for gastric carcinoma in young patients, Scand J Gastroenterol, 35(3), 255-259, 20000301
  78. Enhanced expression of inducible Nitric Oxide Synthase and Nitrotyrosine in gastric mucosa of gastric cancer patients, Clin Cancer Res, 5(6), 1411-5., 19990601
  79. Reduced levels of transforming growth factor-beta type I receptor in human gastric carcinomas., Jpn J Cancer Res, 83(1), 86-92, 19920101
  80. New prognostic factors in human gastric carcinomas, 19(1), 26-33, 20010101
  81. monoclonal antibody capable of detecting new differentiation antigen of the stomach, Int J Cancer, 50(4), 523-7, 19920201
  82. Expression of several growth factors and their receptor genes in human colon carcinomas, Virchows Arch B Cell Pathol Incl Mol Pathol., 59(3), 173-178, 19900401
  83. Minute carcinoid arising in gastric tubular adenoma, Histopathology., 15(1), 96-99, 19890701
  84. Epidermal growth factor induces the expression of its receptor gene in human gastric carcinoma cell line TMK-1, Jpn J Cancer Res, 80(8), 743-746, 19890801
  85. Cytogenetical analysis of the human gastric carcinoma cell line TMK-1, Hiroshima J Med Sci, 38(3), 121-124, 19890901
  86. Reduced tumorigenicity and cell motility of a gastric-carcinoma cell-line by introduction of wild-type p53 gene., Int J Oncol, 3(2), 265-71, 19930801
  87. Papillary adenoma of the stomach. Pathologic and immunohistochemical study., Arch Pathol Lab Med., 113(9), 1030-4, 19890901
  88. Expression of several growth factors and their receptor genes in human colon carcinomas., Virchows Arch B Cell Pathol Incl Mol Pathol, 59(3), 173-8., 19900101
  89. Advanced method for evaluation of gastric cancer risk by serum markers: determination of true low-risk subjects for gastric neoplasm, Helicobacter, 19(1), 1-8, 20140201
  90. Reduction in the incidence of Helicobacter pylori-associated carcinoma in Japanese young adults, ONCOLOGY REPORTS, 8(3), 633-636, 2001
  91. Role of anti-parietal cell antibody in Helicobacter pylori-associated atrophic gastritis: Evaluation in a country of high prevalence of atrophic gastritis, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37(3), 287-293, 200203
  92. Serological comparison of serum pepsinogen and antiparietal cell antibody levels between Japanese and German patients, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 14(2), 123-127, 200202
  93. Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis, DIGESTIVE DISEASES AND SCIENCES, 47(4), 862-867, 200204
  94. Implication of anti-parietal cell antibody levels in gastrointestinal diseases, including gastric carcinogenesis, DIGESTIVE DISEASES AND SCIENCES, 47(5), 1080-1085, 200205
  95. p53 codon 72 polymorphism in gastric cancer susceptibility in patients with Helicobacter pylori-associated chronic gastritis, INTERNATIONAL JOURNAL OF CANCER, 100(3), 304-308, 20020720
  96. Significance of an exaggerated meal-stimulated gastrin response in pathogenesis of Helicobacter pylori-negative duodenal ulcer, DIGESTIVE DISEASES AND SCIENCES, 48(4), 644-651, 200304
  97. Expression of hypoxia-inducible factor-l alpha is associated with tumor vascularization in human colorectal carcinoma, INTERNATIONAL JOURNAL OF CANCER, 105(2), 176-181, 20030610
  98. Isolated granulomatous gastritis successfully treated by Helicobacter pylori eradication: a possible association between granulomatous gastritis and Helicobacter pylori, JOURNAL OF GASTROENTEROLOGY, 38(4), 371-375, 200304
  99. Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 12(2), 169-174, 200308
  100. Review article: clinical significance of mucosal-protective agents: acid, inflammation, carcinogenesis and rebamipide, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 18, 153-159, 200307
  101. Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 12(4), 437-442, 200310
  102. Helicobacter pylori infection influences expression of genes related to angiogenesis and invasion in human gastric carcinoma cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 311(4), 809-814, 20031128
  103. Involvement of proinflammatory cytokines IL-1 beta and IL-6 in progression of human gastric carcinoma, ANTICANCER RESEARCH, 25(2A), 709-713, 2005
  104. Magnifying gastroendoscopy for diagnosis of histologic gastritis in the gastric antrum, DIGESTIVE AND LIVER DISEASE, 36(4), 286-291, 200404
  105. Chronic gastritis with expression of inducible nitric oxide synthase is associated with high expression of interleukin-6 and hypergastrinaemia, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 19(12), 1309-1314, 20040615
  106. A combination of the Helicobacter pylori stool antigen test and urea breath test is useful for clinical evaluation of eradication therapy: A multicenter study, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(8), 1241-1245, 200508
  107. Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation, INFLAMMATORY BOWEL DISEASES, 10(6), 737-744, 200411
  108. Eradication of Helicobacter pylori increases the incidence of hyperlipidaemia and obesity in peptic ulcer patients, DIGESTIVE AND LIVER DISEASE, 37(1), 39-43, 200501
  109. Morphological changes in human gastric tumours after eradication therapy of Helicobacter pylori in a short-term follow-up, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21(5), 559-566, 20050301
  110. Clinical features of gastric cancer discovered after successful eradication of Helicobacter pylori: results from a 9-year prospective follow-up study in Japan, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21(9), 1121-1126, 20050501
  111. Effect of long-term half-dose famotidine therapy on corpus gastritis in peptic ulcer disease, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 21, 99-104, 200506
  112. Cardiac glands hyperplastic polyp of the stomach, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 20(9), 1461-1463, 200509
  113. Biomarkers in patients with gastric inflammation: A systematic review, DIGESTION, 72(2-3), 164-180, 2005
  114. Evaluation of an ELISA for detection of anti-parietal cell antibody, HEPATO-GASTROENTEROLOGY, 53(67), 11-14, 2006
  115. The effect of Helicobacter pylori eradication therapy on gastric ulcer healing after endoscopic mucosal resection, JOURNAL OF CLINICAL GASTROENTEROLOGY, 40(4), 293-296, 200604
  116. Development of a novel method to detect Helicobacter pylori cagA genotype from paraffin-embedded materials: Comparison between patients with duodenal ulcer and gastric cancer in young Japanese, DIGESTION, 73(1), 47-53, 2006
  117. Surface structure of antral gastric mucosa represents the status of histologic gastritis: Fundamental evidence for the evaluation of antral gastritis by magnifying endoscopy, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 21(5), 837-841, 200605
  118. Anti-parietal cell antibody and serum pepsinogen assessment in screening for gastric carcinoma, DIGESTIVE AND LIVER DISEASE, 38(5), 303-307, 200605
  119. A case of Crohn's disease with hydronephrosis caused by ureteropelvic junction obstruction, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 18(9), 1015-1018, 200609
  120. Helicobacter pylori infection is the major risk factor for gastric inflammation in the cardia, DIGESTIVE DISEASES AND SCIENCES, 51(9), 1582-1588, 200609
  121. Efficacy of rabeprazole on heartburn symptom resolution in patients with non-erosive and erosive gastro-oesophageal reflux disease: a multicenter study from Japan, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 26(1), 69-77, 20070701
  122. Serum pepsinogen levels in the Japanese population: Prospective study of 9 years of follow-up, HEPATO-GASTROENTEROLOGY, 54(78), 1887-1890, 200709
  123. Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonography, JOURNAL OF GASTROENTEROLOGY, 43(5), 332-337, 2008
  124. Evaluation of gastric cancer risk using topography of histological gastritis: A large-scaled cross-sectional study, DIGESTIVE DISEASES AND SCIENCES, 53(7), 1818-1823, 200807
  125. Role of the Gastrin-Gastrin Receptor System in the Expansive Growth of Human Gastric Neoplasms, DIGESTION, 78(2-3), 163-170, 2008
  126. Presence of Poorly Differentiated Component Correlated with Submucosal Invasion in the Early Diffuse-type Gastric Cancer, HEPATO-GASTROENTEROLOGY, 55(88), 2264-2268, 2008
  127. Relationship between Helicobacter pylori Tyrosine-Phosphorylated CagA-Related Markers and the Development of Diffuse-Type Gastric Cancers: A Case-Control Study, DIGESTION, 82(1), 10-17, 2010
  128. Plaunotol Induces a Comparative Increase of Acidic Mucin Fraction in Gastric Juice, HEPATO-GASTROENTEROLOGY, 58(106), 663-668, 2011
  129. Histological evaluation of patients with gastritis at high risk of developing gastric cancer using a conventional index, PATHOLOGY RESEARCH AND PRACTICE, 207(6), 354-358, 2011
  130. Helicobacter pylori cagA polymorphism and gastric inflammation: An international comparison between Japanese and Brazilian patients, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 46(9), 1051-1056, 201109
  131. Bile Acid Promotes Intestinal Metaplasia and Gastric Carcinogenesis, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 21(11), 2101-2107, 201211
  132. Predicting the efficacy of proton pump inhibitors in patients with non-erosive reflux disease before therapy using dual-channel 24-h esophageal pH monitoring, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 27(5), 899-906, 201205
  133. Histology of symptomatic gastroesophageal reflux disease: Is it predictive of response to proton pump inhibitors?, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 28(3), 479-487, 201303
  134. Changes in endoscopic findings of gastritis after cure of H.pylori infection: Multicenter prospective trial, DIGESTIVE ENDOSCOPY, 25(3), 264-273, 201305
  135. Relation between bile acid reflux into the stomach and the risk of atrophic gastritis and intestinal metaplasia: A multicenter study of 2283 cases, DIGESTIVE ENDOSCOPY, 25(5), 519-525, 201309
  136. Characteristics of Metachronous Gastric Tumors after Endoscopic Submucosal Dissection for Gastric Intraepithelial Neoplasms, GASTROENTEROLOGY RESEARCH AND PRACTICE, 2014
  137. Management and clinical outcomes of type I gastric carcinoid patients: Retrospective, multicenter study in Japan, DIGESTIVE ENDOSCOPY, 26(3), 377-384, 201405
  138. Characteristic Epithelium with Low-Grade Atypia Appears on the Surface of Gastric Cancer after Successful Helicobacter pylori Eradication Therapy, HELICOBACTER, 19(4), 289-295, 201408
  139. Advanced Method for Evaluation of Gastric Cancer Risk By Serum Markers: Determination of True Low-Risk Subjects for Gastric Neoplasm, HELICOBACTER, 19(1), 1-8, 201402
  140. Rebamipide Improves Chronic Inflammation in the Lesser Curvature of the Corpus after Helicobacter pylori Eradication: A Multicenter Study, BIOMED RESEARCH INTERNATIONAL, 2015
  141. Time Trends in Helicobacter pylori Infection and Atrophic Gastritis Over 40Years in Japan, HELICOBACTER, 20(3), 192-198, 201506
  142. Interobserver and intraobserver agreement for gastric mucosa atrophy, BMC GASTROENTEROLOGY, 15, 20150804
  143. Diagnosis of Helicobacter pylori-induced gastritis by serum pepsinogen levels, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 30(10), 1473-1477, 201510
  144. Time trends in Helicobacter pylori Infection and atrophic gastritis over 40 years in Japan, Helicobacter, 12193, 2015
  145. nterobserver and intraobserver agreement for gastric mucosa atrophy, BMC Gastroenterol, 15, 95, 2015
  146. Diagnosis of helicobacter pylori-induced gastritis by serum pepsinogen levels , J Gastroenterol Hepatol, 30(10), 1473-1477, 2015
  147. ate of unintended Helicobacter pylori eradication in the Vietnamese, Helicobacter, 20(2), 156-157, 2015
  148. Rebamipide improves chronic inflammation in the lesser curvature of the corpus after Helicobacter pylori eradication: a multicenter study, Gut, 64(9), 1353-1367, 2015
  149. Helicobacter pylori陰性胃癌, 消化器の臨床, 18(2), 133-136, 2015
  150. 酸分泌抑制薬の歴史, 日本医事新報No4751, 4751, 20-23, 2015
  151. Endoscopic findings of the gastric mucosa during long-term use of proton pump inhibitor - a multicenter study, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 52(8), 828-832, 2017
  152. Indications for Small-bowel Capsule Endoscopy in Patients with Chronic Abdominal Pain, INTERNAL MEDICINE, 56(12), 1453-1457, 2017
  153. Serological Evaluation of Gastric Cancer Risk Based on Pepsinogen and Helicobacter pylori Antibody: Relationship to Endoscopic Findings, DIGESTION, 95(4), 314-318, 2017
  154. Reduced human α-defensin 6 in noninflamed jejunal tissue of patients with crohn's disease, Inflamm Bowel Dis, 22(5), 1119-1128, 2016
  155. Characteristics of gastric cancer in negative test of serum anti-Helicobacter pylori antibody and pepsinogen test: a multicenter study, GASTRIC CANCER, 20(5), 764-771, 201709
  156. Clinical Significance of Reddish Depressed Lesions Observed in the Gastric Mucosa after Helicobacter pylori Eradication, DIGESTION, 98(1), 48-55, 2018
  157. Gastric Cancer with Submucosal Invasion after Successful Helicobacter pylori Eradication: A Propensity Score-Matched Analysis of Patients with Annual Patient Endoscopic Survey, DIGESTION, 99(1), 59-65, 2019
  158. Rectal Lymphoid Follicle Aphthous Lesions Frequently Progress to Ulcerative Colitis with Proximal Extension, INTERNAL MEDICINE, 58(5), 625-631, 2019
  159. Optimal Criteria and Diagnostic Ability of Serum Pepsinogen Values for Helicobacter pylori Infection, JOURNAL OF EPIDEMIOLOGY, 29(4), 147-154, 201904
  160. Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy, JOURNAL OF GASTROENTEROLOGY, 54(10), 907-915, 201910
  161. Potential of Helicobacter pylori-uninfected signet ring cell carcinoma to invade the submucosal layer, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 34(11), 1955-1962, 201911
  162. Clinical Usefulness of Dual Red Imaging in Gastric Endoscopic Submucosal Dissection: A Pilot Study, Clin Endosc, 53(1), 54-59, 202001
  163. A case of primary malignant melanoma of the esophagus with a widely expanded surface area, CLINICAL JOURNAL OF GASTROENTEROLOGY, 12(5), 424-428, 201910
  164. Multicenter study of autoimmune gastritis in Japan: Clinical and endoscopic characteristics, Dig Endosc, 32(3), 364-372, 2020
  165. JAPANESE JOURNAL OF HOSPITAL GENERAL MEDICINE, JAPANESE JOURNAL OF HOSPITAL GENERAL MEDICINE, 16(2), 98-106, 2020
  166. Signet ring cell carcinoma in Helicobacter pylori uninfected mucosa, ENDOSCOPIA DIGESTIVA, 32(1), 83-87, 202001
  167. Characteristics and early diagnosis of gastric cancer discovered after Helicobacter pylori eradication, Gut and Liver, 15(3), 338-345, 2021
  168. The evaluation of esophageal motility using infusion manometry with a trans-nasal endoscope: A preliminary study, Intern Med, 59(7), 887-890, 2020
  169. Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission, BMC Gastroenterol, 20(1), 85, 20200403
  170. Genomic characterization of non-invasive differentiated-type gastric cancer in the Japanese population, Cancers (Basel), 12(2), 510, 202002
  171. Periostin Antisense Oligonucleotide Prevents Hepatic Steatosis and Fibrosis in a Mouse Model of Non-Alcoholic Steatohepatitis, J Gastroenterol Hepatol, 35(12), 2140-2150, 20200504
  172. Two Patients with Paget-Schroetter Syndrome that were Successfully Diagnosed by Doppler Ultrasonography: Case studies with a Literature Review, Intern Med, 59(20), 2623-2627, 20200623
  173. Modifying effect of chronic atrophic gastritis on radiation risk for noncardia gastric cancer according to histological type, Radiat Res, 194(2), 180-187, 20200618
  174. Senescent hepatic stellate cells caused by deoxycholic acid modulates malignant behavior of hepatocellular carcinoma, J Cancer Res Clin Oncol, 146(12), 3255-3268, 2020
  175. Clinical and genomic characteristics of mucosal signet-ring cell carcinoma in Helicobacter pylori-uninfected stomach, BMC Gastroenterol, 20(1), 243, 20200729
  176. A case of Fusobacterium nucleatum infection causing thrombophlebitis of the cavernous sinus diagnosed by lung abscess sampling under video-assisted thoracic surgery, JHGM, 2(5), 120-126, 2020
  177. Granulocyte Colony-stimulating Factor-induced Aortitis with Lung Injury, Splenomegaly, and a Rash During Treatment for Recurrent Extraosseous Mucinous Chondrosarcoma, INTERNAL MEDICINE, 60(8), 1311-1315, 202104
  178. Risk of gastric cancer in the second decade of follow-up after Helicobacter pylori eradication, THE GI FOREFRONT, 16(2), 154-155, 2020
  179. Gastric epithelial neoplasm of fundic-gland mucosa lineage: proposal for a new classification in association with gastric adenocarcinoma of fundic-gland type, JOURNAL OF GASTROENTEROLOGY, 56(9), 814-828, 202109
  180. Immunological and Preventive Effects of Hochuekkito and Kakkonto Against Coronavirus Disease in Healthcare Workers: A Retrospective Observational Study, FRONTIERS IN PHARMACOLOGY, 18(12), 766402, 20211118

Publications such as books

  1. 2020, Helicobacter Vol.24 No.4~No.6, The clinical meaning of the "indefinite for atrophy" lesions within gastric mucosa biopsy specimens in a region with a high prevalence of gastric cancer, The clinical meaning of the "indefinite for atrophy" lesions within gastric mucosa biopsy specimens in a region with a high prevalence of gastric cancer, WILEY, 2020, 10, Scholarly Book, Single work, Masanori Ito, 43, 31-34
  2. 2018, Gastric Cancer, Serum Markers, Springet, 2018, Scholarly Book, Joint work, 978-981-13-1120-8
  3. 2015, 5 Demonstration of the usefulness of epigenetic cancer risk prediction by a multicentre prospective cohort study, 5 Demonstration of the usefulness of epigenetic cancer risk prediction by a multicentre prospective cohort study, 2015, Scholarly Book, Single work
  4. 2015, Rate of unintended Helicobacter pylori eradication in the Vietnamese, Rate of unintended Helicobacter pylori eradication in the Vietnamese, Rate of unintended Helicobacter pylori eradication in the Vietnamese, Rate of unintended Helicobacter pylori eradication in the Vietnamese, 2015, Scholarly Book, Joint work, Hiyama T, Quach DT, Le QD, Ho LX, Vu NH, Shimamoto F, Ito M, Tanaka S, Yoshihara M, Uemura N, Chayama K.
  5. 2015, Time trends in Helicobacter pylori Infection and atrophic gastritis over 40 years in Japan, Time trends in Helicobacter pylori Infection and atrophic gastritis over 40 years in Japan, Time trends in Helicobacter pylori Infection and atrophic gastritis over 40 years in Japan, Helicobacter, 2015, Scholarly Book, Joint work, Kamada T, Haruma K, Ito M, Inoue K, Manabe N, Matsumoto H, Kusunoki H, Hata J, Yoshihara M, Sumii K, Akiyama T, Tanaka S, Shiotani A, David Y. Graham.
  6. 2006/04, Molecular pathologic application as a predictor of lymph node metastasis in submucosal colorectal carcinoma:implication of immunohistochemical alterations at the deepest invasive margin , 2006, 04, Scholarly Book, Joint work, 171

Invited Lecture, Oral Presentation, Poster Presentation

  1. Clinical characteristics and long-term prognosis of gastric neuroendocrine tumors with autoimmune gastritis: retrospective, multicenter study in Japan, Kamada T, Fujisaki J, Sato Y, Chiba T, Kaizaki Y, Ishido K, Ihara Y, Kurihara K, Sugga T, Suzuki H, Ito M, Hirakawa K, Maruyama Y, Gotoda G, Yao T, Haruma K, DDW, 2021/03, Without Invitation, English, DDW, Chicago, USA
  2. Study on endoscopic non-curative resection of early gastric cancer discovered after eradication, Kotachi T, Boda T, Tanaka S, Yorita N, Kiso M, Ninomiya Y, Madina Abuduwaili, Nagasaki N, Oka S, Hiyama T, Ito M, Yoshihara M, Chayama K, The 93rd Annual Meeting of the Japanese Gastric Cancer Association, 2021/03/03, Without Invitation, Japanese, Japanese Gastric Cancer Association, Osaka International Convention Center, Osaka, Japan
  3. Senescent hepatic stellate cells caused by deoxycholic acid modulates malignant behavior of hepatocellular carcinoma., Nguyen PT, Kanno K, Pham QT, Kobayashi T, Miyauchi M, Arihiro K, Tazuma S, Ito M, The 43rd Annual Meeting of the Molecular Biology Society of Japan, 2020/12, Without Invitation, English, The Molecular Biology Society of Japan, Kyoto
  4. Contributions of hepatic stelatte cells into hepatocellular carcinoma, Nguyen PT, Tazuma S, Otani Y, Ito M, The 79th Annual meeting of the Japanese Caner Association, 2020/10/01, Without Invitation, English, the Japanese Cancer Association, Hiroshima, Japan
  5. A study on the use of Long-lasting Insecticidal Nets (LLINs) for Malaria prevention among Indonesian 5-years-old population, Gunara RA, Widawati M, Miyamori D, Kanno K, Ito M, ICPS2020, 2020/10, Without Invitation, English, ICPS, Surabaya, Indonesia
  6. Re-Differentiation of gastric carcinoma after successful Hericobacter Pylori eradication therapy, Urabe Y, Ito M, Tanaka S, Nakamura K, Masuda K, Kotachi T, Boda T, Ono A, Oka S, Hayes CN, Chayama K.Urabe Y, 27th United European Gastroenterology Week (UEGW) 2019, 2019/10/19, Without Invitation, Japanese, Barcelona, Spain
  7. Preceding endoscopic submucosal dissection does not affect for the prognosis of patients with gastric carcinoma with submucosal deep invasion after additional surgery:A propensity score-matched analysis, Kuroki K, Oka S, Tanaka S, Yorita N, Hata K, Kotachi T, Ninomiya Y, Boda T, Ito M, Arihiro K, Chayama K, 27th United European Gastroenterology Week (UEGW) 2019, 2019/10/19, Without Invitation, Japanese, Barcelona, Spain
  8. Long-term effects of Helicobacter pylori eradication in the Asia-Pacific region: Other benefits or concerns? Gastric cancer after H. pylori eradication therapy in Japan, Ito Masanori, The 3rd Joint Session between TDDW - JDDW - KDDW, 2019/09/28, With Invitation, English, The 3rd Joint Session between TDDW - JDDW - KDDW
  9. Re-differentiation of gastric carcinoma after successful Herlicobacter eradication therapy, Urabe Y, Masuda K, Ito M, Ono A, Hayes CN, Nakamura K, Kotachi T, Boda T, Tanaka S, Chayama K, GI Research Academy 2019, 2019/06/28, Without Invitation, Japanese
  10. Autoimmune gastritis in Japan: a study of 200 patients at multicenter study, Terao S, Furuta T, Kamada T, Maruyama Y, Syunto J, Aoki R, Ito M, Manabe N, Sato Y, Oho K, Inoue K, Shiotani A, Haruma K., Terao S, Furuta T, Kamada T, Maruyama Y, Syunto J, Aoki R, Ito M, Manabe N, Sato Y, Oho K, Inoue K, Shiotani A, Haruma K., American Society for Gastrointestinal Endoscopy (ASGE) 2017 (DDW), 2017/05/06, Without Invitation, English, American Society for Gastrointestinal Endoscopy
  11. Evaluation of gastric cancer risk by serum markers, Ito M, Yoshihara M, Tanaka S, Chayama K., Ito M, Yoshihara M, Tanaka S, Chayama K., The 22nd annual meeting of the Japanese Society for Helicobacter Research, 2016/06/24, Without Invitation, English, the Japanese Society for Helicobacter Research
  12. Choline deficiency influences murine colitis via balance of colonic type Ⅰ and Ⅱ NKT cells, Sagami S, Tanaka S, Ueno Y, Fujita A, Nomura M, Nishiyama S, Hayashi R, Urabe Y, Oka S, Ito M, Kitadai Y, Chayama K., Sagami S, Tanaka S, Ueno Y, Fujita A, Nomura M, Nishiyama S, Hayashi R, Urabe Y, Oka S, Ito M, Kitadai Y, Chayama K., American Society for Gastrointestinal Endoscopy (ASGE) 2016 (DDW), 2016/05/21, Without Invitation, English, American Society for Gastrointestinal Endoscopy
  13. Colonic Manifestations of Chronic Granulomatous Disease, Sagami S, Tanaka S, Ueno Y, Nagai K, Fujita A, Nishiyama S, Hayashi R, Oka S, Ito M, Kitadai Y, Miki M, Doi T, Mizoguchi Y, Kobayashi M, Chayama K., Sagami S, Tanaka S, Ueno Y, Nagai K, Fujita A, Nishiyama S, Hayashi R, Oka S, Ito M, Kitadai Y, Miki M, Doi T, Mizoguchi Y, Kobayashi M, Chayama K., American Society for Gastrointestinal Endoscopy (ASGE) 2016 (DDW), 2016/05/21, Without Invitation, English, American Society for Gastrointestinal Endoscopy
  14. Present state of malpractice litigations pertaining to gastroenterological practice in Japan, Hiyama T, Oka S, Ueno Y, Ito M, Kitadai Y, Tanaka S, Yoshihara M, Chayama K, Hiyama T, Oka S, Ueno Y, Ito M, Kitadai Y, Tanaka S, Yoshihara M, Chayama K, Asian Pacific Digestive Week (APDW) 2015, 2015/12/03, Without Invitation, English
  15. Methionine-choline deficient diet relieves dextran sodium sulfate-induced colitis via maintenance of non type Ⅰ NKT cells, Sagami S, Ueno Y, Tanaka S, Nishiyama S, Hayashi R, Nagai K, Oka S, Hiyama T, Ito M, Kitadai Y, Yoshihara M, Chayama K., Sagami S, Ueno Y, Tanaka S, Nishiyama S, Hayashi R, Nagai K, Oka S, Hiyama T, Ito M, Kitadai Y, Yoshihara M, Chayama K., 2015/07/14, Without Invitation, English
  16. The potential role of polysaccharides derived from Ganoderma lucidum fungus mycelia (designated as MAK) on ameliorating indomethacin-induced small intestinal injuries through GM-CSF, Nagai K, Ueno Y, Tanaka S, Sagami S, Nishiyama S, Hayashi R, Shinagawa K, Oka S, Hiyama T, Ito M, Kitadai Y, Yoshihara M, Chayama K, Nagai K, Ueno Y, Tanaka S, Sagami S, Nishiyama S, Hayashi R, Shinagawa K, Oka S, Hiyama T, Ito M, Kitadai Y, Yoshihara M, Chayama K, The 17th International Cogress of Mucosal Immunology (ICMI2015), 2015/07/14, Without Invitation, English
  17. Delayed-release oral mesalazine and probiotics in maintaining of ulcerative colitis-a retrospective cohort study, Sagami S, Ueno Y, Tanaka S, Hayashi R, Nishiyama S, Nagai K, Oka S, Hiyama T, Ito M, Kitadai Y, Yoshihara M, Chayama K, Sagami S, Ueno Y, Tanaka S, Hayashi R, Nishiyama S, Nagai K, Oka S, Hiyama T, Ito M, Kitadai Y, Yoshihara M, Chayama K, The 3rd Annual Meeting of Asian Organization for Crohn's & Colitis (AOCC) 2015, 2015/06/18, Without Invitation, English
  18. he potential role of polysaccharides derived from Ganoderma lucidum fungus mycelia (designated as MAK) on ameliorating indomethacin-induced small intestinal injuries through GM-CSF, Nagai K, Ueno Y, Tanaka S, Sagami S, Nishiyama S, Shinagawa K, Oka S, Yoshida S, Hiyama T, Ito M, Kitadai Y, Yoshihara M, Chayama K, Nagai K, Ueno Y, Tanaka S, Sagami S, Nishiyama S, Shinagawa K, Oka S, Yoshida S, Hiyama T, Ito M, Kitadai Y, Yoshihara M, Chayama K, American Society for Gastrointestinal Endoscopy (ASGE) 2015, 2015/05/16, Without Invitation, English

External Funds

Acceptance Results of Competitive Funds

  1. Practical Research for Innovative Cancer Control, 2015/04/01, 2016/03/31
  2. KAKENHI, Identification of high-risk group for undifferentiated-type gastric cancer and its clinical application for eradication therapy, 2010, 2012
  3. 2006, 2007
  4. KAKENHI, 2016, 2018
  5. Practical Research for Innovative Cancer Control , 2016/04/01, 2017/03/31
  6. Practical Research for Innovative Cancer Control , 2017/04/01, 2018/03/31
  7. 2017, 2017
  8. Practical Research for Innovative Cancer Control , 2018/04/01, 2019/03/31
  9. Practical Research for Innovative Cancer Control , 2019/04/01, 2020/03/31

Social Activities

Other Social Contributions

  1. Scientific Exchange Meeting 2015 in Hiroshima, Certification of PPI safety, Scientific Exchange Meeting 2015 in Hiroshima, Scientific Exchange Meeting 2015 in Hiroshima, 2015/02/26, 2015/02/26, Lecturer, Lecture, General
  2. Scientific Exchange Meeting 2015 in Nagoya/Hiroshima, Kyoto classification of gastritis, Scientific Exchange Meeting 2015 in Nagoya/Hiroshima, Scientific Exchange Meeting 2015 in Nagoya/Hiroshima, 2015/11/05, 2015/11/05, Lecturer, Lecture, Researchesrs

History as Peer Reviews of Academic Papers

  1. 2007, Journal of gastroenterology, Editor
  2. 2008, Journal of gastroenterology, Editor
  3. 2009, Journal of gastroenterology, Editor
  4. 2010, Journal of gastroenterology, Editor
  5. 2011, Journal of gastroenterology, Editor
  6. 2012, Journal of gastroenterology, Editor