Last Updated :2024/04/03

Affiliations, Positions
Hiroshima University, Associate Professor
Web Site
Biophysics/Theoretical Biology/Mathematical Modeling

Basic Information

Academic Degrees

  • Osaka University
  • Osaka University

Research Keywords

  • complex systems
  • mathematical biology
  • biophysics

Educational Activity

Course in Charge

  1. 2024, Liberal Arts Education Program1, 1Term, Seminar in Linear AlgebraI
  2. 2024, Undergraduate Education, 3Term, Introduction to Information Mathematics
  3. 2024, Undergraduate Education, 2Term, Theory of Complex Systems
  4. 2024, Undergraduate Education, 4Term, Mathematics for Modeling and Simulation
  5. 2024, Undergraduate Education, First Semester, Special Study of Mathematics and Informatics for Graduation
  6. 2024, Undergraduate Education, Second Semester, Special Study of Mathematics and Informatics for Graduation
  7. 2024, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Mathematical and Life Sciences
  8. 2024, Graduate Education (Master's Program) , 3Term, Mathematical Modeling C
  9. 2024, Graduate Education (Master's Program) , First Semester, Exercises in Applied Mathematics and Computational Science A
  10. 2024, Graduate Education (Master's Program) , Second Semester, Exercises in Applied Mathematics and Computational Science B
  11. 2024, Graduate Education (Master's Program) , 1Term, Advanced Technologies for Life Science

Research Activities

Academic Papers

  1. Emergence of Bow-tie Architecture in Evolving Feedforward Networks, bioRxiv, 202303
  2. ★, Active Deformable Cells Undergo Cell Shape Transition Associated with Percolation of Topological Defects, arXiv, 202303
  3. Rare-event sampling analysis uncovers the fitness landscape of the genetic code, PLOS Computational Biology, 19(4), e1011034, 202304
  4. A method for morphological feature extraction based on variational auto-encoder : an application to mandible shape, bioRxiv, 20220519
  5. Intercellular exchange of Wnt ligands reduces cell population heterogeneity in embryogenesis, Nature Communications, 14, 202304
  6. Microtopographical guidance of macropinocytic signaling patches, Proceedings of the National Academy of Sciences, 118(50), 20211214
  7. ★, Three-dimensional morphodynamic simulations of macropinocytic cups, iScience, 24(10), 103087-103087, 202110
  8. Comparative mapping of crawling-cell morphodynamics in deep learning-based feature space, PLOS Computational Biology, 17(8), e1009237-e1009237, 20210812
  9. Adaptation of metabolite leakiness leads to symbiotic chemical exchange and to a resilient microbial ecosystem, PLOS Computational Biology, 17(6), 20210623
  10. Advantage of Leakage of Essential Metabolites for Cells, Physical Review Letters, 124(4), 20200128
  11. Embedding dual function into molecular motors through collective motion, SCIENTIFIC REPORTS, 7, 201703
  12. Symbiotic Cell Differentiation and Cooperative Growth in Multicellular Aggregates, PLOS COMPUTATIONAL BIOLOGY, 12(10), 201610
  13. Motif analysis for small-number effects in chemical reaction dynamics, JOURNAL OF CHEMICAL PHYSICS, 145(9), 201609
  14. Theoretical analysis of discreteness-induced transition in autocatalytic reaction dynamics, PHYSICAL REVIEW E, 91(2), 201502
  15. Multicanonical MCMC for sampling rare events: an illustrative review, ANNALS OF THE INSTITUTE OF STATISTICAL MATHEMATICS, 66(3), 611-645, 201406
  16. Evolution of genetic redundancy: the relevance of complexity in genotype-phenotype mapping, NEW JOURNAL OF PHYSICS, 16, 201406
  17. Baldwin effect under multipeaked fitness landscapes: Phenotypic fluctuation accelerates evolutionary rate, PHYSICAL REVIEW E, 87(5), 20130502
  18. Robustness leads close to the edge of chaos in coupled map networks: toward the understanding of biological networks, NEW JOURNAL OF PHYSICS, 15, 201305
  19. Probability of graphs with large spectral gap by multicanonical Monte Carlo, COMPUTER PHYSICS COMMUNICATIONS, 182(1), 223-225, 201101
  20. Multicanonical sampling of rare events in random matrices, PHYSICAL REVIEW E, 82(3), 201009

External Funds

Acceptance Results of Competitive Funds

  1. 2023, 2025
  2. 2021/04/01, 2024/03/31
  3. Grants-in-Aid for Scientific Research Grant-in-Aid for Transformative Research Areas (A), A theoretical study of 3D morphogenesis shaped by tissue-scale cytoskeletal alignment, 2021/09, 2023/03
  4. 2018/04, 2021/03
  5. 2014/04, 2016/03