DAISUKE KAWAHARA
Last Updated :2025/05/09
- Affiliations, Positions
- Hiroshima University Hospital(Division of Clinical Radiology), Associate Professor
- E-mail
- daika99
hiroshima-u.ac.jp
Basic Information
Academic Degrees
- Hiroshima University
- Hiroshima University
In Charge of Primary Major Programs
Research Fields
- Medicine,dentistry, and pharmacy;Boundary medicine;Medical Physics and Radiological Technology
- Informatics;Computing Technologies;Multimedia database
Affiliated Academic Societies
- American Medical Physics Society
- Japanese Society of Medical Physics
- Japanese Society of Radiological Technology
- Japanese Society of Radiation Oncology
Educational Activity
Course in Charge
- 2025, Graduate Education (Master's Program) , First Semester, Seminar on Physics of Nuclear Medicine
- 2025, Graduate Education (Master's Program) , First Semester, English for Scientific Paper
- 2025, Graduate Education (Master's Program) , First Semester, Biostatistics
- 2025, Graduate Education (Master's Program) , Second Semester, Health Physics
- 2025, Graduate Education (Doctoral Program) , First Semester, Clinical Practicum in Medical Physics
- 2025, Graduate Education (Doctoral Program) , Second Semester, Clinical Practicum in Medical Physics
- 2025, Undergraduate Education, Intensive, Practice for medical research
- 2025, Graduate Education (Master's Program) , First Semester, Physics of Diagnostic Radiology
- 2025, Graduate Education (Master's Program) , First Semester, Radiation Oncology Physics
- 2025, Graduate Education (Master's Program) , Second Semester, Physics of Nuclear Medicine
- 2025, Graduate Education (Master's Program) , Second Semester, Seminar on Radiation Oncology Physics
- 2025, Graduate Education (Master's Program) , Second Semester, Seminar on Radiation Dosimetry
- 2025, Graduate Education (Master's Program) , Second Semester, Seminar on Physics of Diagnostic Imaging
Research Activities
Academic Papers
- Radiomics and dosiomics for predicting complete response to definitive chemoradiotherapy patients with oesophageal squamous cell cancer using the hybrid institution model, EUROPEAN RADIOLOGY, 34(2), 1200-1209, 202402
- Unbiased evaluation of predicted gamma passing rate by an event-mixing technique, MEDICAL PHYSICS, 51(1), 5-17, 202401
- Dosiomics for intensity-modulated radiotherapy in patients with prostate cancer: survival analysis stratified by baseline prostate-specific antigen and Gleason grade group in a 2-institutional retrospective study, BRITISH JOURNAL OF RADIOLOGY, 97(1153), 142-149, 20240123
- Usability of synthesized image using generative adversarial network for prediction model of recurrence after radiotherapy in locally advanced cervical cancer, BIOMEDICAL SIGNAL PROCESSING AND CONTROL, 89, 202403
- Artificial intelligence-based diagnosis of the depth of laryngopharyngeal cancer, AURIS NASUS LARYNX, 51(2), 417-424, 202404
- A simulation study on the radiation-induced immune response of tumors after single fraction high-dose irradiation, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 118, 202402
- CT number calibration audit in photon radiation therapy, MEDICAL PHYSICS, 51(3), 1571-1582, 202403
- Predicting the BRAF mutation with pretreatment MRI radiomics features for melanoma brain metastases receiving Gamma Knife radiosurgery, CLINICAL RADIOLOGY, 78(12), E934-E940, 202312
- Novel simulation for dosimetry impact of diaphragm respiratory motion in four-dimensional volumetric modulated arc therapy for esophageal cancer, RADIOTHERAPY AND ONCOLOGY, 187, 202310
- Biological dosimetric impact of dose-delivery time for hypoxic tumour with modified microdosimetric kinetic model, REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY, 28(4), 514-521, 20230801
- Dose uncertainty due to energy dependence in dual-energy computed tomography, POLISH JOURNAL OF RADIOLOGY, 88, e270-e274, 20230607
- A synthesized gamma distribution-based patient-specific VMAT QA using a generative adversarial network, MEDICAL PHYSICS, 50(4), 2488-2498, 202304
- Image masking using convolutional networks improves performance classification of radiation pneumonitis for non-small cell lung cancer, PHYSICAL AND ENGINEERING SCIENCES IN MEDICINE, 46(2), 767-772, 202306
- Prognostic Value of Radiomics Analysis of Skeletal Muscle After Radical Irradiation of Esophageal Cancer, ANTICANCER RESEARCH, 43(4), 1749-1760, 202304
- Image masking using convolutional networks improves performance classification of radiation pneumonitis for non-small cell lung cancer, Physical and Engineering Sciences in Medicine, 46(2), 767-777, 20230101
- MRI image synthesis for fluid-attenuated inversion recovery and diffusion-weighted images with deep learning, Physical and Engineering Sciences in Medicine, 46(1), 313-323, 20230101
- A synthesized gamma distribution-based patient-specific VMAT QA using a generative adversarial network, Medical Physics, 50(4), 2488-2498, 202301
- Physical and biological dosimetric margin according to prescription method for stereotactic body radiation therapy, JOURNAL OF RADIATION RESEARCH, 64(2), 328-334, 20230323
- Influence of different air CT numbers for IVDT on the dose distribution in TomoTherapy MVCT, JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 24(2), 202302
- Tolerance levels of mass density for adaptive helical tomotherapy using MVCT, JOURNAL OF RADIATION RESEARCH, 64(1), 195-201, 20230120
- Predictive gamma passing rate of 3D detector array-based volumetric modulated arc therapy quality assurance for prostate cancer via deep learning, PHYSICAL AND ENGINEERING SCIENCES IN MEDICINE, 45(4), 1073-1081, 202212
- Radiomic Analysis for Pretreatment Prediction of Recurrence Post-Radiotherapy in Cervical Squamous Cell Carcinoma Cancer, DIAGNOSTICS, 12(10), 202210
- Robust optimization of VMAT for prostate cancer accounting for geometric uncertainty, JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 23(9), 202209
- DNA strand breaks based on Monte Carlo simulation in and around the Lipiodol with flattening filter and flattening filter-free photon beams, REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY, 27(3), 392-400, 2022
- Understanding Breast Cancers through Spatial and High-Resolution Visualization Using Imaging Technologies, CANCERS, 14(17), 202209
- Improved biological dosimetric margin model for different PTV margins with stereotactic body radiation therapy in homogeneous and nonhomogeneous tumor regions, Reports of Practical Oncology and Radiotherapy, 202208
- DNA strand breaks based on Monte Carlo simulation in and around the Lipiodol with flattening filter and flattening filter-free photon beams, Reports of Practical Oncology and Radiotherapy, 6, 392-400, 202206
- A prediction model for pathological findings after neoadjuvant chemoradiotherapy for resectable locally advanced esophageal squamous cell carcinoma based on endoscopic images using deep learning, BRITISH JOURNAL OF RADIOLOGY, 95(1135), 2022
- Development of a radiomics and machine learning model for predicting occult cervical lymph node metastasis in patients with tongue cancer, ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 134(1), 93-101, 202207
- Deep learning-based auto segmentation using generative adversarial network on magnetic resonance images obtained for head and neck cancer patients, JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 23(5), 202205
- Stoichiometric CT number calibration using three-parameter fit model for ion therapy, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 99, 22-30, 202207
- Stepwise deep neural network (stepwise-net) for head and neck auto-segmentation on CT images, COMPUTERS IN BIOLOGY AND MEDICINE, 143, 202204
- Availability of Using Diaphragm Matching in Stereotactic Body Radiotherapy (SBRT) at the Time in Breath-holding SBRT for Liver Cancer, Japanese journal of radiological technology, 70(1), 51-56, 201401
- Tolerance levels of mass density for CT number calibration in photon radiation therapy, JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 20(6), 45-52, 201906
- Photon and electron backscatter dose and energy spectrum analysis around Lipiodol using flattened and unflattened beams, JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 20(6), 178-183, 201906
- Availability of applying diaphragm matching with the breath-holding technique in stereotactic body radiation therapy for liver tumors, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 32(4), 557-561, 201606
- Impact of reduction of flux overlap region on kilovoltage cone beam computed tomography image quality and patient's exposure dose, Reports of practical oncology and radiotherapy, 21(5), 460-465, 201609
- Evaluation of beam modeling for small fields using a flattening filter free beam, Radiological Physics and Technology, 10(1), 33-40, 201705
- Marginal prescription equivalent to the isocenter prescription in lung stereotactic body radiotherapy: preliminary study for Japan Clinical Oncology Group trial (JCOG1408), Journal of Radiation Research, 58(1), 149-154, 201701
- ★, Dosimetric impact of Lipiodol in stereotactic body radiation therapy on liver after trans-arterial chemoembolization, Medical physics, 44(1), 342-348, 201701
- Absorbed dose and image quality of Varian TrueBeam CBCT compared with OBI CBCT, Physica Medica, 32(12), 1628-1633, 201612
- Evaluation of Absorbed Dose for CBCT in Image-guided Radiation Therapy: Comparison of Each Devices and Facilities., Japanese Journal of Radiological Technology, 73(4), 309-316, 201704
- Split-VMAT technique to control the expiratory breath-hold time in liver stereotactic body radiation therapy, Physica Medica, 40, 17-23, 201708
- Tolerance levels of CT number to electron density table for photon beam in radiotherapy treatment planning system, Journal of Applied Clinical Medical Physics, 19(1), 271-275, 201801
- Accuracy of the raw-data-based effective atomic numbers and monochromatic CT numbers for contrast medium with a dual-energy CT technique., The British journal of radiology, 91(1082), 201802
- Energy spectrum and dose enhancement due to the depth of the Lipiodol position using flattened and unflattened beams, Reports of Practical Oncology & Radiotherapy, 23(1), 50-56, 201802
- Interfractional diaphragm changes during breath-holding in stereotactic body radiotherapy for liver cancer, Reports of Practical Oncology and Radiotherapy, 23(2), 84-90, 201803
- Effect of secondary electron generation on dose enhancement in Lipiodol with and without a flattening filter, Journal of Applied Clinical Medical Physics, 19(2), 211-217, 201803
- Relative biological effectiveness study of Lipiodol based on microdosimetric-kinetic model, Physica Medica, 46, 89-95, 201802
- Estimation of patient-specific imaging dose for real-time tumor monitoring in lung patients during respiratory-gated radiotherapy., Physics in Medicine & Biology, 63(6), 201803
- A novel verification method using a plastic scintillator imagining system for assessment of gantry sag in radiotherapy, Medical Physics, 45(6), 2411-2424, 201806
- Automatic contrast medium extraction system using electron density data with dual-energy CT, The British journal of radiology, 91(1090), 201810
- Effect of dose-delivery time for flattened and flattening filter-free photon beams based on microdosimetric kinetic model, PLOS ONE, 13(11), 201811
- A novel risk analysis of clinical reference dosimetry based on failure modes and effects analysis, Physica Medcia, 58, 59-65, 201902
- Metal artifact reduction techniques for single energy CT and dual-energy CT with various metal materials, The British Institute of Radiology Open, 201907
- Tolerance levels of mass density for CT number calibration in photon radiation therapy, Journal of Applied Clinical Medical Physics, 20(6), 45-52, 201906
- Evaluation of raw-data-based and calculated electron density for contrast media with a dual-energy CT technique., Reports of Practical Oncology and Radiotherapy, 24(5), 499-506, 201909
- Dosimetric impact of Lipiodol in stereotactic body radiation therapy on liver after trans-arterial chemoembolization, 2018
- Availability of Using Diaphragm Matching in Stereotactic Body Radiotherapy (SBRT) in Breath-Holding SBRT for Liver Cancer, 2016
- Improving automatic contrast agent extraction system using monochromatic CT number, Australasian Physical & Engineering Sciences in Medicine, 42(3), 819-826, 201908
- Evaluation of raw-data-based and calculated electron density for contrast media with a dual-energy CT technique, REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY, 24(5), 499-506, 2019
- Biological dose-enhancement analysis with Monte Carlo simulation for Lipiodol for photon beams, REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY, 24(6), 681-687, 2019
- Predictive gamma passing rate for three-dimensional dose verification with finite detector elements via improved dose uncertainty potential accumulation model, MEDICAL PHYSICS, 47(3), 1349-1356, 202003
- Assessment of biological dosimetric margin for stereotactic body radiation therapy, JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 21(4), 31-41, 202004
- Optimization of irradiation interval for fractionated stereotactic radiosurgery by a cellular automata model with reoxygenation effects, PHYSICS IN MEDICINE AND BIOLOGY, 65(8), 20200421
- Development of a CT number calibration audit phantom in photon radiation therapy: A pilot study, MEDICAL PHYSICS, 47(4), 1509-1522, 202004
- Analysis of cardiac toxicity after definitive chemoradiotherapy for esophageal cancer using a biological dose-volume histogram, JOURNAL OF RADIATION RESEARCH, 61(2), 298-306, 202003
- Evaluation of metal artefact techniques with same contrast scale for different commercially available dual-energy computed tomography scanners, PHYSICAL AND ENGINEERING SCIENCES IN MEDICINE, 43(2), 539-546, 202006
- Dose compensation based on biological effectiveness due to interruption time for photon radiation therapy, BRITISH JOURNAL OF RADIOLOGY, 93(1111), 2020
- A Single Institution's Experience of Definitive Radiotherapy Using Volumetric-modulated Arc Therapy for Hypopharyngeal Cancers, ANTICANCER RESEARCH, 40(7), 4183-4190, 202007
- Synthesized effective atomic numbers for commercially available dual-energy CT, REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY, 25(4), 692-697, 2020
- Long-term outcomes of induction chemotherapy followed by chemoradiotherapy using volumetric-modulated arc therapy as an organ preservation approach in patients with stage IVA-B oropharyngeal or hypopharyngeal cancers, JOURNAL OF RADIATION RESEARCH, 61(4), 554-562, 202007
- Radiobiological effects of the interruption time with Monte Carlo Simulation on multiple fields in photon beams, JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 21(12), 288-294, 202012
- Image synthesis with deep convolutional generative adversarial networks for material decomposition in dual-energy CT from a kilovoltage CT, COMPUTERS IN BIOLOGY AND MEDICINE, 128, 202101
- Evaluation of optimization workflow using custom-made planning through predicted dose distribution for head and neck tumor treatment, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 80, 167-174, 202012
- Predicting the Local Response of Metastatic Brain Tumor to Gamma Knife Radiosurgery by Radiomics With a Machine Learning Method, FRONTIERS IN ONCOLOGY, 10, 20210111
- Formulation of objective indices to quantify machine failure risk analysis for interruptions in radiotherapy, JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 22(1), 165-173, 202101
- Detecting MLC modeling errors using radiomics-based machine learning in patient-specific QA with an EPID for intensity-modulated radiation therapy, MEDICAL PHYSICS, 48(3), 991-1002, 202103
- Image synthesis of monoenergetic CT image in dual-energy CT using kilovoltage CT with deep convolutional generative adversarial networks, JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 22(4), 184-192, 202104
- T1-weighted and T2-weighted MRI image synthesis with convolutional generative adversarial networks, REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY, 26(1), 35-42, 202101
- Efficacy and tolerability of preoperative chemoradiotherapy with S-1 alone for locally advanced rectal cancer, JOURNAL OF RADIATION RESEARCH, 62(2), 300-308, 202103
- Predicting the Local Response of Esophageal Squamous Cell Carcinoma to Neoadjuvant Chemoradiotherapy by Radiomics with a Machine Learning Method Using F-18-FDG PET Images, DIAGNOSTICS, 11(6), 202106
- A prediction model for degree of differentiation for resectable locally advanced esophageal squamous cell carcinoma based on CT images using radiomics and machine-learning, BRITISH JOURNAL OF RADIOLOGY, 94(1124), 2021
- Prediction of radiation pneumonitis after definitive radiotherapy for locally advanced non-small cell lung cancer using multi-region radiomics analysis, SCIENTIFIC REPORTS, 11(1), 20210810
- T1-weighted and T2-weighted MRI image synthesis with convolutional generative adversarial networks, Rep Pract Oncol Radiother, 26(1), 35-42, 20210121
- Efficacy and tolerability of preoperative chemoradiotherapy with S-1 alone for locally advanced rectal cancer, J Radiat Res, 62(2), 300-308, 20210303
- Detecting MLC modeling errors using radiomics-based machine learning in patient-specific QA with an EPID for intensity-modulated radiation therapy, Med Phys, 48(3), 991-1020-991-1020, 202103
- Reduction of margin to compensate the respiratory tumor motion by the analysis of dosimetric internal target volume in lung SBRT with nonuniform volume prescription method., Med Phys, 48(6), 3200-3207, 202106
- Predicting the local response of esophageal squamous cell carcinoma to neoadjuvant chemoradiotherapy by radiomics with a machine learning method using 18F-FDG PET images., 11(6), 1049-1049, 202106
- A prediction model for degree of differentiation for resectable locally advanced esophageal squamous cell carcinoma based on CT images using radiomics and machine-learning, 94(1124), 202108
- Prediction of radiation pneumonitis after definitive radiotherapy for locally advanced non-small cell lung cancer using multi-region radiomics analysis., 10(11), 16, 202108
- Reduction of margin to compensate the respiratory tumor motion by the analysis of dosimetric internal target volume in lung SBRT with nonuniform volume prescription method, MEDICAL PHYSICS, 48(6), 3200-3207, 202106
- Reduction of margin to compensate the respiratory tumor motion by the analysis of dosimetric internal target volume in lung SBRT with nonuniform volume prescription method, MEDICAL PHYSICS, 48(6), 3200-3207, 202106
- Improved cellular automata model shows that indirect apoptotic cell death due to vascular damage enhances the local control of tumors by single fraction high-dose irradiation, BIOMEDICAL PHYSICS & ENGINEERING EXPRESS, 8(1), 202201
- Potential benefits of volumetric modulated arc therapy to reduce the incidence of >= grade 2 radiation pneumonitis in radiotherapy for locally advanced non-small cell lung cancer patients, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 51(12), 1729-1735, 202112
Awards
- 2015/05/25, 15th International Congress of Radiation Research, ICRR, Evaluation of beam modeling for small field using flattening filter free beam
- 2015/05/25, Young Investigation Travel Award (ICRR2015), ICRR
- 2016/11, Hiroshima University President Award, Hiroshima University
- 2018/04/16, 2017 Japan Society of Radiological Technology Awards: Research Encouragement Award and technology Rookie (therapeutic areas), JSRT
External Funds
Acceptance Results of Competitive Funds
- KAKENHI, 2022/04/01, 2025/03/31
- Cloud Funding, 2022/04/01, 2027/03/30
- Varian Research Grant, Biological adaptive radiotherapy (BART) system for treatment interruption for short time or suspension for few days, 2022/06/01, 2024/03/30
- 2021 Research scholarship, 2021/04/01, 2023/03/30
- 2020/04/01, 2021/03/30
- Varian Research Grant, Predicting treatment response for esophagus cancer after radiosurgery from the radiomics analysis, pathological, and blood data by machine learning, 2020/04/01, 2022/03/31
- 2020/04/01, 2024/03/31
- 2020/04/01, 2023/03/31
- 2020/04/01, 2023/03/31
- Prediction model for local control after SRS wtth artificial intelligence
- General assignment B, 2015, 2015
- 2015 Research Grant, Usability of the Lipiodol for SBRT after TACE, 2015, 2015
- General assignment B, Iodine extraction system and create the dose calculation system, 2016, 2016
- 2016 research grants
- 12/5000
Scientific Research Fund (Young Research B), contrast medium extraction system and create the dose calculation system, 2015, 2018
- ICMP2016 Research Achievement Subsidy, 2016, 2016
- General assignment B, 2017, 2017
- 2018 foreign short-term study grants, 2018, 2018
- Research grant, 2018, 2018
- KAKENHI(Grant-in-Aid for Early-Career Scientists), 2020, 2023
Social Activities
History as Committee Members
- Board of Education, Japan Medical Physics Certification Organization (JBMP), 2021/04/01, 2022/03/30
- Member of AI Subcommittee (WG), Future Planning Committee, Japan Society for Radiation Oncology (JASTRO), 2021/04, 2022/03
- JCOG Medical Physics Working Group Member, 2021
- JCOG Medical Physics Working Group Member, 2020/04, 2021/03
- National University Engineers Academic Summit Committee, 2020/04, 2021/03
- Radiology Medical Physics Association Education Course Certification Committee, 2020/04, 2021/03
- Hiroshima Prefectural Radiation Therapy Technology Study Group Multicenter Research Group, 2019/04, 2020/03
- National University Engineers Academic Summit Committee, 2019
- National University Engineers Academic Summit Committee, 2018
Organizing Academic Conferences, etc.
- 2022/11, 2022/11
History as Peer Reviews of Academic Papers
- 2021, Radiation and Oncology, Editor, 1
- 2021, International Journal of Clinical Oncology, Editor, 1
- 2021, Frontier Oncology, Editor, 1
- 2021, Radiological Physics and Technology, Editor, 2
- 2020, Radiological Physics and Technology, Editor, Reviewer, 2
- 2017, Radiological Physics and Technology, Editor, Reviewer, 2
- 2018, Radiological Physics and Technology, Editor, Reviewer, 2