SUSUMU NAKAE

Last Updated :2024/06/06

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Professor
E-mail
snakaehiroshima-u.ac.jp
Self-introduction
Our research focus is the understanding of pathogenesis of acute and chronic inflammatory disorders such as allergy and autoimmunity using gene-modified mice.

Basic Information

Academic Degrees

  • The University of Tokyo
  • The University of Tokyo

Educational Activity

  • [Bachelor Degree Program] School of Applied Biological Science : Department of Applied Biological Science : Molecular Agro-Life Science Program
  • [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Food and AgriLife Science
  • [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Food and AgriLife Science

Research Fields

  • Biological Sciences;Laboratory animal science;Laboratory animal science
  • Medicine,dentistry, and pharmacy;Basic medicine;Immunology
  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Collagenous pathology / Allergology

Research Keywords

  • mast cell
  • Th17 cells
  • Interleukin-33
  • Interleukin-17
  • Mouse models of human diseases
  • allergy
  • Cytokine

Affiliated Academic Societies

  • Collegium Internationale Allergologicum
  • JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE
  • JAPANESE SOCIETY OF ALLERGOLOGY
  • THE JAPANESE SOCIETY FOR IMMUNOLOGY

Educational Activity

Course in Charge

  1. 2024, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  2. 2024, Undergraduate Education, 4Term, Introduction to Molecular Biochemistry
  3. 2024, Undergraduate Education, Second Semester, Graduation Thesis I
  4. 2024, Undergraduate Education, First Semester, Graduation Thesis II
  5. 2024, Undergraduate Education, Second Semester, Graduation Thesis III
  6. 2024, Undergraduate Education, 4Term, Systemic Life Science
  7. 2024, Undergraduate Education, Intensive, Problem Based Learning for Molecular Agro-Life ScienceII
  8. 2024, Undergraduate Education, 4Term, Bio-Analytical Science
  9. 2024, Undergraduate Education, 3Term, Reading of Foreign Literature in Molecular Agro-Life Science
  10. 2024, Undergraduate Education, Intensive, (AIMS)Molecular Agro-life Science
  11. 2024, Undergraduate Education, 3Term, Molecular Agro-life Science
  12. 2024, Graduate Education (Master's Program) , 1Term, Exercises in Food andAgriLife Science A
  13. 2024, Graduate Education (Master's Program) , 2Term, Exercises in Food andAgriLife Science A
  14. 2024, Graduate Education (Master's Program) , 3Term, Exercises in Food andAgriLife Science B
  15. 2024, Graduate Education (Master's Program) , 4Term, Exercises in Food andAgriLife Science B
  16. 2024, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Food andAgriLife Science
  17. 2024, Graduate Education (Master's Program) , 2Term, Applied Molecular Cell Biology I
  18. 2024, Graduate Education (Master's Program) , 4Term, Applied Molecular Cell Biology II
  19. 2024, Graduate Education (Master's Program) , 3Term, Introduction to Disease Models

Research Activities

Academic Papers

  1. Measurement of human skin moisture via high-frequency spectroscopy, Anal Sci, 39(6), 851-856, 202306
  2. Comprehensive Analysis of the Expression and Functions of Pattern Recognition Receptors in Differentiated Cytotrophoblasts Derived from Term Human Placentas, J Immunol, 210(10), 1552-1563, 202305
  3. Laundry detergents and surfactants-induced eosinophilic airway inflammation by increasing IL-33 expression and activating ILC2s, Allergy, 2023
  4. The roles of BST-2 in murine B cell development and on virus propagation, Microbiol Immunol, 67(3), 105-113, 202301
  5. IL-33 deficiency suppresses alveolar bone loss in a ligature-induced periodontitis model, Biomed Res, 44(1), 9-16, 2023
  6. ★, IL-25 contribute to development of chronic contact dermatitis in C57BL/6 mice, but not BALB/c mice., Biochem Biophys Res Commun, 628, 57-63, 20220828
  7. ★, Heterogeneity of Group 2 Innate Lymphoid Cells Defines Their Pleiotropic Roles in Cancer, Obesity, and Cardiovascular Diseases., Front Immunol., 13, 923495, 20220606
  8. Gasdermin D-mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma., Sci Immunol, 7(72), eabl7209, 20220624
  9. Direct platelet adhesion potentiates group 2 innate lymphoid cell functions., Allergy, 77(3), 843-855, 2022
  10. ★, Roles of Mast Cells in Cutaneous Diseases, FRONTIERS IN IMMUNOLOGY, 13, 20220706
  11. Intestinal commensal microbiota and cytokines regulate Fut2(+) Paneth cells for gut defense, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(3), 20220118
  12. Characteristics of tissue-resident ILCs and their potential as therapeutic targets in mucosal and skin inflammatory diseases, ALLERGY, 76(11), 3332-3348, 202111
  13. Innate IL-17A Enhances IL-33-Independent Skin Eosinophilia and IgE Response on Subcutaneous Papain Sensitization, J Invest Dermatol, 141(1), 105-113, 2021
  14. A mouse model of asthma-chronic obstructive pulmonary disease overlap induced by intratracheal papain, Allergy, 76(1), 390-394, 2021
  15. Experimental Mouse Models of Ragweed- and Papain-Induced Allergic Conjunctivitis, Methods Mol Biol, 2223, 133-149, 2021
  16. ★, Interleukin-33 and thymic stromal lymphopoietin, but not interleukin-25, are crucial for development of airway eosinophilia induced by chitin, Sci Rep, 11(1), 5913, 2021
  17. Characteristics of tissue-resident ILCs and their potential as therapeutic targets in mucosal and skin inflammatory diseases, Allergy, 2021
  18. Regulatory T Cells Exhibit Interleukin-33-Dependent Migratory Behavior during Skin Barrier Disruption., Int J Mol Sci, 22(14), 7443, 2021
  19. Direct platelet adhesion potentiates group 2 innate lymphoid cell functions., Allergy, 2021
  20. New insights of human atopic dermatitis provided by mouse models., J Allergy Clin Immunol., 148(3), 722-724, 2021
  21. ★, Critical role of IL-33, but not IL-25 or TSLP, in silica crystal-mediated exacerbation of allergic airway eosinophilia, Biochem Biophys Res Commun, 533(3), 493-500, 2020
  22. Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses., J Clin Invest, 130(7), 3919-3935, 2020
  23. TSLP is a negative regulator of RANKL-induced osteoclastogenesis, Biochem Biophys Res Commun, 530(3), 508-512, 2020
  24. Th2 signals are not essential for the anti-arthritic effects of Trichinella spiralis in mice., Parasite Immunol, 42(1), e12677, 2020
  25. ★, IL-25 exacerbates autoimmune aortitis in IL-1 receptor antagonist-deficient mice., Sci Rep, 9(1), 17067, 2019
  26. Endogenous IL-33 exerts CD8+ T cell antitumor responses overcoming pro-tumor effects by regulatory T cells in a colon carcinoma model., Biochem Biophys Res Commun, 518(2), 331-336, 2019
  27. Innate Lymphoid Cells in the Induction of Obesity, Cell Rep, 28(1), 202-217, 2019
  28. Cyclooxygenase inhibition in mice heightens adaptive- and innate-type responses against inhaled protease allergen and IL-33., Allergy, 74(11), 2237-2240, 2019
  29. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium., Cell, 176(5), 982-997, 2019
  30. Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid., J Allergy Clin Immunol, 143(6), 2190-2201, 2019
  31. The roles of IL-17C in T cell-dependent and -independent inflammatory diseases., Scientific reports, 8(1), 15750-15750, 20181024
  32. IL-36α is involved in hapten-specific T-cell induction, but not local inflammation, during contact hypersensitivity., Biochemical and biophysical research communications, 201810
  33. Interleukin-33 Protects Ischemic Brain Injury by Regulating Specific Microglial Activities, Neuroscience, 385, 75-89, 20180810
  34. Chitin promotes antigen-specific Th2 cell-mediated murine asthma through induction of IL-33-mediated IL-1β production by DCs., Scientific reports, 8(1), 11721-11721, 20180806
  35. Gastrin-Releasing Peptide Is Involved in the Establishment of Allergic Rhinitis in Mice., The Laryngoscope, 201808
  36. Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota., Nature immunology, 19(7), 755-765, 201807
  37. IL-31 is crucial for induction of pruritus, but not inflammation, in contact hypersensitivity., Scientific reports, 8(1), 6639-6639, 20180427
  38. Type 2 innate lymphoid cells disrupt bronchial epithelial barrier integrity by targeting tight junctions through IL-13 in asthmatic patients, Journal of Allergy and Clinical Immunology, 141(1), 300-310.e11, 20180101
  39. The optimal age for epicutaneous sensitization following tape-stripping in BALB/c mice, Allergology International, 67(3), 380-387, 2018
  40. IL-25 enhances TH17 cell–mediated contact dermatitis by promoting IL-1β production by dermal dendritic cells, Journal of Allergy and Clinical Immunology, 2018
  41. IL-33, IL-25 and TSLP contribute to development of fungal-associated protease-induced innate-type airway inflammation., Scientific Reports, 8(1), 18052, 2018
  42. Role of interleukin-25 in development of spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice, Biochemistry and Biophysics Reports, 12, 62-65, 20171201
  43. A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease, SCIENTIFIC REPORTS, 7(1), 12765, 201710
  44. IL-33 in clinical practice: Size matters?, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 140(2), 381-383, 201708
  45. Human eosinophils constitutively express a unique serine protease, PRSS33, ALLERGOLOGY INTERNATIONAL, 66(3), 463-471, 201707
  46. Skin Treatment with Detergent Promotes Protease Allergen-Dependent Epicutaneous Sensitization in a Manner Different from Tape Stripping in Mice, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 137(7), 1578-1582, 201707
  47. Dual genetic absence of STAT6 and IL-10 does not abrogate anti-hyperglycemic effects of Schistosoma mansoni in streptozotocin-treated diabetic mice, EXPERIMENTAL PARASITOLOGY, 177, 1-12, 201706
  48. Disrupting ceramide-CD300f interaction prevents septic peritonitis by stimulating neutrophil recruitment, SCIENTIFIC REPORTS, 7(1), 4298, 201706
  49. A heart-brain-kidney network controls adaptation to cardiac stress through tissue macrophage activation, NATURE MEDICINE, 23(5), 611-+, 201705
  50. Prolonged activation of IL-5-producing ILC2 causes pulmonary arterial hypertrophy., JCI insight, 2(7), e90721, 20170406
  51. Nuclear expression of IL-33 in epidermal keratinocytes promotes wound healing in mice, JOURNAL OF DERMATOLOGICAL SCIENCE, 85(2), 106-114, 201702
  52. Development of chronic allergic responses by dampening Bcl6-mediated suppressor activity in memory T helper 2 cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(5), E741-E750, 201701
  53. Contributions of interleukin-33 and TSLP in a papain-soaked contact lens-induced mouse conjunctival inflammation model, Immunity Inflammation and Disease, 5(4), 515-525, 2017
  54. Involvement of IL-17A-producing TCR γδ T cells in late protective immunity against pulmonary Mycobacterium tuberculosis infection., Immunity, inflammation and disease, 4(4), 401-412, 201612
  55. Platelets constitutively express IL-33 protein and modulate eosinophilic airway inflammation, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 138(5), 1395-+, 201611
  56. TIM-3 is not essential for development of airway inflammation induced by house dust mite antigens, ALLERGOLOGY INTERNATIONAL, 65(4), 459-465, 201610
  57. Regulatory roles of mast cells in immune responses, SEMINARS IN IMMUNOPATHOLOGY, 38(5), 623-629, 201609
  58. TSLP receptor is not essential for house dust mite-induced allergic rhinitis in mice., Biochemistry and biophysics reports, 7, 119-123, 201609
  59. Loss of Dok-1 and Dok-2 in mice causes severe experimental colitis accompanied by reduced expression of IL-17A and IL-22, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 478(1), 135-142, 201609
  60. IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGF beta Release, PLOS ONE, 11(8), e0161507, 201608
  61. Epicutaneous Allergic Sensitization by Cooperation between Allergen Protease Activity and Mechanical Skin Barrier Damage in Mice, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 136(7), 1408-1417, 201607
  62. The Alarmin IL-33 Derived from HSV-2-Infected Keratinocytes Triggers Mast Cell-Mediated Antiviral Innate Immunity, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 136(6), 1290-1292, 201606
  63. Subcutaneous Allergic Sensitization to Protease Allergen Is Dependent on Mast Cells but Not IL-33: Distinct Mechanisms between Subcutaneous and Intranasal Routes, JOURNAL OF IMMUNOLOGY, 196(9), 3559-3569, 201605
  64. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages, NATURE COMMUNICATIONS, 7, 11385, 201605
  65. IL-25, IL-33 and TSLP receptor are not critical for development of experimental murine malaria, Biochemistry and Biophysics Reports, 5, 191-195, 20160301
  66. Promotion of Expansion and Differentiation of Hematopoietic Stem Cells by Interleukin-27 into Myeloid Progenitors to Control Infection in Emergency Myelopoiesis, PLOS PATHOGENS, 12(3), e1005507, 201603
  67. Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(6), E762-E771, 201602
  68. Interleukin-33 enhances programmed oncosis of ST2L-positive low-metastatic cells in the tumour microenvironment of lung cancer, CELL DEATH & DISEASE, 7, e2057, 201601
  69. Interferon-gamma constrains cytokine production of group 2 innate lymphoid cells, IMMUNOLOGY, 147(1), 21-29, 201601
  70. Interleukin-33 in allergic diseases, Japanese Journal of Allergology, 65(10), 1269-1276, 2016
  71. IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function, INFLAMMATORY BOWEL DISEASES, 21(12), 2737-2746, 201512
  72. Roles of Epithelial Cell-Derived Type 2-Initiating Cytokines in Experimental Allergic Conjunctivitis, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56(9), 5194-5202, 201508
  73. IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms, JOURNAL OF CLINICAL INVESTIGATION, 125(7), 2579-2591, 201507
  74. Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in T(H)17 differentiation, NATURE COMMUNICATIONS, 6, 7600, 201507
  75. An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers, IMMUNITY, 43(1), 175-186, 201507
  76. IL-25 and IL-33 Contribute to Development of Eosinophilic Airway Inflammation in Epicutaneously Antigen-Sensitized Mice, PLOS ONE, 10(7), e0134226, 201507
  77. The IL-33/ST2 axis augments effector T-cell responses during acute GVHD, BLOOD, 125(20), 3183-3192, 201505
  78. CCR8 regulates contact hypersensitivity by restricting cutaneous dendritic cell migration to the draining lymph nodes, INTERNATIONAL IMMUNOLOGY, 27(4), 169-181, 201504
  79. The Importance of Bacterial and Viral Infections Associated with Adult Asthma Exacerbations in Clinical Practice, PLOS ONE, 10(4), e0123584, 201504
  80. The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells, NATURE IMMUNOLOGY, 16(3), 276-U239, 201503
  81. IL-33 Is Required for Disposal of Unnecessary Cells during Ovarian Atresia through Regulation of Autophagy and Macrophage Migration, JOURNAL OF IMMUNOLOGY, 194(5), 2140-2147, 201503
  82. Reciprocal effects of Schistosoma mansoni infection on spontaneous autoimmune arthritis in IL-1 receptor antagonist-deficient mice, PARASITOLOGY INTERNATIONAL, 64(1), 13-17, 201502
  83. The Interleukin-33-p38 Kinase Axis Confers Memory T Helper 2 Cell Pathogenicity in the Airway, IMMUNITY, 42(2), 294-308, 201502
  84. Emerging roles of IL-33 in inflammation and immune regulation., Inflammation and Regeneration, 35(2), 69-77, 2015
  85. Potential role of myeloid cell/eosinophil-derived IL-17 in LPS-induced endotoxin shock, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 453(1), 1-6, 201410
  86. Silica and Double-Stranded RNA Synergistically Induce Bronchial Epithelial Apoptosis and Airway Inflammation, AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 51(3), 344-353, 201409
  87. IL-17A as an Inducer for Th2 Immune Responses in Murine Atopic Dermatitis Models, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 134(8), 2122-2130, 201408
  88. Basophil-Derived Interleukin-4 Controls the Function of Natural Helper Cells, a Member of ILC2s, in Lung Inflammation, IMMUNITY, 40(5), 758-771, 201405
  89. Galectin-9 Enhances Cytokine Secretion, but Suppresses Survival and Degranulation, in Human Mast Cell Line, PLOS ONE, 9(1), e86106, 201401
  90. IFN-gamma deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet, AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 305(12), G891-G899, 201312
  91. Screening of novel malaria DNA vaccine candidates using full-length cDNA library, Experimental Parasitology, 135(3), 546-550, 201311
  92. Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes, EMBO MOLECULAR MEDICINE, 5(11), 1720-1739, 201311
  93. GATA-1 regulates the generation and function of basophils, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(46), 18620-18625, 201311
  94. IL-33, but Not IL-25, Is Crucial for the Development of House Dust Mite Antigen-Induced Allergic Rhinitis, PLoS ONE, 8(10), e78099, 20131025
  95. Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6-and IL-10-independent mechanisms, EXPERIMENTAL PARASITOLOGY, 135(2), 388-396, 201310
  96. Mast Cells Play a Key Role in Host Defense against Herpes Simplex Virus Infection through TNF-alpha and IL-6 Production, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 133(9), 2170-2179, 201309
  97. IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation, Journal of Immunology, 190(9), 4489-4499, 20130501
  98. Role of Interleukin-33 in Innate-Type Immune Cells in Allergy, ALLERGOLOGY INTERNATIONAL, 62(1), 13-20, 201303
  99. Dok adaptors play anti-inflammatory roles in pulmonary homeostasis., Genes to cells : devoted to molecular & cellular mechanisms, 18(1), 56-65, 201301
  100. Requirement of apoptosis-inducing kinase 1 for the induction of bronchial asthma following stimulation with ovalbumin., International archives of allergy and immunology, 162(2), 104-114, 2013
  101. Role of IL-25 and IL-33 in allergic diseases, Japanese Journal of Allergology, 62(8), 924-935, 2013
  102. Interleukin-33 in allergy, ALLERGY, 67(10), 1203-1214, 201210
  103. Epithelial Cell-Derived IL-25, but Not Th17 Cell-Derived IL-17 or IL-17F, Is Crucial for Murine Asthma, JOURNAL OF IMMUNOLOGY, 189(7), 3641-3652, 201210
  104. Potential Role of gamma delta T Cell-Derived IL-17 in Acute Cardiac Allograft Rejection, ANNALS OF THORACIC SURGERY, 94(2), 542-548, 201208
  105. Th17 cell-derived IL-17 is dispensable for B cell antibody production, CYTOKINE, 59(1), 108-114, 201207
  106. ST2 Requires Th2-, but Not Th17-, Type Airway Inflammation in Epicutaneously Antigen-Sensitized Mice, ALLERGOLOGY INTERNATIONAL, 61(2), 265-273, 201206
  107. Role of Mast Cells and Basophils in IgE Responses and in Allergic Airway Hyperresponsiveness, JOURNAL OF IMMUNOLOGY, 188(4), 1809-1818, 201202
  108. The Alarmin Interleukin-33 Drives Protective Antiviral CD8(+) T Cell Responses, SCIENCE, 335(6071), 984-989, 201202
  109. Interleukin-17A is involved in enhancement of tumor progression in murine intestine, IMMUNOBIOLOGY, 217(1), 54-60, 201201
  110. Lack of IL-21 signal attenuates graft-versus-leukemia effect in the absence of CD8 T-cells, BONE MARROW TRANSPLANTATION, 46(12), 1557-1565, 201112
  111. Interleukin-16 deficiency suppresses the development of chronic rejection in murine cardiac transplantation model, JOURNAL OF HEART AND LUNG TRANSPLANTATION, 30(12), 1409-1417, 201112
  112. N-acetylglucosaminyltransferase V-deficiency increases susceptibility to murine malaria, EXPERIMENTAL PARASITOLOGY, 129(3), 318-321, 201111
  113. Interleukin-17 Accelerates Allograft Rejection by Suppressing Regulatory T Cell Expansion, CIRCULATION, 124(11), S187-S196, 201109
  114. Requirement of Interaction between Mast Cells and Skin Dendritic Cells to Establish Contact Hypersensitivity, PLOS ONE, 6(9), e25538, 201109
  115. Leptin Enhances Survival and Induces Migration, Degranulation, and Cytokine Synthesis of Human Basophils, JOURNAL OF IMMUNOLOGY, 186(9), 5254-5260, 201105
  116. Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology, JOURNAL OF EXPERIMENTAL MEDICINE, 208(5), 1027-1040, 201105
  117. IL-33 and Airway Inflammation, ALLERGY ASTHMA & IMMUNOLOGY RESEARCH, 3(2), 81-88, 201104
  118. Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation., PloS one, 6(4), e18404, 201104
  119. Functional Specialization of Interleukin-17 Family Members, IMMUNITY, 34(2), 149-162, 201102
  120. Alteration of immune responses by N-acetylglucosaminyltransferase V during allergic airway inflammation, Allergology International, 60(3), 345-354, 2011
  121. Cimetidine enhances antigen-specific IgE and Th2 cytokine production, Allergology International, 60(3), 339-344, 2011
  122. Phosphodiesterase 4B is essential for T(H)2-cell function and development of airway hyperresponsiveness in allergic asthma, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 126(6), 1252-U283, 201012
  123. IL-33 is a crucial amplifier of innate rather than acquired immunity, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(43), 18581-18586, 201010
  124. Altered Effector CD4(+) T Cell Function in IL-21R(-/-) CD4(+) T Cell-Mediated Graft-Versus-Host Disease, JOURNAL OF IMMUNOLOGY, 185(3), 1920-1926, 201008
  125. TNF, but Not IL-6 and IL-17, Is Crucial for the Development of T Cell-Independent Psoriasis-Like Dermatitis in Il1rn(-/-) Mice, JOURNAL OF IMMUNOLOGY, 185(3), 1887-1893, 201008
  126. IL-33-induced activation of human basophils and eosinophils via ST2, Inflammation and Regeneration, 30, 181-185, 201005
  127. The role of recipient mast cells in acute and chronic cardiac allograft rejection in C57BL/6-KitW-sh/W-sh mice, JOURNAL OF HEART AND LUNG TRANSPLANTATION, 29(4), 401-409, 201004
  128. Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung, JOURNAL OF IMMUNOLOGY, 184(8), 4414-4422, 201004
  129. IL-17 Contributes to the Development of Chronic Rejection in a Murine Heart Transplant Model, JOURNAL OF CLINICAL IMMUNOLOGY, 30(2), 235-240, 201003
  130. IL-1 and allergy, Allergology International, 59(2), 125-135, 2010
  131. IL-33 and IL-33 receptors in host defense and diseases, Allergology International, 59(2), 143-160, 2010
  132. Amphiregulin is not essential for ovalbumin-induced acute airway inflammation in mice, Allergology International, 59(2), 207-211, 2010
  133. Amphiregulin is not essential for induction of contact hypersensitivity, Allergology International, 59(3), 277-284, 2010
  134. Development of IL-17-mediated delayed-type hypersensitivity is not affected by down-regulation of IL-25 expression, Allergology International, 59(4), 399-408, 2010
  135. Natural Occurring IL-17 Producing T Cells Regulate the Initial Phase of Neutrophil Mediated Airway Responses, JOURNAL OF IMMUNOLOGY, 183(11), 7523-7530, 200912
  136. Caspase-1, Caspase-8, and Calpain Are Dispensable for IL-33 Release by Macrophages, JOURNAL OF IMMUNOLOGY, 183(12), 7890-7897, 200912
  137. T(H)2 cytokines potently induce an appetite-stimulating peptide, melanin-concentrating hormone, in human vascular endothelial cells, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 124(3), 612-U328, 200909
  138. Therapeutic silencing of an endogenous gene by siRNA cream in an arthritis model mouse, GENE THERAPY, 16(8), 982-989, 200908
  139. Ankylosing enthesitis associated with up-regulated IFN-gamma and IL-17 production in (BXSB x NZB) F-1 male mice: a new mouse model, MODERN RHEUMATOLOGY, 19(3), 316-322, 200906
  140. A protective function for interleukin 17A in T cell-mediated intestinal inflammation, NATURE IMMUNOLOGY, 10(6), 603-U65, 200906
  141. Zinc transporter Znt5/Slc30a5 is required for the mast cell-mediated delayed-type allergic reaction but not the immediate-type reaction, JOURNAL OF EXPERIMENTAL MEDICINE, 206(6), 1351-1364, 200906
  142. Differential Roles of Interleukin-17A and-17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses, IMMUNITY, 30(1), 108-119, 200901
  143. The roles of IL-17A in inflammatory immune responses and host defense against pathogens, IMMUNOLOGICAL REVIEWS, 226, 57-79, 200812
  144. Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils, LABORATORY INVESTIGATION, 88(11), 1245-1253, 200811
  145. An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor., Journal of immunology (Baltimore, Md. : 1950), 181(9), 5981-5989, 200811
  146. IL-17A produced by gammadelta T cells plays a critical role in innate immunity against listeria monocytogenes infection in the liver., Journal of immunology (Baltimore, Md. : 1950), 181(5), 3456-63, 20080901
  147. Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis, JOURNAL OF EXPERIMENTAL MEDICINE, 205(10), 2207-2220, 200809
  148. Role of regulatory and proinflammatory T-cell populations in allergic diseases., The World Allergy Organization journal, 1(1), 9-14, 200801
  149. Mast cells and T-cell expansion., Blood, 111, 2947, 2008
  150. Th17 and allergy, Allergology International, 57(2), 121-134, 2008
  151. IL-33 induces IL-13 production by mouse mast cells independently of IgE-Fc epsilon RI signals, JOURNAL OF LEUKOCYTE BIOLOGY, 82(6), 1481-1490, 200712
  152. TIM-1 and TIM-3 enhancement of Th2 cytokine poduction by mast cells, BLOOD, 110(7), 2565-2568, 200710
  153. IL-33 can promote survival, adhesion and cytokine production in human mast cells, LABORATORY INVESTIGATION, 87(10), 971-978, 200710
  154. Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B, NATURE IMMUNOLOGY, 8(10), 1095-1104, 200710
  155. Mast cell-derived TNF contributes to airway hyperreactivity, inflammation, and T(H)2 cytokine production in an asthma model in mice, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 120(1), 48-55, 200707
  156. Mast cells in the promotion and limitation of chronic inflammation, IMMUNOLOGICAL REVIEWS, 217, 304-328, 200706
  157. Mast cell-derived TNF can promote Th17 cell-dependent neutrophil recruitment in ovalbumin-challenged OTII mice, BLOOD, 109(9), 3640-3648, 200705
  158. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17, JOURNAL OF LEUKOCYTE BIOLOGY, 81(5), 1258-1268, 200705
  159. TNF can contribute to multiple features of ovalbumin-induced allergic inflammation of the airways in mice, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 119(3), 680-686, 200703
  160. IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infection., Journal of immunology (Baltimore, Md. : 1950), 178(6), 3786-3796, 200703
  161. Mast cell-derived tumor necrosis factor can promote nerve fiber elongation in the skin during contact hypersensitivity in mice, AMERICAN JOURNAL OF PATHOLOGY, 169(5), 1713-1721, 200611
  162. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis., Journal of immunology (Baltimore, Md. : 1950), 177(1), 566-573, 200607
  163. IL-1 beta, but not IL-1 alpha, is required for antigen-specific T cell activation and the induction of local inflammation in the delayed-type hypersensitivity responses, INTERNATIONAL IMMUNOLOGY, 18(5), 701-712, 200605
  164. Mast cell-associated TNF promotes dendritic cell migration., Journal of immunology (Baltimore, Md. : 1950), 176(7), 4102-4112, 200604
  165. Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis, INTERNATIONAL IMMUNOLOGY, 18(2), 399-407, 200602
  166. Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF., Journal of immunology (Baltimore, Md. : 1950), 176(4), 2238-2248, 200602
  167. RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(8), 2659-2664, 200602
  168. TNF and IL-17 in the development of excess IL-1 signaling-induced inflammatory diseases in IL-1 receptor antagonist-deficient mice., Ernst Schering Res Found Workshop, 56, 129-153, 2006
  169. Monomeric IgE enhances human mast cell chemokine production: ILA-4 augments and dexamethasone suppresses the response, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 116(6), 1357-1363, 200512
  170. Mast cells enhance T cell activation: Importance of mast cell-derived TNF, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(18), 6467-6472, 200505
  171. Mast cells in the development of adaptive immune responses, NATURE IMMUNOLOGY, 6(2), 135-142, 200502
  172. RabGEF1, a negative regulator of Ras signalling, mast cell activation and skin inflammation., Novartis Foundation symposium, 271, 115-24; discussion 124, 2005
  173. Cardiomyocyte-specific Bcl-2 overexpression attenuates ischemia-reperfusion injury, immune response during acute rejection, and graft coronary artery disease, BLOOD, 104(12), 3789-3796, 200412
  174. TNF-alpha is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice, JOURNAL OF CLINICAL INVESTIGATION, 114(11), 1603-1611, 200412
  175. Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation., Journal of immunology (Baltimore, Md. : 1950), 173(12), 7531-7538, 200412
  176. RabGEF1 is a negative regulator of mast cell activation and skin inflammation, NATURE IMMUNOLOGY, 5(8), 844-852, 200408
  177. Mast cells to the defense, NATURE IMMUNOLOGY, 4(12), 1160-1162, 200312
  178. Impaired selectin-ligand biosynthesis and reduced inflammatory responses in beta-1,4-galactosyltransferdse-I-deficient mice, BLOOD, 102(5), 1678-1685, 200309
  179. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(10), 5986-5990, 200305
  180. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice., Journal of immunology (Baltimore, Md. : 1950), 171(11), 6173-6177, 200312
  181. IL-1 is required for allergen-specific T(h)2 cell activation and the development of airway hypersensitivity response, INTERNATIONAL IMMUNOLOGY, 15(4), 483-490, 200304
  182. IL-1-induced tumor necrosis factor-alpha elicits inflammatory cell infiltration in the skin by inducing IFN-gamma-inducible protein 10 in the elicitation phase of the contact hypersensitivity response, INTERNATIONAL IMMUNOLOGY, 15(2), 251-260, 200302
  183. Antigen-specific T cell Sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses, IMMUNITY, 17(3), 375-387, 200209
  184. Interleukin-1 beta, but not interleukin-1 alpha, is required for T-cell-dependent antibody production, IMMUNOLOGY, 104(4), 402-409, 200112
  185. IL-1 alpha, but not IL-1 beta, is required for contact-allergen-specific T cell activation during the sensitization phase in contact hypersensitivity, INTERNATIONAL IMMUNOLOGY, 13(12), 1471-1478, 200112
  186. IL-1 enhances T cell-dependent antibody production through induction of CD40 ligand and OX40 on T cells, JOURNAL OF IMMUNOLOGY, 167(1), 90-97, 200107
  187. Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice., J Exp Med, 191(2), 313-320, 200001

Publications such as books

  1. 2023/01/20, The Allergy in Practice, Regulation mechanism of ILC2, 2023, 1, J, Tatsukuni Ohno, Susumu Nakae, ISSN 0285-6379
  2. 2022/11/20, The Allergy in Practice, Mechanism of induction of chitin-mediated innate-type airway inflammation, 2022, 11, Joint work, J, Ken Arae, Susumu Nakae, ISSN 0285-6379
  3. 2020/08/25, Clinical Immunology & Allergology, IL-33 in allergy, 2020, 08, Takafumi Numata, Tatsukuni Ohno, Susumu Nakae, ISSN:1881-1930
  4. 2019/10/10, N/A, Th17 cells in immune responses in the skin., 2019, 10, Takafumi Numata, Susumu Nakae, ISBN 978-4-7792-2297-9
  5. 2019/06/10, Experimental Medicine, Role of IL-33, TSLP and IL-25 in allergy., 2019, 06, Tatsukuni Ohno, Takafumi Numata, Susumu Nakae, ISBN 978-4-7581-0379-4
  6. 2018/03/24, Journal of Clinical and Experimental Medicine (IGAKU NO AYUMI), IL-33 as DAMPs., 2018, 03, Tatsukuni Ohno, Susumu Nakae, ISSN: 0039-2359
  7. 2017/12/01, THE LUNG perspectives, IL-33 in airway inflammation., 2017, 12, Ken Arae, Susumu Nakae, ISSN: 0909-5742
  8. 2017/03/20, The Allergy in Practice "Innate immunity in allergic diseases", Interleukin-33 in airway inflammation., 2017, 03, Ken Arae, Hideaki Morita, Kenji Matsumoto, Hirohisa Saito, Susumu Nakae, ISSN: 0285-6379
  9. 2016/07/24, Japanese Journal of Allergology, Interleukin-33 in allergy., 2016, 7, Ken Arae, Hideaki Morita, Kenji Matsumoto, Hirohisa Saito, Susumu Nakae, ISSN: 0021-4884
  10. 2016/07, N/A, IL-33 in mast cells., 2016, 07, Hideaki Morita, Sumika Toyama, Hirohisa Saito, Kenji Matsumoto, Susumu Nakae, ISSN: 1348-7280
  11. 2016/09, N/A, Regulatory role of mast cells in airway inflammation., 2016, 09, Hideaki Morita, Susumu Nakae, Kenji Matsumoto, ISSN: 0386-9806
  12. 2016/07/10, Infection, Inflammation & Immunity, Regulatory role of IL-33-stimulated mast cells in airway inflammation., 2016, 07, Hideaki Morita, Kenji Matsumoto, Susumu Nakae, 0387-1010
  13. 2016/03/25, Clinical immunology & Allergology, Regulatory role of mast cells in airway inflammation., 2016, 03, Hideaki Morita, Susumu Nakae, Kenji Matsumoto, ISSN:1881-1930
  14. 2015/03/21, N/A, IL-33 in allergy., 2015, 03, Hirotoshi Unno, Kenji Matsumoto, Susumu Nakae
  15. 2015/03/21, N/A, IL-33, 2015, 03, Susumu Nakae, ISSN: 0039-2359
  16. 2014, The roles of IL-17A and IL-17F in infection and inflammatory disorders. In Cytokine Frontiers (ed. Y. Yoshimoto & Y. Yoshimoto)., Springer Science + Buisiness Media, LLC, New York, NY, 2014, Scholarly Book, Joint work, Ishigame H, Nakae S
  17. 2014/12/12, The Allergy in Practice "Allergic diseases and biological products", Basic medical pursuit of target molecules., 2014, 12, Maho Suzukawa, Susumu Nakae
  18. 2014/07/01, Respiratory Medical Resaerch, IL-17, 2014, 07, Maho Suzukawa, Susumu Nakae, ISSN: 2187-8560
  19. 2014/04, BIO Clinica "Innate immunity and diseases", DAMPs in allergic diseases., New Science Co., LTD., 2014, 04, Ken Arae, Hirotoshi Unno, Hideaki Morita, Kenji Matsumoto, Susumu Nakae
  20. 2013/10/18, Experimental Medicine, Role of DAMPs in allergic diseases., 2013, 10, Hirotoshi Unno, Hideaki Morita, Ken Arae, Tatsukuni Ohno, Hirohisa Saito, Kenji, Matsumoto, Susumu Nakae, ISBN 978-4-7581-0334-3
  21. 2013/10/18, Experimental Medicine, Eosinophils in chronic allergic diseases., 2013, 10, Hirohisa Saito, Hideaki Morita, Kenji Matsumoto, Susumu Nakae, ISBN 978-4-7581-0334-3
  22. 2013/12/01, Japanese Journal of Allergology, Novel cytokines in allergy, 2013, 12, Hideaki Morita, Hirotoshi Unno, Ken Arae, Tatsukuni Ohno, Hirohisa Saito, Kenji Matsumoto, Susumu Nakae, ISSN: 0021-4884
  23. 2013/03, The Medical Frontline, IL-33 in allergy, 2013, 03, Ken Arae, Hideaki Morita, Tatsukuni Ohno, Kenji Matsumoto, Susumu Nakae, ISSN: 0370-8241
  24. 2013/03/25, Clinical Immunology & Allergology, Mechanism of induction of IL-33 production from macrophages, 2013, 3, Tatsukuni Ohno, Hideaki Morita, Ken Arae, Miyuki Azuma, Susumu Nakae
  25. 2012/09/20, The Allergy in Practice, IL-33 in chronic allergic diseases., 2012, 09, Tatsukuni Ohno, Hideaki Morita, Ken Arae, Kenji Matsumoto, Susumu Nakae, ISSN 0285-6379
  26. 2012/11/20, Experimental Medicine, Role of IL-25 and IL-33 in innate lymphoid cells in infectious and allergic diseases., 2012, 11, Tatsukuni Ohno, Miyuki Azuma, Susumu Nakae, ISBN 978-4-7581-0090-8
  27. 2012/09/03, IgE practice in asthma, IL-33 in allerrgy, 2012, 09, Tatsukuni Ohno, Hideaki Morita, Ken Arae, Kenji Matsumoto, Susumu Nakae
  28. 2012/06/20, Inflammation & Immunity, Role of IL-33 in activation of mast cells and basophils in allergic diseases., 2012, 06, Hideaki Morita, Ken Arae, Tatsukuni Ohno, Kenji Matsumoto, Susumu Nakae, ISSN 0918-8371
  29. 2012/06/25, Clinical Immunology & Allergology, Mast cell activation by IL-33, 2012, 06, Ken Arae, Tatsukuni Ohno, Hideaki Morita, Kenji Matsumoto, Susumu Nakae, ISSN 1881-1930
  30. 2012, JEDCA, IL-17 in contact dermatitis, 2012, Eri Shimura, Susumu Nakae
  31. 2012/06/22, N/A, IL-31 in diseases., Aya Nambu, Susumu Nakae, ISBN_10:4-7809-0132-4
  32. 2012/03/19, Experimental Medicine, IL-33 in chronic allergic inflammation., 2012, 03, Tatsukuni Ohno, Miyuki Azuma, Susumu Nakae, ISBN 978-4-7581-0082-3
  33. 2011/11/10, N/A, Mechanism of Th17 cell-mediated allergic diseases., 2011, 11, Susumu Nakae, ISSN 0287-0185
  34. 2011/09/20, Experimental Medicine, N/A, 2011, 09, Aya Nambu, Susumu Nakae, ISBN 978-4-7581-0076-2
  35. 2011/03/01, Surface Science & Technology avant-grade, Role of IL-17 in the lung and skin., 2011, 03, Susumu Nakae, ISSN 0367-648X
  36. 2011/07/01, KASEAA, IL-17 in diseases., 2011, 07, Aya Nambu, Susumu Nakae, ISSN 0453-073X
  37. 2011/03/20, The Allergy in Practice, IL-17 in contact dermatitis, 2011, 03, Eri Shimura, Susumu Nakae, ISSN 0285-6379
  38. 2010/07/20, Experimental Medicine, Role of IL-33 and IL-33 receptor in development of diseases., 2010, 7, Keisuke Oboki, Tatsukuni Ohno, Naoki Kajiwara, Hirohisa Saito, Susumu Nakae, ISBN 978-4-7581-0308-4
  39. The roles of IL-17A and IL-17F in mucosal infection and allergy. In Th17 cells in health and disease, (ed. S. Jiang), Springer Science + Buisiness Media, LLC, New York, NY, 2011, Scholarly Book, Joint work, Ishigame H, Nakae S, Iwakura Y
  40. 2010, Allergy From the Nose to the Lung, IL-33 in allergy., 2010, Keisuke Oboki, Susumu Nakae, ISBN 978-4-86034-283-8
  41. 2010/03/17, IgE practice in asthma, N/A, 2010, 03, Keisuke Oboki, Hirohisa Saito, Susumu Nakae
  42. 2010/01/25, Clinical Immunology & Allergology, Regulation of immune responses by mast cells., 2010, 01, Keisuke Oboki, Tatsukuni Ohno, Naoki Kajiwara, Hirohisa Saito, Susumu Nakae
  43. 2010/01/05, Infection, Inflammation & Immunity, Th17 cells in inflammation, 2010, 01, Naoki Kajiwara, Keisuke Oboki, Susumu Nakae, ISSN 03871010
  44. 2009/12/04, N/A, IL-33 in allergy, 2009, 12, Keisuke Oboki, Tatsukuni Ohno, Naoki Kajiwara, Hirohisa Saito, Susumu Nakae, ISBN 978-4-7581-0303-9
  45. 2009/12/04, N/A, Th17 cells in allergy, 2009, 12, Naoki Kajiwara, Keisuke Oboki, Tatsukuni Ohno, Hirohisa Saito, Susumu Nakae, ISBN 978-4-7581-0303-9
  46. 2009/07/25, Clinical Immunology & Allergology, Mast cells and Th17 cells in allergy, 2009, 7, Joint work, Naoki Kajiwara, Keisuke Oboki, Tatsukuni Ohno, Hirohisa Saito, Susumu Nakae
  47. 2008/12, Minophagen Medical Review, IL-17 and Th17 cells in immune responses, Minophagen Pharmaceutical Co., LTD., 2008, 12, Tatsukuni Ohno, Keisuke Oboki, Naoki Kajiwara, Hiroshisa Saito, Susumu Nakae
  48. 2008/08/15, SEITAI NO KAGAKU, Role of mast cells in development of Th17 cell-mediated airway inflammation., 2008, 08, Keisuke Oboki, Tatsukuni Ohno, Naoki Kajiwara, Hirohisa Saito, Susumu Nakae, ISSN 0370-9531
  49. 2008/07/26, N/A, IL-17 and Th17 cells in allergic disorders, 2008, 7, Joint work, Keisuke Oboki, Tatsukuni Ohno, Hirohisa Saito, Susumu Nakae
  50. 2007/06/30, Medical Science Digest, Mechanism for allergic airway inflammation by IL-17 and mast cells., 2007, 6, Susumu Nakae, ISSN 1347-4340
  51. 2007/04/25, Clinical Immunology & Allergology, Mechanism for activation of T cells by mast cells, 2007, 4, Susumu Nakae, ISSN 1881-1930
  52. 2004/08/25, Clinical Immunology, Role of IL-17 in development of arthritis, 2004, 8, Single work, Susumu Nakae, ISSN 0386-9695
  53. 2003, The role of IL-1 in the immune system. In Cytokine Knockouts 2nd edition. (ed. G. Fantuzzi), Humana Press (Totowa, NJ), Scholarly Book, Joint work, Nakae S, Horai R, Komiyama Y, Nambu A, Asano M, Nakane A, Iwakura Y
  54. 2003/06, N/A, N/A, 2003, 6, Susumu Nakae
  55. 2002/08/25, Clinical Immunology, N/A, 2002, 8, Joint work, Susumu Nakae, Hiroshi Komiyama, Yoichiro Iwakura, ISSN 0386-9695
  56. 2000/04/25, Clinical Immunology, N/A, 2000, 4, Joint work, Susumu Nakae, Masahide Asano, Reiko Horai, Yoichiro Iwakura, ISSN 0386-9695

Invited Lecture, Oral Presentation, Poster Presentation

  1. Role of the IL-17 family of cytokines in dermatitis Insights from mouse models, Susumu Nakae, The 5th International Conference on Cutaneous Lupus Erythematosus, 2023/05/10, With Invitation, English, The 5th International Conference on Cutaneous Lupus Erythematosus, Tokyo
  2. Analysis of the pathogenic mechanism of asthma-like airway inflammation induced by chitin, an environmental microparticle, Susumu Nakae, Ken Arae, 2020/12/02, Without Invitation, English
  3. Function of Bronchial Epithelial Cells in Asthma, Susumu Nakae, 2018 American Academy of Allergy Asthma & Immunology/World Allergy Organization Joint Congress, 2018/03/05, Without Invitation, English, American Academy of Allergy Asthma & Immunology World Allergy Organization, Orlando, Florida, USA
  4. IL-33 in Innate-Type Airway Inflammation, Susumu Nakae, 18th International Congress of Mucosal Immunology, 2017/07/21, Without Invitation, English, The Society for Mucosal Immunology, Washington DC, USA
  5. IL-33-mediated allergic inflammation, Susumu Nakae, The 23rd East Asia Joint Symposium, the 15th Cross-Strait Symposium on Biomedical Research and the 13th Symposium of the Frontiers of Biomedical Sciences, 2016/10/19, Without Invitation, Japanese
  6. Role of Interleukin-33 in Innate-Type Immune Cells in Allergy, Susumu Nakae, World Allergy Organization Symposium on Immunotherapy & Biologics, 2013/12/14, With Invitation, Japanese, World Allergy Organization, Chicago, USA
  7. IL-33 in inflammation, Susumu Nakae, International Endotoxin and Innate Immunity Society 2012, 2012/10/24, Without Invitation, Japanese, International Endotoxin and Innate Immunity Society, Tokyo
  8. Role of IL-33 in allergy, Susumu Nakae, 29th Symposium of the Collegium Internationale Allergologicum, 2012/10/17, With Invitation, English, Collegium Internationale Allergologicum, Korea
  9. IL-33, Susumu Nakae, XXII World Allergy Congress, 2011/12/04, With Invitation, English, World Allergy Organization, Mexico
  10. IL-33 in allergy, Susumu Nakae, 2011/10/21, Without Invitation, English, Uppsala University, Sweden
  11. IL-17 family cytokines in allergy, Susumu Nakae, 2011/10/20, Without Invitation, English, Karolinska Institute, Sweden
  12. Role of IL-17 in allergic airway inflammation, Susumu Nakae, The 17th East Asia Joint Symposium on Biomedical Research, 2010/06/01, Without Invitation, English, Taiwan

Awards

  1. 2017, Highly Cited Researchers
  2. 2016, Highly Cited Researchers
  3. 2015, Highly Cited Researchers
  4. 2014, Highly Cited Researchers
  5. 2011/06, Phadia Allergy Research Forum Award 2011

External Funds

Acceptance Results of Competitive Funds

  1. 2021/04, 2024/03
  2. Strategic Basic Research Programs(PRESTO), 2020/04/01, 2022/03/31
  3. 2018/04, 2021/03
  4. 2012/03, 2013/04
  5. 2012/04, 2015/03
  6. 2011/10, 2016/03
  7. 2011/04, 2012/03
  8. 2009/04, 2012/03
  9. 2009/04, 2011/03

Social Activities

History as Committee Members

  1. Editorial Board Member, 2019/06, Scientific Reports