NOBUYUKI SAKAYORI
Last Updated :2023/12/04
- Affiliations, Positions
- Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), Associate Professor
- Web Site
- E-mail
- sakayori
hiroshima-u.ac.jp
- Self-introduction
- Investigating the roles of essential fatty acids in brain development and function
Basic Information
Major Professional Backgrounds
- 2020/04/01, 2023/09/30, Hiroshima University, Graduate School of Biomedical and Health Sciences, Assistant Professor
Academic Degrees
Educational Activity
- [Bachelor Degree Program] School of Dentistry : Program of Dentistry : Dentistry
- [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences : Program of Biomedical Science
- [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences : Program of Biomedical Science
- [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Dental Sciences
Research Fields
- Complex systems;Human life science;Eating habits
- Biological Sciences;Neuroscience;Neurophysiology / General neuroscience
- Biology;Biological Science;Developmental biology
- Medicine,dentistry, and pharmacy;Clinical internal medicine;Psychiatric science
Educational Activity
Course in Charge
- 2023, Undergraduate Education, 1Term, Oral Physiology I
- 2023, Undergraduate Education, 2Term, Oral Physiology II
- 2023, Undergraduate Education, 3Term, Practice of Oral Physiology
- 2023, Undergraduate Education, First Semester, Dental Research Practices I
- 2023, Undergraduate Education, Second Semester, Dental Research Practices II
- 2023, Undergraduate Education, First Semester, Dental Research Practices III
- 2023, Undergraduate Education, 4Term, Physiology and Oral Physiology
- 2023, Undergraduate Education, Second Semester, Practice on Basic Dental Sciences
- 2023, Undergraduate Education, 4Term, Physiology and Oral Physiology
- 2023, Graduate Education (Master's Program) , First Semester, Seminar
- 2023, Graduate Education (Master's Program) , Second Semester, Seminar
- 2023, Graduate Education (Master's Program) , First Semester, Research
- 2023, Graduate Education (Master's Program) , Second Semester, Research
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Research
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Research
- 2023, Graduate Education (Master's Program) , First Semester, Physiology and Biological Chemistry
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Physiology and Oral Physiology
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Physiology and Oral Physiology
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Physiology and Oral Physiology
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Physiology and Oral Physiology
- 2023, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
Research Activities
Academic Papers
- Effect of irinotecan administration on amiloride-sensitive sodium taste responses in mice, EUROPEAN JOURNAL OF ORAL SCIENCES, 131(2), 202304
- Characterization of the fatty acid profile in the ventral midbrain of mice exposed to dietary imbalance between omega-6 and omega-3 fatty acids during specific life stages, BMC RESEARCH NOTES, 15(1), 20220905
- The roles of polyunsaturated fatty acids in brain development, Journal of Lipid Nutrition, 31(1), 3-10, 202203
- Maternal dietary imbalance between omega-6 and omega-3 fatty acids triggers the offspring's overeating in mice, Communications Biology, 3, 202008
- Dmrt genes participate in the development of Cajal-Retzius cells derived from the cortical hem in the telencephalon, Developmental Dynamics, 249(6), 698-710, 202006
- Effects of enriched endogenous omega-3 fatty acids on age-related hearing loss in mice, BMC Research Notes, 12, 201911
- Targeting the brain with a neuroprotective omega-3 fatty acid to enhance neurogenesis in hypoxic condition in culture, Molecular Neurobiology, 56(2), 986-999, 201902
- Motor skills mediated through cerebellothalamic tracts projecting to the central lateral nucleus, Molecular Brain, 12, 201902
- The role of essential fatty acids in brain development, Journal of Lipid Nutrition, 27(1), 14-20, 201803
- The role of docosahexaenoic acid in brain development, Journal of the Vitamin Society of Japan, 91(9), 547-554, 201709
- The effect of polyunsaturated fatty acids on neocortical development, The Journal of Japanese Biochemical Society, 89(2), 269-272, 201704
- Mechanisms of DHA transport to the brain and potential therapy to neurodegenerative diseases, Biochimie, 130(11), 163-167, 201611
- Maternal nutritional imbalance between linoleic acid and alpha-linolenic acid increases offspring's anxious behavior with a sex-dependent manner in mice, The Tohoku Journal of Experimental Medicine, 240(1), 31-37, 201609
- Lipids for healthy brain development, Trends in the Sciences, 21(4), 59-62, 201604
- Maternal dietary imbalance between omega-6 and omega-3 polyunsaturated fatty acids impairs neocortical development via epoxy metabolites, Stem Cells, 34(2), 470-482, 201602
- Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells, PLoS One, 9(1), 201401
- Impact of lipid nutrition on neural stem/progenitor cells, Stem Cells International, 201310
- Ninein is essential for the maintenance of the cortical progenitor character by anchoring the centrosome to microtubules, Biology Open, 2(7), 739-749, 201306
- Polyunsaturated fatty acids and their metabolites in neural development and implications for psychiatric disorders, Current Psychopharmacology, 2(1), 73-83, 201303
- Reduced proliferation and excess astrogenesis of Pax6 heterozygous neural stem/progenitor cells, Neuroscience Research, 74(2), 116-121, 201210
- The effects of Fabp7 and Fabp5 on postnatal hippocampal neurogenesis in the mouse, Stem Cells, 30(7), 1532-1543, 201207
- Distinctive effects of arachidonic acid and docosahexaenoic acid on neural stem/progenitor cells, Genes to Cells, 16(7), 778-790, 201107
- The function of fatty acid signals in neurogenesis, Japanese Journal of Neuropsychopharmacology, 31(3), 111-116, 201106
- Neural stem cells for neural development, The Medical Frontline, 64(6), 1259-1273, 200906
Invited Lecture, Oral Presentation, Poster Presentation
- The roles of polyunsaturated fatty acids in brain development, Sakayori N, The 6th Spring Neurodevelopmental Biology Meeting, 2023/04, With Invitation, English
- Ingestive behaviors in mouse offspring are affected by maternal dietary balance of polyunsaturated fatty acids, Sakayori N, 2023/03, Without Invitation, English
- Comprehensive behavioral analyses of male and female mice derived from mothers fed a diet high in omega-6 and low in omega-3 fatty acids, Sakayori N, Fujii K, Katakura M, Takao K, Sugita M, 22nd IUNS International Congress of Nutrition, 2022/12, Without Invitation, English
- Dietary imbalance in polyunsaturated fatty acids during pregnancy affects dopaminergic neurogenesis in their embryos and is associated with offspring's various behavioral abnormalities., Sakayori N, Fujii K, Katakura M, Kobayashi K, Takao K, Sugita M, NEURO2022, 2022/07, Without Invitation, English
- The roles of brain polyunsaturated fatty acids in dopamine-dependent ingestive behaviors, Sakayori N, Katakura M, Sugita M, Kobayashi K, The 44th Annual Meeting of the Japan Neuroscience Society/The 1st CJK International Meeting, 2021/07, Without Invitation, English
- The roles of essential fatty acids in dopaminergic neurogenesis and dopamine-dependent ingestive behaviors, Nobuyuki Sakayori, Kazuto Kobayashi, The 93rd Annual Meeting of the Japanese Biochemical Society, 2020/09, Without Invitation, Japanese
- Lipid molecules to produce willpower and its dysregulation by modern diets, Sakayori N, 2020/09, Without Invitation, English
- The roles of brain essential fatty acids in dopamine-dependent ingestive behaviors., Nobuyuki Sakayori, Kazuto Kobayashi, The 43rd Annual Meeting of the Japan Neuroscience Society, 2020/07, Without Invitation, English
- Maternal dietary imbalance of essential fatty acids induces palatable feeding in the offspring, Sakayori N, The 42nd Annual Meeting of the Molecular Biology Society of Japan, 2019/12, With Invitation, Japanese
- Interdisciplinary research between brain and nutrition, Sakayori N, The 8th Tohoku Brain Science Winter School, 2019/02, With Invitation, Japanese
- Roles of dietary lipids in brain development and function, Sakayori N, The 1st Meeting of the Willdynamics Investigators of Next Generations, 2017/11, With Invitation, Japanese
- Unbalanced n-6/n-3 polyunsaturated fatty acid ratio disturbs neocortical development in mice, Sakayori N, Osumi N, International Conference on Omega-3 and Human Health, 2016/05, With Invitation, English
- Unbalanced n-6/n-3 polyunsaturated fatty acid ratio disturbs neocortical development in mice, Sakayori N, Osumi N, 2014 ELyT Lab Workshop, 2014/02, With Invitation, English
- Function of fatty acid signals in neural stem cells, Sakayori N, Osumi N, The 65th Annual Meeting of the Japan Society for Cell Biology, 2013/06, With Invitation, Japanese
- The effects of fatty acids on neural stem cells, Sakayori N, Osumi N, ELyT School in Sendai – Autumn 2010, 2010/10, With Invitation, English
Awards
- 2022/12/11, 22nd International Congress of Nutrition Young Investigator Excellent Abstract Award, Chair, Organizing Committee of 22nd IUNS-ICN, Chair, Award Selection Committee of 22nd IUNS-ICN, Comprehensive behavioral analyses of male and female mice derived from mothers fed a diet high in omega-6 and low in omega-3 fatty acids
- 2019/09, Best Poster Award, The 28th Annual Meeting of the Japan Society for Lipid Nutrition
- 2018/02, Excellent Poster Presentation Award, The 2nd Meeting of the Willdynamics Investigators of Next Generations
- 2017/02, Best Poster Award, The 6th Tohoku Brain Science Winter School
- 2016/02, Best Research Award, The 5th Tohoku Brain Science Winter School
- 2014/10, Excellent Presentation Award for Young Investigator, The 87th Annual Meeting of the Japanese Biochemical Society
- 2013/02, Excellent Presentation Award, The 2nd Tohoku Brain Science Winter School
- 2012/03, Graduate Student Award for Excellent Research, Tohoku University Graduate School of Medicine
- 2011/09, Sugawara Medicine Promotion Fund Scholarship, Sugawara Medicine Promotion Fund
- 2011/06, Full Exemption from Return of Student Loan by Excellent Achievements, Japan Student Services Organization
- 2010/09, Hasekura Fellowship, Tohoku Neuroscience Global COE "Basic and Translational Research Center for Global Brain Science"
- 2009/08, Hasekura Fellowship, Tohoku Neuroscience Global COE "Basic and Translational Research Center for Global Brain Science"
External Funds
Acceptance Results of Competitive Funds
- KAKENHI(Grant-in-Aid for Scientific Research (B)), 2021/04, 2025/03
- Lotte Research Promotion Grant, 2021/04, 2024/03
- Grant-in-Aid for Young Scientists, 2019/04, 2022/03
- Grant-in-Aid for Scientific Research on Innovative Areas, 2019/04, 2021/03
- Grant-in-Aid for JSPS Fellows, 2017/04, 2020/03
- Grant-in-Aid for Scientific Research on Innovative Areas, 2017/04, 2019/03
- Grant-in-Aid for Young Scientists (B), 2016/04, 2019/03
- Grant for Young Scientists, Japan Society of Nutrition and Food Science, 胎生期における多価不飽和脂肪酸摂取に着目した糖質への依存機構の解明, 2016/04, 2017/03
- Japan Society for Lipid Nutrition, Otsuka Award (Research Grant), 発生期における偏った多価不飽和脂肪酸摂取に伴ううつ病の発症機序の解析, 2015/09, 2016/08
- Scientific Research Promotion Grant, Mishima Kaiun Memorial Foundation, 大脳新皮質形成におけるオメガ3脂肪酸DHAとEPAの異なる役割の解析, 2014/07, 2015/06
- Research Grant for Doctoral Researchers, Institute for International Advanced Research and Education, Tohoku University, 脂肪酸摂取比の乱れが大脳皮質形成および脳機能に及ぼす影響の解析, 2012/07, 2014/03
- Grant-in-Aid for JSPS Fellows, 2012/04, 2015/03
- Research Grant for Starter: Graduate School of Medicine, Tohoku University, 胎生期における脂肪酸摂取比の乱れが大脳皮質形成におよぼす影響の解析, 2011/04, 2012/03
- Research Grant for Master's Researchers, Institute for International Advanced Research and Education, Tohoku University, 神経幹細胞および神経前駆細胞におけるアラキドン酸とドコサヘキサエン酸の効果の解析, 2010/07, 2011/03
Social Activities
History as Committee Members
- Councillor, 2020/01, 2020/03, Japan Society for Lipid Nutrition
- President in Tohoku Area, 2012/03, 2013/03, Society for Young Researchers on Neuroscience
Organizing Academic Conferences, etc.
- 2023/09
- 2023/08
- 2023/03
- 次世代脳プロジェクト冬のシンポジウム2018「意志動力学」「適応回路シフト」若手の会合同シンポジウム, オーガナイザー, 2018/12
- 発生発達基礎医学研究会, 実行委員, 2014/11
- The 2nd Tohoku Brain Science Winter School, 実行副委員長, 2013/02
- Tohoku Brain Science Winter School, 実行委員長, 2012/02