広島大学

Basic Information

Academic Degrees

• Nagasaki University

Research Keywords

• Oral Cancer Medication-Related Osteonecrosis of the Jaw

Educational Activity

Course in Charge

1. 2025, Undergraduate Education, 2Term, Oral Implantology
2. 2025, Undergraduate Education, 1Term, Oral and Maxillofacial Surgery I
3. 2025, Undergraduate Education, 2Term, Oral and Maxillofacial Surgery II
4. 2025, Undergraduate Education, First Semester, Dental Research Practices I
5. 2025, Undergraduate Education, 3Term, Basic Practice of Oral and Maxillofacial Medicine III
6. 2025, Undergraduate Education, 4Term, Basic Practice of Oral and Maxillofacial Medicine IV
7. 2025, Undergraduate Education, Second Semester, Dental Research Practices II
8. 2025, Undergraduate Education, 2Term, Advanced Course in Applied Oral Biology and Medicine
9. 2025, Undergraduate Education, 2Term, Advanced Course in Oral and Maxillofacial Medicine
10. 2025, Undergraduate Education, 2Term, General Seminar on Clinical Dentistry
11. 2025, Undergraduate Education, First Semester, Dental Research Practices III
12. 2025, Undergraduate Education, Year, Clinical Practice (Oral Surgery I)

Research Activities

Academic Papers

1. A retrospective study on odontogenic and non-odontogenic medication-related osteonecrosis of the jaw: Potential differences in clinical features and treatment outcomes, Journal of Dental Sciences, 20(2), 1035-1042, 202412
2. Differences Between Medication-Related Osteonecrosis of the Jaw Caused by Bisphosphonates and Denosumab: Histological, Molecular Biological, and Clinical Studies, Cureus, 202406
3. Medication-related osteonecrosis of the upper jaw involving the zygomatic bone: A case report, International Journal of Surgery Case Reports, 104, 202303
4. Bone resection methods in medication-related osteonecrosis of the jaw in the mandible: An investigation of 206 patients undergoing surgical treatment, Journal of Dental Sciences, 19(3), 1758-1769, 202407
5. Risk factors for the development of medication-related osteonecrosis of the jaw and effects of tooth extraction with local infection, Journal of Dental Sciences, 19(3), 1770-1782, 202307
6. Complete response of recurrent oral squamous cell carcinoma treated with cetuximab in combination with radiotherapy: A case series., Oncology letters, 24(6), 202212
7. Efficacy of 3% hydrogen peroxide solution in cleaning tongue coating before and after surgery: a randomized phase II study, BMC Oral Health, 22(1), 202212
8. Ineffectiveness of Antiresorptive Agent Drug Holidays in Osteoporosis Patients for Treatment of Medication-Related Osteonecrosis of the Jaw: Consideration from Immunohistological Observation of Osteoclast Suppression and Treatment Outcomes, International Journal of Environmental Research and Public Health, 19(17), 202209
9. Surgical treatment and prognosis of posteriorly invading oral cancer: Potential clinical significance of pterygomandibular raphe, Journal of Dental Sciences, 18(1), 81-86, 202207
10. Retrospective Analysis of Treatment Outcomes of Maxillary Sinusitis Associated with Medication-Related Osteonecrosis of the Jaw, International Journal of Environmental Research and Public Health, 19(12), 7430-7430, 202206
    Link to Paper Search Results by DOI
11. Risk factors for developing medication-related osteonecrosis of the jaw when preserving the tooth that can be a source of infection in cancer patients receiving high-dose antiresorptive agents: a retrospective study., Supportive care in cancer, 30(9), 7241-7248, 202205
12. Long-term immunosuppressive therapy for leads to poor outcomes in patients with oral squamous cell carcinoma, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 34(3), 275-279, 202205
13. Relationship between Drug Holidays of Antiresorptive Agents and Surgical Outcomes in Cancer Patients with Medication-Related Osteonecrosis of the Jaw, International Journal of Environmental Research and Public Health, 19(8), 4624-4624, 202204
14. Inhibitory effect of topical antibiotics/antiseptics administration on bacterial growth in the open wound of the jawbone surgery: Randomized controlled, preliminary study., Journal of dental sciences, 16(1), 154-159, 202101
15. Treatment strategies for and outcomes of older patients with oral squamous cell carcinoma., Oral surgery, oral medicine, oral pathology and oral radiology, 129(4), 322-329, 202004
16. Discontinuing oral bisphosphonate therapy during dental extraction does not prevent osteonecrosis of the jaw: A multicenter retrospective study of 341 patients with propensity score matching analysis, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 29(6), 522-526, 201711
17. Clinical Roles of Interleukin-6 and STAT3 in Oral Squamous Cell Carcinoma., Pathology oncology research, 23(2), 425-431, 201704
18. Cetuximab for the treatment of locally advanced and recurrent/metastatic oral cancer: An investigation of distant metastasis., Molecular and clinical oncology, 5(2), 246-252, 201608
19. Regulation and Biological Significance of Formation of Osteoclasts and Foreign Body Giant Cells in an Extraskeletal Implantation Model., Acta histochemica et cytochemica, 49(3), 97-107, 201603
20. Denosumab-associated osteonecrosis of the jaw affects osteoclast formation and differentiation: Pathological features of two cases., Molecular and clinical oncology, 4(2), 191-194, 201602
21. Lipomas of the oral cavity: clinicopathological and immunohistochemical study of 24 cases and review of the literature., Indian journal of otolaryngology and head and neck surgery, 67(Suppl 1), 67-73, 201503
22. ★, Diversity of multinucleated giant cells by microstructures of hydroxyapatite and plasma components in extraskeletal implantation model., Acta biomaterialia, 39, 180-191, 201607
23. Treatment outcomes of adjunctive teriparatide therapy for medication-related osteonecrosis of the jaw (MRONJ): A multicenter retrospective analysis in Japan., Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 25(6), 1079-1083, 202002
24. Relationship between drug holiday of the antiresorptive agents and surgical outcome of medication-related osteonecrosis of the jaw in osteoporosis patients., Scientific reports, 12(1), 11545, 202207
25. Duration of drug holiday of oral bisphosphonate and osteoclast morphology in osteoporosis patients with medication-related osteonecrosis of the jaw, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 34(4), 467-471, 202207

Invited Lecture, Oral Presentation, Poster Presentation

1. Successful treatment outcomes of adjunctive teriparatide therapy in ARONJ patients, Morishita K, Yamada S, Kawakita A, Hayashida S, Tachibana A, Takeuchi N, Uzawa N, Ohbayashi Y, Miyake M, Yoshino A, Sekine J, Yoshiga D, Tominaga K, Narai T, Kodani I, Sasaki N, Shinohara H, Kurita H, 96th IADR, 2018/07, Without Invitation, London, UK

External Funds

Acceptance Results of Competitive Funds

1. 2024/04, 2027/03
2. 2018/04, 2021/03