MITSUHIRO YOSHIDA

Last Updated :2025/04/03

Affiliations, Positions
Hiroshima University Hospital, Associate Professor or Lecturer
E-mail
mh-yoshidahiroshima-u.ac.jp
Self-introduction
My expert is dental anaesthesia and I engaged in chronic orofacial pain research.

Basic Information

Academic Degrees

  • Doctor of Philosophy in Dental Science, Kyushu Dental College

Educational Activity

  • [Bachelor Degree Program] School of Dentistry : Program of Dentistry : Dentistry
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Surgical dentistry

Research Keywords

  • Dental Anesthesiology
  • Oral and Facial Pain

Affiliated Academic Societies

  • Japanese Dental Society of Anesthesiology
    Related URL
  • Japanese Society for Disability and Oral health
  • Japanese Society for Orofacial Pain
  • Japanese Society for Pediatric Dentistry
    Related URL
  • Japanese Association for Study of Pain
  • The Japanese Society for the Study of Chronic Pain
  • International Association for Dental Research
  • Society for Neuroscience

Educational Activity

Course in Charge

  1. 2025, Liberal Arts Education Program1, 2Term, General Health and Oral Sciences I
  2. 2025, Undergraduate Education, 3Term, Dental Anesthesiology
  3. 2025, Undergraduate Education, 4Term, Basic Seminar of Dental Anesthesiology
  4. 2025, Undergraduate Education, First Semester, Dental Research Practices I
  5. 2025, Undergraduate Education, 3Term, Clinical Anatomy for Dentistry I
  6. 2025, Undergraduate Education, 4Term, Clinical Anatomy for Dentistry II
  7. 2025, Undergraduate Education, 3Term, Practice of Clinical Anatomy for Dentistry I
  8. 2025, Undergraduate Education, 4Term, Practice of Clinical Anatomy for Dentistry II
  9. 2025, Undergraduate Education, Second Semester, Dental Research Practices II
  10. 2025, Undergraduate Education, 2Term, General Dentistry III
  11. 2025, Undergraduate Education, 2Term, Basic and Clinical Integrated Theory
  12. 2025, Undergraduate Education, First Semester, Dental Research Practices III
  13. 2025, Undergraduate Education, Academic Year, Clinical Practice (Dental Anesthesiology)
  14. 2025, Undergraduate Education, 4Term, Dental Anesthesiology
  15. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Dental Anesthesiology
  16. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Dental Anesthesiology
  17. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Dental Anesthesiology
  18. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Dental Anesthesiology

Research Activities

Academic Papers

  1. Oral administration of Porphyromonas gingivalis to mice with diet-induced obesity impairs cognitive function associated with microglial activation in the brain, JOURNAL OF ORAL MICROBIOLOGY, 16(1), 20241231
    Link to Paper Search Results by DOI
  2. Dental Suction Interference and Acoustic Respiratory Monitoring, Anesthesia Progress, 71(4), 171-175, 20241204
  3. ★, Anesthetic management of a patient with Sturge-Weber syndrome in sagittal split ramus osteotomy surgery, Clin Case Rep., 12(4), e8747-e8747, 20240407
  4. Severe perioperative lactic acidosis in a pediatric patient with glycogen storage disease type Ia: a case report, JA Clinical Reports, 9(1), 91-95, 20231220
    Link to Paper Search Results by DOI
  5. N-methyl-D-aspartate receptors and glycinergic transmission, respectively, mediate muscle relaxation and immobility of pentobarbital in mice, NEUROSCIENCE LETTERS, 802, 20230401
    Link to Paper Search Results by DOI
  6. Difficult intubation and postoperative aspiration pneumonia associated with Moebius syndrome: a case report, BMC ANESTHESIOLOGY, 22(1), 20221011
    Link to Paper Search Results by DOI
  7. ★, Usefulness of Tranexamic Acid Administration During Sagittal Split Ramus Osteotomy, The Journal of Craniofacial Surgery, 32(1), 273-276, 20210101
  8. The indirect ganma-aminobutyric acid receptor agonist gabaculine-induced loss of the righting reflex may inhibit the descending analgesic pathway, Pharmacology Biochemistry and Behavior, 198, 20200707
  9. NMDA and Purinergic Processes Modulate Neck Muscle Activity Evoked by Noxious Stimulation of Dura, Journal of Oral Pathology & Medicine, 49(6), 547-554, 20200612
  10. Dental 3% Mepivacaine was useful in extracting tooth of a patient with allergy suspicion against additives of local anesthetics, The journal of Hiroshima university dental society, 47(1), 41-44, 20150601
  11. ★, Comparison of Pain Tolerance Thresholds of Upper Limb to Identify the Most Appropriate Venipuncture Site, Journal of Oral and Maxillofacial Surgery, 73(5), 850.e1-850.e5, 20150127
  12. Imipramine ameliorates pain-related negative emotion via induction of brain-derived neurotrophic factor., Cellular and Molecular Neurobiology, 34(8), 1199-1208, 20140826
  13. ★, Anesthetic management of a patient with Sturge-Weber syndrome in sagittal split ramus osteotomy surgery, CLINICAL CASE REPORTS, 12(4), 202404
    Link to Paper Search Results by DOI
  14. Spinal Muscular Atrophy Type III Recognized After Delayed Recovery From Neuromuscular Blockade After an Orthognathic Surgery, JOURNAL OF CRANIOFACIAL SURGERY, 34(6), E580-E582, 202309
    Link to Paper Search Results by DOI
  15. ★, Effective Postoperative Analgesia Using Intravenous Flurbiprofen and Acetaminophen, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 76(9), 1869-1872, 201809
    Link to Paper Search Results by DOI
  16. Endothelin receptor-mediated responses in trigeminal ganglion neurons., J Dent Res., 92(4), 335-339, 201304
  17. Activation of different signals identified with glia cells contribute to the progression of hyperalgesia., Cell Mol Neurobiol., 33(2), 167-174, 201303
  18. Distinct time courses of microglial and astrocytic hyperactivation and the glial contribution to pain hypersensitivity in a facial cancer model., Brain Res., 31, 70-80, 201205
  19. Efficacy and safety of remimazolam besilate for sedation in outpatients undergoing impacted third molar extraction: a prospective exploratory study, BMC Oral Health, 23(1), 2023
  20. Usefulness of new acoustic respiratory sound monitoring with artificial intelligence for upper airway assessment in obese patients during monitored anesthesia care, The Journal of Medical Investigation, 70, 430-435, 2023
  21. ★, Analgesia-based Sedation for Oral Surgery in Patients With Chronic Respiratory Obstructive Disease, JOURNAL OF CRANIOFACIAL SURGERY, 34(1), 2023
    Link to Paper Search Results by DOI
  22. Pentobarbital may protect against neurogenic inflammation after surgery via inhibition of substance P release from peripheral nerves of rats, Neuroscience Letters, 2022
  23. ★, Basic knoeledge for fruid management, Journal of Japanese Dental Society Of Anesthesiology, 49(3), 129-134, 2021
  24. Efficacy of Chest Compressions Performed on Patients in Dental Chairs Versus on the Floor, Anesthesia Progress, 68(2), 85-89, 2021
  25. Effects of intraoperative administration of carbohydrates during long-duration oral and maxillofacial surgery on the metabolism of carbohydrates, proteins, and lipids, ORAL AND MAXILLOFACIAL SURGERY-HEIDELBERG, 19(4), 417-421, 2015
  26. Dura-evoked neck muscle activity involves purinergic and N-methyl-D-aspartate receptor mechanisms, NEUROREPORT, 26(18), 1155-1160, 2015

Invited Lecture, Oral Presentation, Poster Presentation

  1. Consideration of discharge approval criteria after day-case sedation using remimazolam for dental treatment, Aya Oda, Kana Oue, Yoshitaka Shimizu, Tamayo Takahashi, Hisanobu Kamio, Utaka Sasaki, Serika Imamura, Eiji Imado, Mitsuru Doi, Mitsuhiro Yoshida, Hiroshi Hanamoto, 27th international conference of the International Association for Disability and Oral Health, 2024/09/27, Without Invitation, English
  2. Meloxicam prevents carrageenan-induced chronic hyperalgesia by suppressing microglial activation, Mitsuhiro Yoshida, Toru Yamamoto, Eiji Imado, Yatendra Mulpuri, Kana Oue, Shigenobu Kurata, Mitsuru Doi, Yoshitaka Shimizu, Yutaka Tanaka, Naotaka Kishimoto, Hiroshi Hanamoto, Kenji Seo, NEUROSCIENCE2024, 2024/10/08, Without Invitation, English
  3. Correlation of chronic pain related behavior and microglia in trigeminal spinal subnucleus caudalis, Toru Yamamoto, Mitsuhiro Yoshida, Yuhei Koyama, Eiji Imado, Naotaka Kishimoto, Kenji Seo, Oral Neuroscience2023, 2024/04/20, Without Invitation, English
  4. Meloxicam Prevents Carrageenan-induced Chronic Hyperalgesia AndMicroglial Activation, Mitsuhiro Yoshida, Toru Yamamoto, Eiji Imado, Yuhei Koyama, Yatendra Mulpuri, Serika, Imamura, Hisanobu Kamio, Aya Oda, Tamayo Takahashi, Yuzo Imai, Tomoaki Ujita, Emi Sawada, Kana Oue, Naotaka Kishimoto, Kenji Seo, 2024 IADR/AADOCR/CADR General Session & Exhibition, 2024/03/16, Without Invitation, English
  5. Waiting Is Effective for Smoothed ToothExtraction Under Intravenous Sedation, Mitsuhiro Yoshida, Shigehiro Ono, Tamayo Takahashi, Aya Oda, Akari Mukai, Kana Oue, Mitsuru Doi Yoshitaka Shimizu, Masahiro Irifune, 2022 IADR/APR General Session, 2022/06, Without Invitation, English, International association of dental reserch, on line
  6. The Effect Of Tranexamic Acid During Sagittal Split Ramus Osteotomy, M. Yoshida , S. Ono , Y.Shimizu , K. Yoshida , A. Mukai , M. Doi , M. Irifune, IADR/AADR/CADR General Session & Exhibition., 2019/06/20, Without Invitation, English, Vancouver Convention Centre, Canada
  7. The analgesic effect of flurbiprofen in combination with acetaminophen: comparison to that with fentanyl, Mitsuhiro Yoshida, Yoshitaka Shimizu, Keita Yoshida, Akari Mukai, Mitsuru Doi, Masahiro Irifune, International Asociation for Dental Research, 2016/06/24, Without Invitation, English, International Asociation for Dental Research, Seoul, Republic Of Korea