MORIHITO OKADA

Last Updated :2025/06/12

Affiliations, Positions
Research Institute for Radiation Biology and Medicine, Professor
E-mail
morihito1217gmail.com

Basic Information

Academic Degrees

  • Doctor of Philosophy in Medical Science, Kobe University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Respiratory surgery

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, Year, Clinical diagnosis and treatment I
  2. 2025, Undergraduate Education, Year, Systemic Disease Control
  3. 2025, Undergraduate Education, Intensive, Practice for medical research
  4. 2025, Undergraduate Education, Intensive, Practice of Medicine I
  5. 2025, Undergraduate Education, Intensive, Practice of Medicine II
  6. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Surgical Oncology
  7. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Surgical Oncology
  8. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Surgical Oncology
  9. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Surgical Oncology
  10. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Breast Cancer Treatment
  11. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Breast Cancer Treatment
  12. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Surgical Oncology
  13. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Surgical Oncology

Research Activities

Academic Papers

  1. Dual inhibition of GTP-bound KRAS and mTOR in lung adenocarcinoma and squamous cell carcinoma harboring KRAS G12C, CELL COMMUNICATION AND SIGNALING, 23(1), 20250511
  2. Diversity of ER-positive and HER2-negative breast cancer stem cells attained using selective culture techniques, SCIENTIFIC REPORTS, 15(1), 20250310
  3. Segmentectomy versus lobectomy in younger patients with early-stage non-small cell lung cancer, INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY, 40(2), 20250303
  4. Role of guanylate-binding protein 1 in the proliferation of invasive lung adenocarcinoma cells, FRONTIERS IN ONCOLOGY, 15, 20250213
  5. Evaluating the risk of underdiagnosis of invasive breast cancer in needle biopsy-diagnosed ductal carcinoma in situ eligible for radiofrequency ablation, WORLD JOURNAL OF SURGICAL ONCOLOGY, 23(1), 20250205
  6. Exploring the possibility of omitting axillary surgery in patients with clinical node-positive breast cancer achieving ypT0 after neoadjuvant chemotherapy, BREAST CANCER RESEARCH AND TREATMENT, 212(1), 47-56, 202507
  7. Mediastinal lymph node dissection in segmentectomy for peripheral c-stage IA (≤2 cm) non-small-cell lung cancer, J Thorac Cardiovasc Surg, 169(4), 1108-1119.e3, 202504
  8. Comparative oncological features of centrally and peripherally located small-sized radiologically solid-dominant non-small-cell lung cancer, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 67(4), 202504
  9. Role of 18F-fluorodeoxyglucose accumulation in radiological ground-glass opacity of non-small cell lung cancer, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 55(4), 391-398, 202504
  10. CRES3T: A single-arm confirmatory trial of S-1 plus cisplatin with concurrent radical-dose radiotherapy followed by surgery for superior sulcus tumors, LUNG CANCER, 202, 202504
  11. Thoracic and cardiovascular surgeries in Japan during 2022 Annual report by the Japanese Association for Thoracic Surgery, GENERAL THORACIC AND CARDIOVASCULAR SURGERY, 73(4), 254-294, 202504
  12. Risk Factors for Locoregional Relapse After Segmentectomy: Supplementary Analysis of the JCOG0802/WJOG4607L Trial, JOURNAL OF THORACIC ONCOLOGY, 20(2), 157-166, 202502
  13. Feasibility and comparative prognosis of segmentectomy versus lobectomy in centrally located small and solid dominant cN0 non-small cell lung cancer, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 169(2), 202502
  14. Recurrence and prognostic predictors in pathologic T1N0 esophageal squamous cell carcinoma treated with surgery alone, SURGERY, 178, 202502
  15. ASO Author Reflections: Surgical Procedures for Early-Stage Lung Cancer Patients with Low Muscle Mass, Ann Surg Oncol, 32(6), 4191-4192, 202501
  16. Prediction of Pathologic Complete Response in Esophageal Squamous Cell Carcinoma Using Preoperative Serum Small Ribonucleic Acid Obtained After Neoadjuvant Chemoradiotherapy, ANNALS OF SURGICAL ONCOLOGY, 32(1), 570-580, 202501
  17. Omitting Lymph Node Dissection for Small Ground-Glass Opacity-Dominant Tumors, ANNALS OF THORACIC SURGERY, 119(1), 192-198, 202501
  18. Atezolizumab and Platinum Plus Pemetrexed With or Without Bevacizumab for Metastatic Nonsquamous Non-Small Cell Lung Cancer: A Phase 3 Randomized Clinical Trial, JAMA Oncol, 10(3), 315-324, 20240301
  19. Impact of Fusobacterium nucleatum in the treatment of cancer, including radiotherapy and its future potential in esophageal cancer, JOURNAL OF RADIATION RESEARCH, 65, i126-i134, 20241216
  20. Postoperative pulmonary function of patients with lung cancer and interstitial lung abnormalities, GENERAL THORACIC AND CARDIOVASCULAR SURGERY, 72(12), 786-795, 20241201
  21. Factors influencing decision-making between surgery and chemoradiotherapy for esophageal carcinoma from the JCOG0502, FUTURE ONCOLOGY, 20(36), 2849-2854, 20241116
  22. A nomogram to predict the pathological complete response in patients with breast cancer based on the TILs-US score, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 54(9), 967-974, 20240612
  23. Postoperative Lymph Node Recurrence in Esophageal Cancer After Surgery and Prognosis of Chemoradiotherapy, Cancer Diagn Progn, 4(3), 276-280, 20240503
  24. Differences in postoperative prognosis between early-stage lung adenocarcinoma and squamous cell carcinoma, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 54(7), 813-821, 20240427
  25. Effectiveness of pleurodesis for postoperative air leaks after lung resection, JOURNAL OF CARDIOTHORACIC SURGERY, 19(1), 20240102
  26. Diagnostic performance of TILs-US score and LPBC in biopsy specimens for predicting pathological complete response in patients with breast cancer, Int J Clin Oncol, 29(12), 1860-1869, 202412
  27. Mitochondrial Metabolism as a Potential Novel Therapeutic Target for Lung Adenocarcinoma, ANTICANCER RESEARCH, 44(12), 5241-5252, 202412
  28. Reply: Tumor distance from the mediastinum as a preoperative predictor for occult mediastinal nodal metastasis, J Thorac Cardiovasc Surg, 168(5), e138-e139, 202411
  29. Relationship of Immune-Related Adverse Events with Tumor Response and Prognosis in Esophageal Squamous Cell Carcinoma Following Nivolumab Monotherapy, CANCERS, 16(20), 202410
  30. Lymph node dissection in small peripheral lung cancer: Supplemental analysis of JCOG0802/WJOG4607L, J Thorac Cardiovasc Surg, 168(3), 674-683.e1, 202409
  31. Advanced Clinical Trial Chest Surgery Group. Early chest tube removal regardless of drainage volume after anatomic pulmonary resection: A multicenter, randomized, controlled trial, J Thorac Cardiovasc Surg, 168(2), 401-410.e1, 202408
  32. The Role of Emphysema on Postoperative Prognosis in Early-Stage Nonsmall Cell Lung Cancer, ANNALS OF SURGICAL ONCOLOGY, 31(8), 5055-5063, 202408
  33. Sublobar Resection in Early Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor Mutant, ANNALS OF THORACIC SURGERY, 118(2), 395-401, 202408
  34. ASO Author Reflections: How Does Emphysema Contribute to Poor Prognosis After Lung Cancer Surgery?, ANNALS OF SURGICAL ONCOLOGY, 31(7), 4323-4324, 202407
  35. Risk factors for recurrence of esophageal squamous cell carcinoma after pathological complete response to neoadjuvant therapy followed by esophagectomy, WORLD JOURNAL OF SURGERY, 48(7), 1700-1709, 202407
  36. Pathologic Response and Survival after Neoadjuvant Chemotherapy with Bevacizumab Followed by Surgery for Clinical Stage II/IIIA Nonsquamous Non-Small-Cell Lung Cancer: Results from a Phase II Feasibility Study (NAVAL), CANCERS, 16(13), 202407
  37. Clinical Signif icance of Preserving Pulmonary Function After Lung Resection in Early-Stage Non-Small-Cell Lung Cancer, CLINICAL LUNG CANCER, 25(4), 202406
  38. Cross-Correlation of Confocal Images for Excised Breast Tissues of Total Mastectomy, IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 71(5), 1705-1716, 202405
  39. Reply to "Correspondence: SPARC, HEG1, and the Diagnosis of Epithelioid Mesothelioma" by Churg et al, AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 48(5), 632-634, 202405
  40. Risk Factors for Recurrence of Stage I Epidermal Growth Factor Receptor Mutated Lung Adenocarcinoma, ANNALS OF THORACIC SURGERY, 117(4), 202404
  41. Second-line tislelizumab versus chemotherapy in Japanese patients with advanced or metastatic esophageal squamous cell carcinoma: subgroup analysis from RATIONALE-302, ESOPHAGUS, 21(2), 102-110, 202404
  42. Thoracic and cardiovascular surgeries in Japan during 2021Annual report by the Japanese Association for Thoracic Surgery, GENERAL THORACIC AND CARDIOVASCULAR SURGERY, 72(4), 254-291, 202404
  43. Association between prognosis and lymph node status using 18F-fluorodeoxyglucose-positron emission tomography in esophageal squamous cell carcinoma treated with esophagectomy post-neoadjuvant chemotherapy, WORLD JOURNAL OF SURGERY, 48(3), 650-661, 202403
  44. Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer with radiologically pure-solid appearance in Japan (JCOG0802/WJOG4607L): a post-hoc supplemental analysis of a multicentre, open-label, phase 3 trial, LANCET RESPIRATORY MEDICINE, 12(2), 105-116, 202402
  45. Tumor distance from the mediastinum predicts N2 upstaging in clinical stage I lower-lobe non-small cell lung cancer, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 167(2), 202402
  46. NOTCH1 and CREBBP co-mutations negatively affect the benefit of adjuvant therapy in completely resected EGFR-mutated NSCLC: translational research of phase III IMPACT study, MOLECULAR ONCOLOGY, 18(2), 305-316, 202402
  47. Prognostic factors for esophageal squamous cell carcinoma without pathological lymph node metastasis after neoadjuvant therapy and surgery, WORLD JOURNAL OF SURGERY, 48(2), 416-426, 202402
  48. Neoadjuvant nivolumab plus chemotherapy in resectable non-small-cell lung cancer in Japanese patients from CheckMate 816, CANCER SCIENCE, 115(2), 540-554, 202402
  49. SPARC Is a Novel Positive Immunohistochemical Marker of Epithelioid Mesothelioma to Differentiate It From Lung Adenocarcinoma and/or Squamous Cell Carcinoma, AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 48(2), 140-149, 202402
  50. The treatment efficacy and prognosis of each treatment in early postoperative recurrence of esophageal squamous cell carcinoma, SURGERY TODAY, 54(1), 53-63, 202401
  51. Thoracic and cardiovascular surgeries in Japan during 2020: Annual report by the Japanese Association for Thoracic Surgery, GENERAL THORACIC AND CARDIOVASCULAR SURGERY, 72(1), 61-94, 202401
  52. Discrepancy Between Radiological and Pathological Tumor Size in Early-Stage Non-Small Cell Lung Cancer: A Multicenter Study, Semin Thorac Cardiovasc Surg, 36(2), 273-281, 2024
  53. Clinicopathologic study of stage I adenosquamous carcinoma of the lung, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 53(12), 1201-1207, 20231207
  54. A multicenter propensity score-matched analysis of lymphadenectomy in N1-positve lung cancer, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 53(12), 1183-1190, 20231207
  55. Risk factors for loss of pulmonary function after wedge resection for peripheral ground-glass opacity dominant lung cancer, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 64(6), 20231201
  56. Hypoxia-inducible factor 1alpha modulates interstitial pneumonia-mediated lung cancer progression, J Transl Med, 21(1), 857-1892, 20231127
  57. Hypoxia-inducible factor 1ホア modulates interstitial pneumonia-mediated lung cancer progression, JOURNAL OF TRANSLATIONAL MEDICINE, 21(1), 20231127
  58. Lymph node dissection in small peripheral lung cancer: Supplemental analysis of JCOG0802/WJOG4607L, J Thorac Cardiovasc Surg, S0022-5223(23), 01099-1-1892, 20231123
  59. Preoperative predictors for recurrence sites associated with poor post-recurrence survival after surgery of non-small cell lung cancer: a multicenter study, BMC CANCER, 23(1), 20231106
  60. Anatomical segmentectomy versus wedge resection for small (≤2 cm) peripheral non -small cell lung cancer in 80 or more aged elderly patients: a randomized phase Ill study (JCOG2109, AWESOME), JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 53(11), 1077-1081, 20231105
  61. Segmentectomy for cancer control in radiologically pure-solid clinical stage IA3 lung cancer, INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY, 37(3), 20230902
  62. Wedge resection vs. segmentectomy for lung cancer measuring ≤ 2 cm with consolidation tumor ratio > 0.25, FRONTIERS IN ONCOLOGY, 13, 20230828
  63. Reply to Zhou and Yu, Eur J Cardiothorac Surg, 63(6), ezad195-1892, 20230601
  64. Reply to Zhou and Yu, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 63(6), 20230601
  65. FOXA2 Cooperates with Mutant KRAS to Drive Invasive Mucinous Adenocarcinoma of the Lung, CANCER RESEARCH, 83(9), 1443-1458, 20230501
  66. Extracellular vesicle-associated microRNA signatures related to lymphovascular invasion in early-stage lung adenocarcinoma, SCIENTIFIC REPORTS, 13(1), 20230424
  67. Real-world clinical outcomes of nivolumab and taxane as a second- or later-line therapy for recurrent or unresectable advanced esophageal squamous cell carcinoma, FRONTIERS IN ONCOLOGY, 13, 20230417
  68. The efficacy of thoracoscopic surgery for descending necrotizing mediastinitis, INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY, 36(4), 20230403
  69. Extracellular vesicle-associated microRNA signatures related to lymphovascular invasion in early-stage lung adenocarcinoma, SCIENTIFIC REPORTS, 13(1), 20230324
  70. Distribution and prognostic impact of EGFR and KRAS mutations according to histological subtype and tumor invasion status in pTis-3N0M0 lung adenocarcinoma, BMC CANCER, 23(1), 20230314
  71. Reply to Sanz-Santos et al, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 63(3), 20230301
  72. Segmentectomy preserves better immune-nutritional status than lobectomy in patients with early-stage lung cancer, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 63(2), 20230203
  73. Tumour location predicts occult N1 nodal metastasis in clinical stage I non-small-cell lung cancer, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 63(2), 20230203
  74. Wedge resection is an acceptable treatment option for radiologically low-grade lung cancer with solid predominance, INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY, 36(1), 20230109
  75. Lack of Association of Plasma Levels of Soluble Programmed Cell Death Protein 1, Programmed Death-Ligand 1, and CTLA-4 With Survival for Stage II to IIIA NSCLC After Complete Resection and Adjuvant Chemotherapy, JTO CLINICAL AND RESEARCH REPORTS, 4(12), 202312
  76. Musashi-1 Is a Novel Immunohistochemical Marker of Neuroendocrine Carcinoma of the Lung, CANCERS, 15(23), 202312
  77. Asian Perspective on Lung Cancer Screening, THORACIC SURGERY CLINICS, 33(4), 385-400, 202311
  78. Thoracic and cardiovascular surgeries in Japan during 2019 Annual report by the Japanese Association for Thoracic Surgery, GENERAL THORACIC AND CARDIOVASCULAR SURGERY, 71(10), 595-628, 202310
  79. Long-term outcome of patients with peripheral ground-glass opacity-dominant lung cancer after sublobar resections, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 166(4), 1222-+, 202310
  80. Segmentectomy and Wedge Resection Should Be Distinguished as Sublobar Resections for Lung Cancer, Ann Thorac Surg, 116(4), 859, 202310
  81. Risk factors for aortoesophageal fistula in cT4b esophageal squamous cell carcinoma after definitive radiation therapy, JOURNAL OF THORACIC DISEASE, 15(10), 5319-5329, 202310
  82. Early chest tube removal regardless of drainage volume after anatomic pulmonary resection: A multicenter, randomized, controlled trial, Thorac Cardiovasc Surg, S0022-5223(23), 01007-3, 202310
  83. Sublobar Resection for Non-Small Cell Lung Cancer in Octogenarians: A Prospective, Multicenter Study, ANNALS OF THORACIC SURGERY, 116(3), 543-551, 202309
  84. Pembrolizumab plus chemotherapy in Japanese patients with metastatic squamous non-small-cell lung cancer in KEYNOTE-407, CANCER SCIENCE, 114(8), 3330-3341, 202308
  85. Prospective, Multi-Institutional Observational Study of Deterioration in Activities of Daily Living in Elderly Patients After Lung Cancer Surgery, JTO CLINICAL AND RESEARCH REPORTS, 4(8), 202308
  86. The Efficacy of PCSK9 Inhibitors in Treating Hypercholesterolemia Caused by Lorlatinib: A Report of Two Cases., CLINICAL LUNG CANCER, 24(5), e176-e178, 202307
  87. Esophageal Neuroendocrine Carcinoma With Pathological Complete Response After Neoadjuvant Chemotherapy Followed by Robot-assisted Surgery: A Case Report, ANTICANCER RESEARCH, 43(7), 3289-3293, 202307
  88. Segmentectomy for ground-glass-dominant lung cancer with a tumour diameter of 3 cm or less including ground-glass opacity (JCOG1211): a multicentre, single-arm, confirmatory, phase 3 trial, Lancet Respir Med, 11(6), 540-549, 202306
  89. Segmentectomy for ground-glass-dominant lung cancer with a tumour diameter of 3 cm or less including ground- glass opacity (JCOG1211): a multicentre, single-arm, confirmatory, phase 3 trial, LANCET RESPIRATORY MEDICINE, 11(6), 540-549, 202306
  90. Current clinical trials with non-coding RNA-based therapeutics in malignant diseases: A systematic review, TRANSLATIONAL ONCOLOGY, 31, 202305
  91. First-line nivolumab plus ipilimumab or chemotherapy versus chemotherapy alone in advanced esophageal squamous cell carcinoma: a Japanese subgroup analysis of open-label, phase 3 trial (CheckMate 648/ONO-4538-50), ESOPHAGUS, 20(2), 291-301, 202304
  92. Effectiveness of taxanes following nivolumab in patients with advanced esophageal squamous cell carcinoma: a retrospective chart review of patients in ATTRACTION-3, ESOPHAGUS, 20(2), 302-308, 202304
  93. Feasibility of repeated ipsilateral anatomical pulmonary resection, SURGERY TODAY, 53(3), 379-385, 202303
  94. Complications and Survival After Lung Cancer Resection in Interstitial Lung Disease, Ann Thorac Surg, 115(3), 701-708, 202303
  95. Long-term results of chemoradiotherapy with elective nodal irradiation for resectable locally advanced esophageal cancer in three-dimensional planning system, INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 28(3), 382-391, 202303
  96. Usefulness of serum S100A4 and positron-emission tomography on lung cancer accompanied by interstitial pneumonia, THORACIC CANCER, 14(4), 381-388, 202302
  97. Association between Plasminogen Activator Inhibitor-1 and Osimertinib Tolerance in EGFR-Mutated Lung Cancer via Epithelial-Mesenchymal Transition, CANCERS, 15(4), 202302
  98. Impact of oral hygiene on febrile neutropenia during breast cancer chemotherapy, BREAST CANCER, 30(1), 151-155, 202301
  99. [Dawn of Radical Segmentectomy for Small Sized Peripheral Non-small Cell Lung Cancer]., Kyobu Geka, 76(1), 4-8, 202301
  100. 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Predicts Tumor Immune Microenvironment Function in Early Triple-negative Breast Cancer, ANTICANCER RESEARCH, 43(1), 127-136, 202301
  101. Ability of Blood Cell Parameters to Predict Clinical Outcomes of Nivolumab Monotherapy in Advanced Esophageal Squamous Cell Carcinoma, ONCOTARGETS AND THERAPY, 16, 263-273, 2023
  102. Blood biomarkers as predictors of pathological lymph node metastasis in clinical stage T1N0 esophageal squamous cell carcinoma, DISEASES OF THE ESOPHAGUS, 36(1), 20221231
  103. Advanced Clinical Trial Chest Surgery Group (ACTG).S-1 + Cisplatin with Concurrent Radiotherapy Followed by Surgery for Stage IIIA (N2) Lung Squamous Cell Carcinoma: Results of a Phase II Trial, Ann Surg Oncol, 29(13), 8198-8206, 20221229
  104. Discrepancy Between Radiological and Pathological Tumor Size in Early-Stage Non-Small Cell Lung Cancer: A Multicenter Study, Semin Thorac Cardiovasc Surg, S1043-0679(22), 00277-5, 20221210
  105. Impact of the amount of preoperative erector spinae muscle in stage I non-small-cell lung cancer, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 63(1), 20221202
  106. Prevalence of immune-related adverse events and anti-tumor efficacy following immune checkpoint inhibitor therapy in Japanese patients with various solid tumors, BMC CANCER, 22(1), 20221129
  107. First-line nivolumab plus ipilimumab or chemotherapy versus chemotherapy alone in advanced esophageal squamous cell carcinoma: a Japanese subgroup analysis of open-label, phase 3 trial (CheckMate 648/ONO-4538-50), ESOPHAGUS, 20(2), 291-301, 20221119
  108. Phase I Study of Tremelimumab Monotherapy or in Combination With Durvalumab in Japanese Patients With Advanced Solid Tumors or Malignant Mesothelioma, ONCOLOGIST, 27(9), E703-E722, 20220902
  109. The prognostic impact of the ground-glass opacity component in nearly pure-solid stage IA non-small-cell lung cancer, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 62(3), 20220803
  110. Three-Year Follow-Up and Response-Survival Relationship of Nivolumab in Previously Treated Patients with Advanced Esophageal Squamous Cell Carcinoma (ATTRACTION-3), CLINICAL CANCER RESEARCH, 28(15), 20220801
  111. Possible Therapeutic Utility of anti-Cell Adhesion Molecule 1 Antibodies for Malignant Pleural Mesothelioma, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 10, 20220712
  112. Oncological outcome of segmentectomy for early-stage non-small-cell lung cancer with invasive characteristics: a multicentre study, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 62(2), 20220711
  113. Interstitial pneumonia and advanced age negatively influence postoperative pulmonary function, INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, 34(5), 753-759, 20220502
  114. Segmentectomy versus wedge resection for radiological solid predominant and low metabolic non-small cell lung cancer, INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, 34(5), 814-821, 20220502
  115. Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L) : a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial, LANCET, 399(10335), 1607-1617, 20220423
  116. The ratio of CD8+lymphocytes to tumor-infiltrating suppressive FOXP3+effector regulatory T cells is associated with treatment response in invasive breast cancer, DISCOVER ONCOLOGY, 13(1), 20220419
  117. Commentary: Segmentectomy as a standard surgery, a new era in small sized, peripheral, non-small cell lung cancer, JTCVS Tech, 20(12), 210-211, 20220220
  118. Segmentectomy versus lobectomy for solid predominant cN0 lung cancer: analysis using visual evaluation of positron emission tomography, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 61(2), 279-286, 20220124
  119. Malignant prediction of incidental findings using ring-type dedicated breast positron emission tomography, SCIENTIFIC REPORTS, 12(1), 20220121
  120. Randomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA Non-Small-Cell Lung Cancer With EGFR Mutation (IMPACT), JOURNAL OF CLINICAL ONCOLOGY, 40(3), 231-+, 20220120
  121. Randomized, Double-Blind, Phase III Study of Fosnetupitant Versus Fosaprepitant for Prevention of Highly Emetogenic Chemotherapy-Induced Nausea and Vomiting: CONSOLE, JOURNAL OF CLINICAL ONCOLOGY, 40(2), 180-+, 20220110
  122. Risk factors for recurrence of stage I epidermal growth factor receptor mutated lung adenocarcinoma, Ann Thorac Surg, 49(13), 1891-1892, 202212
  123. ASO Visual Abstract: S-1+Cisplatin with Concurrent Radiotherapy Followed by Surgery for Stage IIIA (N2) Lung Squamous Cell Carcinoma: Results of a Phase II Trial, ANNALS OF SURGICAL ONCOLOGY, 29(13), 8209-8210, 202212
  124. Effectiveness of taxanes following nivolumab in patients with advanced esophageal squamous cell carcinoma: a retrospective chart review of patients in ATTRACTION-3, ESOPHAGUS, 202212
  125. Effect of Secondary Prophylactic G-CSF on the Occurrence of Febrile Neutropenia in Breast Cancer, ANTICANCER RESEARCH, 42(12), 5945-5949, 202212
  126. Correlation Between Tumor Uptake on FDG-PET and Malignant Features in Esophageal Squamous Cell Carcinoma After Neoadjuvant Chemotherapy Followed by Surgery, ANTICANCER RESEARCH, 42(12), 6037-6045, 202212
  127. The intersegmental pulmonary vein is not always located on the intersegmental plane of the lung: Evaluation with 3-dimensional volume-rendering image reconstruction, JTCVS TECHNIQUES, 16, 132-138, 202212
  128. Adjuvant atezolizumab in Japanese patients with resected stage IB-IIIA non-small cell lung cancer (IMpower010), CANCER SCIENCE, 113(12), 4327-4338, 202212
  129. Segmentectomy for clinically early-stage primary squamous cell carcinoma of the lung, THORACIC CANCER, 13(24), 3477-3485, 202212
  130. Leukocyte Telomeric G-Tail Length Shortening Is Associated with Esophageal Cancer Recurrence, JOURNAL OF CLINICAL MEDICINE, 11(24), 202212
  131. S-1+Cisplatin with Concurrent Radiotherapy Followed by Surgery for Stage IIIA (N2) Lung Squamous Cell Carcinoma: Results of a Phase II Trial, ANNALS OF SURGICAL ONCOLOGY, 29(13), 8198-8206, 202212
  132. Segmentectomy for Spread Through Air Spaces-positive Lung Adenocarcinoma, Ann Thorac Surg, 114(5), 1989-1990, 202211
  133. The impact of epidermal growth factor receptor mutation status on adjuvant chemotherapy for patients with high-risk stage I lung adenocarcinoma, J Thorac Cardiovasc Surg, 164(5), 1306-1315.e4, 202211
  134. Committee for Scientific Affairs, The Japanese Association for Chest Surgery. The C-reactive protein to albumin ratio is a prognostic factor for stage I non-small cell lung cancer in elderly patients: JACS1303, Surg Today, 52(10), 1463-1471, 202210
  135. The tumor-infiltrating lymphocyte ultrasonography score can provide a diagnostic prediction of lymphocyte-predominant breast cancer preoperatively, JOURNAL OF MEDICAL ULTRASONICS, 49(4), 709-717, 202210
  136. The C-reactive protein to albumin ratio is a prognostic factor for stage I non-small cell lung cancer in elderly patients: JACS1303, SURGERY TODAY, 52(10), 1463-1471, 202210
  137. Dual-phase FDG PET/CT for predicting prognosis in operable breast cancer, BREAST, 65, 98-103, 202210
  138. Randomized phase II trial of pemetrexed-cisplatin plus bevacizumab or thoracic radiotherapy followed by surgery for stage IIIA (N2) nonsquamous non-small cell lung cancer, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 164(3), 661-+, 202209
  139. Prognostic value of quantitative parameters for esophageal squamous cell carcinoma determined by preoperative FDG-PET after trimodal therapy, SURGERY, 172(2), 584-592, 202208
  140. Evaluation of Neoadjuvant Chemoradiotherapy Followed by Surgery for Borderline Resectable Esophageal Squamous Cell Carcinoma, WORLD JOURNAL OF SURGERY, 46(8), 1934-1943, 202208
  141. Psychological states regarding adjuvant chemotherapy in patients with non-small cell lung cancer, Cancer Treat Res Commun, 23(5), 393-401, 202207
  142. A Multicenter Study of Complex Segmentectomy Versus Wedge Resection in Clinical Stage 0-IA Non-Small Cell Lung Cancer, CLINICAL LUNG CANCER, 23(5), 393-401, 202207
  143. Neoadjuvant pemetrexed plus cisplatin followed by pleurectomy for malignant pleural mesothelioma, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 163(6), 1940-+, 202206
  144. Exploratory Analysis Comparing Fosnetupitant Versus Fosaprepitant for Prevention of Highly Emetogenic Chemotherapy-Induced Nausea and Vomiting (CINV): A Randomized, Double-Blind, Phase 3 Study (CONSOLE), ONCOLOGY AND THERAPY, 10(1), 253-262, 202206
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  259. Solid Tumor Size of 2 cm Divides Outcomes of Patients With Mixed Ground Glass Opacity Lung Tumors, ANNALS OF THORACIC SURGERY, 109(5), 1530-1536, 202005
  260. Diagnostic performance of peripheral leukocyte telomere G-tail length for detecting breast cancer, CANCER SCIENCE, 111(5), 1856-1861, 202005
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  316. Bronchoplasties at the Segmental Level, THORACIC SURGERY CLINICS, 28(3), 299-+, 201808
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  342. Clinical Prognosis of Superior Versus Basal Segment Stage I Non-Small Cell Lung Cancer, ANNALS OF THORACIC SURGERY, 104(6), 1896-1901, 201712
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  628. Preoperative nivolumab to evaluate pathological response in patients with stage I non-small cell lung cancer: a study protocol of phase II trial (POTENTIAL)., BMJ Open, 20210317
  629. Breast cancer detection by dedicated breast positron emission tomography according to the World Health Organization classification of breast tumors., Eur J Surg Oncol, 20210303
  630. Surgical challenges in multimodal treatment of N2-stage IIIA non-small cell lung cancer., Jpn J Clin Oncol, 20210303
  631. Appropriate Extent of Lymphadenectomy in Segmentectomy: A Multicenter Study., Jpn J Clin Oncol, 20210303
  632. Bronchial mucosal ablation for bronchial stump closure in right pneumonectomy: a case report., J Med Case Rep, 20210218
  633. Certified thoracic surgeons in Japan: a national database survey on risk-adjusted mortality associated with lung resection., Surg Today, 20210130
  634. Performance of dedicated breast positron emission tomography in the detection of small and low-grade breast cancer., Breast Cancer Res Treat, 20210123
  635. A phase II study of cisplatin plus vinorelbine combined with atezolizumab as adjuvant therapy for completely resected non-small-cell lung cancer with EGFR mutation (West Japan Oncology Group 11719L/ADJUST study)., Ther Adv Med Oncol, 20210121
  636. Salvage surgery for non-small cell lung cancer after tyrosine kinase inhibitor treatment., Lung Cancer, 20210110
  637. Long-term results of definitive chemoradiotherapy for unresectable locally advanced esophageal squamous cell carcinoma., J Radiat Res, 20210101
  638. Recent advances and future perspectives in adjuvant and neoadjuvant immunotherapies for lung cancer., Jpn J Clin Oncol, 20210101
  639. Recent advances and future perspectives in adjuvant and neoadjuvant immunotherapies for lung cancer., Jpn J Clin Oncol, 20210101
  640. Long-term results of definitive chemoradiotherapy for unresectable locally advanced esophageal squamous cell carcinoma., J Radiat Res, 20210101
  641. Clinical Efficacy and Safety of Nivolumab in Japanese Patients With Malignant Pleural Mesothelioma: 3-Year Results of the MERIT Study., JTO Clin Res Rep, 20201229
  642. Prediction of Unexpected N2 Disease Associated With Clinical T1-2N0-1M0 Non-Small-Cell Lung Cancer., Clin Lung Cancer, 20201227
  643. Utility of Newly Proposed Grading System From International Association for the Study of Lung Cancer for Invasive Lung Adenocarcinoma., JTO Clin Res Rep, 20201126
  644. Salvage Surgery for Non-Small Cell Lung Cancer After Definitive Radiotherapy., Ann Thorac Surg, 20201126
  645. Salvage surgery for non-small-cell lung cancer after definitive radiotherapy., Ann Thorac Surg, 20201126
  646. Surgical Procedure Selection for Stage I Lung Cancer: Complex Segmentectomy versus Wedge Resection., Clin Lung Cancer, 20201117
  647. Surgical Procedure Selection for Stage I Lung Cancer: Complex Segmentectomy versus Wedge Resection., Clin Lung Cancer., 20201117
  648. Nivolumab versus chemotherapy in Japanese patients with advanced esophageal squamous cell carcinoma: a subgroup analysis of a multicenter, randomized, open-label, phase 3 trial (ATTRACTION-3)., Esophagus, 20201110
  649. Febrile neutropenia and role of prophylactic granulocyte colony-stimulating factor in docetaxel and cyclophosphamide chemotherapy for breast cancer., Support Care Cancer, 20201104
  650. Segmentectomy vs Lobectomy for Clinical Stage IA Lung Adenocarcinoma With Spread Through Air Spaces., Ann Thorac Surg, 20201102
  651. Comparison of cancer control between segmentectomy and wedge resection in patients with clinical stage IA non-small cell lung cancer., J Thorac Cardiovasc Surg, 20201022
  652. Prediction of Acute Exacerbation of Interstitial Pneumonia Using Visual Evaluation of PET., Ann Thorac Surg, 20201012
  653. ASO Author Reflections: Usefulness of Visual Evaluation of PET in Predicting Prognosis after Lung Resection for Early-Stage Lung Adenocarcinoma and Selecting Candidates for Sublobar Resection., Ann Surg Oncol, 20200923
  654. Patient Selection of Sublobar Resection Using Visual Evaluation of Positron-Emission Tomography (PET) for Early-Stage Lung Adenocarcinoma., Ann Surg Oncol, 20200918
  655. Distribution of Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma After Trimodal Therapy., Ann Surg Oncol, 20200903
  656. Oncologic Outcomes of Complex Segmentectomy: A Multicenter Propensity Score-Matched Analysis., Ann Thorac Surg, 20200812
  657. Commentary: Aspects of epidermal growth factor receptor status: Prognostic factor versus predictive factor., J Thorac Cardiovasc Surg, 20200803
  658. Long-Term Outcomes After Sublobar Resection Versus Lobectomy in Patients With Clinical Stage IA Lung Adenocarcinoma Meeting the Node-Negative Criteria Defined by High-Resolution Computed Tomography and [18F]-Fluoro-2-Deoxy-d-Glucose Positron Emission Tomography., Clin Lung Cancer, 20200619
  659. Novel technique for identification of the pulmonary intersegmental plane using manual jet ventilation during pulmonary segmentectomy., Wideochir Inne Tech Maloinwazyjne, 20200601
  660. Differences in immune response to anesthetics used for day surgery versus hospitalization surgery for breast cancer patients., Clinical and translational medicine, 201709
  661. Outcomes after lobar versus sublobar resection for clinical stage I non-small cell lung cancer in patients with interstitial lung disease., The Journal of thoracic and cardiovascular surgery, 154(3), 1089-1096, 201709
  662. Gene expression profiling of idiopathic interstitial pneumonias (IIPs): identification of potential diagnostic markers and therapeutic targets., BMC medical genetics, 201708
  663. Does the histologic predominance of pathological stage IA lung adenocarcinoma influence the extent of resection?, General thoracic and cardiovascular surgery, 201706

Publications such as books

  1. 2012, Illustrated Anatomical Segmentectomy for Lung Cancer, Nomori,Hiroaki Okada,Morihito

External Funds

Acceptance Results of Competitive Funds

  1. Practical Research for Innovative Cancer Control, 2023//4//1, 2024//3//3
  2. Practical Research for Innovative Cancer Control, 2023//4//1, 2024//3//3
  3. Practical Research for Innovative Cancer Control, 2023//4//1, 2024//3//3
  4. Practical Research for Innovative Cancer Control, 2022//0/4/, 2023//0/3/
  5. Practical Research for Innovative Cancer Control, 2022//0/4/, 2023//0/3/
  6. Practical Research for Innovative Cancer Control, 2022//0/4/, 2023//0/3/
  7. Practical Research for Innovative Cancer Control, 2022//0/4/, 2023//0/3/
  8. Practical Research for Innovative Cancer Control, 2021/04/01, 2022/03/31
  9. Practical Research for Innovative Cancer Control, 2021/04/01, 2022/03/31
  10. Practical Research for Innovative Cancer Control, 2021/04/01, 2022/03/31
  11. Practical Research for Innovative Cancer Control, 2021/04/01, 2022/03/31
  12. Practical Research for Innovative Cancer Control, 2015/04/01, 2016/03/31
  13. KAKENHI, 2014, 2015
  14. KAKENHI, Application of pseudopodia proteomics using excimer laser ablation for investigation of lung cancer invasion, 2012, 2013
  15. KAKENHI, New chemoradiotherapy for esophageal cancer targeting DNA repair proteins, 2010, 2012
  16. KAKENHI, Comprehensive analysis of novel genes regulating the malignant transformation in small-sized lung adenocarcinoma, 2009, 2011
  17. Health and Labour Sciences Research Grants, 2014/05/01, 2015/03/31
  18. KAKENHI, 2013, 2015
  19. KAKENHI, 2013, 2015
  20. KAKENHI, 2012, 2014
  21. KAKENHI, 2012, 2014
  22. KAKENHI, Analysis of tumor hypoxia in lung cancer using real time mass spectrometry, 2010, 2012
  23. KAKENHI, Development of an ultra-sensitive detection of EGFR gene mutations by single-cell level video-mass-scope, 2010, 2011
  24. KAKENHI, 2015, 2018
  25. KAKENHI, 2015, 2018
  26. Practical Research for Innovative Cancer Control , 2016/04/01, 2017/03/31
  27. Practical Research for Innovative Cancer Control , 2017/04/01, 2018/03/31
  28. Practical Research for Innovative Cancer Control , 2017/04/01, 2018/03/31
  29. Practical Research for Innovative Cancer Control , 2018/04/01, 2019/03/31
  30. Practical Research for Innovative Cancer Control , 2018/04/01, 2019/03/31
  31. KAKENHI(Grant-in-Aid for Challenging Research (Exploratory)), 2018, 2019
  32. Practical Research for Innovative Cancer Control , 2019/04/01, 2020/03/31
  33. Practical Research for Innovative Cancer Control , 2019/04/01, 2020/03/31
  34. Practical Research for Innovative Cancer Control, 2020/04/01, 2021/03/31
  35. Practical Research for Innovative Cancer Control, 2020/04/01, 2021/03/31
  36. Practical Research for Innovative Cancer Control, 2020/04/01, 2021/03/31
  37. Practical Research for Innovative Cancer Control, 2020/04/01, 2021/03/31

Social Activities

History as Peer Reviews of Academic Papers

  1. Journal of Clinical Oncology
  2. Journal of Thoracic and Cardiovascular Surgery
  3. Chest
  4. Annals of Thoracic Surgery
  5. European Journal of Cardiothoracic Surgery
  6. Lung Cancer
  7. Journal of Thoracic Oncology
  8. Surgery Today
  9. Cancer Science
  10. Japanese Journal of Clinical Oncology, Editor
  11. General Thoracic and Cardiovascular Surgery, Editor