広島大学

Basic Information

Academic Degrees

• Hiroshima University

Educational Activity

• [Bachelor Degree Program] School of Dentistry : Program of Dentistry : Dentistry
• [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
• [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Dental Sciences

Research Fields

• Medicine,dentistry, and pharmacy;Dentistry;Prosthodontics / Dental materials science and

Research Keywords

• bone，dental implant

Affiliated Academic Societies

• Japan Prosthodontic Society

Educational Activity

Course in Charge

1. 2024, Undergraduate Education, First Semester, Early Clinical Exposure I
2. 2024, Undergraduate Education, 3Term, Prosthetic Dentistry I
3. 2024, Undergraduate Education, 4Term, Prosthetic Dentistry II
4. 2024, Undergraduate Education, 3Term, Removable Prosthodontics I
5. 2024, Undergraduate Education, 4Term, Removable Prosthodontics II
6. 2024, Undergraduate Education, Second Semester, Early Clinical Exposure II
7. 2024, Undergraduate Education, 2Term, Oral Implantology
8. 2024, Undergraduate Education, 1Term, Basic Practice of Functional and Regenerative Oral Medicine I
9. 2024, Undergraduate Education, 2Term, Basic Practice of Functional and Regenerative Oral Medicine II
10. 2024, Undergraduate Education, 1Term, Practice of Prosthodontic Treatment for Edentulous Patients I
11. 2024, Undergraduate Education, 2Term, Practice of Prosthodontic Treatment for Edentulous Patients II
12. 2024, Undergraduate Education, First Semester, Dental Research Practices I
13. 2024, Undergraduate Education, 3Term, Practice of Prosthodontic Treatment for Partial Edentulous Patients I
14. 2024, Undergraduate Education, 4Term, Practice of Prosthodontic Treatment for Partial Edentulous Patients II
15. 2024, Undergraduate Education, 3Term, Basic Practice of Dental Prosthesis I
16. 2024, Undergraduate Education, 4Term, Basic Practice of Dental Prosthesis II
17. 2024, Undergraduate Education, Second Semester, Early Clinical Exposure III
18. 2024, Undergraduate Education, Second Semester, Dental Research Practices II
19. 2024, Undergraduate Education, 2Term, Advanced Course in Functional and Regenerative Oral Medicine
20. 2024, Undergraduate Education, 2Term, General Dentistry III
21. 2024, Undergraduate Education, First Semester, Dental Research Practices III
22. 2024, Undergraduate Education, Academic Year, Clinical Practice (Denture Prosthodontics I)
23. 2024, Undergraduate Education, Academic Year, Clinical Practice (Denture Prosthodontics II)
24. 2024, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering
25. 2024, Undergraduate Education, First Semester, Clinical Practice in Oral Health Engineering
26. 2024, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering
27. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Advanced Prosthodontics
28. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Advanced Prosthodontics
29. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Advanced Prosthodontics
30. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Advanced Prosthodontics

Research Activities

Academic Papers

1. Investigation to Predict Primary Implant Stability Using Frictional Resistance Torque of Tap Drilling, Journal of Oral & Maxillofacial Research, 13(4), e1, 202212
2. Osseointegration Aspects of Implants at the Bone Reconstruction Site by a Novel Porous Titanium Scaffold, J Oral Maxillofac Res, 12(3), e4, 2021
3. Novel fabrication of porous titanium by a resin-impregnated titanium substitution technique for bone reconstruction., RSC ADVANCES, 9(3), 1625-1631
4. Histological and Bone Morphometric Evaluation of Osseointegration Aspects by Alkali Hydrothermally-Treated Implants, APPLIED SCIENCES-BASEL, 8(4), 635-635, 2018
5. Comparative Study of Surface Modification Treatment for Porous Titanium., Journal of Oral & Maxillofacial Research, 2020
6. ★, Effects of intermittent continual administration of parathyroid hormone on implant stability in the presence of osteoporosis: an in vivo study using resonance frequency analysis in a rabbit model., JOURNAL OF APPLIED ORAL SCIENCE, 25(5), 498-505
7. Novel development of phosphate treated porous hydroxyapatite., MATERIALS, 10(12), 1405
8. Investigation of effective modification treatments for thin titanium membranes., APPLIED SCIENCES-BASEL, 7(10), 1022-1022
9. Stability of implants placed in bone reconstructed with block-type interconnected porous hydroxyapatite., JOURNAL OF HARD TISSUE BIOLOGY, 26(4), 393-397
10. Enhanced osseointegration of a modified titanium implant with bound phosphor threonine: a preliminary in vivo study., Journal of Functional Biomaterials, 8(2), E16-E16
11. A stability evaluation of a novel titanium dental implant/interconnected porous hydroxyapatite complex under functional loading conditions., DENTAL MATERIALS JOURNAL, 36(5), 647-653
12. Intermittent administration of parathyroid hormone enhances primary stability of dental implants in a bone-reduced rabbit model., JOURNAL OF ORAL SCIENCE, 58(2), 241-246
13. Osseointegration aspects of placed implant in bone reconstruction with newly developed block-type interconnected porous hydroxyapatite., Journal of applied oral science, 24(4), 325-331
14. Influence of implant surface topography on primary stability in a standardized osteoporosis rabbit model study, Journal of functional biomaterial, 6(1), 143-152
15. Effect of autoclave heat sterilization on the surface properties of the sodium titanate hydrogel layer on the alkali-treated titanium membrane., 85-90

Invited Lecture, Oral Presentation, Poster Presentation

1. Novel method of predictable primary implant stability using frictional resistance torque of tap drilling measurement, Kaien Wakamatsu, Kazuya Doi, Yusuke Makihara, Yoshifumi Oki, Reiko Kobatake, Takayasu Kubo and Kazuhiro Tsuga, 2022/06, Without Invitation, English
2. Newly development of porous titanium bone reconstruction material which enables implant treatment., Wakamatsu K, Doi K, Kobatake R, Makihara Y, Oki Y, Umehara H, Kubo T, Tsuga K, 7th Biennial joint congress of JPS-CPS-KAP, 2021/02, Without Invitation, Japanese
3. Evaluation of alkali treatment for porous titanium as bone reconstruction material., Kobatake R, Doi K, Makihara Y, Oki Y, Umehara H, Kubo T, Tsuga K, 98th General session & exhibition of the IADR, 2020/.3, Without Invitation, English, experimental
4. A case report applying newly developed interconnected porous hydroxyapatite to implant GBR., Makihara Y, Doi K, Oki Y, Kobatake R, Umehara H, Kubo T, Tsuga K, DENTISPHERE 4-International Scientific Meeting, 5th Asean plus, Tokushima joint international conference, 2019/11, Without Invitation, English, other
5. The bioactive effect of alkali treated titanium membrane., Umehara H, Doi K, Kobatake R, Oki Y, Makihara Y, Kubo T, Tsuga K, DENTISPHERE 4-International Scientific Meeting, 5th Asean plus, Tokushima joint international conference, 2019/11, Without Invitation, Japanese, experimental
6. Novel fabrication of bioactive porous titanium for bone reconstruction., Kobatake R, Doi K, Makihara Y, Oki Y, Umehara H, Oue H, Abe Y, Kubo T, Tsuga K, DENTISPHERE 4-International Scientific Meeting, 5th Asean plus, Tokushima joint international conference, 2019/11, Without Invitation, English, experimental
7. Novel bioactive titanium membrane for bone regeneration ; effect of alkali treatment., Umehara H, Doi K, Kobatake R, Makihara Y, Oki Y, Kubo T, Tsuga K, European Association for Osseointegration 28th Annual Scientific Meeting, 2019/.9, Without Invitation, English, Lisbon, experimental
8. Development of novel bioactive porous titanium for bone reconstruction material., 2019/.6, Without Invitation, Japanese, experimental
9. Intermittent parathyroid hormone administration enhances implant stability in osteoporosis model., Oki Yoshifumi, Doi Kazuya, Makihara Yusuke, Kubo Takayasu, Tsuga Kazuhiro, 27th Annual Scientific Meeting of European Association for Osseointegration, 2018, Without Invitation, English, Wien, experimental
10. Development of novel porous titanium as bone reconstruction material., Kobatake R, Doi K, Makihara Y, Oki Y, Kubo T, Abekura H, Tsuga K, 7th Hiroshima Conference on Education and Science in Dentistry, 2018, Without Invitation, English, Hiroshima, experimental
11. Investigation of material property and bioactivity of novel developed bioactive titanium membrane., Umehara H, Doi K, Kobatake R, Oki Y, Kubo T, Tsuga K, The 11th Congress of the Asian Academy of Osseointegration, 2018, Without Invitation, English, Souru, experimental
12. Physical and biological characteristics of a novel-porous-titanium for bone reconstruction., Kobatake R, Doi K, Oki Y, Makihara Y, Kubo T, Tsuga K, International Association for Dental Research, 2018, Without Invitation, English, London, experimental
13. Osseointegration aspect of implants placed in bone reconstructed site with novel porous titanium., Kobatake R, Doi K, Oki Y, Yokoi M, Makihara Y, Umehara H, Kubo T, Tsuga K, 27th Annual Scientific Meeting of European Association for Osseointegration, 2018, Without Invitation, English, Wien, experimental
14. Intermittent parathyroid hormone administration enhances implant stability in osteoporosis model., Oki Y, Doi K, Makihara Y, Kubo T, Tsuga K, International Association for Dental Research, 2017, Without Invitation, English, Snafrancisco, experimental
15. Bioactive surface modification of titanium membrane., Oki Y, Doi K, Kobatake R, Yokoi M, Kato K, Kubo T, Tsuga K, 26th Annual Scientific Meeting of European Association for Osseointegration, 2017, Without Invitation, English, Madrid, experimental
16. Newly development of porous titanium structure for bone graft material., Kobatake R, Doi K, Oki Y, Makihara Y, Koretake K, Kubo T, Tsuga K, 26th Annual Scientific Meeting of European Association for Osseointegration, 2017, Without Invitation, English, Madrid, experimental
17. Intermittent parathyroid hormone administration is effective to achieve favourable primary stability and osseointegration in rabbit osteoporosis model., Oki Y, Doi K, Makihara Y, Kubo T, Tsuga K, he 11th Scientific Meeting of the Asian Academy of Osseointegration, 2016, Without Invitation, English, Bangkok, experimental
18. Implant stability under functional loading in reconstructed sites with interconnected porous hydroxyapatite., Makihara Y, Doi K, Kubo T, Oki Y, Tsuga K, The 11th Scientific Meeting of the Asian Academy of Osseointegration, 2016, Without Invitation, English, Bangkok, experimental
19. Development of novel porous titanium structure for bone reconstruction material., Kobatake R, Doi K, Oki Y, Makihara Y, Oue H, Kubo T, Tsuga K, 2016, Without Invitation, English, experimental
20. Effect of intermittent parathyroid hormone administration on osseointegration aspects in rabbit osteoporosis model., Oki Y, Doi K, Makihara Y, Kubo T, Tsuga K, 6th Hiroshima Conference on Education and Science in Dentistry, 2015, Without Invitation, English, experimental
21. Effect of intermittent parathyroid hormone (PTH) administration on osseointegration aspects in rabbit osteoporosis model., Doi K, Kubo T, Oki Y, Makihara Y, Tsuga K, The 24th European Association for Osseointegration annual scientific meeting, 2015, Without Invitation, English, Stockholm, experimental
22. Intermittent parathyroid hormone administration enhances primary stability and osseointegration on glucocorticoid induced osteoporosis., Doi K, Kubo T, Oki Y, Makihara Y, Tsuga K, 6th Hiroshima Conference on Education and Science in Dentistry, 2015, Without Invitation, English, experimental
23. Effect of intermittent parathyroid hormone administration on primary stability in rabbit osteoporosis model., Doi K, Kubo T, Makihara Y, Oue H, Kato K, Oki Y, Akagawa Y, Tsuga K, The 9 th Scientific Meeting of the Asian Academy of Osseointegration, 2014, Without Invitation, English, experimental
24. Effect of intermittent parathyroid hormone(PTH) administration on primary stability in osteoporosis rabbit model., Oue H, Doi K, Oki Y, Makihara Y, Kajihara S, Koretake K, Kubo T, Akagawa Y, Tsuga K, The 23rd European Association for Osseointegration, 2014, Without Invitation, English, Rome, experimental
25. Osseointegration aspects of placed implant in bone reconstruction with newly developed porous titanium, Kobatake R, Doi K, Makihara Y, Oki Y, Umehara H, Kubo T, Gruber H, Tsuga K, 7th Biennial Joint Congress of JPS-CPS-KAP, 2021/02, Without Invitation, English, experimental

Awards

1. 2015, poster award, Intermittent parathyroid hormone administration enhances primary stability and osseointegration on glucocorticoid induced osteoporosis.

External Funds

Acceptance Results of Competitive Funds

1. 2020, 2021
2. 2022, 2024
3. 2018, 2019