Masami Kanawa

Last Updated :2025/05/09

Affiliations, Positions
Natural Science Center for Basic Research and Development, Assistant Professor
E-mail
mfukuhiroshima-u.ac.jp
Self-introduction
I am interested in mesenchymal stromal cells (MSC), which is one of the cells used in regenerative medicine. MSC can differentiate into various cell types, bone, cartilage, fat, etc., but their differentiation potentials are variable, and depend on individual strain. Currently, MSC is defined by the expression of several types of surface markers, but since these surface antigens cannot evaluate accurately the differentiation potential of MSC. Therefore, my work is to investigate markers of MSC, which are able to evaluate their differentiation potentials from among the genes expressed in MSC.

Basic Information

Academic Degrees

  • Dr. dentistry, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Plastic surgery

Research Keywords

  • mesenchymal stem cell
  • osteogenesis
  • adipogenesis
  • chondrogenesis
  • differentiation predict marker

Affiliated Academic Societies

  • The Japanese Society for Regenerative Medicine
  • The Molecular Biology Society of Japan

Research Activities

Academic Papers

  1. The Effect of Mixed Polymethylmethacrylate and Hydroxyapatite on Viability of Stem Cell from Human Exfoliated Deciduous Teeth and Osteoblast, EUROPEAN JOURNAL OF DENTISTRY, 18(01), 314-320, 202402
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  2. Achaete-scute family bHLH transcription factor 2 activation promotes hepatoblastoma progression, CANCER SCIENCE, 115(3), 847-858, 202403
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  3. Polymethylmethacrylate-hydroxyapatite antibacterial and antifungal activity against oral bacteria: An in vitro study, JOURNAL OF TAIBAH UNIVERSITY MEDICAL SCIENCES, 19(1), 190-197, 202402
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  4. Oncogenic Role of ADAM32 in Hepatoblastoma: A Potential Molecular Target for Therapy, CANCERS, 14(19), 202210
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  5. Study of Alveolar Bone Remodeling Using Deciduous Tooth Stem Cells and Hydroxyapatite by Vascular Endothelial Growth Factor Enhancement and Inhibition of Matrix Metalloproteinase-8 Expression in vivo, CLINICAL COSMETIC AND INVESTIGATIONAL DENTISTRY, 14, 71-78, 2022
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  6. Selection of common markers for bone marrow stromal cells from various bones using real-time RT-PCR: Effects of passage number and donor age, TISSUE ENGINEERING, 13(10), 2405-2417, 200710
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  7. Impact of Zinc Fingers and Homeoboxes 3 on the Regulation of Mesenchymal Stem Cell Osteogenic Differentiation, STEM CELLS AND DEVELOPMENT, 20(9), 1540-1548, 201109
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  8. ★, Actinobacillus actinomycetemcomitans induces lethal effects on the macrophage-like human cell line U937., Oral Microbiolgy and Immunity, 16(5), 284-289, 20010401
  9. Comprehensive analysis of chemotactic factors for bone marrow mesenchymal stem cells, Stem Cells Develop, 16, 119-129, 20070401
  10. Comprehensive analysis of chemotactic factors for bone marrow mesenchymal stem cells., Stem Cells and Developmen, 16(1), 119-29, 20070201
  11. Feasibility and limitations of the round robin test for assessment of in vitro chondrogenesis evaluation protocol in a tissue-engineered medical product, JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 6(7), 550-558, 201207
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  12. Age-dependent decrease in the chondrogenic potential of human bone marrow mesenchymal stromal cells expanded with fibroblast growth factor-2, CYTOTHERAPY, 15(9), 1062-1072, 201309
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  13. Characteristic expression of MSX1, MSX2, TBX2 and ENTPD1 in dental pulp cells, BIOMEDICAL REPORTS, 3(4), 566-572, 201507
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  14. High glucose promotes TGF-beta 1 production by inducing FOS expression in human peritoneal mesothelial cells, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 20(1), 30-38, 201602
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  15. DEC2 is a negative regulator for the proliferation and differentiation of chondrocyte lineage-committed mesenchymal stem cells, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 38(3), 876-884, 201609
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  16. Characterization of human dental pulp cells grown in chemically defined serum-free medium, BIOMEDICAL REPORTS, 8(4), 350-358, 2018
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  17. Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal Fibrosis, Stem Cells Transl Med, 20180930
  18. Genetic Markers Can Predict Chondrogenic Differentiation Potential in Bone Marrow-Derived Mesenchymal Stromal Cells, STEM CELLS INTERNATIONAL, 2018
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  19. Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal Fibrosis, STEM CELLS TRANSLATIONAL MEDICINE, 7(12), 893-905, 201812
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  20. Potential Marker Genes for Predicting Adipogenic Differentiation of Mesenchymal Stromal Cells, APPLIED SCIENCES-BASEL, 9(14), 20190702
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  21. The Identification of Marker Genes for Predicting the Osteogenic Differentiation Potential of Mesenchymal Stromal Cells, CURRENT ISSUES IN MOLECULAR BIOLOGY, 43(3), 2157-2166, 202112
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Invited Lecture, Oral Presentation, Poster Presentation

  1. Effect of Mesenchymal Stem Cells on Mixed Self Assembled Monolayer, *Hirata I, Veronica SR, Tania , Yamauchi Y, Kanawa M, Kato , Kato K, The International Dental Materials congress 2016, 2016/11/04, Without Invitation, English, experimental