AKINORI AWAZU

Last Updated :2024/02/01

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Associate Professor
E-mail
awahiroshima-u.ac.jp
Self-introduction
0

Basic Information

Major Professional Backgrounds

  • 2006/11/01, 2007/03/31, Hiroshima University, Graduate School of Science, Research Associate
  • 2007/04/01, 2011/09/30, Hiroshima University, Graduate School of Science, Assistant Professor
  • 2011/10/01, 2019/03/31, Hiroshima University, Graduate School of Science, Associate Professor

Educational Backgrounds

  • Osaka Prefecture University, Japan, 1999/04, 2001/03
  • Ibaraki University, Japan, 1997/04, 1999/03
  • Ibaraki University, Japan, 1993/04, 1997/03

Academic Degrees

  • Doctor of Engineering, Osaka Prefecture University
  • Master, Ibaraki University

Educational Activity

  • [Bachelor Degree Program] School of Science : Mathematics : Mathematics
  • [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Mathematical and Life Sciences
  • [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Mathematical and Life Sciences

Research Fields

  • Biological Sciences;Genome science;Genome biology
  • Biology;Basic biology;Genetics / Chromosome dynamics
  • Informatics;Frontiers of informatics;Life / Health / Medical informatics
  • Agricultural sciences;Animal life science;Veterinary medical science
  • Biology;Biological Science;Biophysics

Research Keywords

  • Theoretical Biology

Affiliated Academic Societies

  • Physical Society of Japan
  • Biophysical Society of Japan
  • Society of Plant Physiology of Japan

Educational Activity

Course in Charge

  1. 2023, Undergraduate Education, 4Term, Mathematics for Computation
  2. 2023, Undergraduate Education, 4Term, Exercises in Mathematics for Computation
  3. 2023, Undergraduate Education, 3Term, elementary nonlinear studies
  4. 2023, Undergraduate Education, First Semester, Special Study of Mathematics and Informatics for Graduation
  5. 2023, Undergraduate Education, Second Semester, Special Study of Mathematics and Informatics for Graduation
  6. 2023, Graduate Education (Master's Program) , 1Term, Special Lectures in Integrated Sciences for Life
  7. 2023, Graduate Education (Master's Program) , 1Term, Introduction to Applied Mathematics and Computational Science
  8. 2023, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Mathematical and Life Sciences
  9. 2023, Graduate Education (Master's Program) , 4Term, Mathematical Modeling B
  10. 2023, Graduate Education (Master's Program) , 2Term, High-Performance Computing and Data Science
  11. 2023, Graduate Education (Master's Program) , 2Term, Topical Seminar in Mathematical Science A
  12. 2023, Graduate Education (Master's Program) , 4Term, Topical Seminar in Mathematical Science B
  13. 2023, Graduate Education (Master's Program) , First Semester, Exercises in Applied Mathematics and Computational Science A
  14. 2023, Graduate Education (Master's Program) , Second Semester, Exercises in Applied Mathematics and Computational Science B
  15. 2023, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences

Research Activities

Academic Papers

  1. The crucial role of CTCF in mitotic progression during early development of sea urchin, DEVELOPMENT GROWTH & DIFFERENTIATION, 65(7), 395-407, 202309
  2. ★, Formation of Small-World Network Containing Module Networks in Globally and Locally Coupled Map System with Changes in Global Connection with Time Delay Effects, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 92(3), 20230214
  3. Identification of aberrant transcription termination at specific gene loci with DNA hypomethylated transcription termination sites caused by DNA methyltransferase deficiency, GENES & GENETIC SYSTEMS, 97(3), 139-152, 202206
  4. Methylome data derived from maternal-zygotic DNA methyltransferase 3aa(-/-) zebrafish, DATA IN BRIEF, 44, 202210
  5. Molecular dynamics analysis of biomolecular systems including nucleic acids, BIOPHYSICS AND PHYSICOBIOLOGY, 19, 2022
  6. ★, Epigenetic-structural changes in X chromosomes promote Xic pairing during early differentiation of mouse embryonic stem cells, BIOPHYSICS AND PHYSICOBIOLOGY, 19, 2022
  7. Ants Alter Collective Behavior After Feeding and Generate Shortcut Paths on a Two-Dimensional Foraging Area, FRONTIERS IN PHYSICS, 10, 20220511
  8. ★, Partial exogastrulation due to apical-basal polarity of F-actin distribution disruption in sea urchin embryo by omeprazole, GENES TO CELLS, 27(6), 392-408, 202206
  9. ★, Mathematical model of chromosomal dynamics during DNA double strand break repair in budding yeast, BIOPHYSICS AND PHYSICOBIOLOGY, 19, 2022
  10. ★, Ribosomal protein L5 facilitates rDNA-bundled condensate and nucleolar assembly, LIFE SCIENCE ALLIANCE, 5(7), 202207
  11. ★, Self-Organization of Diverse Directional Hierarchical Networks in Simple Coupled Maps with Connection Changes, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 91(2), 20220215
  12. Structural dynamics of DNA depending on methylation pattern, PHYSICAL REVIEW E, 103(1), 20210111
  13. ★, Spontaneous Organizations of Diverse Network Structures in Coupled Logistic Maps with a Delayed Connection Change, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 89(11), 20201115
  14. ★, Ultrasensitive Change in Nucleosome Binding by Multiple Phosphorylations to the Intrinsically Disordered Region of the Histone Chaperone FACT, JOURNAL OF MOLECULAR BIOLOGY, 432(16), 4637-4657, 20200724
  15. ★, Affinity of rhodopsin to raft enables the aligned oligomer formation from dimers: Coarse-grained molecular dynamics simulation of disk membranes, PLOS ONE, 15(2), 20200207
  16. Simple Particle Model for Low-Density Granular Flow Interacting with Ambient Fluid, GEOSCIENCES, 10(2), 202002
  17. Histone Tail Dynamics in Partially Disassembled Nucleosomes During Chromatin Remodeling, FRONTIERS IN MOLECULAR BIOSCIENCES, 6, 20191128
  18. Establishment of knockout adult sea urchins by using a CRISPR-Cas9 system, DEVELOPMENT GROWTH & DIFFERENTIATION, 61(6), 378-388, 201908
  19. Verification of mathematical models of response threshold through statistical characterisation of the foraging activity in ant societies, SCIENTIFIC REPORTS, 9, 20190620
  20. Diverse stochasticity leads a colony of ants to optimal foraging, JOURNAL OF THEORETICAL BIOLOGY, 465, 7-16, 20190321
  21. ★, Insulator Activities of Nucleosome-Excluding DNA Sequences without Bound Chromatin Looping Proteins, JOURNAL OF PHYSICAL CHEMISTRY B, 123(5), 1035-1043, 20190207
  22. ★, Torsional Turning Motion of Chromosomes as an Accelerating Force to Align Homologous Chromosomes during Meiosis, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 88(2), 20190215
  23. Chromosomal Abnormalities in Human Lymphocytes after Computed Tomography Scan Procedure, RADIATION RESEARCH, 190(4), 424-432, 201810
  24. ★, Broad distribution spectrum from Gaussian to power law appears in stochastic variations in RNA-seq data, SCIENTIFIC REPORTS, 8, 20180529
  25. Reciprocating Motion of a Self-Propelled Rotor Induced by Forced Halt and Release Operations, JOURNAL OF PHYSICAL CHEMISTRY C, 122(6), 3482-3487, 20180215
  26. Dynamic changes in the interchromosomal interaction of early histone gene loci during development of sea urchin, JOURNAL OF CELL SCIENCE, 130(24), 4097-4107, 201712
  27. ★, Excluded volume effect enhances the homology pairing of model chromosomes, IEICE NONLINEAR THEORY AND ITS APPLICATIONS, 7(2), 66-75, 2016
  28. ★, The 1-Particle-per-k-Nucleotides (1PkN) Elastic Network Model of DNA Dynamics with Sequence-Dependent Geometry, FRONTIERS IN PHYSIOLOGY, 8, 20170314
  29. ★, Prediction of nucleosome positioning by the incorporation of frequencies and distributions three different nucleotide segment lengths into a general pseudo k-tuple nucleotide composition, BIOINFORMATICS, 33(1), 42-48, 20170101
  30. A new application of the phase-field method for understanding the mechanisms of nuclear architecture reorganization, JOURNAL OF MATHEMATICAL BIOLOGY, 74(1-2), 333-354, 201701
  31. The Flux of Euglena gracilis Cells Depends on the Gradient of Light Intensity, PLOS ONE, 11(12), 20161229
  32. Risk stratification of ventricular fibrillation in Brugada syndrome using noninvasive scoring methods, HEART RHYTHM, 13(10), 1947-1954, 201610
  33. ★, Cilia play a role in breaking left-right symmetry of the sea urchin embryo, GENES TO CELLS, 21(6), 568-578, 201606
  34. ★, Simple Elastic Network Models for Exhaustive Analysis of Long Double-Stranded DNA Dynamics with Sequence Geometry Dependence, PLOS ONE, 10(12), 20151201
  35. ★, Noise-plasticity correlations of gene expression in the multicellular organism Arabidopsis thaliana, JOURNAL OF THEORETICAL BIOLOGY, 387, 13-22, 20151221
  36. ★, Nuclear dynamical deformation induced hetero- and euchromatin positioning, PHYSICAL REVIEW E, 92(3), 20150914
  37. Deterioration of the circadian variation of heart rate variability in Brugada syndrome may contribute to the pathogenesis of ventricular fibrillation, JOURNAL OF CARDIOLOGY, 64(2), 133-138, 201408
  38. ★, Segregation and phase inversion of strongly and weakly fluctuating Brownian particle mixtures and a chain of such particle mixtures in spherical containers, PHYSICAL REVIEW E, 90(4), 20141017
  39. Localized Bioconvection Patterns and Their Initial State Dependency in Euglena gracilis Suspensions in an Annular Container, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 83(4), 201404
  40. Motion with Memory of a Self-Propelled Object, JOURNAL OF PHYSICAL CHEMISTRY C, 117(46), 24490-24495, 20131121
  41. Collective motion of symmetric camphor papers in an annular water channel, PHYSICAL REVIEW E, 88(1), 20130730
  42. ★, Influences of Excluded Volume of Molecules on Signaling Processes on the Biomembrane, PLOS ONE, 8(5), 20130502
  43. Stability of transverse dunes against perturbations: A theoretical study using dune skeleton model, AEOLIAN RESEARCH, 9, 63-68, 201306
  44. Collective Motion and Phase Transitions of Symmetric Camphor Boats, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 81(7), 201207
  45. Swarming of self-propelled camphor boats, PHYSICAL REVIEW E, 85(5), 20120507
  46. Segregation-pattern reorientation of a granular mixture on a horizontally oscillating tray, PHYSICAL REVIEW E, 85(4), 20120416
  47. Bifurcation Analysis of the Transition of Dune Shapes under a Unidirectional Wind, PHYSICAL REVIEW LETTERS, 108(15), 20120412
  48. Effective stochastic resonance of coupled excitable elements under noise of unequal amplitude, PHYSICAL REVIEW E, 84(2), 20110824
  49. Localized Bioconvection of Euglena Caused by Phototaxis in the Lateral Direction, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 80(6), 201106
  50. Effective stochastic resonance under noise of heterogeneous amplitude, PHYSICAL REVIEW E, 82(5), 20101117
  51. Saddle-node bifurcation to jammed state for quasi-one-dimensional counter-chemotactic flow, PHYSICAL REVIEW E, 82(2), 20100721
  52. Three-Dimensional Dune Skeleton Model as a Coupled Dynamical System of Two-Dimensional Cross Sections, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 79(6), 201006
  53. Collective behavior of inanimate boats, PHYSICAL REVIEW E, 81(5), 201005
  54. ★, Discreteness-induced slow relaxation in reversible catalytic reaction networks, PHYSICAL REVIEW E, 81(5), 201005
  55. ★, Ubiquitous glassy" relaxation in catalytic reaction networks", PHYSICAL REVIEW E, 80(4), 200910
  56. ★, Self-organized criticality of a catalytic reaction network under flow, PHYSICAL REVIEW E, 80(1), 200907
  57. Counter Chemotactic Flow in Quasi-One-Dimensional Path, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 78(7), 200907
  58. ★, Input-dependent wave propagations in asymmetric cellular automata: Possible behavior forward loop in biological reaction network, MATHEMATICAL BIOSCIENCES AND ENGINEERING, 5(3), 419-427, 200807
  59. ★, Network structure formation in pulsating particle populations, PHYSICAL REVIEW E, 76(5), 200711
  60. ★, Discreteness-induced transition in catalytic reaction networks, PHYSICAL REVIEW E, 76(4), 200710

Invited Lecture, Oral Presentation, Poster Presentation

  1. Insulator Activities of Nucleosome-Excluding DNA Sequences Without Chromatin Loop Form, Akinori Awazu, Yuki Matsushima, Naoaki Sakamo, The 57th Annual Meeting of Biophysical Society of Japan, 2019, With Invitation, English
  2. Chromatin segregation induced by nucleus envelope dynamical deformities, Akinori Awazu, THE 3RD HIROSHIMA INTERNATIONAL SYMPOSIUM ON FUTURE SCIENCE "FRONTIERS IN BIOIMAGING BASED LIFE SCIENCE", 2018, With Invitation, English
  3. Novel statistical model of fluctuating gene expression levels of Arabidopsis thaliana, Akinori Awazu, Atsushi J Nagano, The 55th Annual Meeting of the Biophysical Society of Japan, 2017, With Invitation, English
  4. Mathematical model of spatiotemporal dynamics of plant hormones responsible for plant stress response, 2020/09/16, Without Invitation, English
  5. A mathematical model of chromosomal dynamics in budding yeast during DNA double strand break, 2020/09/16, Without Invitation, English
  6. Analysis of physical properties and functionalities of ArsInsC and DNA repeat sequences, 2020/09/16, Without Invitation, English
  7. Self organized netowrk structures in coupled dynamical system with connection palasticity inspired by cerebral nervous system, 2020/09/16, Without Invitation, English
  8. The dynamics of chromosomes on early differentiation stage from ES cell, 2020/09/16, Without Invitation, English
  9. Modeling of sea urchin gastrulation based on cytoskeleton imaging, Kaichi Watanabe, Yuta Kurose, Yuhei Yasui, Naoaki Sakamoto, Akinori Awazu, 2020/09/16, Without Invitation, English
  10. Dynamic and cell specific changes in intranuclear chromosomal structures during early development of sea urchin, Yuhei Yasui, Ayaka Sugiyama , Naoaki Sakamoto , Akinori Awazu, 2020/09/16, Without Invitation, English

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2021, 2023
  2. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2017, 2019
  3. KAKENHI, 2014, 2015
  4. KAKENHI, 2013, 2014
  5. KAKENHI, 2012, 2013
  6. KAKENHI, Collective motion of self-propelled particles, 2011, 2012
  7. KAKENHI, Dynamics and Functions of Diverse Multi-Element Systems Accompanied by Fluctuation, 2010, 2012
  8. KAKENHI, Study of biological functions through formulation of the response theory of reaction network system, 2007, 2010