NOBUKI IMANO

Last Updated :2024/12/02

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medical), Assistant Professor
E-mail
imanohiroshima-u.ac.jp
Self-introduction
The development of cancer treatment is remarkable, and the latest findings are updated constantly. I would like to provide treatment that is tailored to the needs of each patient in person, based on the latest findings.

Basic Information

Educational Backgrounds

  • Hiroshima university, Faculty of Medicine

Academic Degrees

  • Hiroshima University

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, Year, Systemic Disease Control
  2. 2024, Undergraduate Education, Intensive, Practice of Medicine I
  3. 2024, Undergraduate Education, Intensive, Practice of Medicine II
  4. 2024, Graduate Education (Doctoral Program) , First Semester, Clinical Practicum in Medical Physics
  5. 2024, Graduate Education (Doctoral Program) , Second Semester, Clinical Practicum in Medical Physics

Research Activities

Academic Papers

  1. Outcome of Hypofractionated Radiotherapy for Localized Gastric Mucosa-associated Lymphoid Tissue Lymphoma., Anticancer research, 43(8), 202308
  2. Novel simulation for dosimetry impact of diaphragm respiratory motion in four-dimensional volumetric modulated arc therapy for esophageal cancer., Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 187, 202310
  3. Radiotherapy for Bone Metastase, Japanese Journal of Cancer and Chemotherapy, 50(3), 294-298, 20230315
  4. Incidence of and risk factors for non-hematologic toxicity with combined radiotherapy and CDK4/6 inhibitors in metastatic breast cancer using dose-volume parameters analysis: a multicenter cohort study, BREAST CANCER, 30(2), 282-292, 202303
    Link to Paper Search Results by DOI
  5. Long-term results of chemoradiotherapy with elective nodal irradiation for resectable locally advanced esophageal cancer in three-dimensional planning system, INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 28(3), 382-391, 202303
    Link to Paper Search Results by DOI
  6. Pre-Existing Interstitial Lung Abnormalities Are Independent Risk Factors for Interstitial Lung Disease during Durvalumab Treatment after Chemoradiotherapy in Patients with Locally Advanced Non-Small-Cell Lung Cancer, CANCERS, 14(24), 202212
    Link to Paper Search Results by DOI
  7. Radiation pneumonitis prediction model with integrating multiple dose-function features on 4DCT ventilation images, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 105, 202301
    Link to Paper Search Results by DOI
  8. Development of a radiomics and machine learning model for predicting occult cervical lymph node metastasis in patients with tongue cancer, ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 134(1), 93-101, 202207
    Link to Paper Search Results by DOI
  9. Clinical experience of volumetric modulated arc therapy for malignant pleural mesothelioma after extrapleural pneumonectomy., Journal of radiation research, 56(2), 2015
  10. Combined Ventilation and Perfusion Imaging Correlates With the Dosimetric Parameters of Radiation Pneumonitis in Radiation Therapy Planning for Lung Cancer., International journal of radiation oncology, biology, physics, 93(4), 2015
  11. Evaluation of adverse events in atomic bomb survivors receiving curative-intent radiation therapy from 2005 to 2010., Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 118(1), 2016
  12. Long-term results after 12-year follow-up of patients treated with whole-breast and boost irradiation after breast-conserving surgery., Japanese journal of radiology, 34(9), 2016
  13. Functional image-guided stereotactic body radiation therapy planning for patients with hepatocellular carcinoma., Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 42(2), 2017
  14. Clinical outcomes of concurrent chemoradiotherapy with volumetric modulated arc therapy in patients with locally advanced nasopharyngeal carcinoma., Japanese journal of radiology, 35(11), 2017
  15. Quantifying esophageal motion during free-breathing and breath-hold using fiducial markers in patients with early-stage esophageal cancer., PloS one, 13(6), 2018
  16. Long-term results of neoadjuvant chemoradiotherapy using cisplatin and 5-fluorouracil followed by esophagectomy for resectable, locally advanced esophageal squamous cell carcinoma., Journal of radiation research, 59(5), 2018
  17. Comparison of Stereotactic Body Radiation Therapy Combined With or Without Transcatheter Arterial Chemoembolization for Patients With Small Hepatocellular Carcinoma Ineligible for Resection or Ablation Therapies., Technology in cancer research & treatment, 17, 2018
  18. Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum., Journal of contemporary brachytherapy, 11(2), 2019
  19. Comparison of clinical outcome between computed tomography-based image-guided brachytherapy and two-dimensional-based brachytherapy for cervical cancer., Gynecologic oncology reports, 29, 2019
  20. Effect of bevacizumab against cystic components of brain tumors., Cancer medicine, 8(15), 2019
  21. Analysis of cardiac toxicity after definitive chemoradiotherapy for esophageal cancer using a biological dose-volume histogram., Journal of radiation research, 61(2), 2020
  22. An overview of stereotactic body radiation therapy for hepatocellular carcinoma., Expert review of gastroenterology & hepatology, 14(4), 2020
  23. Effectiveness of salvage radiotherapy for superficial esophageal Cancer after non-curative endoscopic resection., Radiation oncology (London, England), 15(1), 2020
  24. Long-term outcomes of induction chemotherapy followed by chemoradiotherapy using volumetric-modulated arc therapy as an organ preservation approach in patients with stage IVA-B oropharyngeal or hypopharyngeal cancers., Journal of radiation research, 61(4), 2020
  25. A Single Institution's Experience of Definitive Radiotherapy Using Volumetric-modulated Arc Therapy for Hypopharyngeal Cancers., Anticancer research, 40(7), 2020
  26. Distribution of Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma After Trimodal Therapy., Annals of surgical oncology, 28(3), 2021
  27. Metal artifact reduction techniques for single energy CT and dual-energy CT with various metal materials., BJR open, 1(1), 2019
  28. ★, Efficacy and tolerability of preoperative chemoradiotherapy with S-1 alone for locally advanced rectal cancer., Journal of radiation research, 62(2), 2021
  29. Long-term results of definitive chemoradiotherapy for unresectable locally advanced esophageal squamous cell carcinoma., Journal of radiation research, 62(1), 142-148, 202101
  30. ★, Evaluating Individual Radiosensitivity for the Prediction of Acute Toxicities of Chemoradiotherapy in Esophageal Cancer Patients., Radiation research, 195(3), 2021
  31. T2-FLAIR Mismatch Sign and Response to Radiotherapy in Diffuse Intrinsic Pontine Glioma., Pediatric neurosurgery, 56(1), 2021
  32. Brachytherapy with 198Au grains for cancer of the floor of the mouth: relationships between radiation dose and complications., Oral radiology, 38(1), 2022
  33. Treatment outcomes of real-time intraoral sonography-guided implantation technique of 198Au grain brachytherapy for T1 and T2 tongue cancer., Journal of radiation research, 62(5), 2021
  34. Predicting the Local Response of Esophageal Squamous Cell Carcinoma to Neoadjuvant Chemoradiotherapy by Radiomics with a Machine Learning Method Using 18F-FDG PET Images., Diagnostics (Basel, Switzerland), 11(6), 2021
  35. ★, Prediction of radiation pneumonitis after definitive radiotherapy for locally advanced non-small cell lung cancer using multi-region radiomics analysis., Scientific reports, 11(1), 2021
  36. Temporal changes and risk factors for esophageal stenosis after salvage radiotherapy in superficial esophageal cancer following non-curative endoscopic submucosal dissection., Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 166, 2022
  37. Reirradiation Using 198Au Grain Brachytherapy for Recurrent Oral Cancer Cases Previously Treated by Definitive Radiotherapy., Anticancer research, 42(1), 2022
  38. Investigating the displacement of radio-active sources during gold-198 grain brachytherapy for hospitalized oral cancer patients, JOURNAL OF CONTEMPORARY BRACHYTHERAPY, 14(2), 115-122, 2022
    Link to Paper Search Results by DOI
  39. A case of intrahepatic splenosis after splenic rupture with difficulty in preoperative diagnosis, Kanzo, 54(5), 317-325, 20130525
  40. Treatment outcomes of real-time intraoral sonography-guided implantation technique of Au-198 grain brachytherapy for T1 and T2 tongue cancer, JOURNAL OF RADIATION RESEARCH, 62(5), 871-876, 202109
    Link to Paper Search Results by DOI
  41. Brachytherapy with Au-198 grains for cancer of the floor of the mouth: relationships between radiation dose and complications, ORAL RADIOLOGY, 38(1), 105-113, 202201
    Link to Paper Search Results by DOI
  42. Reirradiation Using Au-198 Grain Brachytherapy for Recurrent Oral Cancer Cases Previously Treated by Definitive Radiotherapy, ANTICANCER RESEARCH, 42(1), 293-300, 202201
    Link to Paper Search Results by DOI
  43. ★, Potential benefits of volumetric modulated arc therapy to reduce the incidence of >= grade 2 radiation pneumonitis in radiotherapy for locally advanced non-small cell lung cancer patients, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 51(12), 1729-1735, 202112
    Link to Paper Search Results by DOI
  44. Development of a radiomics and machine learning model for predicting occult cervical lymph node metastasis in patients with tongue cancer., Oral surgery, oral medicine, oral pathology and oral radiology, 134(1), 2022
  45. Investigating the displacement of radio-active sources during gold-198 grain brachytherapy for hospitalized oral cancer patients., Journal of contemporary brachytherapy, 14(2), 2022
  46. Predictive role of circulatory levels of high-mobility group box 1 for radiation pneumonitis in patients with non-small cell lung cancer treated with definitive thoracic radiotherapy., International journal of clinical oncology, 2022
  47. Stereotactic body radiotherapy versus conventional radiotherapy for painful bone metastases: a systematic review and meta-analysis of randomised controlled trials., Radiation oncology (London, England), 17(1), 2022
  48. Incidence of and risk factors for non-hematologic toxicity with combined radiotherapy and CDK4/6 inhibitors in metastatic breast cancer using dose-volume parameters analysis: a multicenter cohort study., Breast cancer (Tokyo, Japan), 30(2), 202303
  49. Radiation pneumonitis prediction model with integrating multiple dose-function features on 4DCT ventilation images., Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), 105, 202301
  50. Pre-Existing Interstitial Lung Abnormalities Are Independent Risk Factors for Interstitial Lung Disease during Durvalumab Treatment after Chemoradiotherapy in Patients with Locally Advanced Non-Small-Cell Lung Cancer., Cancers, 14(24), 202212
  51. Long-term results of chemoradiotherapy with elective nodal irradiation for resectable locally advanced esophageal cancer in three-dimensional planning system., International journal of clinical oncology, 28(3), 202303
  52. ★, Pain Response Rates After Conventional Radiation Therapy for Bone Metastases Assessed Using International Consensus Pain Response Endpoints: A Systematic Review and Meta-Analysis of Initial Radiation Therapy and Reirradiation., International journal of radiation oncology, biology, physics, 116(4), 20230715
  53. Image masking using convolutional networks improves performance classification of radiation pneumonitis for non-small cell lung cancer., Physical and engineering sciences in medicine, 46(2), 202306
  54. Effectiveness of Spacers in Brachytherapy With 198Au Grains for Patients With Buccal Mucosa Cancer., Anticancer research, 43(5), 202305
  55. Quality of palliative radiotherapy assessed using quality indicators: a multicenter survey., Journal of radiation research, 20240624
  56. Efficacy of Supportive Care for Radiodermatitis in Patients with Head and Neck Cancer: Supplementary Analysis of an Exploratory Phase II Trial., Journal of personalized medicine, 13(9), 20230916
  57. Radiation doses of medical radiation workers performing low-dose-rate brachytherapy with 198Au grains and 192Ir pins for patients with oral cancers., Oral radiology, 40(2), 202404
  58. Pain response in single-fraction 8-Gy radiotherapy for painful non-bone-metastasis tumors: a single-center retrospective study., Journal of radiation research, 65(3), 20240523

Publications such as books

  1. 2023/10/12, Stereotactic Body Radiation Therapy Principles and Practices Second Edition, Oligomets., Springer, 2023, 10, Textbook, Joint work, English, pp94-pp97

Invited Lecture, Oral Presentation, Poster Presentation

  1. PNA-FISH and Gamma H2AX as possible predictors of radiotherapy-induced severe pneumonitis in lung cancer patients, CARAOS Gloriamaris Loy, IMANO Nobuki, SUN Jiying, TASHIRO Satoshi, The Japanese Radiation Research Society 66th annual meeting, 2023/11/06, Without Invitation, English
  2. THE Geriatric8 Screening tool predicts declining self-care ability in elderly patients with head and neck cancer during radiotherapy., Katsuta T, Fujioka M, Imano N, Hirokawa J, Nishibuchi I, Murakami Y, Nagata Y., The 6th Meeting of the Federation of Asian Organizations for Radiation Oncology(FARO), 2023/11/12, Without Invitation, English, Seoul, Korea
  3. Impact of the G8 score on treatment strategies and outcome in definitive radiotherapy for the elderly esophageal cancer patients., Nishibuchi I, Murakami Y, Miyoshi S, Katsuta T, Imano N, Hirokawa J, Nagata Y, American Society for Therapeutic Radiology and Oncology 65th the Annual Meeting (ASTRO 2023), 2023/10/01, Without Invitation, English, San Diego, USA
  4. Predictive modeling of radiation pneumonitis induced by chemoradiotherapy for locally advanced non-small cell lung cancer using radiomics and clinical features., Imano N, Kawahara D, Nishioka R, Koike K, Katsuta T, Hirokawa J, Saito A, Nishibuchi I, Murakami Y, Nagata Y, American Society for Therapeutic Radiology and Oncology 65th the Annual Meeting (ASTRO 2023), 2023/10/01, Without Invitation, English, San Diego, USA
  5. Quality of palliative radiation therapy assessed using quality indicators: A multicenter survey., Saito T, Shikama N, Takahashi T, Nakamura N, Aoyama H, Nakajima K, Koizumi M, Sekii S, Ebara T, Kiyohara H, Higuchi K, Yorozu K, Nishimura T, Ejima Y, Harada H, Araki N, Miwa M, Yamada K, Kawamoto T, Onishi H, Imano N, American Society for Therapeutic Radiology and Oncology 65th the Annual Meeting (ASTRO 2023), 2023/10/01, Without Invitation, English, San Diego, USA
  6. Laryngo-esophageal dysfunction free survival of chemoradiation for cervical esophageal cancer., Murakami Y, Miyoshi S, Katsuta T, Hirokawa J, Imano N, Nishibuchi I, Nagata Y, American Society for Therapeutic Radiology and Oncology 65th the Annual Meeting (ASTRO 2023), 2023/10/01, Without Invitation, English, San Diego, USA
  7. Radiomics-based decision support tool with GGO status of 5-year survival prediction for early-stage non-small cell lung cancer., Isobe R, Kawahara D, Nishioka R, Imano N, Nishibuchi I, Murakami Y, Nagata Y., American Association of Physicists in Medicine 65th annual meeting & exhibition(AAPM 2023), 2023/07/23, Without Invitation, English, Houston, USA
  8. Evaluation of reduced biological effective dose due to extended treatment course period., Takashita N, Saito A, Horinouchi S, Imano N, Nishibuchi I, Murakami Y, Ozawa S, Nagata Y., American Association of Physicists in Medicine 65th annual meeting & exhibition(AAPM 2023), 2023/07/23, Without Invitation, English, Houston, USA
  9. Clinical trials of SBRT for lung and liver cancers., Nobuki Imano, National Workshop on Introducing Stereotactic Body Radiation Therapy in Mongolia, 2024/06/19, With Invitation, English
  10. Tips for Contouring Head and Neck Cancer., Nobuki Imano, Yuji Murakami, IAEA / RAS6069 project ASPRONET education session, 2023/11/16, With Invitation, English, IAEA
  11. Novel simulation for dosimetry impact of diaphragm respiratory motion in 4D VMAT for esophageal cancer., Katsuta T, Kawahara D, Murakami Y, Miyoshi S, Imano N, Kubo K, Nishibuchi I, Nagata Y, ASTRO 2022 (American Society for Radiology Oncology 64th the Annual Meeting), 2022/10/23, Without Invitation, English, American Society for Radiology Oncology, Hybrid(WEB + San Antonio, USA)
  12. Usefulness of the G8 screening tool in determining treatment strategies for definitive radiotherapy of esophageal cancer in the elderly., Nishibuchi I, Murakami Y, Miyoshi S, Katsuta T, Imano N, Nagata Y, ASTRO 2022(American Society for Radiology Oncology 64th the Annual Meeting), 2022/10/23, Without Invitation, English
  13. Pre-existing interstitial lung abnormalities are independent risk factors for interstitial lung disease during durvalumab treatment after chemoradiotherapy in patients with locally advanced non–small lung cancer., Wakako Daido, Takeshi Masuda, Nobuki Imano, Naoko Matsumoto, Hiroyasu Shoda, Kosuke Hamai, Yasuo Iwamoto, Yusuke Takayama, Shohei Mishima, Ken Masuda, Shigeo Kawase, Yoshikazu Awaya, Yoshifumi Nishimura, Naoki Shiota, Nobuhisa Ishikawa, Masahiro Yamasaki, Soichi Kitaguchi, Kazunori Fujitaka, Yasushi Nagata, Noboru Hattori, ASCO Annual Meeting 2022, 2022/06/07, Without Invitation, English
  14. Novel simulation for dosimetry impact of diaphragm respiratory motion in 4D VMAT for esophageal cancer., Katsuta T, Kawahara D, Murakami Y, Miyoshi S, Imano N, Kubo K, Nishibuchi I, Nagata Y,, ASTRO 2022(American Society for Radiology Oncology 64th the Annual Meeting), 2022/10/23, Without Invitation, English
  15. Pain response rates after conventional radiation therapy for bone metastases assessed using International Consensus Pain Response Endpoints: A systematic review and meta-analysis of initial radiation therapy and re-irradiation, Nobuki Imano, Tetsuo Saito, Naoki Nakamura, Kei Ito, Atsunori Yorozu, Ikuno Nishibuchi, Yuji Murakami, Yasushi Nagata, The 64 th American Society for Radiation Oncology Annual Meeting, 2022/10/23, Without Invitation, English, American Society for Radiation Oncology, San Antonio
  16. Fractional irradiation and single irradiation for bone metastases, Nobuki Imano, IAEA/RCA PROJECT RAS 6098 REGIONAL TRAINING COURSE, 2022/12/07, With Invitation, English, IAEA/RCA, Web
  17. SBRT for Lung cancer, Nobuki Imano, HICARE/IAEA International Training Course on Advanced Radiation Therapy for Head and Neck, Lung, and Liver Cancer, 2022/11/15, With Invitation, English, HICARE/IAEA, Hiroshima
  18. Evaluating individual radiosensitivity to predict acute toxicities caused by chemoradiotherapy in esophageal cancer patients, Imano N, Kinugasa Y, Kawabata E, Sakai C, Ishida M, Nishibuchi I, Nagata Y, Tashiro S, The 6th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science, 2022/02/07, Without Invitation, English
  19. A prediction model for para-aortic lymph node metastasis in cervical cancer by radiomics analysis using pre-treatment MRI images of the primary tumor., Nishibuchi I, Kawahara d, Kawamura M, Kubo K, Imano N, Takeuchi Y, Saito A, Murakami Y, Nagata Y, ASTRO 2021(American Society for Therapeutic Radiology and Oncology 63rd the Annual Meeting), 2021/10, Without Invitation, English
  20. Prediction of radiation pneumonitis for NSCLC using crop convolutional neural network based model., Kawahara D, Imano N, Nishioka R, Saito A, Nagata Y, AAPM 2021(American Association of Physicists in Medicine 63rd annual meeting & exhibition), 2021/07, Without Invitation, English
  21. Association between acute toxicities of chemoradiotherapy and chromosomal aberrations in peripheral blood lymphocytes in esophageal cancer patients., Nobuki Imano, Nishibuchi I, Kawabata E, Kinugasa Y, Sakai C, Ishida M, Akita T, Kimura T, Murakami Y, Nagata Y, Tashiro S., Amercian Society for Radiation Oncology 62nd Annual Meeting, 2020/10/24, Without Invitation, English, Amercian Society for Radiation Oncology, Web
  22. Treatment outcome of short-course radiation in elderly patients with high grade glioma, Nobuki Imano, The 33th Annual Meeting of the Japanese Society for Radiation Oncology (JASTRO 2021), 2020/10/01, Without Invitation, Japanese, Web
  23. Novel index to predict non-hematologic acute toxicities caused by chemoradiotherapy in esophageal cancer patients, Imano N, Nishibuchi I, Kameoka T, Ochi M, Takeuchi Y, Takahashi I, Kimura T, Murakami Y, Tashiro S, Nagata Y, 2020/05/15, Without Invitation, Japanese
  24. Prediction of radiation pneumonitis after definitive radiotherapy for locally advanced non-small cell lung cancer using multi-region radiomics analysis, Nobuki Imano, Daisuke Kawahara, Riku Nishioka, Tomoki Kimura, Yasushi Nagata, The 5th FARO Meeting (Federation of Asian Organizations for Radiation Oncology), 2021/10/01, Without Invitation, English, Federation of Asian Organizations for Radiation Oncology, Web
  25. Survival prediction of locally advanced non-small cell lung cancer via machine learning techniques based on multi-region radiomics features and clinical risk factors., Nishioka R, Kawahara D, Imano N, Nagata Y, AAPM 2021(American Association of Physicists in Medicine 63rd annual meeting & exhibition), 2021/07, Without Invitation, English
  26. Potential benefits of volumetric modulated arc therapy to reduce the incidence of grade 2 radiation pneumonitis in radiotherapy for locally advanced non-small cell lung cancer patients., Imano N, Kimura T, Kawahara D, Kubo K, Takeuchi Y, Saito A, Nishibuchi I, Murakami Y, Nagata Y, ASTRO 2021(American Society for Therapeutic Radiology and Oncology 63rd the Annual Meeting), 2021/10, Without Invitation, English

Awards

  1. 2023/10/18, The 3rd IJCO Good Reviewer Award, International Journal of Clinical Oncology
  2. 2021/10/03, The 5th Meeting of the Federation of Asian Organizations for Radiation Oncology(FARO) Best proffered paper presentation, Third place, The Federation of Asian Organizations for Radiation Oncology(FARO)(President), Prediction of radiation pneumonitis after definitive radiotherapy for locally advanced non-small cell lung cancer using multi-region radiomics analysis.
  3. 2020/02/12, Young Researcher's Excellent Poster Session Award, International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science., Novel index to predict non-hematologic acute toxicities caused by chemoradiotherapy in esophageal cancer patients
  4. 2021/10/01, Best Proffered Paper Presentation, Federation of Asian Organizations for Radiation Oncology, Prediction of radiation pneumonitis after definitive radiotherapy for locally advanced non-small cell lung cancer using multi-region radiomics analysis

Social Activities

History as Peer Reviews of Academic Papers

  1. 2023, International Journal of Clinical Oncology, Others, 4
  2. 2024, International Journal of Clinical Oncology, Others, 3
  3. 2024, Japanese Journal of Radiology, Others, 2
  4. 2021, International journal of clinical oncology, Others, 3
  5. 2022, International journal of clinical oncology, Others, 7