KAZUYUKI HIROOKA

Last Updated :2025/06/23

Affiliations, Positions
Hiroshima University Hospital, Associate Professor
E-mail
kazuykhiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Kagawa Medical University

Affiliated Academic Societies

  • The Association for Research in Vision and Ophthalmology
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  • American Academy of Ophthalmology
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Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, Year, Clinical diagnosis and treatment II
  2. 2025, Undergraduate Education, Intensive, Practice of Medicine I
  3. 2025, Undergraduate Education, 1Term, Ophthalmology

Research Activities

Academic Papers

  1. One-Year Outcomes of Gonio Scratch as a Minimally Invasive Glaucoma Surgery with Cataract Removal, J Glaucoma, 34(6), 468-475, 20250601
    Link to Paper Search Results by DOI
  2. Effects and recurrence of proton beam therapy for retinal detachment due to choroidal hemangioma in Sturge-Weber syndrome patients: A case report, MEDICINE (BALTIMORE), 104(22), e42065-e42065, 20250530
    Link to Paper Search Results by DOI
  3. The relationship between aldosterone-induced retinal ganglion cell loss, blood pressure, and intraocular pressure, Japanese Journal of Ophthalmology, 20250516
    Link to Paper Search Results by DOI
  4. Changes in corneal higher-order aberrations following PreserFlo MicroShunt implantation, SCIENTIFIC REPORTS, 15(1), 16748-16748, 20250514
    Link to Paper Search Results by DOI
  5. Surgical Outcomes after Trabeculotomy for Primary Congenital Glaucoma, Japanese Journal of Ophthalmology, 20250124
    Link to Paper Search Results by DOI
  6. Risk factors for transient ciliochoroidal detachment after goniotomy with the Kahook Dual Blade., Sci Rep, 14(1), 21725-21725, 20240917
    Link to Paper Search Results by DOI
  7. Prevalence of Normal-Tension Glaucoma in Patients With Primary Aldosteronism, Am J Ophthalmol, 269, 339-345, 20240914
    Link to Paper Search Results by DOI
  8. The Efficacy and Safety Associated with Switching from Concomitant Brimonidine and Ripasudil, or Brimonidine or Ripasudil Monotherapy to a Fixed Combination of Brimonidine and Ripasudil in Glaucoma Patients., J Clin Med, 13(14), 4158-4158, 20240716
    Link to Paper Search Results by DOI
  9. Effect of ripasudil after trabeculectomy with mitomycin C: a multicentre, randomised, prospective clinical study., BMJ Open Ophthalmol, 9(1), e001449-e001449, 20240702
    Link to Paper Search Results by DOI
  10. Potentially compromised systemic and local lactate metabolic balance in glaucoma, which could increase retinal glucose and glutamate concentrations., Sci Rep, 14(1), 3683-3683, 20240214
    Link to Paper Search Results by DOI
  11. A potential role for inflammatory cytokines in a rare late-onset capsular block syndrome: a case report., BMC Ophthalmol, 24(1), 53-53, 20240202
    Link to Paper Search Results by DOI
  12. Safety and Efficacy of the Rho-kinase Inhibitor (Ripasudil) in Bleb Needling after Trabeculectomy: A prospective Multicenter Study, J Clin Med, 13(1), 75-75, 20231222
    Link to Paper Search Results by DOI
  13. A Retrospective Study of Risk Factors Affecting Long-Term Outcomes Following Ab Interno Trabeculotomy and Goniotomy Concomitant with Phacoemulsification., Clinical Ophthalmology, 3563-3568, 20231122
    Link to Paper Search Results by DOI
  14. Ex-press implantetion versus trabeculctomy for long-term maintenance in patients with open-angle glaucoma., Clin Ophthalmol, 17, 2525-2537, 20230828
    Link to Paper Search Results by DOI
  15. Posterior sclerectomy for persistent serous retinal detachment with secondary glaucoma in Sturge-Weber syndrome: A case report., Medicine (Baltimore), 102(26), e34144-e34144, 20230630
    Link to Paper Search Results by DOI
  16. A multicenter phase II study on the safety of rho-kinase inhibitor (ripasudil) with needling for the patients after trabeculectomy, Contemp Clin Trials Commun, 33, 101160-101160, 20230604
    Link to Paper Search Results by DOI
  17. Effects of Ripasudil, a Rho-Kinase Inhibitor, on Scar Formation in a Mouse Model of Filtration Surgery., Current eye research, 48(9), 826-835, 20230529
    Link to Paper Search Results by DOI
  18. Vision-Related Quality of Life following Combined Cataract and Minimally Invasive Glaucoma Surgery or Cataract Surgery Alone in Glaucoma Patients., Journal of Clinical Medicine, 12(9), 3279-3279, 20230504
    Link to Paper Search Results by DOI
  19. Aqueous Flare Changes in Ex-PRESS Glaucoma Shunt Eyes After 4.7 Tesla High-Field Magnetic Resonance Imaging., Transl Vis Sci Technol, 12(5), 3-3, 20230501
    Link to Paper Search Results by DOI
  20. Blood flow in the optic nerve head in patients with primary aldosteronism., PLoS One, 18(4), e0285039-e0285039, 20230426
    Link to Paper Search Results by DOI
  21. Incidence and pre/post-treatment risk factors of glaucoma in Vogt-Koyanagi-Harada disease., International ophthalmology, 20230317
    Link to Paper Search Results by DOI
  22. Comparison of Mid-Term Outcomes between Microhook ab Interno Trabeculotomy and Goniotomy with the Kahook Dual Blade., Journal of Clinical Medicine, 12(2), 558-558, 20230110
    Link to Paper Search Results by DOI
  23. Corneal Endothelial Cell Loss after Ciliary Sulcus Placement of Ahmed Glaucoma Valve in Patients with Noninfectious Uveitic Glaucoma., Journal of Personal Medicine, 12(12), 2075-2075, 20221216
    Link to Paper Search Results by DOI
  24. Usefulness of critical flicker fusion frequency measurement and its laterality for evaluating compressive optic neuropathy due to pituitary neuroendocrine tumors., Neurosurg Rev, 46(1), 4-4, 20221206
    Link to Paper Search Results by DOI
  25. Aldosterone as a possible contributor to eye diseases., Endocrinology, bqac201, 20221203
    Link to Paper Search Results by DOI
  26. DRAINAGE RETINOTOMY IS A RISK FACTOR FOR SURGICAL FAILURE AFTER PARS PLANA VITRECTOMY IN PATIENTS WITH PRIMARY UNCOMPLICATED RHEGMATOGENOUS RETINAL DETACHMENT., Retina, 42(12), 2307-2314, 20221201
    Link to Paper Search Results by DOI
  27. Effect of the rho-kinase inhibitor ripasudil in needling with mitomycin C for the failure of filtering bleb after trabeculectomy: a cross-sectional study., BMC Ophthalmology, 22, 20221114
    Link to Paper Search Results by DOI
  28. Transient ciliochoroidal detachment after microhook ab interno trabeculotomy: Its frequency and potential risk factors., Frontiers in Medicine(Lausanne), 9, 1028645-1028645, 20221104
    Link to Paper Search Results by DOI
  29. A Case of Intraocular Proliferative Changes Caused by a Glaucoma Tube Device, CUREUS JOURNAL OF MEDICAL SCIENCE, 14(6), 20220630
    Link to Paper Search Results by DOI
  30. Irreversible intraocular pressure elevation as a complication of MIRAgel scleral buckling., Am J Ophthalmol Case Rep, 12, 45-48, 20220513
    Link to Paper Search Results by DOI
  31. Compromised blood flow in the optic nerve head after systemic administration of 2 aldosterone in rats: A possible rat model of retinal ganglion cell loss., Current eye research, 1-27, 20220218
    Link to Paper Search Results by DOI
  32. Dietary Vitamins A, C, and Potassium Intake Is Associated With Narrower Retinal Venular Caliber, Frontiers in medicine, 9, 818139-818139, 20220210
    Link to Paper Search Results by DOI
  33. Influence of Overhanging Bleb on Corneal Higher-Order Aberrations after Trabeculectomy., Journal of Clinical Medicine, 11(1), 177-177, 20211229
    Link to Paper Search Results by DOI
  34. The Efficacy, Safety and Satisfaction Associated with Switching from Brinzolamide 1% and Brimonidine 0.1% to a Fixed Combination of Brinzolamide 1% and Brimonidine 0.1% in Glaucoma Patients, Journal of clinical medicine, 10(22), 5228-5228, 20211110
    Link to Paper Search Results by DOI
  35. Association of Dietary Nutrient Intake with Early Age-Related Macular Degeneration in Japanese-Americans., Metabolites, 11(10), 673-673, 20210930
    Link to Paper Search Results by DOI
  36. Improvements in Optical Characteristics after Excision of an Overhanging Bleb Developed following Trabeculectomy, CASE REPORTS IN OPHTHALMOLOGICAL MEDICINE, 2021, 20210906
    Link to Paper Search Results by DOI
  37. Effect of acetazolamide for exudative retinal detachment in Sturge-Weber syndrome., Medicine Case Reports and Study Protocols, 2(9), 20210903
    Link to Paper Search Results by DOI
  38. Comparison of Efficacy between 120ﾟ and 180ﾟ Schlemm's Canal Incision Microhook Ab Interno Trabeculotomy., Journal of Clinical Medicine, 10(14), 3181-3181, 20210719
    Link to Paper Search Results by DOI
  39. Treatment outcomes in the neovascular glaucoma tube versus trabeculectomy study., Graefes Arch Clin Exp Ophthalmol, 20210614
    Link to Paper Search Results by DOI
  40. Photodynamic therapy for radiation maculopathy: A case report., Medicine Case Reports, 100(14), e24888-e24888, 20210409
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  41. Responsiveness to ripasudil may be a potential outcome marker for selective laser trabeculoplasty in patients with primary open-angle glaucoma., Scientific reports, 11(1), 5812-5812, 20210312
    Link to Paper Search Results by DOI
  42. Comparison of the Humphrey Field Analyzer and Photopic Negative Response of Focal Macular Electroretinograms in the Evaluation of the Relationship Between Macula Structure and Function., Frontiers in medicine, 8, 649971-649971, 20210226
    Link to Paper Search Results by DOI
  43. Assessment of primary open-angle glaucoma peripapillary and macular choroidal area using enhanced depth imaging optical coherence tomography, PLoS One, 15(4), e0231214-e0231214, 20200406
    Link to Paper Search Results by DOI
  44. Retinal ganglion cell loss in kinesin-1 cargo Alcadein a deficient mice, Cell death & disease, 11(3), 166-174, 20200303
    Link to Paper Search Results by DOI
  45. Retinal Nerve Fiber Layer Thickness Progression after Robotic-Assisted Laparoscopic Radical Prostatectomy in Glaucoma Patients, J Ophthalmol, 6576140-6576140, 20191206
    Link to Paper Search Results by DOI
  46. Intraocularpressure-lowering effects of Ripasudil: a potential outcome marker for Trabeculotomy., BMC ophthalmology, 19(1), 243-243, 20191202
  47. Changes in choroidal area following trabeculectomy: Long-term effect of intraocular pressure reduction, PLOS ONE, 14(3), 20190320
    Link to Paper Search Results by DOI
  48. Persistent metamorphopsia associated with branch retinal vein occlusion., PLoS One 13, 13(9), 20180920
  49. Peripapillary and macular choroidal area in patients with normal-tension glaucoma., PLoS One, 13(9), 20180913
  50. Changes in corneal endothelial cells after trabeculectomy and EX-PRESS shunt, BMC Ophthalmology, 18(1), 243, 20180910
  51. The effect of steep Trendelenburg positioning on retinal structure and function during robotic-assisted laparoscopic procedures., J Ophthalmol, 2018, 1-5, 20180613
  52. Influence of disc size on the diagnostic accuracy of cirrus spectral-domain optical coherence tomography in glaucoma., J Ophthalmol, 11, 1-5, 20180411
  53. Macular atrophy findings by optical coherence tomography angiography compared with fundus autofluorescence in treated exudative age-related macular degeneration., Retina, 0, 1-7, 20171128
  54. The effect of vitreomacular and cataract surgery on oxygen saturation in retinal vessels., Clin Ophthalmol, 11, 756-765, 20170421
  55. The relationship between the renin-angiotensin–aldosterone system and NMDA receptor-mediated signal and the prevention of retinal ganglion cell death., Invest Ophthalmol Vis Sci, 58, 1397-1403, 20170301
  56. Metamorphopsia associated with branch retinal vein occlusion., PLoS One, 11(4), 20160428
  57. Comparison of Macular Integrity Assessment (MAIA), MP-3, and the Humphrey Field Analyzer in the evaluation of the relationship between the structure and function of the macula., PLoS One, 11(3), 1-13, 20160314
  58. Use of structure-function relationship in detecting glaucoma progression in early glaucoma., BMC Ophthalmol, 14(118), 1-5, 20141004
  59. Correlation between intraocular pressure fluctuation with postural change and postoperative intraocular pressure in relation to the time course after trabeculectomy., J Ophthalmol, 2014, 1-5, 20140717
  60. Treatment outcomes in the neovascular glaucoma tube versus trabeculectomy study, GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 259(10), 3067-3076, 202110
    Link to Paper Search Results by DOI
  61. Corneal Higher-Order Aberrations after Microhook ab Interno Trabeculotomy and Goniotomy with the Kahook Dual Blade: Preliminary Early 3-Month Results, JOURNAL OF CLINICAL MEDICINE, 10(18), 202109
    Link to Paper Search Results by DOI
  62. Determinants of corneal endothelial cell loss after sulcus placement of Ahmed and Baerveldt drainage device surgery, BRITISH JOURNAL OF OPHTHALMOLOGY, 105(7), 925-928, 202107
    Link to Paper Search Results by DOI
  63. Comparison of Efficacy between 120 degrees and 180 degrees Schlemm's Canal Incision Microhook Ab Interno Trabeculotomy, JOURNAL OF CLINICAL MEDICINE, 10(14), 202107
    Link to Paper Search Results by DOI
  64. Dysfunction of axonal transport in normal-tension glaucoma: a biomarker of disease progression and a potential therapeutic target., Neural regeneration research, 16(3), 506-507, 202103
    Link to Paper Search Results by DOI
  65. Comparison of Surgical Outcomes Between Microhook Ab Interno Trabeculotomy and Goniotomy with the Kahook Dual Blade in Combination with Phacoemulsification: A Retrospective, Comparative Case Series, ADVANCES IN THERAPY, 38(1), 329-336, 202101
    Link to Paper Search Results by DOI
  66. Determinants of corneal endothelial cell loss after sulcus placement of Ahmed and Baerveldt drainage device surgery., British journal of ophthalmology, 202007
    Link to Paper Search Results by DOI
  67. Effect of trabeculectomy on corneal endothelial cell loss, BRITISH JOURNAL OF OPHTHALMOLOGY, 104(3), 376-380, 202003
    Link to Paper Search Results by DOI
  68. Effectiveness of trabeculectomy with mitomycin C for glaucomatous eyes with low intraocular pressure on treatment eye drops, Acta Ophthalmol, 98(1), e81-e87, 202002
  69. Associations of nutrient intakes with glaucoma among Japanese Americans, Medicine (Baltimore), 98(49), e18314-e18314, 201912
  70. Visual acuity and corneal higher-order aberrations after EX-PRESS or trabeculectomy, and the determination of associated factors that influence visual function., Int Ophthalmol, 38(5), 1969-1976, 201810
  71. Clinical features of central serous chorioretinopathy with type I choroidal neovascularization., Am J Ophthalmol, 193, 80-86, 201809
  72. One-year outcomes of fixed treatment of intravitreal aflibercept for exudative age-related macular degeneration and the factor of visual prognosis., Medicine, 97(31), 1-8, 201808
  73. Oxygen venular saturation correlates with a functional loss in primary open-angle glaucoma and normal-tension glaucoma patients, Acta ophthalmologica, 96(3), e304-e308, 201805
  74. Paravascular inner retinal abnormalities in healthy eyes., Graefes Arch Clin Exp Ophthalmol, 255(9), 1743--8, 201709
  75. Relationship between oxygen saturation of the retinal vessels and visual field defect in glaucoma patients: comparison with each hemifield., Acta Ophthalmol, 94(8), 683-687, 201612
  76. Prevalence, characteristics, and pathogenesis of paravascular inner retinal defects associated with epiretinal membranes., Graefes Arch for Clin Exp Ophthalmol, 254(10), 1941-1949, 201610
  77. Estimating the rate of retinal ganglion cell loss to detect glaucoma progression: An observational cohort study., Medicine, 95(30), 1-5, 201607
  78. Elevated plasma aldosterone levels is associated with a reduction in retinal ganglion cell survival., J Renin Angioten Aldosterone Syst, 19(3), 2018
  79. Gene expression changes in the retina after systemic administration of aldosterone., Jpn J Ophthalmol, 62, 499-507, 2018
  80. Oxygen venular saturation correlates with a functional loss in primary open-angle glaucoma and normal-tension glaucoma patients., Ophthalmol, 96, 304-308, 2018
  81. Metamorphopsia associated with central retinal vein occlusion., PLoS One, 12(10), 1-12, 2017
  82. Vision-related quality of life following glaucoma filtration surgery., BMC Ophthalmol, 17(66), 2017
  83. Association between parafoveal capillary non-perfusion and macular function in eyes with branch retinal vein occlusion., Retina, 37, 1731-1737, 2017
  84. Retinal oxygen saturation before and after glaucoma surgery., Acta Ophthalmol, 95, 350-353, 2017
  85. Additive intraocular pressure lowering effects of the Rho kinase inhibitor, ripasudil, in glaucoma patients not able to obtain adequate control after other maximal tolerated medical therapy., Ad Ther, 33, 1628-1634, 2016
  86. Retinal oximetry in a healthy Japanese population., PLoS ONE, 11(7), 2016
  87. The relationship between vision-related quality of life and visual function in glaucoma patients., J Glaucoma,, 25, 505-509, 2016
  88. Change of regional choroid thickness after reduced-fluence photodynamic therapy for chronic central serous chorioretinopathy., Am J Ophthalmol, 159, 644-51, 2015
  89. Comparison of the toxicityprofile of benzalkonium chloride-preserved tafluprost and SofZia-preserved travoprost applied to the ocular surface., J Ocul Pharmacol Ther, 31, 156-164, 2015
  90. Effect of renin inhibitor aliskiren against retinal ischemia-reperfusion injury., Exp Eye Res, 122, 110-118, 2014
  91. Neuroprotection of granulocyte colony-stimulating factor during the acute phase of transient forebrain ischemia in gerbils., Brain Res, 1548, 49-55, 2014
  92. Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma., Cell Death Dis, 4(4), 711, 2013
  93. Evaluation of relationship between retinal nerve fiber layer thickness progression and visual field progression in patients with glaucoma., Jpn J Ophthalmol, 57, 451-456, 2013
  94. Modified vitreous surgery for symptomatic lamellar macular hole with epiretinal membrane containing macular pigment., Retina, 33, 1263-1269, 2013
  95. Correlation between the ganglion cell-inner plexiform layer thickness measured with cirrus HD-OCT and macular visual field sensitivity measured with microperimetry., Invest Ophthal Vis Sci, 54, 3046-3051, 2013
  96. Retinoic acid suppresses the adhesion and migration of human retinal pigment epithelial cells., Exp Eye Res, 109, 22-30, 2013
  97. Evaluation of peripapillary choroidal thickness in patients with normal-tension glaucoma., BMC Ophthalmol, 12, 29, 2012
  98. Comparison of optic nerve head parameters using Heidelberg Retina Tomograph 3 and spectral-domain optical coherence tomography., 40, 721-726, 2012
  99. Relationship between progression of visual field damage and choroidal thickness in eyes with normal-tension glaucoma., Clin Exp Ophthalmol, 40, 576-582, 2012
  100. Neuroprotective effects of angiotensin II type 1 receptor (AT1-R) blocker via modulating AT1-R signaling and decreased extracellular glutamate levels., Invest Ophthalmol Vis Sci, 53, 4099-4110, 2012
  101. Activation of the aldosterone/mineralocorticoid receptor system and protective effects of mineralocorticoid receptor antagonism in retinal ischemia-reperfusion injury., Exp Eye Res, 96, 116-123, 2012
  102. Edaravone, a free radical scavenger, attenuates behavioral deficits following transient forebrain ischemia by inhibiting oxidative damage in gerbils., Neurosci Lett, 506, 28-32, 2012
  103. Deleterious role of anti-high mobility group box 1 monoclonal antibody in retinal ischemia-reperfusion injury., CurrEye Res, 36, 1037-1046, 2011
  104. Efficacy and safety of switching from topical latanoprost to bimatoprost in patients with normal-tension glaucoma., J Ocul Pharmacol Ther, 27, 499-502, 2011
  105. Comparison of retinal nerve fiber layer thickness measurements using time domain and spectral domain optical coherence tomography, and visual field sensitivity., J Glaucoma, 20, 383-387, 2011
  106. D-allose as ischemic retina injury inhibitor during rabbit vitrectomy., Jpn J Ophthalmol, 55, 294-300, 2011
  107. Success rates of trabeculotomy for steroid-induced glaucoma: a comparative, multicenter, retrospective cohort study., Am J Ophthalmol, 151, 1047-1056, 2011
  108. Anti-oxidative effects of d-allose, a rare sugar, on ischemia-reperfusion damage following focal cerebral ischemia in rat., Neurosci Lett, 487, 103-106, 2011
  109. Comparison of ICare rebound tonometer with noncontact tonometer in healthy children., J Glaucoma, 20, 63-66, 2011
  110. Neuroprotection against retinal ischemia-reperfusion injury by blocking the angiotensin II type 1 receptor., Invest Ophthalmol Vis Sci, 51, 3629-3638, 2010
  111. Vascular endothelial growth factor concentrations in aqueous humor before and after subconjunctival injection of bevacizumab for neovascular glaucoma., Jpn J Ophthalmol, 54, 242-244, 2010
  112. Correlation between optical coherence tomography scan and histological specimen of a filtering bleb., Acta Ophthalmol, 88, 50-51, 2010
  113. Stratus optical coherence tomography study of filtering blebs after primary trabeculectomy with a fornix-based conjunctival flap., Acta Ophthalmol, 88, 60-64, 2010
  114. Effect of trabeculectomy on intraocular pressure fluctuation with postural change in eyes with open-angle glaucoma., J Glaucoma, 108, 689-691, 2009
  115. Neuroprotective effects of angiotensin II type 1 receptor blocker in a rat model of chronic glaucoma., Invest Ophthalmol Vis Sci, 50, 5800-5804, 2009
  116. Pharmacokinetics of bevacizumab after topical, subconjunctival, and intravitreal administration in rabbits., Invest Ophthalmol Vis Sci, Ⅾ, 4807-4813, 2009
  117. Risk factors for developing avascular filtering bleb after fornix-based trabeculectomy with mitomycin C., J Glaucoma, 18, 301-304, 2009
  118. Plateau iris syndrome associated with cysts and nocturnal elevation of intraocular pressure., Can J Ophthalmol, 43, 725, 2008
  119. Macular edema associated with latanoprost use in a patient with idiopathic juxtafoveal retinal telangiectasis., Jpn J Ophthalmol, 52, 68-70, 2008
  120. Both amacrine and bipolar cells release glutamate in the rat retina after ischemia /reperfusion insult in vitro., Curr Eye Res, 33, 782-788, 2008
  121. 3CB2, a marker of radial glia, expression after experimental intracerebral hemorrhage: role of thrombin., Brain Res, 1226, 156-162, 2008
  122. Correlation between retinal nerve fiber layer thickness and retinal sensitivity., Acta Ophthalmol, 86, 609-613, 2008
  123. Intraocular pressure elevation after injection of triamcinolone acetonide: a multicenter retrospective case-control study., Am J Ophthalmol, 145, 676-681, 2008
  124. Prevention of visual field defect progression with angiotensin-converting enzyme inhibitor in eyes with normal-tension glaucoma., Am J Ophthalmol, 142, 523-525, 2006
  125. Risk factors for elevated intraocular pressure after trans-tenon retrobulbar injections of triamcinolone., Jpn J Ophthalmol, 50, 235-238, 2006
  126. Neuroprotective effects of D-allose against retinal ischemia-reperfusion injury., Invest Ophthalmol Vis Sci, 47, 1653-1657, 2006
  127. The Ginkgo biloba extract (EGb 761) provides a neuroprotective effect on retinal ganglion cells in a rat model of chronic glaucoma., Curr Eye Res, 28, 153-157, 2004
  128. Relationship between postural change of the intraocular pressure and visual field loss in primary open-angle glaucoma., J Glaucoma, 12, 379-382, 2003
  129. Bradykinin sensitivity in primary open-angle glaucoma and normal-tension glaucoma patients., Am J Ophthalmol, 134, 922-924, 2002
  130. T-type calcium channel α1G and α1H subunits in human retinoblastoma cells and their loss after differentiation., J Neurophysiol, 88, 196-205, 2002
  131. Suppressive actions of betaxolol on ionic currents in retinal ganglion cells may explain its neuroprotective effects., Exp Eye Res, 70, 611-621, 2000
  132. Calcium channel activation facilitated by nitric oxide in retinal ganglion cells., J Neurophysiol,, 83, 198-206, 2000
  133. ★, Reticalmin: a novel calcium/calmodulin-dependent protein kinase IV-like protein in rat retina., Vision Res, 37, 2029-2033, 1997
  134. Developmental alternation of the expression and kinase activity of cylclin-dependent kinase 5 (Cdk5)/p35nck5a in the rat retina., J Neurochem, 67, 2478-2483, 1996
  135. Prevalence, characteristics, and pathogenesis of paravascular inner retinal defects associated with epiretinal membranes., Graefes Arch for Clin Exp Ophthalmol

Publications such as books

  1. 2018, J Ophthalmol, The management of glaucoma: structure and function., 2018, 2018, Scholarly Book, Joint work, 英語, Hirooka K, Higashide T and Jeoung JW

Invited Lecture, Oral Presentation, Poster Presentation

  1. Risk factors for postoperative hypotony after PreserFlo MicroShunt implantation, Hirooka K, Takeda M, Okada N, Baba T, Sakaguchi H, WGC2025, 2025/06/25, Without Invitation, English, World Glaucoma Association, Honolulu, Hawaii
  2. One - year outcomes of Preserflo MicroShunt surgery and trabeculectomy in Japanese patients with glaucoma, Shibata S, Okumichi H, Onoe H, Hirooka K, Sakaguchi H, WGC2025, 2025/06/25, Without Invitation, English, World Glaucoma Association, Honolulu, Hawaii
  3. One-Year Efficacy and Safety of Novel Minimally Invasive Glaucoma Surgery Using the Diamond Dusted Sweeper, Tokumo K, Yokoyama M, Kiuchi Y, Nikaido T, Baba T, Edo A, Okada N, Komatsu K, Okumichi H, Mochizuki H, Miyoshi T, Hirooka K, Sakaguchi H, WGC2025, 2025/06/25, Without Invitation, English, World Glaucoma Association, Honolulu, Hawaii
  4. The Neuroprotective Role of IGFBP-5 in Retinal Ganglion Cells Under Oxidative Stress: Mechanisms and Therapeutic Implications, Ko JA, Minamoto A, Komatsu K, Hirooka K, Sakaguchi H, ARVO 2025, 2025/05/08, Without Invitation, English, The Association for Research in Vision and Ophthalmology, Salt Lake City, Utah
  5. Changes in Corneal Higher-Order Aberrations Following Preserflo MicroShunt Implantation, Hirooka K, Baba T, Okada N, Nikaido T, Sakaguchi H, ARVO 2025, 2025/05/07, Without Invitation, English, The Association for Research in Vision and Ophthalmology, Salt Lake City, Utah
  6. Short-term outcomes of needle revision after PreserFlo Microshunt implantation in Japanese patients., Okada N, Hirooka K, Baba T, Tokumo K, Okumichi H, Kiuchi Y, Sakaguchi H, ARVO 2025, 2025/05/07, Without Invitation, English, The Association for Research in Vision and Ophthalmology, Salt Lake City, Utah
  7. Association of Tube Stabilizing Suture with Early Postoperative Hypotony in PreserFlo MicroShunt implantation, Tokumo K, Baba T, Ono A, Takeda M, Nikaido T, Okada N, Okumichi H, Kiuchi Y, Hirooka K, Sakaguchi H, ANZGS 2025, 2025/02/14, Without Invitation, English, Australian and New Zealand Glaucoma Society, Perth, Australia
  8. IGFBP-5 as a Critical Factor in Retinal Ganglion Cell Survival: Exploring Its Role in Oxidative Stress and Therapeutic Implications, Mizukami M, Ko JA, Minamoto A, Hirooka K, Kiuchi Y, Cell Bio 2024, 2024/12/17, Without Invitation, English, AN INTERNATIONAL FORUM FOR CELL BIOLOG, San Diego, California
  9. The Role of Nerve Growth Factor Secreted by Glial Cells in Protecting Retinal Ganglion Cells from Oxidative Stress: Analysis Using a 3D Co-Culture System, Ko JA, Minamoto A, Komatsu K, Hirooka K, Kiuchi Y, Cell Bio 2024, 2024/12/16, Without Invitation, English, AN INTERNATIONAL FORUM FOR CELL BIOLOG, San Diego, California
  10. PreserFlo MicroShunt Implantation under the Assistance of Ultrasound Biomicroscopy in a Patient with Congenital Glaucoma and Corneal Opacity, Ono A, Okada N, Baba T, Edo A, Tokumo K, Okumichi H, Hirooka K, Kiuchi Y, KGS2024, 2024/11/23, Without Invitation, English, The Korean Glaucoma Society, Seoul,South Korea
  11. Incidence of Ciliochoroidal Detachment Following iStent inject® W Implantation, Okada N, Hirooka K, Shibata S, Baba T, Onoe H, Tokumo K, Okumichi H, Kiuchi Y, KGS2024, 2024/11/23, Without Invitation, English, The Korean Glaucoma Society, Seoul,South Korea
  12. Prevalence of NTG in Patients With Primary Aldosteronism, Hirooka K, Higashide T, Sakaguchi K, Udagawa S, Sugiyama K, Kiuchi Y, AAO 2024, 2024/10/18, Without Invitation, English, American Academy of Ophthalmology, Chicago
  13. Risk factors for transient ciliochoroidal detachment after goniotomy with the Kahook Dual Blade, Hirooka K, Miyako F, Onoe H, Kiuchi Y, EGS2024, 2024/06/03, Without Invitation, English, European Glaucoma Society, Dublin,Ireland
  14. NGF Inhibition in Glial Cells Confirms Neuroprotective Role in RGC Co-Culture, Ko JA, Minamoto A, Hirooka K, Kiuchi Y, EGS2024, 2024/06/02, Without Invitation, English, European Glaucoma Society, Dublin,Ireland
  15. Surgical outcomes of ab interno trabeculotomy without phacoemulsification, Hirooka K, Mochizuki T, Okada N, Onoe H, Tokumo K, Okumichi H, Kiuchi Y, ARVO 2024, 2024/05/06, Without Invitation, English, The Association for Research in Vision and Ophthalmology, Seattle, Wash
  16. Corneal thickness of congenital cataract, Yoshitomi S, Kiuchi Y, Komatsu K, Hirooka K, ARVO 2024, 2024/05/05, Without Invitation, English, The Association for Research in Vision and Ophthalmology, Seattle, Wash
  17. Functional analysis of glia cells in retinal ganglion cells using coculture system, Ko JA, Minamoto A, Okumichi H, Hirooka K, Kiuchi Y, Cell Bio 2023, 2023/12/03, Without Invitation, English, The American Society for Cell Biology, Boston, MA
  18. Vision-related quality of life following combined cataract and minimally invasive glaucoma surgery or cataract surgery alone in glaucoma patients, Hirooka K, Yuasa Y, Okada N, Onoe H, Okumichi H, Kiuchi Y, WGC 2023, 2023/06/28, Without Invitation, English, World Glaucoma Association, ROME,ITALY
  19. Recurrent aqueous humor leaks after trabeculectomy, Murata K, Kouno S, Baba T, Okada N, Edo A, Mochizuki T, Onoe H, Tokumo K, Okumichi H, Hirooka K, Kiuchi Y, Case Discussion Glaucoma, 2023/06/18, With Invitation, English, Universitas Hasanuddin, Online
  20. Functional Analysis of Glia Cells in RGC using Coculture System, Ko JA, Minamoto A, Okumichi H, Hirooka K, Kiuchi Y, ARVO2023, 2023/04/24, Without Invitation, English, The Association for Research in Vision and Ophthalmology, New Orleans, America
  21. Blood flow in the optic nerve head in patients with primary aldosteronism, Hirooka K, Oki K, Ogawa-Ochiai K, Onoe H, Kiuchi Y, ARVO2023, 2023/04/24, Without Invitation, English, The Association for Research in Vision and Ophthalmology, New Orleans, America
  22. Retinal ganglion cell death in experimental aldosterone hypertension rat, Onoe H, Hirooka K, Kiuchi Y, ARVO2023, 2023/04/23, Without Invitation, English, The Association for Research in Vision and Ophthalmology, New Orleans, America
  23. Glaucoma secondary to Sturge-Weber syndrome, Kiuchi Y, Okada N, Hirooka K, Onoe H, Okumichi H, Tokumo K, APAO2023, 2023/02/26, With Invitation, English, Asia-Pacific Academy of Ophthalmology, Kuala Lumpur, Malaysia
  24. Functional Analysis of Glia Cells in RGC using coculuture system, Komatsu K, Ko JA, Minamoto A, Okumichi H, Hirooka K, Kiuchi Y, ISER2023, 2023/02/19, Without Invitation, English, International Society for Eye Research, Gold Coast, Queensland, Australia
  25. Comparison of long-term outcomes between microhook ab interno trabeculotomy and goniotomy with the Kahook Dual Blade., Hirooka K, Okada N, Onoe H, Okumichi H, Kiuchi Y, The American Academy of Ophthalmology's annual meeting 2022, 2022/09/30, Without Invitation, English, AAO, Chicago,America
  26. Transient ciliochoroidal detachment after microhook ab interno trabeculotomy., Hirooka K, Miyako F, Onoe H, Okada N, Okumichi H, Kiuchi Y, 15th EGS Congress, 2022/06/07, Without Invitation, English, European Glaucoma Society, Athens Greece
  27. Frequency and predictors of glaucoma after congenital cataract surgery, Yoshitomi S, Hirooka K, Onoe H, Sakata H, Murakami Y, Okumichi H, Kiuchi Y, WGC2021, 2021/06/30, Without Invitation, English, World Glaucoma Association, Virtual
  28. Lower eyelid epiblepharon associated with childhood glaucoma., Aikawa K, Sueoka K, Komatsu K, Sakata H, Murakami Y, Okumichi H, Hirooka K, Kiuchi Y, WGC2021, 2021/06/30, Without Invitation, English, World Glaucoma Association, Virtual
  29. The efficacy of bleb needle revision with mitomycin C for failed blebs after trabeculectomy., Okada N, Hirooka K, Onoe H, Tokumo K, Murakami Y, Okumichi H, Kiuchi Y, WGC2021, 2021/06/30, Without Invitation, English, World Glaucoma Association, Virtual
  30. The effect of ripasudil on bleb formation after trabeculectomy - multicenter randomized study., Onoe H, Okumichi H, Hirooka K, Nitta E, Baba T, Tanito M, Matsuoka Y, Nakakura S, Kiuchi Y, WGC2021, 2021/06/30, Without Invitation, English, World Glaucoma Association, Virtual
  31. Treatment Results Before and After Switching from Prostaglandin Analogues to Omidenepag Isopropyl., Tokumo K, Taniyama Y, Hiyama T, Onoe H, Sakata H, Murakami Y, Okumichi H, Hirooka K, Kiuchi Y, WGC2021, 2021/06/30, Without Invitation, English, World Glaucoma Association, Virtual
  32. A slight conjunctival laceration near the implant causes postoperative infection, Aikawa K, Kinouchi R, Taniyama Y, Onoe H, Sakata H, Tokumo K, Murakami Y, Iwabe R, Okumichi H,Hirooka K, Kiuchi Y, The 31st Meeting of Japan Glaucoma Society, 2020/10/02, Without Invitation, Japanese, Japan Glaucoma Society, oita(VIRTUAL)
  33. Higher order aberration after ab interno trabeculotomy, Onoe H, Hirooka K, Okumichi H, Iwabe R, Murakami Y, Kiuchi Y, The 31st Meeting of Japan Glaucoma Society, 2020/10/02, Without Invitation, Japanese, Japan Glaucoma Society, oita(VIRTUAL)
  34. Vision-related quality of life following glaucoma surgery, K Hirooka, The 31st Meeting of Japan Glaucoma Society, 2020/10/02, With Invitation, Japanese, Japan Glaucoma Society, oita(VIRTUAL)
  35. Long-term effect of trabeculectomy on corneal endothelial cell loss., Hirooka K, Nitta E, Ukegawa K, Sato S, Kiuchi Y, ARVO 2019 Annual Meeting, 2019/04/30, Without Invitation, English, The Association for Research in Vision and Ophthalmology, VANCOUVER
  36. PERIPAPILLARY AND MACULAR CHOROIDAL AREA IN PATIENTS WITH NORMAL-TENSION GLAUCOMA, Hirooka K, Kojima H, Nitta E, Kiuchi Y, 8th World Glaucoma Congress, 2019/03/28, Without Invitation, English, World Glaucoma Association, melbourne
  37. Changes in Corneal Endothelial Cells after Trabeculectomy and EX-PRESS Shunt: 2-Year Follow-up., Hirooka K, World Ophthalmology Congress 2018, 2018, Without Invitation, English
  38. Changes in choroidal area after intraocular pressure reduction following trabeculectomy., Hirooka K, Hirooka K, Kojima H, Nitta E, Ukegawa K, Sonoda S, Sakamoto T., The Association for Research in Vision and Ophthalmology 2018, 2018, Without Invitation, English
  39. The relationship between the renin-angiotensin–aldosterone system and NMDA receptor-mediated signal and the prevention of retinal ganglion cell death., Hirooka K, Kobayashi M, Ono A, Nakano Y, Tsujikawa A., World Glaucoma Council 2017, 2017, Without Invitation, English
  40. Oxygen saturation of the retinal vessels may differ between primary open-angle glaucoma and normal-tension glaucoma., Hirooka K, Shimazaki T, Nakano Y, Nitta E, Ukegawa K, Tsujikawa A., The Association for Research in Vision and Ophthalmology 2017, 2017, Without Invitation, English
  41. Vision-related quality of life following glaucoma filtration surgery., Hirooka K, Nitta E, Ukegawa K, Tsujikawa A., America Academy of Ophthalmology, 2016, Without Invitation, English
  42. Comparison of visual acuity and corneal higher-order aberrations after EX-PRESS or trabeculectomy, and the determination of associated factors that influence visual function., Hirooka K, Kobayashi N, Nitta E, Ukegawa K, Tsujikawa A., European Glaucoma Society, 2016, Without Invitation, English
  43. Relationship between oxygen saturation of the retinal vessels and visual field defect in glaucoma patients: comparison with each hemifield., Hirooka K, Shimazaki T, Nakano Y, Nitta E, Ukegawa K, Sato S, Tsujikawa A., The Association for Research in Vision and Ophthalmology, 2016, Without Invitation, English
  44. Comparison of Macular Integrity Assessment (MAIA), MP-3, and Humphrey Field Analyzer instruments in evaluating the structure-function relationship in the macula., Hirooka K, Misaki K, Nitta E, Ukegawa K, Sato S, Tsujikawa A., American Academy of Ophthalmology, 2015, Without Invitation, English
  45. Reconstruction of a nonfunctional trabeculectomy bleb with mitomycin C: prognostic factors for surgical failure., Hirooka K, Nitta E, Ukegawa K, Sato S, Tsujikawa A., World Glaucoma Council, 2015, Without Invitation, English
  46. Estimating the rate of retinal ganglion cell loss to detect glaucoma progression., Hirooka K, Izumibata S, Manabe S, Ukegawa K, Nitta E, Sato S, Tsujikawa A., The Association for Research in Vision and Ophthalmology, 2015, Without Invitation, English
  47. The relationship between quality of vision and visual field loss in glaucoma patients., Hirooka K, Nitta E, Sato S, Tsujikawa A., American Academy of Ophthalmology, 2014, Without Invitation, English
  48. reoperative intravitreal bevacizumab on trabeculectomy with mitomycin C for neovascular glaucoma: prognostic factor for surgical failure., Hirooka K, Baba T, Nitta E, Tenkumo K, Sato S., European Glaucoma Society, 2014, Without Invitation, English
  49. Preoperative intravitreal bevacizumab on trabeculectomy with mitomycin C for neovascular glaucoma: prognostic factor for surgical failure., Hirooka K, Baba T, Nitta E, Tenkumo K, Sato S., The Association for Research in Vision and Ophthalmology, 2014, Without Invitation, English

Awards

  1. 2014, American Academy of Ophthalmology “Best Poster” Award

Social Activities

History as Peer Reviews of Academic Papers

  1. 2016, Acta Ophthalmologica, Editor
  2. 2016, Journal of ophthalmology, Chief editor