広島大学

Basic Information

Academic Degrees

• Kyushu Dental College

Educational Activity

Course in Charge

1. 2024, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
2. 2024, Undergraduate Education, 3Term, Operative Dentistry I
3. 2024, Undergraduate Education, 4Term, Operative Dentistry II
4. 2024, Undergraduate Education, 1Term, Basic Practice of Endodontics and Operative Dentistry I
5. 2024, Undergraduate Education, 2Term, Basic Practice of Endodontics and Operative Dentistry II
6. 2024, Undergraduate Education, First Semester, Dental Research Practices I
7. 2024, Undergraduate Education, Second Semester, Dental Research Practices II
8. 2024, Undergraduate Education, 2Term, Advanced Course in Functional and Regenerative Oral Medicine
9. 2024, Undergraduate Education, 2Term, General Seminar on Clinical Dentistry
10. 2024, Undergraduate Education, Academic Year, Clinical Practice (Endodontics and Operative Dentistry)
11. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Biological Endodontics
12. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Biological Endodontics
13. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Biological Endodontics
14. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Biological Endodontics

Research Activities

Academic Papers

1. Inhibition of BMP2-induced bone formation by the p65 subunit of NF-kB via an interaction with Smad4., Molecular Endocrinology, 28(9), 1460-1470, 2014
2. Low-level laser irradiation enhances BMP-induced osteoblast differentiation by stimulating the BMP/Smad signaling pathway., Journal of Cellular Biochemistry, 111, 1445-1452, 2010
3. The Novel NF-kB Inhibitor, MTI-II Peptide Anti-Inflammatory Drug, Suppresses Inflammatory Responses in Odontoblast-Like Cells, Journal of Cellular Biochemistry, 117, 2552-2558, 201604
4. Fine-tuning between BMP and NF-kB pathways regulates osteoblastic bone formation., Journal of Oral Biosciences, 73-77, 2016
   Link to Paper Search Results by DOI
5. A Small Nuclear Acidic Protein (MTI-II, Zn2+ Binding Protein, Parathymosin) That Inhibits Transcriptional Activity of NF-kappa B and Its Potential Application to Antiinflammatory Drugs, Endocrinology, 157(12), 4973-4986, 2016
   Link to Paper Search Results by DOI
6. Two-year clinical comparison of a flowable-type nano-hybrid composite and a paste-type composite in posterior restoration, Journal of Investigative and Clinical Dentistry, 8(3), 1-5, 201708
7. Effects of 4-META/MMA-TBB Resin at Different Curing Stages on Osteoblasts and Gingival Epithelial Cells, The Journal of Adhesive Dentistry, 18(2), 111-118, 2016
8. Inhibition of bone morphogenetic protein-induced osteoblast differentiation, Journal of Oral Biosciences, 57(4), 179-184, 2015
9. A peptide that blocks the interaction of NF-B p65 subunit with Smad4 enhances BMP2-induced osteogenesis, JOURNAL OF CELLULAR PHYSIOLOGY, 233(9), 7356-7366, 201809
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10. The current and future therapies of bone regeneration to repair bone defects, International Journal of Dentistry, 2012
11. Regeneration approaches for dental pulp and periapical tissues with growth factors, biomaterials, and laser irradiation, Polymers, 2011
12. Lactacystin, a proteasome inhibitor, enhances BMP-induced osteoblastic differentiation by increasing active Smads, Biochemical and Biophysical Research Communications, 2011
13. Molecular mechanisms of BMP-induced bone formation: Cross-talk between BMP and NF-κB signaling pathways in osteoblastogenesis, Japanese Dental Science Review, 2010
14. Dental pulp cell-derived powerful inducer of TNF-alpha comprises PKR containing stress granule rich microvesicles, SCIENTIFIC REPORTS, 9, 20190307
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15. Heparin–LL37 complexes are less cytotoxic for human dental pulp cells and have undiminished antimicrobial and LPS-neutralizing abilities, International Endodontic Journal, 52(9), 1327-1343, 2019
16. A small nuclear acidic protein (MTI-II, Zn2+-binding protein, parathymosin) attenuates TNF-alpha inhibition of BMP-induced osteogenesis by enhancing accessibility of the Smad4-NF-kappa B p65 complex to Smad binding element, MOLECULAR AND CELLULAR BIOCHEMISTRY, 469(1-2), 133-142, 202006
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17. Surgical sealing of laterally localized accessory root canal with resin containing S-PRG filler in combination with non-surgical endodontic treatment: A case report, Dentistry Journal, 8(4), 202011
18. Concordance study between regular face-to-face dental diagnosis and dental telediagnosis using fluorescence, JOURNAL OF TELEMEDICINE AND TELECARE, 27(8), 509-517, 202109
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