MIZUKI HONDA

Last Updated :2025/01/07

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Assistant Professor
E-mail
mizuki5zhiroshima-u.ac.jp
Self-introduction
I'm working on developing a novel spatial omics technology called Photo Isolation Chemistry (PIC), which enables us to isolate omics data from UV-irradiated areas within tissue sections. Concurrently, I am conducting research utilizing a data-driven multilayered analysis approach with PIC to elucidate the mechanisms of stress-induced neuropsychiatric disorders during brain development, aging, and the aging process.

Basic Information

Major Professional Backgrounds

  • 2020/04/01, 2024/03/31, Kyoto University, Graduate School of Medicine, Medical Innovation Center, Program-Specific Assistant Professor
  • 2018/10/01, 2020/03/31, Kyushu University, Department of Developmental Biology, Graduate School of Medical Sciences, Assistant Professor
  • 2018/04/01, 2018/09/30, Kyushu University, Department of Developmental Biology, Graduate School of Medical Sciences, Research Fellow

Educational Backgrounds

  • Kyushu University, Graduate School of Medical Sciences, Japan, 2014/04/01, 2018/03/20
  • Kyushu University, Graduate School of Medical Sciences, Japan, 2013/04/01, 2014/03/25
  • Nara Institute of Science and Technology, Division of Biological Science, Japan, 2012/04/01, 2013/03/31
  • Kindai University, Department of Genetic Engineering, Japan, 2008/04/01, 2012/03/21

Academic Degrees

  • Kyushu University
  • Kyushu University

Affiliated Academic Societies

  • The Japan Neuroscience Society
  • The Society for Biotechnology, Japan
  • Japan Bioindustry Association
  • Japanese Society of Developmental Biology
  • The Molecular Biology Society of Japan

Educational Activity

Course in Charge

  1. 2024, Liberal Arts Education Program1, 2Term, Introductory Seminar for First-Year Students
  2. 2024, Undergraduate Education, 1Term, Seminar on Biological Science
  3. 2024, Undergraduate Education, 2Term, Animal Physiology B
  4. 2024, Undergraduate Education, Second Semester, Seminar for Molecular Physiology
  5. 2024, Undergraduate Education, Second Semester, Practice for Fundamental Biology II
  6. 2024, Undergraduate Education, Second Semester, Practice for Fundamental Biology IV
  7. 2024, Graduate Education (Doctoral Program) , 1Term, Research Plans in Life Science
  8. 2024, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Basic Biology
  9. 2024, Graduate Education (Master's Program) , First Semester, Exercises in Basic Biology A
  10. 2024, Graduate Education (Master's Program) , Second Semester, Exercises in Basic Biology B
  11. 2024, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences
  12. 2024, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar A
  13. 2024, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar B
  14. 2024, Graduate Education (Master's Program) , 3Term, Introduction to Disease Models
  15. 2024, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biomedial Science
  16. 2024, Graduate Education (Master's Program) , First Semester, Exercises in Biomedical Science A
  17. 2024, Graduate Education (Master's Program) , Second Semester, Exercises in Biomedical Science B
  18. 2024, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar C
  19. 2024, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences
  20. 2024, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar D
  21. 2024, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar E

Research Activities

Academic Papers

  1. Biallelic null variants in PNPLA8 cause microcephaly by reducing the number of basal radial glia, Brain, 20240731
    Link to Paper Search Results by DOI
  2. ★, Photo-isolation chemistry for high-resolution and deep spatial transcriptome with mouse tissue sections, STAR Protocols, 3(2), 20220617
    Link to Paper Search Results by DOI
  3. Neural stem/precursor cells dynamically change their epigenetic landscape to differentially respond to BMP signaling for fate switching during brain development, Genes & Development, 35(21-22), 1431-1444, 20211101
    Link to Paper Search Results by DOI
  4. ★, High-depth spatial transcriptome analysis by photo-isolation chemistry, Nature Communications, 20210720
    Link to Paper Search Results by DOI
  5. ★, PRMT1 regulates astrocytic differentiation of embryonic neural stem/precursor cells, Journal of Neurochemistry, 142(6), 901-907, 20170711
    Link to Paper Search Results by DOI

Publications such as books

  1. Results and Problems in Cell Differentiation, Epigenetic Regulation of Human Neural Stem Cell Differentiation., Springer, 2018, Scholarly Book, Joint work, English, Mizuki Honda, Sayako Katada, Kinichi Nakashima

Invited Lecture, Oral Presentation, Poster Presentation

  1. Development and Application of the High-Resolution Spatial Transcriptome Method Photo-Isolation Chemistry (PIC), Mizuki Honda, 2024/11/27, With Invitation, Japanese, The 47th Annual Meeting of the Molecular Biology Society of Japan, Fukuoka
  2. High-depth Spatial Regulomics Considering Microstructure, Mizuki Honda, The 95th Meeting of The Zoological Society of Japan in Nagasaki, 2024/09/12, With Invitation, Japanese, Nagasaki
  3. High-Depth Spatial Analysis of Gene Expression in Tissues Using Photo-Isolation Chemistry, Mizuki Honda, Okayama University, Graduate School of Environmental and Life Science, 472nd Biological Sciences Seminar, 2024/08/07, With Invitation, Japanese, Okayama University
  4. High-Resolution and High-Depth Spatial Transcriptome Profiling in Microstructures, Mizuki Honda, The 51st Annual Meeting of the Japanese Society of Toxicology, 2024/07/04, With Invitation, Japanese, Fukuoka
  5. High-Resolution and High-Depth Spatial Transcriptome Profiling in Microstructures, Mizuki Honda, The 67th Annual Meeting of the Japanese Society of Nephrology, 2024/06/29, With Invitation, Japanese, Yokohama
  6. Development of a Novel Spatial Omics Technology by Integrating Optics and Chemistry, Mizuki Honda, The 18th Annual Meeting of Japanese Society for Chemical Biology, 2024/05/29, With Invitation, Japanese, Tokyo
  7. High-Resolution Spatial Analysis of Gene Expression within Tissues Using Photo-Isolation Chemistry, Mizuki Honda, 29th Biotechnology Colloquium, 2024/05/23, With Invitation, Japanese, The Society for Biotechnology, Research Innovation Center, Waseda University
  8. High-resolution and High-depth Spatial Transcriptomics Based on Microstructure, Mizuki Honda, ASHBi SignAC Workshop: High-content epigenome analysis in the next phase, 2024/05/15, With Invitation, English, ASHBi, Kyoto University, Kyoto