Tadashi Shimamoto
Last Updated :2021/02/02
- Affiliations, Positions
- Graduate School of Integrated Sciences for Life, Professor
- E-mail
- tadashis
hiroshima-u.ac.jp
Basic Information
Academic Degrees
- Doctor of Philosophy, Okayama University
- Master of Pharmaceutical Science, Okayama University
Research Fields
- Agricultural sciences;Animal life science;Veterinary medical science
- Medicine,dentistry, and pharmacy;Basic medicine;Bacteriology (including mycology)
Research Keywords
- DNA aptamer|Norovirus
- pathogenic bacteria|drug resistance
- SRSV
- pathogenic bacteria
- reverse transcriptase
- retron
- Caco-2
- integron
- antisense DNA
- reverse transcriptase
Educational Activity
Course in Charge
- 2020, Liberal Arts Education Program1, 1Term, Life, food, and environmental sciences
- 2020, Liberal Arts Education Program1, 2Term, Life, food, and environmental sciences
- 2020, Liberal Arts Education Program1, 3Term, Food safety and health science
- 2020, Undergraduate Education, 1Term, Introduction to Applied Biological Sciences
- 2020, Undergraduate Education, Intensive, Laboratory Work in General Biology I
- 2020, Undergraduate Education, 2Term, Reading of Foreign Literature
- 2020, Undergraduate Education, 2Term, Introduction to Applied Biological Science I
- 2020, Undergraduate Education, Intensive, Laboratory Work in Food Hygiene
- 2020, Undergraduate Education, 2Term, Introduction to Microbiology
- 2020, Undergraduate Education, 3Term, Public Health
- 2020, Undergraduate Education, Academic Year, Graduation Thesis
- 2020, Undergraduate Education, 1Term, Food Microbiology
- 2020, Undergraduate Education, 3Term, Modern Food Science
- 2020, Undergraduate Education, Intensive, (AIMS) Modern Food Science
- 2020, Graduate Education (Master's Program) , First Semester, Research for Academic Degree Dissertation
- 2020, Graduate Education (Doctoral Program) , First Semester, Exercises in Food Science and Biofunctions (B)
- 2020, Graduate Education (Doctoral Program) , Second Semester, Exercises in Food Science and Biofunctions (B)
- 2020, Graduate Education (Master's Program) , 3Term, foodborne pathogenic genetics
- 2020, Graduate Education (Master's Program) , 4Term, exercises in foodborne pathogenic genetics
- 2020, Graduate Education (Master's Program) , 1Term, Exercises in Food andAgriLife Science A
- 2020, Graduate Education (Master's Program) , 2Term, Exercises in Food andAgriLife Science A
- 2020, Graduate Education (Master's Program) , 3Term, Exercises in Food andAgriLife Science B
- 2020, Graduate Education (Master's Program) , 4Term, Exercises in Food andAgriLife Science B
- 2020, Graduate Education (Master's Program) , 1Term, Microbiology for Food Safety I
- 2020, Graduate Education (Master's Program) , 3Term, Microbiology for Food Safety II
- 2020, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences
- 2020, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences
Research Activities
Academic Papers
- Purification and analysis of the structure of α-galactosidase from Escherichia coli, Biochemical and Biophysical Research Communications, 151(1), 236-241, 19880201
- Characterization of a novel L-serine transport system in Escherichia coli, JOURNAL OF BACTERIOLOGY, 170(5), 2236-2239, 19880501
- Amino acid substitutions and alteration in cation specificity in the melibiose carrier of Escherichia coli, Journal of Biological Chemistry, 263(28), 14276-14280, 19881001
- Genetic characterization of multidrug resistance in Shigella spp. from Japan, Journal of Medical Microbiology, 55(12), 1685-1691, 20061201
- Proteus mirabilis clinical isolate harboring a new variant of Salmonella genomic island 1 containing the multiple antibiotic resistance region, Journal of Antimicrobial Chemotherapy, 59(2), 184-190, 20070201
- Zoo animals as resorvoirs of gram-negative bacteria harboring integrons and antimicrobial resistance genes, Applied and Environmental Microbiology, 73(20), 6686-6690, 20071015
- Emergence of a cefepime- and cefpirome-resistant Citrobacter freundii clinical isolate harbouring a novel chromosomally encoded AmpC β-lactamase, CMY-37, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 32(3), 256-261, 20080901
- Molecular characterization of multidrug-resistant avian pathogenic Escherichia coli isolated from septicemic broilers, INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 303(8), 475-483, 20131201
- Isolation and molecular characterization of Salmonella enterica, Escherichia coli O157:H7 and Shigella spp. from meat and dairy products in Egypt, INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 168, 57-62, 20140103
- Genetic characterization of antibiotic resistance and virulence factors in Enterococcus spp. from Japanese retail ready-to-eat raw fish, FOOD MICROBIOLOGY, 38, 62-66, 20140401
- Genetic basis of multidrug resistance in Salmonella enterica serovars Enteritidis and Typhimurium isolated from diarrheic calves in Egypt, ACTA TROPICA, 111(2), 144-149, 20090801
- Isolation and molecular characterization of multidrug-resistant strains of Escherichia coli and Salmonella from retail chicken meat in Japan, JOURNAL OF FOOD SCIENCE, 74(7), M405-M410, 20090901
- Characterization of integrons and antimicrobial resistance genes in clinical isolates of Gram-negative bacteria from Palestinian hospitals, MICROBIOLOGY AND IMMUNOLOGY, 53(11), 595-602, 20091101
- ★, Nucleotide sequence of the melB gene and characteristics of deduced amino acid sequence of the melibiose carrier in Escherichia coli, The Journal of Biological Chemistry, 259(7), 4320-4326, 19840401
- Nucleotide sequence of the promoter region of the melibiose operon of Escherichia coli, Biochemical and Biophysical Research Communications, 121(1), 41-46, 19840501
- Value of heptyl-β-D-thioglucoside, a new nonionic detergent, in studies on membrane proteins, Journal of Biochemistry, 97(6), 1807-1810, 19850601
- Properties of a Na+-coupled serine-threonine transport system in Escherichia coli, Biochimica et Biophysica Acta, 905(1), 231-239, 19870701
- Cloning and expression of the 5’-nucleotidase gene of Vibrio parahaemolyticus in Escherichia coli and overproduction of the enzyme, Journal of Biochemistry, 105(5), 841-846, 19890301
- Purification and characterization of membrane-bound 5’-nucleotidase of Vibrio parahaemolyticus, Journal of Biochemistry, 105(5), 785-789, 19890301
- Sequence analysis of nutA gene encoding membrane-bound Cl--dependent 5’-nucleotidase of Vibrio parahaemolyticus, Journal of Biochemistry, 109(1), 24-29, 19910101
- Cloning and nucleotide sequence of the gene (citA) encoding a citrate carrier from Salmonella typhimurium, Journal of Biochemistry, 110(1), 22-28, 19910701
- Cloning and nucleotide sequence of the gene (citC) encoding a citrate carrier from several Salmonella serovars, Journal of Biological Chemistry, 267(14), 9559-9564, 19920501
- ★, Reverse transcriptase from bacterial retrons require specific secondary structures at the 5’-end of the template for the cDNA priming reaction, Journal of Biological Chemistry, 268(4), 2684-2692, 19930201
- Transcriptional attenuation and differential mRNA stability in the regulation of the Escherichia coli melibiose operon, Journal of Biochemistry, 115(6), 1185-1189, 19940601
- ★, The formation of the 2’, 5’-phosphodiester linkage in the cDNA priming reaction by bacterial reverse transcriptase in a cell-free system, Journal of Biological Chemistry, 270(2), 581-588, 19950101
- The role of ribonuclease H in multicopy single-stranded DNA synthesis in retron-Ec73 and retron-Ec107 of Escherichia coli, JOURNAL OF BACTERIOLOGY, 177(1), 264-267, 19950101
- Mutational analysis of the CitA citrate transporter from Salmonella typhimurium: Altered substrate specificity, Biochemical and Biophysical Research Communications, 226(2), 481-487, 19960101
- Primary structure and properties of the Na+/glucose symporter (SglS) of Vibrio parahaemolyticus, JOURNAL OF BACTERIOLOGY, 179(5), 1805-1808, 19970301
- Inhibition of melibiose transporter by amiloride in Escherichia coli, Biochemical and Biophysical Research Communications, 233(1), 147-149, 19970601
- A melibiose transporter and an operon containing its gene in Enterobacter cloacae, JOURNAL OF BACTERIOLOGY, 179(13), 4443-4445, 19970701
- Characteristics of the melibiose transporter and its primary structure in Enterobacter aerogenes, Biochimica et Biophysica Acta, 1326(1), 83-91, 19970701
- Sequence of a melibiose transporter gene of Enterobacter cloacae, Biochimica et Biophysica Acta, 1354(1), 7-12, 19970901
- In vitro synthesis of multicopy single-stranded DNA, using separate primer and template RNAs, by Escherichia coli reverse transcriptase, JOURNAL OF BACTERIOLOGY, 180(11), 2999-3002, 19980601
- Conversion of temperature-sensitive to -resistant gene expresssion due to mutations in the promoter region of the melibiose operon in Escherichia coli, Journal of Biological Chemistry, 273(27), 16860-16864, 19980701
- ★, A retroelement in Vibrio cholerae, Molecular Microbiology, 34(3), 631-632, 19990201
- A cryptic melibiose transporter gene possessing a frameshift from Citrobacter freundii, JOURNAL OF BIOCHEMISTRY, 129(4), 607-613, 20010401
- msDNA-St85, a multicopy single-stranded DNA isolated from Salmonella enterica serovar Typhimurium LT2 with the genomic analysis of its retron, FEMS Microbiology Letters, 224(2), 291-297, 20030701
- New aminoglycoside acetyltransferase gene, aac(3)-Id, in a class 1 integron from a multiresistant strain of Vibrio fluvialis isolated from an infant aged 6 months, Journal of Antimicrobial Chemothrapy, 53(6), 947-951, 20040601
- A plasmid-encoded class 1 integron carrying sat, a putative phosphoserine phosphatase gene and aadA2 from enterotoxigenic Escherichia coli O159 isolated in Japan, FEMS Microbiology Letters, 235(2), 243-248, 20040601
- The first characterization of extended-spectrum β-lactamase-producing Salmonella in Japan, Journal of Antimicrobial Chemotherapy, 54(1), 283-284, 20040701
- Complex formation between a putative 66-residue thumb domain of bacterial reverse transcriptase RT-Ec86 and the primer recognition RNA, JOURNAL OF BIOLOGICAL CHEMISTRY, 279(49), 50735-50742, 20041203
- A variant type of Vibrio cholerae SXT element in a multidrug-resistant strain of Vibrio fluvialis, FEMS Microbiology Letters, 242(2), 241-247, 20050101
- ★, Molecular characterization of integrons in non-typhoid Salmonella serovars isolated in Japan: description of an unusual class 2 integron, Journal of Antimicrobial Chemotherapy, 55(3), 371-374, 20050301
- Molecular characterization of a multidrug-resistant strain of enteroinvasive Escherichia coli O164 isolated in Japan, Journal of Medical Microbiology, 54(3), 273-278, 20050301
- Characterization of a multidrug-resistant isolate of Salmonella Paratyphi B from Japan, Journal of Antimicrobial Chemotherapy, 56(1), 250-250A, 20050701
- Genomic analysis of a multidrug-resistant strain of enterohaemorrhagic Escherichia coli O157:H7 causing a family outbreak in Japan, Journal of Medical Microbiology, 54(9), 867-872, 20050901
- Class 2 integrons in Vibrio cholerae, Journal of Medical Microbiology, 55(5), 643-644, 20060501
- First characterization and Emergence of SHV-60 in raw milk of a healthy cow in Japan, JOURNAL OF VETERINARY MEDICAL SCIENCE, 70(11), 1269-1272, 20081101
- Molecular characterization of antimicrobial resistance in Salmonella isolated from animals in Japan, JOURNAL OF APPLIED MICROBIOLOGY, 106(2), 402-409, 20090201
- Prevalence and molecular characterization of ampicillin resistant Enterobacteriaceae isolated from traditional Egyptian Domiati cheese, JOURNAL OF FOOD PROTECTION, 72(3), 624-630, 20090301
- Genetic analysis of antimicrobial resistance in Escherichia coli isolated from diarrheic neonatal calves, VETERINARY MICROBIOLOGY, 136(42798), 397-402, 20090512
- Isolation and molecular characterization of multidrug-resistant Gram-negative bacteria from imported flamingos in Japan, ACTA VETERINARIA SCANDINAVICA, 51(1), 46, 20091124
- Molecular analysis of antimicrobial resistance in Gram-negative bacteria isolated from fish farms in Egypt, JOURNAL OF VETERINARY MEDICAL SCIENCE, 72(6), 727-734, 20100601
- Towards a compatible probiotic-antibiotic combination therapy: assessement of antimicrobial resistance in the Japanese probiotics, Journal of Applied Microbiology, 109(4), 1349-1360, 20101001
- Molecular characterization of antimicrobial resistance in Gram-negative bacteria isolated from bovine mastitis in Egypt, MICROBIOLOGY AND IMMUNOLOGY, 55(5), 318-327, 20110501
- Two novel retron elements are replaced with retron-Vc95 in Vibrio cholerae, MICROBIOLOGY AND IMMUNOLOGY, 55(7), 510-513, 20110701
- Asymptomatic intramammary infection with multidrug-resistant Gram-negative bacteria in a research dairy farm: Incidence and genetic basis of resistance, JOURNAL OF VETERINARY MEDICAL SCIENCE, 73(8), 1089-1092, 20110801
- Comparative study of different msDNA (multicopy single-stranded DNA) structures and phylogenetic comparison of reverse taranscriptases (RTs): evidence for vertical inheritance, Bioinformation, 7(4), 176-179, 20111014
- A novel msDNA (multi-copy single-stranded DNA) strain present in Yersinia frederiksenii ATCC 33641 cintig01029 enteropathogenic bacteria with the genomic analysis of its retron, Journal of Pathogens, 2011, 693769, 20111117
- Genetic analysis of multiple antimicrobial resistance in Salmonella isolated from diseased broilers in Egypt, MICROBIOLOGY AND IMMUNOLOGY, 56(4), 254-261, 20120401
- Occurrence and characteristics of methicillin-resistant and -susceptible Staphylococcus aureus and methicillin-resistant coagulase-negative staphylococci from Japanese retail ready-to-eat raw fish, INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 156(3), 286-289, 20120701
- A novel retron of Vibrio parahaemolyticus is closely related to retron-Vc95 of Vibrio cholerae, JOURNAL OF MICROBIOLOGY, 51(3), 323-328, 20130601
- Antiviral Effects of Persimmon Extract on Human Norovirus and Its Surrogate, Bacteriophage MS2, JOURNAL OF FOOD SCIENCE, 79(5), M941-M946, 20140501
- Characterization of integrons and resistance genes in multidrug-resistant Salmonella enterica isolated from meat and dairy products in Egypt, INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 189, 39-44, 20141017
- Molecular analysis of multidrug resistance in Shiga toxin-producing Escherichia coli O157:H7 isolated from meat and dairy products, INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 193, 68-73, 20150116
- Molecular characterization of multidrug-resistant Shigella spp. of food origin, INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 194, 78-82, 20150202
- Prevalence, antibiotic resistance and virulence of Enterococcus spp. in Egyptian fresh raw milk cheese, FOOD CONTROL, 50, 815-820, 20150401
- Antimicrobial effects of blueberry, raspberry, and strawberry aqueous extracts and their effects on virulence gene expression in Vibrio cholerae, PHYTOTHERAPY RESEARCH, 29(11), 1791-1797, 20151101
- Seafood as a reservoir of Gram-negative bacteria carrying integrons and antimicrobial resistance genes in Japan, Biomedical and Environmental Science, 28(12), 924-927, 20151201
- Emergence of plasmid-mediated colistin resistance gene mcr-1 in a clinical Escherichia coli isolate from Egypt, Antimicrobial Agents and Chemotherapy, 60(5), 3249-3250, 20160501
- Characterisation of the plasmid-mediated colistin resistance gene mcr-1 in Escherichia coli isolated from animals in Egypt, International Journal of Antimicrobial Agents, 47(5), 413-414, 20160501
- Emergence of an NDM-5-producing clinical Escherichia coli isolate in Egypt, INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 48, 46-48, 20160701
- NDM-4 and NDM-5-producing Klebsiella pneumoniae coinfection in a 6-month-old infant, Antimicrobial Agents and Chemotherapy, 60(7), 4416-4417, 20160701
- Emergence of a novel β-lactamase in food of animal origin: Characterisation of SHV-111, from a cheese isolate of Klebsiella pneumoniae with an amino acid substitution in a strictly conserved position (P174S) in the Ω-loop, Journal of Medical Microbiology, 66(1), 96-97, 20170101
- High carbapenem resistance in clinical Gram-negative pathogens isolated in Egypt, Microbial Drug Resistance, 23(7), 838-844, 20172001
- First report in Africa of two clinical isolates of Proteus mirabilis carrying Salmonella genomic island (SGI1) variants, SGI1-PmABB and SGI1-W, Infection, Genetics and Evolution, 51, 132-137, 20170701
- Molecular and Phenotypic Analysis of Hemolytic Aeromonas Strains Isolated from Food in Egypt Revealed Clinically Important Multidrug Resistance and Virulence Profiles, Journal of Food Protection, 81(6), 1015-1021, 20180601
- Molecular and Phenotypic Analysis of Hemolytic Aeromonas Strains Isolated from Food in Egypt Revealed Clinically Important Multidrug Resistance and Virulence Profiles, JOURNAL OF FOOD PROTECTION, 81(6), 1015-1021, 20180601
- Occurrence of Salmonella genomic island 1 (SGI1) in two African Proteus mirabilis strains isolated from diseased chicken flocks, INFECTION GENETICS AND EVOLUTION, 62, 8-10, 201808
- Emergence of Salmonella Genomic Island 1 Variant SGI1-W in a Clinical Isolate of Providencia stuartii form Egypt, Antimicrobial Agents and Chemotherapy, 63(1), e01793-18, 20190101
- Full genome sequence of a polyvalent bacteriophage infecting strains of Shigella, Salmonella, and Escherichia., Achives of Virology, 163(11), 3211-3211, 20181101
- Systemic method to isolate large bacteriophages for use in biocontrol of a wide-range of pathogenic bacteria, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 127(1), 73-78, 20190101
- High Prevalence of Antimicrobial Resistance in Gram-Negative Bacteria Isolated from Clinical Settings in Egypt: Recalling for Judicious Use of Conventional Antimicrobials in Developing Nations, MICROBIAL DRUG RESISTANCE, 25(3), 371-385, 20190401
- Staphylococcus aureus and bovine mastitis: molecular typing of methicillin-resistance and clinical description of infected quarters, JOURNAL OF THE HELLENIC VETERINARY MEDICAL SOCIETY, 70(2), 1511-1516, 2019
- Clinical and molecular characterization of both methicillin-resistant and-sensitive staphylococcus aureus mastitis, JOURNAL OF THE HELLENIC VETERINARY MEDICAL SOCIETY, 70(3), 1743-1748, 2019
- Genetic analysis of carbapenemase-producing Gram-negative bacteria isolated from a university teaching hospital in Egypt, INFECTION GENETICS AND EVOLUTION, 77, 202001
- Emergence of a Multidrug-Resistant Enterobacter hormaechei Clinical Isolate from Egypt Co-Harboring mcr-9 and bla(VIM-4), MICROORGANISMS, 8(4), 202004
Publications such as books
- 1997/06/00, In vivo production of oligodeoxyribonucleotides of specific sequences: application to antisense DNA, Oligonucleotides as Therapeutic Agents (John Wiley & Sons Ltd), 1997, 6, Scholarly Book, Cocompilation, 英語, Masayori Inouye, J-R Mao, Tadashi Shimaototo, Sumiko Inouye, 224-234
- 1998/07/00, Role of ribonuclease H in the biosynthesis of msDNA in Escherichia coli, The Physiological Functions of Escherichia coli RNase HI (INSERM Editions), 1998, 7, Scholarly Book, Cocompilation, 英語, Masayori Inouye, Tadashi Shimamoto, Masamitsu Shimada, Sumiko Inouye, 67-78
- 2001/03/25, 海と大地の恵みのサイエンス, 2001, 3, Textbook, Cocompilation, 日本語, 201, 116-119
- 2001/03/25, 海と大地の恵みのサイエンス, 2001, 3, Textbook, Joint work, 日本語, 201, 82-85
- 2002/03/00, Retrons, Mobile DNA II (ASM Press), 2002, 3, Scholarly Book, Cocompilation, 英語, Kunitoshi Yamanaka, Tadashi Shimaoto, Sumiko Inouye, Masayori Inouye, 784-795
- 2003/06/00, 医薬バイオテクノロジー事典, 2003, 6, Dictionary/Encyclopedia, Joint work, 日本語, 526
- 2010/04/01, 食品微生物学辞典, 2010, 4, Dictionary/Encyclopedia, Others, 日本語, 341
- 2011/11/25, 生命・食・環境のサイエンス, 2011, 11, Textbook, Joint work, 日本語, 228, 1月4日
- 2011/11/25, 生命・食・環境のサイエンス, 2011, 11, Textbook, Joint work, 日本語, 228, 172-174
- 2013/06/01, 腸炎ビブリオ〈第Ⅳ集〉, 2013, 6, Scholarly Book, Joint work, 日本語, 362, 338-345
- 2013/07/25, Bacterial Satellite DNA: A Novel Dimension in Bacterial Pathogenicity, LAP LAMBERT Academic Publishing, 2013, 7, Joint work, 英語, Rasel Das, Tadashi Shimamoto, Mohammad Arifuzzaman, 74, 74
Invited Lecture, Oral Presentation, Poster Presentation
- First report of Klebsiella pneumoniae co-producing NDM-1 and VIM-1 carbapenemases from a meat sample in Japan, Tadashi Shimamoto, Tadashi Shimamoto, Joint Event on 4th International Conference on APPLIED MICROBIOLOGY, ANTIBIOTICS, ANTIMICROBIALS AND BENEFICIAL MICROBES, 2019/05/20, With Invitation, English, CONFERENCE SERIES LLC LTD, Tokyo, Japan
Awards
- 2020/09/02, Excellent Paper Award of The Society for Biotechnology, Japan, The Society for Biotechnology, Japan