TOMOHIKO SAKUDA

Last Updated :2025/01/07

Affiliations, Positions
Hiroshima University Hospital(Medical), Assistant Professor
E-mail
saakuudahiroshima-u.ac.jp
Self-introduction
I specialize in clinical and basic bone and soft tissue tumors at Hiroshima University Orthopedic Surgery. In clinical practice, I am familiar with chemotherapy as well as surgery. Basically, we are conducting research on the treatment of malignant tumors using oncolytic viruses.

Basic Information

Major Professional Backgrounds

  • 2020/04, Department of Orthpaedic Surgery, Hiroshima University, Assistant Professor
  • 2010/04, 2012/03, Matsuyama Red Cross Hospital, medical intern
  • 2012/04, 2014/03, Hiroshima City Hiroshima Citizens Hospital, Orthopedic doctor
  • 2014/04, 2016/03, Saiseikai Kure Hospital, Orthopedic doctor
  • 2016/04, 2020/03, Department of Orthopaedic Surgery, Hiroshima University, clinical staff

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical & Health Sciences , Japan, 2016/04, 2020/03
  • Ehime University, Japan, 2004/04, 2010/03

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Orthopaedic surgery

Research Keywords

  • Osteosarcoma
  • Oncolytic Virus
  • Orthopedics

Affiliated Academic Societies

  • The Central Japan Association of Orthopaedic Surgery & Traumatology
  • The Chugoku-Shikoku Orthopaedic Association
  • The Japanese Orthopaedic Association

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, Year, Clinical diagnosis and treatment II
  2. 2024, Undergraduate Education, Intensive, Practice of Medicine I

Research Activities

Academic Papers

  1. Myopericytoma of the patella with local recurrence and patellectomy: A case report, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 115, 202402
  2. Synergistic VSV Virotherapy and Carbon Nanotube Photothermal Therapy for Osteosarcoma in Murine Models, ANTICANCER RESEARCH, 44(1), 99-105, 202401
  3. Synergistic VSV Virotherapy and Carbon Nanotube Photothermal Therapy for Osteosarcoma in Murine Models, Anticancer Research, 44(1), 99-105, 2024
  4. Myopericytoma of the patella with local recurrence and patellectomy: A case report, International Journal of Surgery Case Reports, 2024
  5. Functional outcome of campanacci grade 3 giant cell tumours of distal radius after resection and reconstruction with ulnar translocation technique: a case series, ANNALS OF MEDICINE AND SURGERY, 85(6), 3179-3186, 202306
  6. Metastatic patellar bone tumor due to gastric cancer resembling a primary or secondary aneurysmal bone cyst: A case report, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 108, 202307
  7. Oncolytic Effect of a Recombinant Vesicular Stomatitis Virus Encoding a Tumor-suppressor MicroRNA in an Osteosarcoma Mouse Model, ANTICANCER RESEARCH, 43(3), 1185-1191, 202303
  8. Incomplete Atypical Femoral Fracture Treated by Prophylactic Intramedullary Nail Fixation: A Case Series, Cureus, 2022
  9. Giant cell tumor of the cervical spine treated by carbon ion radiotherapy: A case report, Medicine (Baltimore), 2021
  10. Tuberculosis of the knee masquerading as pigmented villonodular synovitis: Report of two cases, International Journal of Surgery Case Reports, 2021
  11. Utility of intraoperative magnetic resonance imaging for giant cell tumor of bone after denosumab treatment: a pilot study, Acta Radiologica, 2021
  12. ★, Novel Near-Infrared Fluorescence-Guided Surgery With Vesicular Stomatitis Virus for Complete Surgical Resection of Osteosarcomas in Mice., Journal of Orthopaedic Research, 37(5), 1192-1201, 2019
  13. Rapidly growing Fibro-osseous pseudotumor of the digit A case report, Medicine (Baltimore), 99(28), 20200710
  14. Coexistence of giant cell tumor of tendon sheath and enchondroma in the middle phalanx of the little finger mimicking a malignant tumor: A case report., Oncology Letters, 17(2), 1969-1973, 2019
  15. Conventional 99mTc-(hydroxy) methylene dishosphate remains useful to predict osteosarcoma response to neoadjuvant chemotherapy: Individual patient data and aggregate data meta-analyses., Medicine (Baltimore), 97(51), 2018
  16. A meta-analysis supports core needle biopsy by radiologists for better histological diagnosis in soft tissue and bone sarcomas., Medicine (Baltimore), 97(29), 2018
  17. Effect of Continuous Compression Stimulation on Pressure-Pain Threshold and Muscle Spasms in Older Adults With Knee Osteoarthritis: A Randomised Trial., J Manipulative Physiol Ther, 41(4), 315-322, 2018
  18. Metastatic Tumor Cells Detection and Anti-Metastatic Potential with Vesicular Stomatitis Virus in Immunocompetent Murine Model of Osteosarcoma., 36(9), 2562-2569, 2018
  19. Development of an Oncolytic Recombinant Vesicular Stomatitis Virus Encoding a Tumor-suppressor MicroRNA, Anticancer Research, 40(11), 6319-6325, 202011
  20. Granulocyte Colony-Stimulating Factor-Induced Aortitis with Lung Injury, Splenomegaly, and a Rash During Treatment for Recurrent Extraosseous Mucinous Chondrosarcoma, Internal Medicine, 2020
  21. Extraskeletal Ewing sarcoma attached to the ulnar nerve: A case report, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 80, 2021
  22. Tuberculosis of the knee masquerading as pigmented villonodular synovitis: Report of two cases, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 88, 202111
  23. Giant cell tumor of the cervical spine treated by carbon ion radiotherapy A case report, MEDICINE, 100(41), 20211015
  24. Utility of intraoperative magnetic resonance imaging for giant cell tumor of bone after denosumab treatment: a pilot study, ACTA RADIOLOGICA, 63(2), 176-181, 202202

Publications such as books

  1. 2020/10, Journal of Joint Surgery, malignant soft tissue tumors, MRI, biopsy, 2020, 10, Textbook, Joint work, 14-23

Invited Lecture, Oral Presentation, Poster Presentation

  1. Novel near-infrared fluorescence-guided surgery with vesicular stomatitis virus for complete surgical resection of osteosarcomas in mice, Tomohiko Sakuda, Tadahiko Kubo, Muhammad Petrus Johan, Taisuke Furuta, Mitsuo Ochi, Nobuo Adachi, 19th Grand Round Musculoskeletal Oncology (Indonesia), 2019/03/08, With Invitation, English, 1st winner of poster presentation

Awards

  1. 2019, 1st winner of poster presentation, 19th Grand Round Musculoskeletal Oncology (Indonesia), Novel near-infrared fluorescence-guided surgery with vesicular stomatitis virus for complete surgical resection of osteosarcomas in mice.

External Funds

Acceptance Results of Competitive Funds

  1. 2019/04, 2020/03