TOMOHIKO SAKUDA

Last Updated :2026/04/03

Affiliations, Positions
Hiroshima University Hospital, Associate Professor/Lecturer
E-mail
saakuudahiroshima-u.ac.jp
Self-introduction
I specialize in clinical and basic bone and soft tissue tumors at Hiroshima University Orthopedic Surgery. In clinical practice, I am familiar with chemotherapy as well as surgery. Basically, we are conducting research on the treatment of malignant tumors using oncolytic viruses.

Basic Information

Major Professional Backgrounds

  • 2010/04, 2012/03, Matsuyama Red Cross Hospital, medical intern
  • 2012/04, 2014/03, Hiroshima City Hiroshima Citizens Hospital, Orthopedic doctor
  • 2014/04, 2016/03, Saiseikai Kure Hospital, Orthopedic doctor
  • 2016/04/01, 2020/03/31, Department of Orthopaedic Surgery, Hiroshima University, Hospital, Clinical Staff
  • 2020/04/01, 2025/03/31, Department of Orthpaedic Surgery, Hiroshima University, Hospital, Assistant Professor

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical & Health Sciences , Japan, 2016/04, 2020/03
  • Ehime University, Japan, 2004/04, 2010/03

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Orthopaedic surgery

Research Keywords

  • Osteosarcoma
  • Oncolytic Virus
  • Orthopedics

Affiliated Academic Societies

  • The Central Japan Association of Orthopaedic Surgery & Traumatology
  • The Chugoku-Shikoku Orthopaedic Association
  • The Japanese Orthopaedic Association

Research Activities

Academic Papers

  1. Cholesterol Crystal-induced Arthritis, Internal Medicine, 64(12), 1946-1947, 20250615
  2. Preventive Approach to Phantom Limb Pain in Lower Limb Ablation Surgery: A Systematic Review, ORTHOPEDIC REVIEWS, 17, 2025
    Link to Paper Search Results by DOI
  3. Intraoperative MRI for giant cell tumor of bone after denosumab and other selected tumors: A pilot study, ACTA RADIOLOGICA OPEN, 15(1), 202601
    Link to Paper Search Results by DOI
  4. High Antitumor Effects and Reduced Side Effects of Doxorubicin Prodrug Active Only Under Hypoxic Conditions, ANTICANCER RESEARCH, 45(7), 2905-2916, 202507
    Link to Paper Search Results by DOI
  5. Case report on an extremely rare type of ependymoma arising from the thigh, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 123, 202410
    Link to Paper Search Results by DOI
  6. Myopericytoma of the patella with local recurrence and patellectomy: A case report, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 115, 202402
    Link to Paper Search Results by DOI
  7. Synergistic VSV Virotherapy and Carbon Nanotube Photothermal Therapy for Osteosarcoma in Murine Models, ANTICANCER RESEARCH, 44(1), 99-105, 202401
    Link to Paper Search Results by DOI
  8. Synergistic VSV Virotherapy and Carbon Nanotube Photothermal Therapy for Osteosarcoma in Murine Models, Anticancer Research, 44(1), 99-105, 2024
  9. Myopericytoma of the patella with local recurrence and patellectomy: A case report, International Journal of Surgery Case Reports, 2024
  10. Functional outcome of campanacci grade 3 giant cell tumours of distal radius after resection and reconstruction with ulnar translocation technique: a case series, ANNALS OF MEDICINE AND SURGERY, 85(6), 3179-3186, 202306
    Link to Paper Search Results by DOI
  11. Metastatic patellar bone tumor due to gastric cancer resembling a primary or secondary aneurysmal bone cyst: A case report, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 108, 202307
    Link to Paper Search Results by DOI
  12. Oncolytic Effect of a Recombinant Vesicular Stomatitis Virus Encoding a Tumor-suppressor MicroRNA in an Osteosarcoma Mouse Model, ANTICANCER RESEARCH, 43(3), 1185-1191, 202303
    Link to Paper Search Results by DOI
  13. Incomplete Atypical Femoral Fracture Treated by Prophylactic Intramedullary Nail Fixation: A Case Series, Cureus, 2022
    Link to Paper Search Results by DOI
  14. Giant cell tumor of the cervical spine treated by carbon ion radiotherapy: A case report, Medicine (Baltimore), 2021
  15. Tuberculosis of the knee masquerading as pigmented villonodular synovitis: Report of two cases, International Journal of Surgery Case Reports, 2021
  16. Utility of intraoperative magnetic resonance imaging for giant cell tumor of bone after denosumab treatment: a pilot study, Acta Radiologica, 2021
  17. ★, Novel Near-Infrared Fluorescence-Guided Surgery With Vesicular Stomatitis Virus for Complete Surgical Resection of Osteosarcomas in Mice., Journal of Orthopaedic Research, 37(5), 1192-1201, 2019
  18. Rapidly growing Fibro-osseous pseudotumor of the digit A case report, Medicine (Baltimore), 99(28), 20200710
    Link to Paper Search Results by DOI
  19. Coexistence of giant cell tumor of tendon sheath and enchondroma in the middle phalanx of the little finger mimicking a malignant tumor: A case report., Oncology Letters, 17(2), 1969-1973, 2019
  20. Conventional 99mTc-(hydroxy) methylene dishosphate remains useful to predict osteosarcoma response to neoadjuvant chemotherapy: Individual patient data and aggregate data meta-analyses., Medicine (Baltimore), 97(51), 2018
  21. A meta-analysis supports core needle biopsy by radiologists for better histological diagnosis in soft tissue and bone sarcomas., Medicine (Baltimore), 97(29), 2018
  22. Effect of Continuous Compression Stimulation on Pressure-Pain Threshold and Muscle Spasms in Older Adults With Knee Osteoarthritis: A Randomised Trial., J Manipulative Physiol Ther, 41(4), 315-322, 2018
  23. Metastatic Tumor Cells Detection and Anti-Metastatic Potential with Vesicular Stomatitis Virus in Immunocompetent Murine Model of Osteosarcoma., 36(9), 2562-2569, 2018
  24. Development of an Oncolytic Recombinant Vesicular Stomatitis Virus Encoding a Tumor-suppressor MicroRNA, Anticancer Research, 40(11), 6319-6325, 202011
  25. Granulocyte Colony-Stimulating Factor-Induced Aortitis with Lung Injury, Splenomegaly, and a Rash During Treatment for Recurrent Extraosseous Mucinous Chondrosarcoma, Internal Medicine, 2020
  26. Extraskeletal Ewing sarcoma attached to the ulnar nerve: A case report, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 80, 2021
    Link to Paper Search Results by DOI
  27. Tuberculosis of the knee masquerading as pigmented villonodular synovitis: Report of two cases, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 88, 202111
    Link to Paper Search Results by DOI
  28. Giant cell tumor of the cervical spine treated by carbon ion radiotherapy A case report, MEDICINE, 100(41), 20211015
    Link to Paper Search Results by DOI
  29. Utility of intraoperative magnetic resonance imaging for giant cell tumor of bone after denosumab treatment: a pilot study, ACTA RADIOLOGICA, 63(2), 176-181, 202202
    Link to Paper Search Results by DOI

Publications such as books

  1. 2020/10, Journal of Joint Surgery, malignant soft tissue tumors, MRI, biopsy, 2020, 10, Textbook, Joint work, 14-23

Invited Lecture, Oral Presentation, Poster Presentation

  1. Novel near-infrared fluorescence-guided surgery with vesicular stomatitis virus for complete surgical resection of osteosarcomas in mice, Tomohiko Sakuda, Tadahiko Kubo, Muhammad Petrus Johan, Taisuke Furuta, Mitsuo Ochi, Nobuo Adachi, 19th Grand Round Musculoskeletal Oncology (Indonesia), 2019/03/08, With Invitation, English, 1st winner of poster presentation

Awards

  1. 2019, 1st winner of poster presentation, 19th Grand Round Musculoskeletal Oncology (Indonesia), Novel near-infrared fluorescence-guided surgery with vesicular stomatitis virus for complete surgical resection of osteosarcomas in mice.

External Funds

Acceptance Results of Competitive Funds

  1. 2019/04, 2020/03