KIMINORI MATUBARA

Last Updated :2024/02/01

Affiliations, Positions
Graduate School of Humanities and Social Sciences, Professor
E-mail
kmatsubahiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Doctor of Agriculture, Hiroshima University
  • Master of Agriculture, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Education : Life-long Activities Education : Human Life Sciences Education
  • [Master's Program] Graduate School of Humanities and Social Sciences : Division of Educational Sciences : Educational Design for Teacher Educators Program
  • [Doctoral Program] Graduate School of Humanities and Social Sciences : Division of Educational Sciences : Educational Design for Teacher Educators Program

In Charge of Primary Major Programs

  • Human Life Sciences Education

Research Fields

  • Agricultural sciences;Agricultural chemistry;Food science
  • Complex systems;Human life science;Eating habits

Research Keywords

  • functional food
  • lymphangiogenesis
  • angiogenesis
  • Anti-aging

Educational Activity

Course in Charge

  1. 2023, Undergraduate Education, 3Term, Science and Culture of Daily Life in Japan
  2. 2023, Undergraduate Education, 3Term, Introduction to Human Life Sciences(Home Economics)Education
  3. 2023, Undergraduate Education, 4Term, Nutritional Sciences in dietary habits
  4. 2023, Undergraduate Education, 1Term, Introduction to Dietary Life
  5. 2023, Undergraduate Education, 3Term, Food Science
  6. 2023, Undergraduate Education, 1Term, Sciences of food materials
  7. 2023, Undergraduate Education, 2Term, Experiment in Food Sciences
  8. 2023, Undergraduate Education, Second Semester, Introduction Seminar on Dietary Life
  9. 2023, Undergraduate Education, Second Semester, Graduation Thesis
  10. 2023, Undergraduate Education, Second Semester, Practical Seminar for the Teaching Profession
  11. 2023, Graduate Education (Doctoral Program) , Second Semester, Research into Teaching Practice
  12. 2023, Graduate Education (Master's Program) , 1Term, Research Methods and Ethics for Educational Sciences
  13. 2023, Graduate Education (Master's Program) , First Semester, Special Study in Human Life Sciences Education A
  14. 2023, Graduate Education (Master's Program) , Second Semester, Special Study in Human Life Sciences Education A
  15. 2023, Graduate Education (Master's Program) , 1Term, Basic Course in Teaching Material Design for Life and Science (Home Economics)
  16. 2023, Graduate Education (Master's Program) , 3Term, Advanced Course in Teaching Material Design for Life and Science (Home Economics)
  17. 2023, Graduate Education (Doctoral Program) , First Semester, Special Study
  18. 2023, Graduate Education (Doctoral Program) , Second Semester, Special Study

Research Activities

Academic Papers

  1. Antiangiogenic activity of 3,4-seco-cycloartane triterpenes from Thai Gardenia spp. and their semi-synthetic analogs, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22(1), 512-517, 20120101
  2. Antiangiogenic Effect of Carnosic Acid and Carnosol, Neuroprotective Compounds in Rosemary Leaves, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 76(1), 115-119, 201201
  3. Antiangiogenic Effect of Chamigrane Endoperoxides from a Thai Mangrove-Derived Fungus, JOURNAL OF NATURAL PRODUCTS, 74(10), 2290-2294, 201110
  4. Docosahexaenoic- and Eicosapentaenoic Acid-bound Lysophospholipids are More Effective in Suppressing Angiogenesis than Conjugated Docosahexaenoic Acid, JOURNAL OF OLEO SCIENCE, 61(8), 427-432, 201208
  5. Cytotoxic and Anti-angiogenic Properties of Minor 3,4-seco-Cycloartanes from Gardenia sootepensis Exudate, CHEMICAL & PHARMACEUTICAL BULLETIN, 60(12), 1538-1543, 201212
  6. Glutamine Protects Intestinal Barrier Function of Colon Epithelial Cells from Ethanol by Modulating Hsp70 Expression, PHARMACOLOGY, 91(1-2), 104-111, 2013
  7. Marine algal carotenoids inhibit angiogenesis by down-regulating FGF-2-mediated intracellular signals in vascular endothelial cells, MOLECULAR AND CELLULAR BIOCHEMISTRY, 380(1-2), 1-9, 201308
  8. Antiangiogenetic effects of anthranoids from Alternaria sp., an endophytic fungus in a Thai medicinal plant Erythrina variegata, PHYTOMEDICINE, 20(10), 918-922, 20130715
  9. Catechin conjugated with fatty acid inhibits DNA polymerase and angiogenesis., DNA and Cell Biology, 25(2), 95-103, 20060401
  10. Structure-activity relationship of anticoagulant and antiangiogenic sulfated galactan from a marine green alga, Codium cylindricum., Recent Progress in Medicinal Plants, 18, 377-386, 20060401
  11. Antiangiogenic activity of brown algae fucoxanthin and its deacetylated product, fucoxanthinol., Journal of Agricultural and Food Chemistry, 54(26), 9805-9810, 20061201
  12. Epicatechin conjugated with fatty acid is a potent inhibitor of DNA polymerase and angiogenesis., Life Sciences, 80, 1578-1585, 20070401
  13. Inhibitory effects of vitamin K3 on DNA polymerase and angiogenesis, International Journal of Molecular Medicine, 22(3), 381-387, 20081103
  14. Expression of sphingosine-1-phosphate receptor 1 in mantle cell lymphoma., Mol Pathol, 23, 439-449, 20100301
  15. Inhibitory effect of carotenoids on the degranulation of mast cells via suppression of antigen-induced aggregation of high affinity IgE receptors., J Biol Chem, 284, 28172-28179, 20091001
  16. Primary structures of two hemagglutinins from the marine red alga, Hypnea japonica, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1474(2), 226-236, 20000406
  17. Immunohistochemical detection of sphingosine-1-phosphate receptor 1 in vascular and lymphatic endothelial cells, JOURNAL OF MOLECULAR HISTOLOGY, 39(5), 527-533, 200810
  18. 1,4-Naphthoquinone is a potent inhibitor of human cancer cell growth and angiogenesis, CANCER LETTERS, 278(1), 34-40, 20090608
  19. Strict Binding Specificity of Small-Sized Lectins from the Red Alga Hypnea japonica for Core (alpha 1-6) Fucosylated N-Glycans, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 73(4), 912-920, 200904
  20. Expression of sphingosine-1-phosphate receptor 1 in mantle cell lymphoma, MODERN PATHOLOGY, 23(3), 439-449, 201003
  21. PTHrP Regulates Angiogenesis and Bone Resorption via VEGF Expression, ANTICANCER RESEARCH, 30(7), 2755-2767, 201007
  22. Synthesis and biological evaluation of vitamin K derivatives as angiogenesis inhibitor, BIOORGANIC & MEDICINAL CHEMISTRY, 18(17), 6305-6309, 20100901
  23. Anti-angiogenic effect of siphonaxanthin from green alga, Codium fragile, PHYTOMEDICINE, 17(14), 1140-1144, 20101201
  24. Consumption of vitamin B6 reduces colonic damage and protein expression of HSP70 and HO-1, the anti-tumor targets, in rats exposed to 1,2-dimethylhydrazine, ONCOLOGY LETTERS, 2(6), 1243-1246, 2011
  25. Phosphatidylcholine hydroperoxide promotes VEGF-induced angiogenesis in endothelial cells and rat aorta ring cultures, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1810(12), 1205-1211, 201112
  26. Cecal Succinate Elevated by Some Dietary Polyphenols May Inhibit Colon Cancer Cell Proliferation and Angiogenesis, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 62(24), 5589-5594, 20140618
  27. Inhibitory Effect of Carotenoids on the Degranulation of Mast Cells via Suppression of Antigen-induced Aggregation of High Affinity IgE Receptors, JOURNAL OF BIOLOGICAL CHEMISTRY, 284(41), 28172-28179, 20091009
  28. Studies on macromolecules active for blood coagulation and fibrinolysis from marine algae, Bulletin of the Japanese Society of Scientific Fisheries, 69(4), 550-553, 20030715
  29. Carnosic acid protects starvation-induced SH-SY5Y cell death through Erk1/2 and Akt pathways, autophagy, and FoxO3a., Int J Food Sci Nutr, 67, 977-982, 20161201
  30. Inhibitory effects of pisiferic acid on angiogenesis and lymphangiogenesis., Planta Medica Int Open, 1, 1-4, 20160822
  31. Carnosic acid protects starvation-induced SH-SY5Y cell death through Erk1/2 and Akt pathways, autophagy, and FoxO3a, INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, 67(8), 977-982, 2016
  32. The delaying effect of alpha- glycerophosphocholine on senescence, transthyretin deposition, and osteoarthritis in senescence-accelerated mouse prone 8 mice, Bioscience, Biotechnology, and Biochemistry, 82(4), 647-653, 20180501
  33. Anti-Angiogenic Activity of Rotenoids from the Stems of Derris trifoliata., Planta Medica, 84(11), 779-785, 2018
  34. Carnosic acid attenuates cartilage degeneration through induction of heme oxygenase-1 in human articular chondrocytes, Eur J Pharmacol, 830, 1-8, 20180417
  35. Carnosic acid attenuates cartilage degeneration through induction of heme oxygenase-1 in human articular chondrocytes, EUROPEAN JOURNAL OF PHARMACOLOGY, 830, 1-8, 20180705
  36. Anti-diabetic effect of S-adenosylmethionine and alpha-glycerophosphocholine in KK-A(y) mice, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 83(4), 747-750, 20190403
  37. High Mannose Binding Lectin (PFL) from Pseudomonas fluorescens Down-Regulates Cancer-Associated Integrins and Immune Checkpoint Ligand B7-H4, CANCERS, 11(5), 201905
  38. Sake cake (sake-kasu) ingestion increases branched-chain amino acids in the plasma, muscles, and brains of senescence-accelerated mice prone 8, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 83(8), 1490-1497, 20190803
  39. Effects of Rice Wine Lees on Cognitive Function in Community-Dwelling Physically Active Older Adults: A Pilot Randomized Controlled Trial, JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE, 7(2), 95-103, 202004
  40. Efficacy of Long-Term Feeding of alpha-Glycerophosphocholine for Aging-Related Phenomena in Old Mice, GERONTOLOGY, 66(3), 275-285, 202005
  41. Anti-stress effects of rosemary (Rosmarinus officinalis L.) leaf extract on intestinal goblet cells and immobility of forced-swimming test in BALB/c mice, BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, 20200727
  42. Alpha-Glycerylphosphorylcholine Increases Motivation in Healthy Volunteers: A Single-Blind, Randomized, Placebo-Controlled Human Study, NUTRIENTS, 13(6), 202106